Introgression of brown norway CYP4A genes on to the dahl salt-sensitive background restores vascular function in SS-5BN consomic rats

Clinical Science

Volumn 124, Issue 5, 2013, Pages 333-342

  Lukaszewicz, Kathleen M ^a   Falck, John R ^b   Manthati, Vijaya L ^b   Lombard, Julian H ^a  

^a MEDICAL COLLEGE OF WISCONSIN   (United States)

^b UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

20 hydroxyeicosatetraenoic acid (20 HETE); Cytochrome P450 4A hydroxylase (CYP4A); Oxidative stress; Salt sensitive hypertension; Vascular dysfunction

Indexed keywords

20 HYDROXYEICOSA DIENOIC ACID; 20 HYDROXYICOSATETRAENOIC ACID; ACETYLCHOLINE; CYTOCHROME P450 4A; ENDOTHELIAL NITRIC OXIDE SYNTHASE; N METHYL SULFONYL 12,12 DIBROMODODEC 11 ENAMIDE; N(G) NITROARGININE METHYL ESTER; OXIDOREDUCTASE INHIBITOR; SUPEROXIDE DISMUTASE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BROWN NORWAY RAT; CHROMOSOME 5; CHROMOSOME SUBSTITUTION STRAIN; CONTROLLED STUDY; DAHL SALT SENSITIVE RAT; INTROGRESSION; MALE; MIDDLE CEREBRAL ARTERY; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; RAT STRAIN; SS 5BN RAT; UPREGULATION; VASCULAR DISEASE; VASODILATATION;

ALKANE 1-MONOOXYGENASE; ANIMALS; BLOOD PRESSURE; CEREBRAL ARTERIES; ENDOTHELIUM, VASCULAR; HYDROXYEICOSATETRAENOIC ACIDS; MALE; MUSCLE, SMOOTH, VASCULAR; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE III; OXIDATIVE STRESS; RATS; RATS, INBRED BN; RATS, INBRED DAHL; REACTIVE OXYGEN SPECIES; SUPEROXIDE DISMUTASE; VASCULAR DISEASES; VASODILATION;

EID: 84872249355     PISSN: 01435221     EISSN: None     Source Type: Journal    
DOI: 10.1042/CS20120232     Document Type: Article

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