Exon identity established through differential antagonism between exonic splicing silencer-bound hnRNP A1 and enhancer-bound SR proteins

Molecular Cell

Volumn 8, Issue 6, 2001, Pages 1351-1361

  Zhu, Jun ^a,b   Mayeda, Akila ^c   Krainer, Adrian R ^a  

^a Simons Center for Quantitative Biology   (United States)

^b STONY BROOK UNIVERSITY   (United States)

^c UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN; PROTEIN; PROTEIN SR; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; BINDING SITE; CONTROLLED STUDY; ENHANCER REGION; EXON; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS; PROTEIN BINDING; PROTEIN PROCESSING; SILENCER GENE;

HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS 1;

EID: 0035691667     PISSN: 10972765     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1097-2765(01)00409-9     Document Type: Article

References (43)

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3. RNA splicing at human immunodeficiency virus type 1 3′ splice site A2 is regulated by binding of hnRNP A/B proteins to an exonic splicing silencer element
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26. Mammalian in vitro splicing assays
27. Function of conserved domains of hnRNP A1 and other hnRNP A/B proteins
28. Substrate specificities of SR proteins in constitutive splicing are determined by their RNA recognition motifs and composite pre-mRNA exonic elements
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42. The hnRNP A1 protein regulates HIV-1 tat splicing via a novel intron silencer element
43. Pre-mRNA splicing in the absence of an SR protein RS domain