Effect of 20-HETE inhibition on infarct volume and cerebral blood flow after transient middle cerebral artery occlusion

Journal of Cerebral Blood Flow and Metabolism

Volumn 29, Issue 3, 2009, Pages 629-639

  Renic, Marija ^a   Klaus, Judith A ^b   Omura, Tomohiro ^c   Kawashima, Naoya ^c   Onishi, Michihito ^c   Miyata, Noriyuki ^c   Koehler, Raymond C ^b   Harder, David R ^a   Roman, Richard J ^a  

^a MEDICAL COLLEGE OF WISCONSIN   (United States)

^b DEPARTMENT OF PATHOLOGY   (United States)

^c TAISHO PHARMACEUTICAL CO LTD   (Japan)

Author keywords

20 HETE; Cerebral blood flow; Cytochrome P450; Eicosanoids; Ischemic stroke

Indexed keywords

20 HYDROXYEICOSADIENOIC ACID; 20 HYDROXYICOSATETRAENOIC ACID; HET 006; ICOSANOID; N (3 CHLORO 4 MORPHOLIN 4 YL)PHENYL N' HYDROXYIMIDO FORMIDE; N HYDROXY N (4 BUTYL 2 METHYLPHENYL)FORMAMIDINE; TS 011; UNCLASSIFIED DRUG;

ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN BLOOD FLOW; BRAIN INFARCTION SIZE; BRAIN ISCHEMIA; BRAIN TISSUE; CONTINUOUS INFUSION; CONTROLLED STUDY; DRUG EFFICACY; DRUG INHIBITION; HEMISPHERE; MALE; MIDDLE CEREBRAL ARTERY OCCLUSION; NONHUMAN; PRIORITY JOURNAL; RAT; REPERFUSION INJURY;

ANIMALS; BRAIN; CEREBROVASCULAR CIRCULATION; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CYTOCHROME P-450 ENZYME SYSTEM; DISEASE MODELS, ANIMAL; FORMAMIDES; HYDROXYEICOSATETRAENOIC ACIDS; INFARCTION, MIDDLE CEREBRAL ARTERY; LASER-DOPPLER FLOWMETRY; MALE; MASS SPECTROMETRY; MORPHOLINES; NEUROPROTECTIVE AGENTS; RATS; RATS, WISTAR;

EID: 61349178515     PISSN: 0271678X     EISSN: None     Source Type: Journal    
DOI: 10.1038/jcbfm.2008.156     Document Type: Article

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