Impaired myogenic response and autoregulation of cerebral blood flow is rescued in CYP4a1 transgenic Dahl salt-sensitive rat

American Journal of Physiology - Regulatory Integrative and Comparative Physiology

Volumn 308, Issue 5, 2015, Pages R379-R390

  Fan, Fan ^a   Geurts, Aron M ^b   Murphy, Sydney R ^a   Pabbidi, Mallikarjuna R ^a   Jacob, Howard J ^b   Roman, Richard J ^a  

^a UNIVERSITY OF MISSISSIPPI SCHOOL OF MEDICINE   (United States)

^b MEDICAL COLLEGE OF WISCONSIN   (United States)

Author keywords

Autoregulation of cerebral blood flow; Cerebral circulation; CYP4A; Middle cerebral artery; Myogenic response

Indexed keywords

20 HYDROXYICOSATETRAENOIC ACID; CYTOCHROME P450 4A1; 20-HYDROXY-5,8,11,14-EICOSATETRAENOIC ACID; CYTOCHROME P450 4A; HYDROXYICOSATETRAENOIC ACID; SALT INTAKE; SLEEPING BEAUTY TRANSPOSASE, HUMAN; TRANSPOSASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; AUTOREGULATION; BLOOD BRAIN BARRIER; BRAIN ARTERY; BRAIN BLOOD FLOW; BRAIN BLOOD VESSEL; CONTROLLED STUDY; DAHL SALT SENSITIVE RAT; FEMALE; HUMAN; HUMAN CELL; MALE; MIDDLE CEREBRAL ARTERY; NONHUMAN; PRIORITY JOURNAL; RAT; ANIMAL; ARTERIAL PRESSURE; BRAIN CIRCULATION; CAPILLARY PERMEABILITY; DAHL RAT; DISEASE MODEL; ENZYMOLOGY; GENETICS; GENOTYPE; HOMEOSTASIS; HYPERTENSION; LEWIS RAT; METABOLISM; PATHOPHYSIOLOGY; PHENOTYPE; SALT INTAKE; TRANSGENIC RAT; VASCULAR REMODELING; VASOCONSTRICTION;

ANIMALS; ARTERIAL PRESSURE; BLOOD-BRAIN BARRIER; CAPILLARY PERMEABILITY; CEREBROVASCULAR CIRCULATION; CYTOCHROME P-450 CYP4A; DISEASE MODELS, ANIMAL; GENOTYPE; HOMEOSTASIS; HYDROXYEICOSATETRAENOIC ACIDS; HYPERTENSION; MIDDLE CEREBRAL ARTERY; PHENOTYPE; RATS, INBRED DAHL; RATS, INBRED LEW; RATS, TRANSGENIC; SODIUM CHLORIDE, DIETARY; TRANSPOSASES; VASCULAR REMODELING; VASOCONSTRICTION;

EID: 84923860726     PISSN: 03636119     EISSN: 15221490     Source Type: Journal    
DOI: 10.1152/ajpregu.00256.2014     Document Type: Article

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