Elevated production of 20-HETE in the cerebral vasculature contributes to severity of ischemic stroke and oxidative stress in spontaneously hypertensive rats

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 295, Issue 6, 2008, Pages

  Dunn, Kathryn M ^a   Renic, Marija ^a   Flasch, Averia K ^a   Harder, David R ^a   Falck, John ^b   Roman, Richard J ^a  

^a MEDICAL COLLEGE OF WISCONSIN   (United States)

^b UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

20 hydroxyeicosatetraenoic acid; Cytochrome P 450A; Middle cerebral artery occlusion; N hydroxy N (4 butyl 2 methylphenyl) formamidine

Indexed keywords

20 HYDROXYICOSATETRAENOIC ACID; CYTOCHROME P450; CYTOCHROME P450 4A; CYTOCHROME P450 4A1; CYTOCHROME P450 4A8; FORMAMIDINE; HET 0016; MESSENGER RNA; N HYDROXY N' (4 BUTYL 2 METHYLPHENYL)FORMAMIDINE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRAIN ARTERY; BRAIN BLOOD FLOW; BRAIN INFARCTION SIZE; CEREBROVASCULAR ACCIDENT; CONTROLLED STUDY; DISEASE SEVERITY; ENDOTHELIAL DYSFUNCTION; HEMISPHERE; LIQUID CHROMATOGRAPHY; MALE; MIDDLE CEREBRAL ARTERY OCCLUSION; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; RISK FACTOR; SPONTANEOUSLY HYPERTENSIVE RAT; STROKE PRONE SPONTANEOUSLY HYPERTENSIVE RAT; TANDEM MASS SPECTROMETRY; WISTAR KYOTO RAT;

ALKANE 1-MONOOXYGENASE; AMIDINES; ANIMALS; BLOOD PRESSURE; CEREBRAL ARTERIES; CEREBROVASCULAR CIRCULATION; DISEASE MODELS, ANIMAL; ENZYME INHIBITORS; HYDROXYEICOSATETRAENOIC ACIDS; HYPERTENSION; INFARCTION, MIDDLE CEREBRAL ARTERY; ISOENZYMES; MALE; OXIDATIVE STRESS; RATS; RATS, INBRED SHR; RATS, INBRED WKY; REACTIVE OXYGEN SPECIES; SEVERITY OF ILLNESS INDEX; STROKE; TIME FACTORS; UP-REGULATION;

EID: 57349115247     PISSN: 03636135     EISSN: 15221539     Source Type: Journal    
DOI: 10.1152/ajpheart.00512.2008     Document Type: Article

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