Hypertensive cerebral small vessel disease and stroke

Brain Pathology

Volumn 12, Issue 3, 2002, Pages 358-370

  Lammie, G Alistair ^a  

^a CARDIFF UNIVERSITY   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

AUTOPSY; BRAIN BLOOD VESSEL; BRAIN INFARCTION; BRAIN INJURY; CONFERENCE PAPER; CONFUSION; GENETIC RISK; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; INTRACRANIAL HYPERTENSION; MOLECULAR GENETICS; PROTEIN LOCALIZATION; RISK FACTOR; STROKE; BRAIN ATHEROSCLEROSIS; BRAIN HEMORRHAGE; PATHOLOGY; PATHOPHYSIOLOGY; REVIEW;

CEREBRAL INFARCTION; HUMANS; INTRACRANIAL ARTERIOSCLEROSIS; INTRACRANIAL HEMORRHAGE, HYPERTENSIVE;

EID: 0036019163     PISSN: 10156305     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1750-3639.2002.tb00450.x     Document Type: Conference Paper

References (131)

1. The prevalence of ulcerated plaques in the aortic arch in patients with stroke
2. Spontaneous intracerebral haemorrhage: A clinico-pathological report
3. Primary intracerebral hemorrhage and heart weight: A clinicopathologic case-control review of 218 patients
4. Cerebrovascular disease: II. The smaller intracerebral arteries
5. Cerebrovascular disease: III. The intracerebral arterioles
6. A prospective study of acute cerebrovascular disease in the community: The Oxfordshire Community Stroke Project 1981-1986; II: Incidence, case fatality rates and overall outcome at one year of cerebral infarction, primary intracerebral and subarachnoid haemorrhage
7. The natural history of lacunar infarction: The Oxfordshire Community Stroke Project
8. Mechanics and composition of arterioles in brain stem and cerebellum
9. Remodeling of cerebral arterioles in chronic hypertension
10. Expanding cerebellar lacunes due to dilatation of the perivascular space associated with Binswanger's subcortical arteriosclerotic encephalopathy
11. Association infarctus lacunaire et hematome intra-cerebral
12. Field of needs. The genetics of stroke
13. The plurality of subcortical infarction
14. Risk factors for lacunar infarction
15. Frequency and degree of carotid stenosis in small centrum ovale infarcts as compared to lacunar infarcts
16. Cigarette smoking, hypertension and the risk of subarachnoid hemorrhage: A population-based case-control study
17. Epidemiology of stroke
18. Hypertension as a risk factor for spontaneous intracerebral hemorrhage
19. Pure subcortical arteriosclerotic encephalopathy (Binswanger's disease): A clinicopathologic study. Part 2. Pathological features
20. Morbid effects of vasopressin on the organs and vessels of rats
21. The pathogenesis of hypertensive encephalopathy and its relation to the malignant phase of hypertension; experimental evidence from the hypertensive rat
22. Intracerebral hemorrhage revisited
23. Intracranial branch atheromatous disease: A neglected, understudied and underused concept
24. Hypertensive intracerebral haemorrhage
25. A combined haematoxylin-eosin, alkaline phosphatase and high resolution microradiographic study of lacunes
26. The Charcot-Bouchard aneurysm controversy: Impact of a new histologic technique
27. The role of transgenic animals in cerebral ischemia
28. Hypertensive encephalopathy: A clinicopathologic study of 20 cases
29. The influence of hypertension and other haemodynamic factors in atherogenesis
30. Intracerebral microaneurysms and small cerebrovascular lesions
31. The occurrence and significance of intracerebral micro-aneurysms
32. The pathophysiology of acute coronary syndromes
33. Internal borderzone infarction. A marker for severe stenosis in patients with symptomatic internal carotid artery disease
34. "Expanding cerebral lacunae" in a hypertensive patient with normal pressure hydrocephalus
35. An autopsy study of the incidence of lacunes in relation to age, hypertension, and arteriosclerosis
36. Association between the Glu298Asp polymorphism in the endothelial constitutive nitric oxide synthase gene and brain infarction
37. Pathologic correlates of incidental MRI white matter signal hyperintensities
38. Hypertensive fibrinoid arteritis of the brain and gross cerebral hemorrhage. A form of "hyalinosis"
39. Precursors of extracranial carotid atherosclerosis in the Framingham Study
40. Lacunes: Small, deep cerebral infarcts
41. The arterial lesions underlying lacunes
42. Cerebral miliary aneurysms in hypertension
43. Pathological observations in hypertensive cerebral hemorrhage
44. Bilateral occlusion of the basilar artery branches
45. Thalamic pure sensory stroke: A pathologic study
46. Capsular infarcts. The underlying vascular lesions
47. Lacunar infarcts - A review
48. Basilar artery branch occlusion: A cause of pontine infarction
49. Lateral medullary infarction extending to the lower pons
50. Cerebrovascular responses to pathophysiological insult in diabetic rats
51. Prognostic factors in patients with intracerebral hematoma
52. Cerebrovascular lesions in stroke prone spontaneously hypertensive rats
53. Cerebral microangiopathy in stroke-prone spontaneously hypertensive rats. An immunohistochemical and ultrastructural study
54. Fatal hypertensive intracerebral hematomas: A survey of the pathological anatomy of 393 cases
55. The decreasing incidence of primary intracerebral hemorrhage: A population study
56. Medullary arteries in aging and dementia
57. Internal borderzone infarction in patients with ischaemic stroke
58. Intracerebral hemorrhage: Pathology of selected topics
59. The emerging concept of vascular remodelling
60. Miliary aneurysms in the brain
61. Hypertensive arteriolar necrosis revisited
62. Studies on the pathogenesis of hyperensive vascular disease. Effects of high-pressure intra-arterial injections in rats
63. Hypothesis - Origin of lacunes
64. Pathology of intracerebral hemorrhage
65. Prevalence of risk factors in spontaneous intracerebral hemorrhage
66. Vascular Diseases
67. Controlled hypertension, a transgenic toggle switch reveals differential mechanisms underlying vascular disease
68. Genetic mapping of modified loci affecting malignant hypertension in TGR mRen rats
69. The role of oedema in lacune formation
70. Pathology of small vessel stroke
71. Nonhypertensive cerebral small-vessel disease - An autopsy study
72. Incomplete lacunar infarction (Type 1b lacunes)
73. Stress-related primary intracerebral haemorrhage - Autopsy clues to underlying mechanism
74. Recently occluded intracranial and extracranial carotid arteries. Relevance of the unstable atherosclerotic plaque
75. Small centrum ovale infarcts - A pathological study
76. The upper limit of autoregulation of cerebral blood flow on the pathogenesis of hypertensive encephalopathy
77. Clinico-pathologic correlations of cranial magnetic resonance imaging of periventricular white matter
78. Cerebrovascular diseases in a fixed population of Hiroshima and Nagasaki, with special reference to relationship between type and risk factors
79. Does hypertension confer a hypercoagulable state?
80. Are hypertension or cardiac embolism likely causes of lacunar infarction?
81. Prevalence of atherosclerotic involvement of the internal carotid artery in hypertensive patients
82. Structural and vascular permeability abnormalities associated with lacunes of the human brain
83. Effects of acutely induced hypertension in cats on pial arteriolar caliber, local cerebral flow, and the blood-brain barrier
84. The epidemiological association between blood pressure and stroke: Implications for primary and secondary prevention
85. Des foyers lacunaires de disintegration et de differents etats cavitaires du cerveau
86. Angiotensin - Converting enzyme gene deletion polymorphism: A new risk factor for lacunar stroke but not carotid atheroma
87. Stroke in pregnancy and the peurperium
88. Cerebrovascular diseases and their underlying vascular lesions in Hisayama, Japan - A pathological study of autopsy cases
89. Association of the D allele of the angiotensin I converting enzyme polymorphism with malignant vascular injury
90. The apolipoprotein E e2 allele and the pathological features in cerebral amyloid angiopathy-related hemorrhage
91. The fallacy of the lacune hypothesis
92. The pathogenesis of single penetrator infarcts
93. Impaired cerebrovascular reactivity as a risk marker for first-ever lacunar infarction. A case control study
94. Inhibition of tissue angiotensin converting enzyme activity prevents malignant hypertension in TGR (mRen2) 27
95. Perivascular encephalolysis
96. High frequency of apolipoprotein E e2 in patients with cerebral hemorrhage due to cerebral amyloid angiopathy
97. Cerebral haemorrhage
98. Pathology of small artery disease
99. Pathogenesis of leukoaraiosis: A review
100. Giant cerebral lacunae due to dilatation of the perivascular space: A case report
101. Cerebral lacunae. A proposed new classification
102. Le concept de lacune cerebrale de 1838 a nos jours
103. Perivascular spaces in the basal ganglia of the human brain: Their relationship to lacunes
104. Pathogenesis of lacunar infarcts and small deep infarcts
105. Frequency and location of microbleeds in patients with primary intracerebral hemorrhage
106. Miliary aneurysms and "fibrinoid" degeneration of cerebral blood vessels
107. The importance of fibrinoid necrosis as the cause of cerebral hemorrhage in hypertension. Commentary
108. Observations on intracerebral aneurysms
109. The high cost of not funding stroke research: A comparison with heart disease and cancer
110. Chromosomal mapping of quantitative trait loci contributing to stroke in a rat model of complex human disease
111. Spontaneous intracranial haemorrhage
112. Subarachnoid and intracerebral hemorrhage: Natural history, prognosis and precursive factors in the Framingham Study
113. Meta-analysis of the ACE gene in ischaemic stroke
114. Genotype and cardiovascular phenotype: Lessons from genetically manipulated animals and diseased humans
115. Angiotensin-converting enzyme gene I/D polymorphism in malignant hypertension
116. Chronological changes in spontaneous intracerebral hematoma - An experimental and clinical study
117. Electron microscopic studies of ruptured arteries in hypertensive intracerebral hemorrhage
118. Small chronic hemorrhages and ischemic lesions in association with spontaneous intracerebral hematomas
119. Three important subgroups of hypertensive persons at greater risk of intracerebral haemorrhage
120. Evidence, from combined segregation and linkage analysis, that a variant of the angiotensin I - Converting enzyme (ACE) gene controls plasma ACE levels
121. Interpretation of results from genetic studies of multifactorial diseases
122. Risk factors and clinical manifestations of pathologically verified lacunar infarctions
123. Vascular damage without hypertension in transgenic rats expressing prorenin exclusively in the liver
124. Lessons from sudden coronary death. A comprehensive morphological classification scheme for atherosclerotic lesions
125. Association and cosegregation of stroke with impaired endothelium-dependent vasorelaxation in stroke-prone, spontaneously hypertensive rats
126. Cerebral amyloid angiopathy without and with cerebral hemorrhages: A comparative histological study
127. Small deep cerebral infarcts associated with occlusive internal carotid artery disease. A hemodynamic phenomenon?
128. Epidemiology of hypertension
129. Pathogenetic similarity of strokes in stroke-prone spontaneously hypertensive rats and humans
130. The angiopathy of subcortical arteriosclerotic encephalopathy (Binswanger's disease): Immunohistochemical studies using markers for components of extracellular matrix, smooth muscle actin and endothelial cells