메뉴 건너뛰기




Volumn 17, Issue 2, 2001, Pages 151-182

Production of transgenic rodents by the microinjection of cloned DNA into fertilized one-cell eggs

Author keywords

Cryopreservation; In vitro fertilization; Microinjection; Oviduct transfer; Superovulation; Transgenic mice; Transgenic rats

Indexed keywords

ANIMAL CELL; CRYOPRESERVATION; FERTILIZATION; FERTILIZATION IN VITRO; GENE FUNCTION; GENE OVEREXPRESSION; GENE SEQUENCE; GENOTYPE; MICROINJECTION; MOLECULAR CLONING; MOUSE; NONHUMAN; PHENOTYPE; RAT; REVIEW; SUPEROVULATION; TRANSGENIC ANIMAL;

EID: 0035020652     PISSN: 10736085     EISSN: None     Source Type: Journal    
DOI: 10.1385/MB:17:2:151     Document Type: Review
Times cited : (13)

References (72)
  • 2
    • 0026848653 scopus 로고
    • Transgenic approaches to modifying cell and tissue function
    • 2. Murphy, D. and Carter, D. (1992) Transgenic approaches to modifying cell and tissue function. Curr. Opin. Cell Biol. 4, 274-279.
    • (1992) Curr. Opin. Cell Biol. , vol.4 , pp. 274-279
    • Murphy, D.1    Carter, D.2
  • 3
    • 0019855228 scopus 로고
    • Introduction of rabbit β-globin gene into the mouse germ line
    • 3. Constantini, F. and Lacy, E. (1981) Introduction of rabbit β-globin gene into the mouse germ line. Nature 294, 92-94.
    • (1981) Nature , vol.294 , pp. 92-94
    • Constantini, F.1    Lacy, E.2
  • 4
    • 0019845629 scopus 로고
    • Microinjection of cloned retroviral genomes into the mouse zygotes: Integration and expression in the animal
    • 4. Harbers, K., Jahner, D., and Jaenisch, R. (1981) Microinjection of cloned retroviral genomes into the mouse zygotes: integration and expression in the animal. Nature 293, 540-542.
    • (1981) Nature , vol.293 , pp. 540-542
    • Harbers, K.1    Jahner, D.2    Jaenisch, R.3
  • 5
    • 0019859395 scopus 로고
    • Somatic expression of herpes thymidine kinase in mice following injection of a fusion gene into eggs
    • 5. Brinster, R. L., Chen, H.Y., and Trumbauer, M. (1981) Somatic expression of herpes thymidine kinase in mice following injection of a fusion gene into eggs. Cell 27, 223-231.
    • (1981) Cell , vol.27 , pp. 223-231
    • Brinster, R.L.1    Chen, H.Y.2    Trumbauer, M.3
  • 6
    • 0020083107 scopus 로고
    • Regulation of metallothioneinthymidine kinase fusion plasmids injected into mouse eggs
    • 6. Brinster, R. L., Chen, H.Y., Warren, R., Sarthy, A., Palmiter, R.D. (1982) Regulation of metallothioneinthymidine kinase fusion plasmids injected into mouse eggs. Nature 296, 39-42.
    • (1982) Nature , vol.296 , pp. 39-42
    • Brinster, R.L.1    Chen, H.Y.2    Warren, R.3    Sarthy, A.4    Palmiter, R.D.5
  • 7
    • 0030237864 scopus 로고    scopus 로고
    • RNA polymerase II: Transcription control
    • 7. Kornberg, R. D. (1996) RNA polymerase II: transcription control. Trends in Biochemical Science 21, 325,326.
    • (1996) Trends in Biochemical Science , vol.21 , pp. 325
    • Kornberg, R.D.1
  • 9
    • 0033542484 scopus 로고    scopus 로고
    • Enhancement of TBP binding by activators and general transcription factors
    • 9. Li, X.-Y., Virbasius, A., Zhu, X., and Green, M. R. (1999) Enhancement of TBP binding by activators and general transcription factors. Nature 399, 605-609.
    • (1999) Nature , vol.399 , pp. 605-609
    • Li, X.-Y.1    Virbasius, A.2    Zhu, X.3    Green, M.R.4
  • 10
    • 0030249381 scopus 로고    scopus 로고
    • The role of general initiation factor in transcription by RNA polymerase II
    • 10. Roeder, R. G. (1996) The role of general initiation factor in transcription by RNA polymerase II, Trends in Biochemical Science 21, 327-334.
    • (1996) Trends in Biochemical Science , vol.21 , pp. 327-334
    • Roeder, R.G.1
  • 12
    • 0030249382 scopus 로고    scopus 로고
    • TAFs mediate transcriptional activation and promoter selectivity
    • 12. Verrijzer, C. P. and Tijan, R. (1996) TAFs mediate transcriptional activation and promoter selectivity. Trends in Biochemical Sciences 21, 338-342.
    • (1996) Trends in Biochemical Sciences , vol.21 , pp. 338-342
    • Verrijzer, C.P.1    Tijan, R.2
  • 13
    • 0020611791 scopus 로고
    • A lymphocytes-specific cellular enhancer is located downstream of the joining region in immunoglobulin heavy chain genes
    • 13. Banerji, J., Olson, L., and Schaffner, W. (1983) A lymphocytes-specific cellular enhancer is located downstream of the joining region in immunoglobulin heavy chain genes. Cell 33, 729-740.
    • (1983) Cell , vol.33 , pp. 729-740
    • Banerji, J.1    Olson, L.2    Schaffner, W.3
  • 14
    • 0020561224 scopus 로고
    • Immunoglobulin gene transcription is activated by downstream elements
    • 14. Queen, C. and Baltimore, D. (1983) Immunoglobulin gene transcription is activated by downstream elements. Cell 33, 741-748.
    • (1983) Cell , vol.33 , pp. 741-748
    • Queen, C.1    Baltimore, D.2
  • 15
    • 0020567861 scopus 로고
    • A tissue-specific transcription enhancer element is located in the major intron of a rearranged immunoglobulin heavy chain gene
    • 15. Gillies, S. D., Morrison, S.L., Oi, V.T., and Tonegawa, S. (1983) A tissue-specific transcription enhancer element is located in the major intron of a rearranged immunoglobulin heavy chain gene. Cell 33, 717-728.
    • (1983) Cell , vol.33 , pp. 717-728
    • Gillies, S.D.1    Morrison, S.L.2    Oi, V.T.3    Tonegawa, S.4
  • 16
    • 0021071029 scopus 로고
    • Cell-specific expression controlled by the 5'-flanking region of insulin and chymotrypsin
    • 16. Walker, M. D., Edlund, T., Boulet, A. M., and Rutter, W. J. (1983) Cell-specific expression controlled by the 5'-flanking region of insulin and chymotrypsin. Nature 306, 557-561.
    • (1983) Nature , vol.306 , pp. 557-561
    • Walker, M.D.1    Edlund, T.2    Boulet, A.M.3    Rutter, W.J.4
  • 17
    • 0021961473 scopus 로고
    • Specific expression of an elastase-human growth hormone fusion gene in pancreatic acinar cells of transgenic mice
    • 17. Ornitz, D. M., Palmiter, R. D., Hammer, R. E., Brinster, R. L., Swift, G. H., and MacDonald, R. J. (1985) Specific expression of an elastase-human growth hormone fusion gene in pancreatic acinar cells of transgenic mice. Nature 313, 600-602.
    • (1985) Nature , vol.313 , pp. 600-602
    • Ornitz, D.M.1    Palmiter, R.D.2    Hammer, R.E.3    Brinster, R.L.4    Swift, G.H.5    MacDonald, R.J.6
  • 18
    • 0024336488 scopus 로고
    • Glucocorticoid regulation of human growth hormone expression in transgenic mice amnd transiently transfected cells
    • 18. Selden, R. F., Yun, J. S., Moore, D. D., Rowe, M. E., Malia, M. A., Wagner, T. E., et al. (1989) Glucocorticoid regulation of human growth hormone expression in transgenic mice amnd transiently transfected cells. J. Endocrinol. 122, 49-60.
    • (1989) J. Endocrinol. , vol.122 , pp. 49-60
    • Selden, R.F.1    Yun, J.S.2    Moore, D.D.3    Rowe, M.E.4    Malia, M.A.5    Wagner, T.E.6
  • 19
    • 0028199875 scopus 로고
    • DNA regulatory sequences of the rat tyrosine hydroxylase gene direct correct catecholoaminergic cell-type specificity of a human growth hormone reporter in the CNS of transgenic mice causing a dwarf phenotype
    • 19. Banerjee, S. A., Roffler-Tarlov, S., Szabo, M., Frohman, L., and Chikaraishi, D.M. (1994) DNA regulatory sequences of the rat tyrosine hydroxylase gene direct correct catecholoaminergic cell-type specificity of a human growth hormone reporter in the CNS of transgenic mice causing a dwarf phenotype. Mol. Brain Res. 24, 89-106.
    • (1994) Mol. Brain Res. , vol.24 , pp. 89-106
    • Banerjee, S.A.1    Roffler-Tarlov, S.2    Szabo, M.3    Frohman, L.4    Chikaraishi, D.M.5
  • 20
    • 0021933180 scopus 로고
    • Novel developmental specificity in the nervous system of transgenic animals expressing growth hormone fusion genes
    • 20. Swanson, L. W., Simmons, D. M., Arriza, J., Hammer, R., Brinster, R., Rosenfeld, M. G., et al. (1985) Novel developmental specificity in the nervous system of transgenic animals expressing growth hormone fusion genes. Nature 317, 363-366.
    • (1985) Nature , vol.317 , pp. 363-366
    • Swanson, L.W.1    Simmons, D.M.2    Arriza, J.3    Hammer, R.4    Brinster, R.5    Rosenfeld, M.G.6
  • 21
    • 0020511078 scopus 로고
    • A foreign β-globin gene in transgenic mice: Integration at abnormal chromosomal positions and expression in inappropriate tissues
    • 21. Lacy, E., Roberts, S., Evans, E. P., Burtenshaw, M. D., and Costantini, F. D. (1983) A foreign β-globin gene in transgenic mice: Integration at abnormal chromosomal positions and expression in inappropriate tissues. Cell 34, 343-358.
    • (1983) Cell , vol.34 , pp. 343-358
    • Lacy, E.1    Roberts, S.2    Evans, E.P.3    Burtenshaw, M.D.4    Costantini, F.D.5
  • 22
    • 0025017002 scopus 로고
    • Expression of a foreign gene in a line of transgenic mice is modulated by chromosomal position effect
    • 22. Al-Shawi, R., Kinnaird, J., Burke, J., and Bishop, J. O. (1990) Expression of a foreign gene in a line of transgenic mice is modulated by chromosomal position effect. Mol. Cell. Biol. 10, 1192-1198.
    • (1990) Mol. Cell. Biol. , vol.10 , pp. 1192-1198
    • Al-Shawi, R.1    Kinnaird, J.2    Burke, J.3    Bishop, J.O.4
  • 23
    • 0028027805 scopus 로고
    • Chromosomal position effect in chicken lysozyme gene transgenic mice are correlated with supression of DNase I hypersensitive site formation
    • 23. Huber, M. C, Bosch, F. X., Sippel, A. E., and Bonifer, C. (1994) Chromosomal position effect in chicken lysozyme gene transgenic mice are correlated with supression of DNase I hypersensitive site formation. Nucleic Acids Res. 22, 4195-4201.
    • (1994) Nucleic Acids Res. , vol.22 , pp. 4195-4201
    • Huber, M.C.1    Bosch, F.X.2    Sippel, A.E.3    Bonifer, C.4
  • 24
    • 0023663887 scopus 로고
    • Position-independent, high-level expression of human β-globin gene in transgenic mice
    • 24. Grosveld, F., van Assendelft, G. B., Greaves, D. R., and Kollias, G. (1987) Position-independent, high-level expression of human β-globin gene in transgenic mice. Cell 51, 975-985.
    • (1987) Cell , vol.51 , pp. 975-985
    • Grosveld, F.1    Van Assendelft, G.B.2    Greaves, D.R.3    Kollias, G.4
  • 26
  • 27
    • 0024948946 scopus 로고
    • A nuclear DNA attachment element mediates elevated and position-independent gene activity
    • 27. Stief, A., Winter, D. M., Strätling, W. H., and Sippel, A. E. (1989) A nuclear DNA attachment element mediates elevated and position-independent gene activity. Nature 341, 343-345.
    • (1989) Nature , vol.341 , pp. 343-345
    • Stief, A.1    Winter, D.M.2    Strätling, W.H.3    Sippel, A.E.4
  • 28
    • 0024993211 scopus 로고
    • A major positive regulatory region located far upstream of the human α-globin gene locus
    • 28. Higgs, D. R., Wood, W. G., Jarman, A. P., Sharpe, J., Lida, J., Pretorius, I.-M.,et al. (1990) A major positive regulatory region located far upstream of the human α-globin gene locus. Genes and Dev. 4, 1588-1601.
    • (1990) Genes and Dev. , vol.4 , pp. 1588-1601
    • Higgs, D.R.1    Wood, W.G.2    Jarman, A.P.3    Sharpe, J.4    Lida, J.5    Pretorius, I.-M.6
  • 29
    • 0028806064 scopus 로고
    • The human growth hormone gene is regulated by multicomponent locus control region
    • 29. Jones, B. K., Monks, B. R., Liebhaber, S. A., and Cooke, N. E, (1995) The human growth hormone gene is regulated by multicomponent locus control region. Mol. Cell. Biol. 15, 7010-7021.
    • (1995) Mol. Cell. Biol. , vol.15 , pp. 7010-7021
    • Jones, B.K.1    Monks, B.R.2    Liebhaber, S.A.3    Cooke, N.E.4
  • 30
    • 0025369610 scopus 로고
    • DNase I hypersensitive sites 1, 2 and 3 of the human β-globin dominant control region direct position-independent expression
    • 30. Fraser, P., Hurst, J., Collis, P., and Grosveld, F. (1990) DNase I hypersensitive sites 1, 2 and 3 of the human β-globin dominant control region direct position-independent expression. Nucleic Acids Res. 18, 3503-3508.
    • (1990) Nucleic Acids Res. , vol.18 , pp. 3503-3508
    • Fraser, P.1    Hurst, J.2    Collis, P.3    Grosveld, F.4
  • 31
    • 0027254748 scopus 로고
    • A 5' element of the chicken β-globin domain serves as an insulator in human erythroid cells and protects against position effect in drosophila
    • 31. Chung, J. H., Whiteley, M., and Felsenfeld, G. (1993) A 5' element of the chicken β-globin domain serves as an insulator in human erythroid cells and protects against position effect in drosophila. Cell 74, 505-514.
    • (1993) Cell , vol.74 , pp. 505-514
    • Chung, J.H.1    Whiteley, M.2    Felsenfeld, G.3
  • 32
    • 0028795722 scopus 로고
    • Dissecting a locus control region: Facilitation of enhancer function by extended enhancer-flanking sequeces
    • 32. Aronow, B. J., Ebert, C. A., Valerius, M. T., Potter, S. S., Wiginton, D. A., Witte, D. P., et al. (1995) Dissecting a locus control region: facilitation of enhancer function by extended enhancer-flanking sequeces, Mol. Cell. Biol. 15, 1123-1135.
    • (1995) Mol. Cell. Biol. , vol.15 , pp. 1123-1135
    • Aronow, B.J.1    Ebert, C.A.2    Valerius, M.T.3    Potter, S.S.4    Wiginton, D.A.5    Witte, D.P.6
  • 33
    • 0025107556 scopus 로고
    • A deletion of the human β-globin locus activation region causes a major alteration in chromatin structure and replication across the entire β-globin locus
    • 33. Forrester, W. C., Epner, E., Driscoll, M.C., Enver, T., Brice, M., Papayannopoulou, T., et al. (1990) A deletion of the human β-globin locus activation region causes a major alteration in chromatin structure and replication across the entire β-globin locus. Genes and Dev. 4, 1637-1649.
    • (1990) Genes and Dev. , vol.4 , pp. 1637-1649
    • Forrester, W.C.1    Epner, E.2    Driscoll, M.C.3    Enver, T.4    Brice, M.5    Papayannopoulou, T.6
  • 34
    • 0030726908 scopus 로고    scopus 로고
    • Locus control regions: Overcoming heterochromatin-induced gene inactivation in mammals
    • 34. Kioussis, D. and Festenstein, R. (1997) Locus control regions: overcoming heterochromatin-induced gene inactivation in mammals. Current Biology 7, 614-619.
    • (1997) Current Biology , vol.7 , pp. 614-619
    • Kioussis, D.1    Festenstein, R.2
  • 35
  • 36
    • 0030989229 scopus 로고    scopus 로고
    • Mechanism and regulation of transcriptional elongation and termination by RNA polymerase II
    • 36. Shilatifard, A., Conaway, J. W., and Conaway, R. C. (1997) Mechanism and regulation of transcriptional elongation and termination by RNA polymerase II. Cur. Op. Genetics and Development 7, 199-204.
    • (1997) Cur. Op. Genetics and Development , vol.7 , pp. 199-204
    • Shilatifard, A.1    Conaway, J.W.2    Conaway, R.C.3
  • 37
    • 0028095580 scopus 로고
    • Mechanisms of mRNA degradation in eukaryotes
    • 37. Decker, C. J. and Parker, R. (1994) Mechanisms of mRNA degradation in eukaryotes. Trends in Biochemical Sciences 19, 336-340.
    • (1994) Trends in Biochemical Sciences , vol.19 , pp. 336-340
    • Decker, C.J.1    Parker, R.2
  • 38
    • 0027279421 scopus 로고
    • Messenger RNA degradation in eukaryotes
    • 38. Sachs, A. B. (1993) Messenger RNA degradation in eukaryotes. Cell 74, 413-421.
    • (1993) Cell , vol.74 , pp. 413-421
    • Sachs, A.B.1
  • 39
    • 0022552131 scopus 로고
    • Point mutations define a sequence flanking the AUG initiator codon that modulates translation by eukaryotic ribosomes
    • 39. Kozak, M. (1985) Point mutations define a sequence flanking the AUG initiator codon that modulates translation by eukaryotic ribosomes. Cell 44, 283-292.
    • (1985) Cell , vol.44 , pp. 283-292
    • Kozak, M.1
  • 40
    • 0020470466 scopus 로고
    • Dramatic growth of mice that develop from eggs microinjected with metallothionein-growth hormone fusion genes
    • 40. Palmiter, R. D., Brinster, R. L., Hammer, R. E., Trumbauer, M. E., Rosenfeld, M. G., Birnberg, N. C., et al. (1982) Dramatic growth of mice that develop from eggs microinjected with metallothionein-growth hormone fusion genes. Nature 300, 611-615.
    • (1982) Nature , vol.300 , pp. 611-615
    • Palmiter, R.D.1    Brinster, R.L.2    Hammer, R.E.3    Trumbauer, M.E.4    Rosenfeld, M.G.5    Birnberg, N.C.6
  • 41
    • 0023751235 scopus 로고
    • Tissue-specific expression and dietary regulation of a chimeric phosphoenolpyruvate carboxykinase/ bovine growth hormone gene in transgenic mice
    • 41. McGrane, M. M., de Vente, J., Yun, J., Bloom, J., Park, E., Wynshaw-Boris, A., et al. (1988) Tissue-specific expression and dietary regulation of a chimeric phosphoenolpyruvate carboxykinase/ bovine growth hormone gene in transgenic mice. J. Biol. Chem 263, 11,443-11,451.
    • (1988) J. Biol. Chem , vol.263 , pp. 11443-11451
    • McGrane, M.M.1    De Vente, J.2    Yun, J.3    Bloom, J.4    Park, E.5    Wynshaw-Boris, A.6
  • 43
    • 0024424678 scopus 로고
    • A dominant phenocopy of hypopituitarism in transgenic mice resulting from central nervous system synthesis of human growth hormone
    • 43. Hollingshead, P. G., Martin, L., Pitts, S.L., and Stewart, T.A. (1989) A dominant phenocopy of hypopituitarism in transgenic mice resulting from central nervous system synthesis of human growth hormone. Endocrinol. 125, 1556-1564.
    • (1989) Endocrinol. , vol.125 , pp. 1556-1564
    • Hollingshead, P.G.1    Martin, L.2    Pitts, S.L.3    Stewart, T.A.4
  • 44
    • 0026055409 scopus 로고
    • Expression of a retinoic acid response element-hsplacZ transgene defines specific domains of transcriptional activity during mouse embryogenesis
    • 44. Rossant, J., Zirngibl, R., Cado, D., Shago, M., and Giguére, V. (1991) Expression of a retinoic acid response element-hsplacZ transgene defines specific domains of transcriptional activity during mouse embryogenesis. Genes and Dev. 5, 1333-1344.
    • (1991) Genes and Dev. , vol.5 , pp. 1333-1344
    • Rossant, J.1    Zirngibl, R.2    Cado, D.3    Shago, M.4    Giguére, V.5
  • 45
    • 0026585377 scopus 로고
    • Fos-lacZ transgenic mice: Mapping sites of gene induction in the central nervous system
    • 45. Smeyne, R. J., Schilling, K., Robertson, L., Luk, D., Oberdick, J., Curran, T., et al. (1992) Fos-lacZ transgenic mice: Mapping sites of gene induction in the central nervous system. Neuron 8, 13-23.
    • (1992) Neuron , vol.8 , pp. 13-23
    • Smeyne, R.J.1    Schilling, K.2    Robertson, L.3    Luk, D.4    Oberdick, J.5    Curran, T.6
  • 46
    • 0004922312 scopus 로고
    • Glucocorticoid regulation of mouse mammary tumor virus sequences in transgenic mice
    • 46. Ross, S. R., Solter, D. (1985) Glucocorticoid regulation of mouse mammary tumor virus sequences in transgenic mice. Proc. Natl. Acad. Sci. USA 83, 5880-5884.
    • (1985) Proc. Natl. Acad. Sci. USA , vol.83 , pp. 5880-5884
    • Ross, S.R.1    Solter, D.2
  • 47
    • 0022758906 scopus 로고
    • Studies on the expression of an H-2K/human growth hormone fusion gene in giant transgenic mice
    • 47. Morello, D., Moore, G., Salmon, A. M., Yaniv, M., and Babinet, C. (1986) Studies on the expression of an H-2K/human growth hormone fusion gene in giant transgenic mice. EMBO J. 5, 1877-1883.
    • (1986) EMBO J. , vol.5 , pp. 1877-1883
    • Morello, D.1    Moore, G.2    Salmon, A.M.3    Yaniv, M.4    Babinet, C.5
  • 48
    • 0025322555 scopus 로고
    • Expression of a mutated bovine growth hormone gene suppresses growth of transgenic mice
    • 48. Chen, W. Y., Wight, D. C., Wagner, T. E., and Kopchick, J. J. (1990) Expression of a mutated bovine growth hormone gene suppresses growth of transgenic mice. Proc. Natl. Acad. Sci. USA 87, 5061-5065.
    • (1990) Proc. Natl. Acad. Sci. USA , vol.87 , pp. 5061-5065
    • Chen, W.Y.1    Wight, D.C.2    Wagner, T.E.3    Kopchick, J.J.4
  • 49
    • 0033616721 scopus 로고    scopus 로고
    • Blood pressure reduction and diabetes insipidus in transgenic rats deficient in brain angiotensinogen
    • 49. Schinke, M., Baltatu, O., Bohm, M., Peters, J., Rascher, W., Bricca, G., et al. (1999) Blood pressure reduction and diabetes insipidus in transgenic rats deficient in brain angiotensinogen. Proc. Natl. Acad. Sci. USA 96, 3975-3980.
    • (1999) Proc. Natl. Acad. Sci. USA , vol.96 , pp. 3975-3980
    • Schinke, M.1    Baltatu, O.2    Bohm, M.3    Peters, J.4    Rascher, W.5    Bricca, G.6
  • 50
    • 0029151066 scopus 로고
    • Neuroanti-bodies: Ectopic expression of a recombinant anti-substance P antibody in the central nervous system of transgenic mice
    • 50. Piccioli, P., Di Luzio, A., Amann, R., Schuligoi, R., Surani, M. A., Donnerer, J., et al. (1995) Neuroanti-bodies: ectopic expression of a recombinant anti-substance P antibody in the central nervous system of transgenic mice. Neuron 15, 373-384.
    • (1995) Neuron , vol.15 , pp. 373-384
    • Piccioli, P.1    Di Luzio, A.2    Amann, R.3    Schuligoi, R.4    Surani, M.A.5    Donnerer, J.6
  • 51
    • 0023989832 scopus 로고
    • Dwarf mice produced by genetic ablation of growth hormone expressing cells
    • 51. Behringer, R. R. L. S., Mathews, R. D., Palmiter, R. D., and Brinster, R. L. (1988) Dwarf mice produced by genetic ablation of growth hormone expressing cells. Genes and Dev. 2, 453-461.
    • (1988) Genes and Dev. , vol.2 , pp. 453-461
    • Behringer, R.R.L.S.1    Mathews, R.D.2    Palmiter, R.D.3    Brinster, R.L.4
  • 52
    • 0025853062 scopus 로고
    • Somatotroph hypoplasia and dwarfism in transgenic mice expressing a non-phosphorylatable CREB mutant
    • 52. Struthers, R. S., Vale, W. W., Arias, C., Sawchenko, P. E., and Montminy, M. R. (1991) Somatotroph hypoplasia and dwarfism in transgenic mice expressing a non-phosphorylatable CREB mutant. Nature 350, 622-624.
    • (1991) Nature , vol.350 , pp. 622-624
    • Struthers, R.S.1    Vale, W.W.2    Arias, C.3    Sawchenko, P.E.4    Montminy, M.R.5
  • 53
    • 0026062347 scopus 로고
    • Pituitary hyperplasia and giantism in mice caused by cholera toxin transgene
    • 53. Burton, F. H., Hasel, K. W., Bloom, F. E., and Sutcliffe, J. G. (1991) Pituitary hyperplasia and giantism in mice caused by cholera toxin transgene. Nature 350, 74-77.
    • (1991) Nature , vol.350 , pp. 74-77
    • Burton, F.H.1    Hasel, K.W.2    Bloom, F.E.3    Sutcliffe, J.G.4
  • 54
    • 0029783602 scopus 로고    scopus 로고
    • Dominant dwarfism in transgenic rats by targeting human growth hormone (GH) expression to hypothalamic GH-releasing factor neurons
    • 54. Flavell, D. M., Wells, T., Wells, S. E., Carmignac, D. F., Thomas, G. B., and Robinson, I. C. (1996) Dominant dwarfism in transgenic rats by targeting human growth hormone (GH) expression to hypothalamic GH-releasing factor neurons. EMBO J. 15, 3871-3879.
    • (1996) EMBO J. , vol.15 , pp. 3871-3879
    • Flavell, D.M.1    Wells, T.2    Wells, S.E.3    Carmignac, D.F.4    Thomas, G.B.5    Robinson, I.C.6
  • 55
    • 0028004573 scopus 로고
    • Cell specific expression of a vasopressin transgene in rats
    • 55. Zeng, Q., Carter, D. A., and Murphy, D. (1994) Cell specific expression of a vasopressin transgene in rats. J. Neuroendocrinol. 6, 469-477.
    • (1994) J. Neuroendocrinol. , vol.6 , pp. 469-477
    • Zeng, Q.1    Carter, D.A.2    Murphy, D.3
  • 57
    • 0001305936 scopus 로고
    • Factors affecting the efficiency of introducing foreign DNA into mice by microinjecting eggs
    • 57. Brinster, R. L., Chen, H. Y., Trunbauer, M. E., Yagle, M. K., and Palmiter, R. D. (1985) Factors affecting the efficiency of introducing foreign DNA into mice by microinjecting eggs. Proc. Natl. Acad. Sci. USA 82, 4438-4442.
    • (1985) Proc. Natl. Acad. Sci. USA , vol.82 , pp. 4438-4442
    • Brinster, R.L.1    Chen, H.Y.2    Trunbauer, M.E.3    Yagle, M.K.4    Palmiter, R.D.5
  • 58
    • 0025239301 scopus 로고
    • Fulminant hypertension in transgenic rats harbouring the mouse Ren-2 gene
    • 58. Mullins, J. J., Peters, J., and Ganten, D. (1990) Fulminant hypertension in transgenic rats harbouring the mouse Ren-2 gene. Nature 344, 541-544.
    • (1990) Nature , vol.344 , pp. 541-544
    • Mullins, J.J.1    Peters, J.2    Ganten, D.3
  • 60
    • 0021911408 scopus 로고
    • Specific expression of a foreign B-globin gene in erythroid cells in transgenic mice
    • 60. Chada, K., Magram, J., Raphael, K., Radice, G., Lacy, E., and Constantini, F. (1985) Specific expression of a foreign B-globin gene in erythroid cells in transgenic mice. Nature 314, 377-380.
    • (1985) Nature , vol.314 , pp. 377-380
    • Chada, K.1    Magram, J.2    Raphael, K.3    Radice, G.4    Lacy, E.5    Constantini, F.6
  • 61
    • 0025259637 scopus 로고
    • The promoter that drives transgene expression in cerebellar Purkinje and retinal bipolar neurons
    • 61. Oberdick, J., Smeyne, R. J., Mann, J. R., Zackson, S., and Morgan, J. I. (1990) The promoter that drives transgene expression in cerebellar Purkinje and retinal bipolar neurons. Science 248, 223-236.
    • (1990) Science , vol.248 , pp. 223-236
    • Oberdick, J.1    Smeyne, R.J.2    Mann, J.R.3    Zackson, S.4    Morgan, J.I.5
  • 64
    • 0027464687 scopus 로고
    • A yeast artificial chromosome covering the tyrosinase gene confers copy number-dependent expression in transgenic mice
    • 64. Schedl, A., Montoliu, L., Kelsey, G., and Schutz, G. (1993) A yeast artificial chromosome covering the tyrosinase gene confers copy number-dependent expression in transgenic mice. Nature 362, 258-261.
    • (1993) Nature , vol.362 , pp. 258-261
    • Schedl, A.1    Montoliu, L.2    Kelsey, G.3    Schutz, G.4
  • 65
    • 0021933180 scopus 로고
    • Novel developmental specificity in the nervous system of transgenic animal expressing growth hormone fusion gene
    • 65. Swanson, L. W., Simmons, D. M., Azzira, J., Hammer, R., and Brinster, R. (1985) Novel developmental specificity in the nervous system of transgenic animal expressing growth hormone fusion gene. Nature 317, 363-366.
    • (1985) Nature , vol.317 , pp. 363-366
    • Swanson, L.W.1    Simmons, D.M.2    Azzira, J.3    Hammer, R.4    Brinster, R.5
  • 66
    • 0000822783 scopus 로고
    • Preparative and analytical purification of DNA from agarose
    • 66. Vogelstein, B. and Gillespie, D. (1979) Preparative and analytical purification of DNA from agarose. Proc. Natl. Acad. Sci. USA 82, 615-619.
    • (1979) Proc. Natl. Acad. Sci. USA , vol.82 , pp. 615-619
    • Vogelstein, B.1    Gillespie, D.2
  • 67
    • 0019855228 scopus 로고
    • Introduction of a rabbit B-globin gene into the mouse germ line
    • 67. Constantini, F. and Lacy, E. (1981) Introduction of a rabbit B-globin gene into the mouse germ line. Nature 294, 92-94.
    • (1981) Nature , vol.294 , pp. 92-94
    • Constantini, F.1    Lacy, E.2
  • 70
    • 44949275771 scopus 로고
    • Cryopreservation of transgenic mice
    • 70. Pomeroy, K. O. (1991) Cryopreservation of transgenic mice. GATA 8, 95-101.
    • (1991) GATA , vol.8 , pp. 95-101
    • Pomeroy, K.O.1
  • 71
    • 0025214194 scopus 로고
    • A simple method for mouse embryo cryopreservation in a low toxicity vitrification solution, without appreciable loss of viabilty
    • 71. Kasai, M., Komi, J. H., Takakomo, A., Tsudura, H., Sakurai, T., and Machada, T. (1990) A simple method for mouse embryo cryopreservation in a low toxicity vitrification solution, without appreciable loss of viabilty. J. Reprod. Fertil. 89, 91-97.
    • (1990) J. Reprod. Fertil. , vol.89 , pp. 91-97
    • Kasai, M.1    Komi, J.H.2    Takakomo, A.3    Tsudura, H.4    Sakurai, T.5    Machada, T.6
  • 72
    • 0023884178 scopus 로고
    • Cryopreservation of rat blastocysts by vitrification
    • 72. Kono, T., Suzuki, O., and Tsunoda, Y. (1988) Cryopreservation of rat blastocysts by vitrification. Cryobiology 25, 170-173.
    • (1988) Cryobiology , vol.25 , pp. 170-173
    • Kono, T.1    Suzuki, O.2    Tsunoda, Y.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.