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Volumn 61, Issue 3, 2015, Pages 915-929

Astrocyte elevated gene-1 and c-Myc cooperate to promote hepatocarcinogenesis in mice

Author keywords

[No Author keywords available]

Indexed keywords

ALBUMIN; BETA CATENIN; CLAUDIN 1; DIETHYLNITROSAMINE; EPIDERMAL GROWTH FACTOR RECEPTOR; INHIBITOR OF APOPTOSIS PROTEIN 1; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; NERVE CELL ADHESION MOLECULE; OSTEONECTIN; PROTEIN BCL 2; PROTEIN KINASE P60; PROTEIN ZO1; SCATTER FACTOR RECEPTOR; STAT3 PROTEIN; SURVIVIN; TRANSCRIPTION FACTOR SLUG; TRANSCRIPTION FACTOR SNAIL; TRANSCRIPTION FACTOR ZEB1; TRANSFORMING GROWTH FACTOR BETA; UNTRANSLATED RNA; UVOMORULIN; VIMENTIN; X LINKED INHIBITOR OF APOPTOSIS; ALBUMINOID; MEMBRANE PROTEIN; MTDH PROTEIN, MOUSE; MYC PROTEIN; MYC PROTEIN, MOUSE;

EID: 84923402016     PISSN: 02709139     EISSN: 15273350     Source Type: Journal    
DOI: 10.1002/hep.27339     Document Type: Article
Times cited : (37)

References (45)
  • 1
    • 84880927185 scopus 로고    scopus 로고
    • AEG-1/MTDH/LYRIC: clinical significance
    • Sarkar D, Fisher PB. AEG-1/MTDH/LYRIC: clinical significance. Adv Cancer Res 2013;120:39-74.
    • (2013) Adv Cancer Res , vol.120 , pp. 39-74
    • Sarkar, D.1    Fisher, P.B.2
  • 2
    • 65649143486 scopus 로고    scopus 로고
    • Astrocyte elevated gene-1 regulates hepatocellular carcinoma development and progression
    • Yoo BK, Emdad L, Su ZZ, Villanueva A, Chiang DY, Mukhopadhyay ND, et al. Astrocyte elevated gene-1 regulates hepatocellular carcinoma development and progression. J Clin Invest 2009;119:465-477.
    • (2009) J Clin Invest , vol.119 , pp. 465-477
    • Yoo, B.K.1    Emdad, L.2    Su, Z.Z.3    Villanueva, A.4    Chiang, D.Y.5    Mukhopadhyay, N.D.6
  • 3
    • 82555173154 scopus 로고    scopus 로고
    • Metadherin promotes hepatocellular carcinoma metastasis through induction of epithelial-mesenchymal transition
    • Zhu K, Dai Z, Pan Q, Wang Z, Yang GH, Yu L, et al. Metadherin promotes hepatocellular carcinoma metastasis through induction of epithelial-mesenchymal transition. Clin Cancer Res 2011;17:7294-7302.
    • (2011) Clin Cancer Res , vol.17 , pp. 7294-7302
    • Zhu, K.1    Dai, Z.2    Pan, Q.3    Wang, Z.4    Yang, G.H.5    Yu, L.6
  • 4
    • 84860718788 scopus 로고    scopus 로고
    • Prognostic significance of metadherin overexpression in hepatitis B virus-related hepatocellular carcinoma
    • Gong Z, Liu W, You N, Wang T, Wang X, Lu P, et al. Prognostic significance of metadherin overexpression in hepatitis B virus-related hepatocellular carcinoma. Oncol Rep 2012;27:2073-2079.
    • (2012) Oncol Rep , vol.27 , pp. 2073-2079
    • Gong, Z.1    Liu, W.2    You, N.3    Wang, T.4    Wang, X.5    Lu, P.6
  • 5
    • 77951049689 scopus 로고    scopus 로고
    • Molecular mechanism of chemoresistance by astrocyte elevated gene-1 (AEG-1)
    • Yoo BK, Chen D, Su ZZ, Gredler R, Yoo J, Shah K, et al. Molecular mechanism of chemoresistance by astrocyte elevated gene-1 (AEG-1). Cancer Res 2010;70:3249-3258.
    • (2010) Cancer Res , vol.70 , pp. 3249-3258
    • Yoo, B.K.1    Chen, D.2    Su, Z.Z.3    Gredler, R.4    Yoo, J.5    Shah, K.6
  • 7
    • 79955096969 scopus 로고    scopus 로고
    • Increased RNA-induced silencing complex (RISC) activity contributes to hepatocelllular carcinoma
    • Yoo BK, Santhekadur PK, Gredler R, Chen D, Emdad L, Bhutia SK, et al. Increased RNA-induced silencing complex (RISC) activity contributes to hepatocelllular carcinoma. Hepatology 2011;53:1538-1548.
    • (2011) Hepatology , vol.53 , pp. 1538-1548
    • Yoo, B.K.1    Santhekadur, P.K.2    Gredler, R.3    Chen, D.4    Emdad, L.5    Bhutia, S.K.6
  • 8
    • 84868257532 scopus 로고    scopus 로고
    • Astrocyte elevated gene-1 (AEG-1) promotes hepatocarcinogenesis: novel insights from a mouse model
    • Srivastava J, Siddiq A, Emdad L, Santhekadur P, Chen D, Gredler R, et al. Astrocyte elevated gene-1 (AEG-1) promotes hepatocarcinogenesis: novel insights from a mouse model. Hepatology 2012;56:1782-1791.
    • (2012) Hepatology , vol.56 , pp. 1782-1791
    • Srivastava, J.1    Siddiq, A.2    Emdad, L.3    Santhekadur, P.4    Chen, D.5    Gredler, R.6
  • 9
    • 84863804699 scopus 로고    scopus 로고
    • MicroRNA-375 targets AEG-1 in hepatocellular carcinoma and suppresses liver cancer cell growth in vitro and in vivo
    • He XX, Chang Y, Meng FY, Wang MY, Xie QH, Tang F, et al. MicroRNA-375 targets AEG-1 in hepatocellular carcinoma and suppresses liver cancer cell growth in vitro and in vivo. Oncogene 2012;31:3357-3369.
    • (2012) Oncogene , vol.31 , pp. 3357-3369
    • He, X.X.1    Chang, Y.2    Meng, F.Y.3    Wang, M.Y.4    Xie, Q.H.5    Tang, F.6
  • 10
    • 65649106197 scopus 로고    scopus 로고
    • LYRIC/AEG-1 is targeted to different subcellular compartments by ubiquitinylation and intrinsic nuclear localization signals
    • Thirkettle HJ, Girling J, Warren AY, Mills IG, Sahadevan K, Leung H, et al. LYRIC/AEG-1 is targeted to different subcellular compartments by ubiquitinylation and intrinsic nuclear localization signals. Clin Cancer Res 2009;15:3003-3013.
    • (2009) Clin Cancer Res , vol.15 , pp. 3003-3013
    • Thirkettle, H.J.1    Girling, J.2    Warren, A.Y.3    Mills, I.G.4    Sahadevan, K.5    Leung, H.6
  • 11
    • 84055212101 scopus 로고    scopus 로고
    • Significance of dysregulated metadherin and microRNA-375 in head and neck cancer
    • Hui AB, Bruce JP, Alajez NM, Shi W, Yue S, Perez-Ordonez B, et al. Significance of dysregulated metadherin and microRNA-375 in head and neck cancer. Clin Cancer Res 2011;17:7539-7550.
    • (2011) Clin Cancer Res , vol.17 , pp. 7539-7550
    • Hui, A.B.1    Bruce, J.P.2    Alajez, N.M.3    Shi, W.4    Yue, S.5    Perez-Ordonez, B.6
  • 12
    • 84867572569 scopus 로고    scopus 로고
    • MiR-136 promotes apoptosis of glioma cells by targeting AEG-1 and Bcl-2
    • Yang Y, Wu J, Guan H, Cai J, Fang L, Li J, Li M. MiR-136 promotes apoptosis of glioma cells by targeting AEG-1 and Bcl-2. FEBS Lett 2012;586:3608-3612.
    • (2012) FEBS Lett , vol.586 , pp. 3608-3612
    • Yang, Y.1    Wu, J.2    Guan, H.3    Cai, J.4    Fang, L.5    Li, J.6    Li, M.7
  • 13
    • 79952118835 scopus 로고    scopus 로고
    • Pathologically decreased miR-26a antagonizes apoptosis and facilitates carcinogenesis by targeting MTDH and EZH2 in breast cancer
    • Zhang B, Liu XX, He JR, Zhou CX, Guo M, He M, et al. Pathologically decreased miR-26a antagonizes apoptosis and facilitates carcinogenesis by targeting MTDH and EZH2 in breast cancer. Carcinogenesis 2011;32:2-9.
    • (2011) Carcinogenesis , vol.32 , pp. 2-9
    • Zhang, B.1    Liu, X.X.2    He, J.R.3    Zhou, C.X.4    Guo, M.5    He, M.6
  • 14
    • 84874428589 scopus 로고    scopus 로고
    • CPEB1 regulates the expression of MTDH/AEG-1 and glioblastoma cell migration
    • Kochanek DM, Wells DG. CPEB1 regulates the expression of MTDH/AEG-1 and glioblastoma cell migration. Mol Cancer Res 2013;11:149-160.
    • (2013) Mol Cancer Res , vol.11 , pp. 149-160
    • Kochanek, D.M.1    Wells, D.G.2
  • 15
    • 33751257780 scopus 로고    scopus 로고
    • Astrocyte elevated gene-1 (AEG-1) is a target gene of oncogenic Ha-ras requiring phosphatidylinositol 3-kinase and c-Myc
    • Lee SG, Su ZZ, Emdad L, Sarkar D, Fisher PB. Astrocyte elevated gene-1 (AEG-1) is a target gene of oncogenic Ha-ras requiring phosphatidylinositol 3-kinase and c-Myc. Proc Natl Acad Sci U S A 2006;103:17390-17395.
    • (2006) Proc Natl Acad Sci U S A , vol.103 , pp. 17390-17395
    • Lee, S.G.1    Su, Z.Z.2    Emdad, L.3    Sarkar, D.4    Fisher, P.B.5
  • 16
    • 10044285749 scopus 로고    scopus 로고
    • High-throughput tissue microarray analysis of c-myc activation in chronic liver diseases and hepatocellular carcinoma
    • Chan KL, Guan XY, Ng IO. High-throughput tissue microarray analysis of c-myc activation in chronic liver diseases and hepatocellular carcinoma. Hum Pathol 2004;35:1324-1331.
    • (2004) Hum Pathol , vol.35 , pp. 1324-1331
    • Chan, K.L.1    Guan, X.Y.2    Ng, I.O.3
  • 17
    • 0036890030 scopus 로고    scopus 로고
    • Prognostic significance of c-myc and AIB1 amplification in hepatocellular carcinoma. A broad survey using high-throughput tissue microarray
    • Wang Y, Wu MC, Sham JS, Zhang W, Wu WQ, Guan XY. Prognostic significance of c-myc and AIB1 amplification in hepatocellular carcinoma. A broad survey using high-throughput tissue microarray. Cancer 2002;95:2346-2352.
    • (2002) Cancer , vol.95 , pp. 2346-2352
    • Wang, Y.1    Wu, M.C.2    Sham, J.S.3    Zhang, W.4    Wu, W.Q.5    Guan, X.Y.6
  • 18
    • 0035076288 scopus 로고    scopus 로고
    • Comparative genomic hybridization of hepatocellular carcinoma: correlation with fluorescence in situ hybridization in paraffin-embedded tissue
    • Rao UN, Gollin SM, Beaves S, Cieply K, Nalesnik M, Michalopoulos GK. Comparative genomic hybridization of hepatocellular carcinoma: correlation with fluorescence in situ hybridization in paraffin-embedded tissue. Mol Diagn 2001;6:27-37.
    • (2001) Mol Diagn , vol.6 , pp. 27-37
    • Rao, U.N.1    Gollin, S.M.2    Beaves, S.3    Cieply, K.4    Nalesnik, M.5    Michalopoulos, G.K.6
  • 19
    • 70350066361 scopus 로고    scopus 로고
    • Nuclear LYRIC/AEG-1 interacts with PLZF and relieves PLZF-mediated repression
    • Thirkettle HJ, Mills IG, Whitaker HC, Neal DE. Nuclear LYRIC/AEG-1 interacts with PLZF and relieves PLZF-mediated repression. Oncogene 2009;28:3663-3670.
    • (2009) Oncogene , vol.28 , pp. 3663-3670
    • Thirkettle, H.J.1    Mills, I.G.2    Whitaker, H.C.3    Neal, D.E.4
  • 22
    • 0027245446 scopus 로고
    • Transgenic mouse model for synergistic effects of nuclear oncogenes and growth factors in tumorigenesis: interaction of c-myc and transforming growth factor alpha in hepatic oncogenesis
    • Murakami H, Sanderson ND, Nagy P, Marino PA, Merlino G, Thorgeirsson SS. Transgenic mouse model for synergistic effects of nuclear oncogenes and growth factors in tumorigenesis: interaction of c-myc and transforming growth factor alpha in hepatic oncogenesis. Cancer Res 1993;53:1719-1723.
    • (1993) Cancer Res , vol.53 , pp. 1719-1723
    • Murakami, H.1    Sanderson, N.D.2    Nagy, P.3    Marino, P.A.4    Merlino, G.5    Thorgeirsson, S.S.6
  • 23
    • 12144291647 scopus 로고    scopus 로고
    • Down-regulation of c-myc and Cyclin D1 genes by antisense oligodeoxy nucleotides inhibits the expression of E2F1 and in vitro growth of HepG2 and Morris 5123 liver cancer cells
    • Simile MM, De Miglio MR, Muroni MR, Frau M, Asara G, Serra S, et al. Down-regulation of c-myc and Cyclin D1 genes by antisense oligodeoxy nucleotides inhibits the expression of E2F1 and in vitro growth of HepG2 and Morris 5123 liver cancer cells. Carcinogenesis 2004;25:333-341.
    • (2004) Carcinogenesis , vol.25 , pp. 333-341
    • Simile, M.M.1    De Miglio, M.R.2    Muroni, M.R.3    Frau, M.4    Asara, G.5    Serra, S.6
  • 24
    • 33750617327 scopus 로고    scopus 로고
    • Oncogene-specific gene expression signatures at preneoplastic stage in mice define distinct mechanisms of hepatocarcinogenesis
    • Coulouarn C, Gomez-Quiroz LE, Lee JS, Kaposi-Novak P, Conner EA, Goldina TA, et al. Oncogene-specific gene expression signatures at preneoplastic stage in mice define distinct mechanisms of hepatocarcinogenesis. Hepatology 2006;44:1003-1011.
    • (2006) Hepatology , vol.44 , pp. 1003-1011
    • Coulouarn, C.1    Gomez-Quiroz, L.E.2    Lee, J.S.3    Kaposi-Novak, P.4    Conner, E.A.5    Goldina, T.A.6
  • 25
    • 7744220635 scopus 로고    scopus 로고
    • MYC inactivation uncovers pluripotent differentiation and tumour dormancy in hepatocellular cancer
    • Shachaf CM, Kopelman AM, Arvanitis C, Karlsson A, Beer S, Mandl S, et al. MYC inactivation uncovers pluripotent differentiation and tumour dormancy in hepatocellular cancer. Nature 2004;431:1112-1117.
    • (2004) Nature , vol.431 , pp. 1112-1117
    • Shachaf, C.M.1    Kopelman, A.M.2    Arvanitis, C.3    Karlsson, A.4    Beer, S.5    Mandl, S.6
  • 26
    • 0027242415 scopus 로고
    • The matrix secreted by 804G cells contains laminin-related components that participate in hemidesmosome assembly in vitro
    • Langhofer M, Hopkinson SB, Jones JC. The matrix secreted by 804G cells contains laminin-related components that participate in hemidesmosome assembly in vitro. J Cell Sci 1993;105:753-764.
    • (1993) J Cell Sci , vol.105 , pp. 753-764
    • Langhofer, M.1    Hopkinson, S.B.2    Jones, J.C.3
  • 27
    • 77958471357 scopus 로고    scopus 로고
    • Differential expression analysis for sequence count data
    • Anders S, Huber W. Differential expression analysis for sequence count data. Genome Biol 2010;11:R106.
    • (2010) Genome Biol , vol.11 , pp. R106
    • Anders, S.1    Huber, W.2
  • 30
    • 9644254191 scopus 로고    scopus 로고
    • Application of comparative functional genomics to identify best-fit mouse models to study human cancer
    • Lee JS, Chu IS, Mikaelyan A, Calvisi DF, Heo J, Reddy JK, Thorgeirsson SS. Application of comparative functional genomics to identify best-fit mouse models to study human cancer. Nat Genet 2004;36:1306-1311.
    • (2004) Nat Genet , vol.36 , pp. 1306-1311
    • Lee, J.S.1    Chu, I.S.2    Mikaelyan, A.3    Calvisi, D.F.4    Heo, J.5    Reddy, J.K.6    Thorgeirsson, S.S.7
  • 31
    • 60449087921 scopus 로고    scopus 로고
    • EpCAM-positive hepatocellular carcinoma cells are tumor-initiating cells with stem/progenitor cell features
    • Yamashita T, Ji J, Budhu A, Forgues M, Yang W, Wang HY, et al. EpCAM-positive hepatocellular carcinoma cells are tumor-initiating cells with stem/progenitor cell features. Gastroenterology 2009;136:1012-1024.
    • (2009) Gastroenterology , vol.136 , pp. 1012-1024
    • Yamashita, T.1    Ji, J.2    Budhu, A.3    Forgues, M.4    Yang, W.5    Wang, H.Y.6
  • 35
    • 0032905924 scopus 로고    scopus 로고
    • c-Myc target genes involved in cell growth, apoptosis, and metabolism
    • Dang CV. c-Myc target genes involved in cell growth, apoptosis, and metabolism. Mol Cell Biol 1999;19:1-11.
    • (1999) Mol Cell Biol , vol.19 , pp. 1-11
    • Dang, C.V.1
  • 36
    • 40449089338 scopus 로고    scopus 로고
    • Molecular basis of nuclear factor-kappaB activation by astrocyte elevated gene-1
    • Sarkar D, Park ES, Emdad L, Lee SG, Su ZZ, Fisher PB. Molecular basis of nuclear factor-kappaB activation by astrocyte elevated gene-1. Cancer Res 2008;68:1478-1484.
    • (2008) Cancer Res , vol.68 , pp. 1478-1484
    • Sarkar, D.1    Park, E.S.2    Emdad, L.3    Lee, S.G.4    Su, Z.Z.5    Fisher, P.B.6
  • 38
    • 77955284408 scopus 로고    scopus 로고
    • Segmental paternal uniparental disomy (patUPD) of 14q32 with abnormal methylation elicits the characteristic features of complete patUPD14
    • Irving MD, Buiting K, Kanber D, Donaghue C, Schulz R, Offiah A, et al. Segmental paternal uniparental disomy (patUPD) of 14q32 with abnormal methylation elicits the characteristic features of complete patUPD14. Am J Med Genet A 2010;152A:1942-1950.
    • (2010) Am J Med Genet A , vol.152 , pp. 1942-1950
    • Irving, M.D.1    Buiting, K.2    Kanber, D.3    Donaghue, C.4    Schulz, R.5    Offiah, A.6
  • 40
    • 77952425747 scopus 로고    scopus 로고
    • Aberrant silencing of imprinted genes on chromosome 12qF1 in mouse induced pluripotent stem cells
    • Stadtfeld M, Apostolou E, Akutsu H, Fukuda A, Follett P, Natesan S, et al. Aberrant silencing of imprinted genes on chromosome 12qF1 in mouse induced pluripotent stem cells. Nature 2010;465:175-181.
    • (2010) Nature , vol.465 , pp. 175-181
    • Stadtfeld, M.1    Apostolou, E.2    Akutsu, H.3    Fukuda, A.4    Follett, P.5    Natesan, S.6
  • 44
    • 80052245751 scopus 로고    scopus 로고
    • DLK1-DIO3 genomic imprinted microRNA cluster at 14q32.2 defines a stemlike subtype of hepatocellular carcinoma associated with poor survival
    • Luk JM, Burchard J, Zhang C, Liu AM, Wong KF, Shek FH, et al. DLK1-DIO3 genomic imprinted microRNA cluster at 14q32.2 defines a stemlike subtype of hepatocellular carcinoma associated with poor survival. J Biol Chem 2011;286:30706-30713.
    • (2011) J Biol Chem , vol.286 , pp. 30706-30713
    • Luk, J.M.1    Burchard, J.2    Zhang, C.3    Liu, A.M.4    Wong, K.F.5    Shek, F.H.6


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