Comparative genomic hybridization of hepatocellular carcinoma: Correlation with fluorescence In Situ hybridization in paraffin-embedded tissue

Molecular Diagnosis

Volumn 6, Issue 1, 2001, Pages 27-37

  Rao, Uma N M ^a   Gollin, Susanne M ^b,c   Beaves, Stacie ^b,c   Cieply, Kathleen ^a   Nalesnik, Michael ^a   Michalopoulos, George K ^a  

^a PRESBYTERIAN UNIVERSITY HOSPITAL   (United States)

^b UNIVERSITY OF PITTSBURGH GRADUATE SCHOOL OF PUBLIC HEALTH   (United States)

^c UNIVERSITY OF PITTSBURGH CANCER INSTITUTE   (United States)

Author keywords

CGH; FISH; Hepatocellular carcinoma

Indexed keywords

DNA; PARAFFIN;

ARTICLE; CHROMOSOME 7Q; CHROMOSOME 8Q; CHROMOSOME ABERRATION; COMPARATIVE GENOMIC HYBRIDIZATION; CONTROLLED STUDY; CYTOGENETICS; FLUORESCENCE IN SITU HYBRIDIZATION; HUMAN; HUMAN TISSUE; LIVER CELL CARCINOMA;

EID: 0035076288     PISSN: 10848592     EISSN: None     Source Type: Journal    
DOI: 10.1054/modi.2001.22021     Document Type: Article

References (55)

1. Hepatobiliary neoplasms
2. Pathogenesis of hepatocellular carcinoma: A review from the viewpoint of molecular analysis
3. Alterations of tumor suppressor genes and allelic losses in human hepatocellular carcinomas in China
4. Accumulation of genetic changes during development and progression of HCC. Loss of heterozygosity arm 1p occurs at an early stage of hepatocarcinogenesis
5. Gene expressions of c-met and hepatocyte growth factor in liver disease and hepatocellular carcinoma
6. Cell cycle regulators and human hepatocarcinogenesis
7. Expression of HGF, its receptor c-met, c-myc, and albumin in cirrhotic and neoplastic human liver tissue
8. Allelotype study of primary hepatocellular carcinoma
9. Allele loss on chromosome 16. Associated with progression of human hepatocellular carcinoma
10. Loss of somatic heterozygosity in hepatocellular carcinoma
11. p53 as a growth suppressor gene in HBV-related hepatocellular carcinoma cells
12. Extensive analysis of duplicated-inverted hepatitis B virus integrations in human hepatocellular carcinoma
13. Integration of hepatitis B virus and alteration of the 1p36 region found in cancerous tissue of primary hepatocellular carcinoma with viral replication evidenced only in noncancerous, cirrhotic tissue
14. Fibrolamellar carcinoma of the liver: An immunohistochemical study of nineteen cases and a review of the literature
15. Excessive collagen formation in fibrolamellar carcinoma of the liver: A morphological and biochemical study
16. HBV-DNA sequences in tumor and non tumor tissue in a patient with the fibrolamellar variant of hepatocellular carcinoma
17. Nonrandom breakpoints of unbalanced chromosome translocations in human hepatocellular carcinoma cell lines
18. Cytogenetic studies on human liver cancer cell lines
19. Report of a complex karyotype in recurrent metastatic fibrolamellar carcinoma and a review of hepatocellular carcinoma cytogenetics
20. Frequent rearrangements of chromosomes 1, 7, and 8 in primary liver cancer
21. Interphase cytogenetic studies of human hepatocellular carcinomas by fluorescent in situ hybridization
22. Numerical chromosome aberrations in hepatocellular carcinoma detected by fluorescence in situ hybridization
23. Investigation of chromosomal aberrations in hepatocellular carcinoma by fluorescence in situ hybridization
24. Chromosomal aberrations in hepatocellular carcinomas: Relationship with pathological features
25. Trisomy 1 and 8 occur frequently in HCC but not in liver cell adenoma and focal nodular hyperplasia. A fluorescence in situ hybridization study
26. Comparative genomic hybridization: A rapid new method for detecting and mapping DNA amplification in tumors
27. Comparative genomic hybridization. An overview
28. Detection of complete and partial chromosome gains and losses by comparative genomic in situ hybridization
29. Recurrent chromosomal abnormalities in hepatocellular carcinoma detected by comparative genomic hybridization
30. Assessment of genetic changes in hepatocellular carcinoma by comparative genomic hybridization analysis. Relationship to disease stage, tumor size and cirrhosis
31. Genetic aberrations detected by comparative genomic hybridization in hepatocellular carcinomas: Their relationship to clinicopathological features
32. Chromosomal aberrations in human hepatocellular carcinomas associated with hepatitis C virus infection detected by comparative genomic hybridization
33. Novel recurrent genetic imbalances in human hepatocellular carcinoma cell lines identified by comparative genomic hybridization
34. Regional mapping of the human hepatocyte growth factor (HGF)-scatter factor gene to chromosome 7q21.1
35. Liver hepatocyte growth factor does not always correlate with hepatocellular proliferation in human liver lesions: Its specific receptor c-met does
36. Liver (including intrahepatic bile ducts)
37. Primary carcinomas of the liver. A study of 100 cases among 48,900 necropsies
38. Enhanced tumorigenicity and invasion-metastasis by hepatocyte growth factor/scatter factor-met signaling in human cells concomitant with induction of the urokinase proteolysis network
39. Expression of hepatocyte growth factor and its receptor c-met proto-oncogene in hepatocellular carcinoma
40. Chromosome 1p aberrations are frequent in human primary hepatocellular carcinoma
41. Interphase cytogenetic analysis reveals numerical chromosome aberrations in large liver cell dysplasia
42. Loss of heterozygosity of the long arm of chromosome 7 in follicular and anaplastic thyroid cancer but not in papillary cancer
43. Trisomy 7-harbouring non-random duplication of the mutant MET allele in hereditary papillary renal carcinomas
44. Adult cirrhotic explants: Precancerous lesions and undetected small hepatocellular carcinomas
45. Detailed deletion mapping with a refined physical map of 7q31 localizes a putative tumor suppressor gene for breast cancer in the region of MET
46. Liver transplantation and incidental primary tumors
47. Liver transplantation for hepatocellular carcinoma. A registry report of the impact of tumor characteristics on outcome
48. Myc-Max-Mad: A transcription factor network controlling cell cycle progression, differentiation and death
49. Oncogenetic activity of the c-myc protein requires dimerization with Max
50. Amplification of c-myc in hepatocellular carcinoma: Correlation with clinicopathological features, proliferative activity and p53 overexpression
51. Transient excess of MYC activity can elicit genomic instability and tumorigenisis
52. Genetic alterations in hepatocellular carcinomas: Association between loss of chromosome 4q and p53 gene mutations
53. An approach to definition of genetic alterations in prostate cancer
54. Chromosomal aneuploidy in proliferative breast disease
55. Chromosome 1 aneusomy, identified by interphase cytogenetics in mammographically detected ductal carcinoma in situ of breast