-
1
-
-
34250020201
-
Hepatocellular carcinoma: Epidemiology and molecular carcinogenesis
-
El-Serag, H.B., and Rudolph, K.L. 2007. Hepatocellular carcinoma: epidemiology and molecular carcinogenesis. Gastroenterology. 132:2557-2576.
-
(2007)
Gastroenterology
, vol.132
, pp. 2557-2576
-
-
El-Serag, H.B.1
Rudolph, K.L.2
-
2
-
-
0642303165
-
The continuing increase in the incidence of hepatocellular carcinoma in the United States: An update
-
El-Serag, H.B., Davila, J.A., Petersen, N.J., and McGlynn, K.A. 2003. The continuing increase in the incidence of hepatocellular carcinoma in the United States: an update. Ann. Intern. Med. 139:817-823.
-
(2003)
Ann. Intern. Med
, vol.139
, pp. 817-823
-
-
El-Serag, H.B.1
Davila, J.A.2
Petersen, N.J.3
McGlynn, K.A.4
-
3
-
-
41349099104
-
Cancer statistics, 2008
-
Jemal, A., et al. 2008. Cancer statistics, 2008. CA Cancer J. Clin. 58:71-96.
-
(2008)
CA Cancer J. Clin
, vol.58
, pp. 71-96
-
-
Jemal, A.1
-
4
-
-
40549100994
-
Biology of hepatocellular carcinoma
-
Pang, R.W., et al. 2008. Biology of hepatocellular carcinoma. Ann. Surg. Oncol. 15:962-971.
-
(2008)
Ann. Surg. Oncol
, vol.15
, pp. 962-971
-
-
Pang, R.W.1
-
5
-
-
0037096866
-
A phase II trial of gemcitabine in patients with advanced hepatocellular carcinoma
-
Fuchs, C.S., et al. 2002. A phase II trial of gemcitabine in patients with advanced hepatocellular carcinoma. Cancer. 94:3186-3191.
-
(2002)
Cancer
, vol.94
, pp. 3186-3191
-
-
Fuchs, C.S.1
-
6
-
-
33646567160
-
Systematic review: Evidence-based management of hepatocellular carcinoma - an updated analysis of randomized controlled trials
-
Lopez, P.M., Villanueva, A., and Llovet, J.M. 2006. Systematic review: evidence-based management of hepatocellular carcinoma - an updated analysis of randomized controlled trials. Aliment Pharmacol. Ther. 23:1535-1547.
-
(2006)
Aliment Pharmacol. Ther
, vol.23
, pp. 1535-1547
-
-
Lopez, P.M.1
Villanueva, A.2
Llovet, J.M.3
-
7
-
-
27144557565
-
A randomized phase III study of doxorubicin versus cisplatin/interferon alpha-2b/doxorubicin/fluorouracil (PIAF) combination chemotherapy for unresectable hepatocellular carcinoma
-
Yeo, W., et al. 2005. A randomized phase III study of doxorubicin versus cisplatin/interferon alpha-2b/doxorubicin/fluorouracil (PIAF) combination chemotherapy for unresectable hepatocellular carcinoma. J. Natl. Cancer Inst. 97:1532-1538.
-
(2005)
J. Natl. Cancer Inst
, vol.97
, pp. 1532-1538
-
-
Yeo, W.1
-
8
-
-
0032879468
-
Prognosis of hepatocellular carcinoma: The BCLC staging classification
-
Llovet, J.M., Bru, C., and Bruix, J. 1999. Prognosis of hepatocellular carcinoma: the BCLC staging classification. Semin. Liver Dis. 19:329-338.
-
(1999)
Semin. Liver Dis
, vol.19
, pp. 329-338
-
-
Llovet, J.M.1
Bru, C.2
Bruix, J.3
-
9
-
-
38049092935
-
Hepatocellular carcinoma: The role of the North American GI Steering Committee Hepatobiliary Task Force and the advent of effective drug therapy
-
O'Neil, B.H., and Venook, A.P. 2007. Hepatocellular carcinoma: the role of the North American GI Steering Committee Hepatobiliary Task Force and the advent of effective drug therapy. Oncologist. 12:1425-1432.
-
(2007)
Oncologist
, vol.12
, pp. 1425-1432
-
-
O'Neil, B.H.1
Venook, A.P.2
-
10
-
-
50949120748
-
Radiofrequency ablation and chemoembolization for hepatocellular carcinoma
-
Georgiades, C.S., Hong, K., and Geschwind, J.F. 2008. Radiofrequency ablation and chemoembolization for hepatocellular carcinoma. Cancer J. 14:117-122.
-
(2008)
Cancer J
, vol.14
, pp. 117-122
-
-
Georgiades, C.S.1
Hong, K.2
Geschwind, J.F.3
-
11
-
-
0037308133
-
Systematic review of randomized trials for unresectable hepatocellular carcinoma: Chemoembolization improves survival
-
Llovet, J.M., and Bruix, J. 2003. Systematic review of randomized trials for unresectable hepatocellular carcinoma: Chemoembolization improves survival. Hepatology. 37:429-442.
-
(2003)
Hepatology
, vol.37
, pp. 429-442
-
-
Llovet, J.M.1
Bruix, J.2
-
13
-
-
0032765871
-
Complete pathological remission is possible with systemic combination chemotherapy for inoperable hepatocellular carcinoma
-
Leung, T.W., et al. 1999. Complete pathological remission is possible with systemic combination chemotherapy for inoperable hepatocellular carcinoma. Clin. Cancer Res. 5:1676-1681.
-
(1999)
Clin. Cancer Res
, vol.5
, pp. 1676-1681
-
-
Leung, T.W.1
-
14
-
-
0033497580
-
Durable clinical and pathologic response of hepatocellular carcinoma to systemic and hepatic arterial administration of platinol, recombinant interferon alpha 2B, doxorubicin, and 5-fluorouracil: A communication
-
Patt, Y.Z., et al. 1999. Durable clinical and pathologic response of hepatocellular carcinoma to systemic and hepatic arterial administration of platinol, recombinant interferon alpha 2B, doxorubicin, and 5-fluorouracil: a communication. Am. J. Clin. Oncol. 22:209-213.
-
(1999)
Am. J. Clin. Oncol
, vol.22
, pp. 209-213
-
-
Patt, Y.Z.1
-
15
-
-
33749017926
-
Phase II study of sorafenib in patients with advanced hepatocellular carcinoma
-
Abou-Alfa, G.K., et al. 2006. Phase II study of sorafenib in patients with advanced hepatocellular carcinoma. J. Clin. Oncol. 24:4293-4300.
-
(2006)
J. Clin. Oncol
, vol.24
, pp. 4293-4300
-
-
Abou-Alfa, G.K.1
-
16
-
-
38149123239
-
Sorafenib: In hepatocellular carcinoma
-
Simpson, D., and Keating, G.M. 2008. Sorafenib: in hepatocellular carcinoma. Drugs. 68:251-258.
-
(2008)
Drugs
, vol.68
, pp. 251-258
-
-
Simpson, D.1
Keating, G.M.2
-
17
-
-
47949116252
-
Sorafenib in advanced hepatocellular carcinoma
-
Llovet, J.M., et al. 2008. Sorafenib in advanced hepatocellular carcinoma. N. Engl. J. Med. 359:378-390.
-
(2008)
N. Engl. J. Med
, vol.359
, pp. 378-390
-
-
Llovet, J.M.1
-
18
-
-
33646351795
-
Phase II study of gemcitabine and oxaliplatin in combination with bevacizumab in patients with advanced hepatocellular carcinoma
-
Zhu, A.X., et al. 2006. Phase II study of gemcitabine and oxaliplatin in combination with bevacizumab in patients with advanced hepatocellular carcinoma. J. Clin. Oncol. 24:1898-1903.
-
(2006)
J. Clin. Oncol
, vol.24
, pp. 1898-1903
-
-
Zhu, A.X.1
-
19
-
-
54449083925
-
Molecular targeted therapies in hepatocellular carcinoma
-
Llovet, J.M., and Bruix, J. 2008. Molecular targeted therapies in hepatocellular carcinoma. Hepatology. 48:1312-1327.
-
(2008)
Hepatology
, vol.48
, pp. 1312-1327
-
-
Llovet, J.M.1
Bruix, J.2
-
20
-
-
0019313239
-
Presence of integrated hepatitis B virus DNA sequences in cellular DNA of human hepatocellular carcinoma
-
Brechot, C., Pourcel, C., Louise, A., Rain, B., and Tiollais, P. 1980. Presence of integrated hepatitis B virus DNA sequences in cellular DNA of human hepatocellular carcinoma. Nature. 286:533-535.
-
(1980)
Nature
, vol.286
, pp. 533-535
-
-
Brechot, C.1
Pourcel, C.2
Louise, A.3
Rain, B.4
Tiollais, P.5
-
21
-
-
0030902570
-
Hepatitis B virus X antigen in the pathogenesis of chronic infections and the development of hepatocellular carcinoma
-
Feitelson, M.A., and Duan, L.X. 1997. Hepatitis B virus X antigen in the pathogenesis of chronic infections and the development of hepatocellular carcinoma. Am. J. Pathol. 150:1141-1157.
-
(1997)
Am. J. Pathol
, vol.150
, pp. 1141-1157
-
-
Feitelson, M.A.1
Duan, L.X.2
-
22
-
-
0034852454
-
p53-dependent transcriptional repression of p21(waf1) by hepatitis C virus NS3
-
Kwun, H.J., Jung, E.Y., Ahn, J.Y., Lee, M.N., and Jang, K.L. 2001. p53-dependent transcriptional repression of p21(waf1) by hepatitis C virus NS3. J. Gen. Virol. 82:2235-2241.
-
(2001)
J. Gen. Virol
, vol.82
, pp. 2235-2241
-
-
Kwun, H.J.1
Jung, E.Y.2
Ahn, J.Y.3
Lee, M.N.4
Jang, K.L.5
-
23
-
-
0036713601
-
Hepatitis C virus core protein represses the p21 promoter through inhibition of a TGF-beta pathway
-
Lee, M.N., et al. 2002. Hepatitis C virus core protein represses the p21 promoter through inhibition of a TGF-beta pathway. J. Gen. Virol. 83:2145-2151.
-
(2002)
J. Gen. Virol
, vol.83
, pp. 2145-2151
-
-
Lee, M.N.1
-
24
-
-
33846463379
-
Transcriptome classification of HCC is related to gene alterations and to new therapeutic targets
-
Boyault, S., et al. 2007. Transcriptome classification of HCC is related to gene alterations and to new therapeutic targets. Hepatology. 45:42-52.
-
(2007)
Hepatology
, vol.45
, pp. 42-52
-
-
Boyault, S.1
-
25
-
-
33947587168
-
Prognostic molecular markers in hepatocellular carcinoma: A systematic review
-
Mann, C.D., et al. 2007. Prognostic molecular markers in hepatocellular carcinoma: a systematic review. Eur. J. Cancer. 43:979-992.
-
(2007)
Eur. J. Cancer
, vol.43
, pp. 979-992
-
-
Mann, C.D.1
-
26
-
-
34249845990
-
Genetics of hepatocellular carcinoma
-
Teufel, A., et al. 2007. Genetics of hepatocellular carcinoma. World J. Gastroenterol. 13:2271-2282.
-
(2007)
World J. Gastroenterol
, vol.13
, pp. 2271-2282
-
-
Teufel, A.1
-
27
-
-
0031561127
-
Increased MAPK expression and activity in primary human hepatocellular carcinoma
-
Schmidt, C.M., McKillop, I.H., Cahill, P.A., and Sitzmann, J.V. 1997. Increased MAPK expression and activity in primary human hepatocellular carcinoma. Biochem. Biophys. Res. Commun. 236:54-58.
-
(1997)
Biochem. Biophys. Res. Commun
, vol.236
, pp. 54-58
-
-
Schmidt, C.M.1
McKillop, I.H.2
Cahill, P.A.3
Sitzmann, J.V.4
-
28
-
-
0030715557
-
Altered expression of mitogen-activated protein kinases in a rat model of experimental hepatocellular carcinoma
-
McKillop, I.H., Schmidt, C.M., Cahill, P.A., and Sitzmann, J.V. 1997. Altered expression of mitogen-activated protein kinases in a rat model of experimental hepatocellular carcinoma. Hepatology. 26:1484-1491.
-
(1997)
Hepatology
, vol.26
, pp. 1484-1491
-
-
McKillop, I.H.1
Schmidt, C.M.2
Cahill, P.A.3
Sitzmann, J.V.4
-
29
-
-
0036830564
-
PI3K-FRAP/mTOR pathway is critical for hepatocyte proliferation whereas MEK/ERK supports both proliferation and survival
-
Coutant, A., et al. 2002. PI3K-FRAP/mTOR pathway is critical for hepatocyte proliferation whereas MEK/ERK supports both proliferation and survival. Hepatology. 36:1079-1088.
-
(2002)
Hepatology
, vol.36
, pp. 1079-1088
-
-
Coutant, A.1
-
30
-
-
57349087153
-
-
Villanueva, A., et al. 2008. Pivotal role of mTOR signaling in hepatocellular carcinoma. Gastroenterology. 135:1972-1983.e1-e11.
-
Villanueva, A., et al. 2008. Pivotal role of mTOR signaling in hepatocellular carcinoma. Gastroenterology. 135:1972-1983.e1-e11.
-
-
-
-
31
-
-
4644324186
-
NF-kappaB functions as a tumour promoter in inflammation-associated cancer
-
Pikarsky, E., et al. 2004. NF-kappaB functions as a tumour promoter in inflammation-associated cancer. Nature. 431:461-466.
-
(2004)
Nature
, vol.431
, pp. 461-466
-
-
Pikarsky, E.1
-
32
-
-
34248674146
-
WNT/ beta-catenin signaling in liver health and disease
-
Thompson, M.D., and Monga, S.P. 2007. WNT/ beta-catenin signaling in liver health and disease. Hepatology. 45:1298-1305.
-
(2007)
Hepatology
, vol.45
, pp. 1298-1305
-
-
Thompson, M.D.1
Monga, S.P.2
-
33
-
-
33746808398
-
Wnt/beta-catenin signaling in development and disease
-
Clevers, H. 2006. Wnt/beta-catenin signaling in development and disease. Cell. 127:469-480.
-
(2006)
Cell
, vol.127
, pp. 469-480
-
-
Clevers, H.1
-
34
-
-
33751073938
-
Cross-talk of WNT and FGF signaling pathways at GSK3beta to regulate beta-catenin and SNAIL signaling cascades
-
Katoh, M., and Katoh, M. 2006. Cross-talk of WNT and FGF signaling pathways at GSK3beta to regulate beta-catenin and SNAIL signaling cascades. Cancer Biol. Ther. 5:1059-1064.
-
(2006)
Cancer Biol. Ther
, vol.5
, pp. 1059-1064
-
-
Katoh, M.1
Katoh, M.2
-
35
-
-
0029994517
-
A new member of the frizzled family from Drosophila functions as a Wingless receptor
-
Bhanot, P., et al. 1996. A new member of the frizzled family from Drosophila functions as a Wingless receptor. Nature. 382:225-230.
-
(1996)
Nature
, vol.382
, pp. 225-230
-
-
Bhanot, P.1
-
36
-
-
0034727078
-
An LDL-receptor-related protein mediates Wnt signalling in mice
-
Pinson, K.I., Brennan, J., Monkley, S., Avery, B.J., and Skarnes, W.C. 2000. An LDL-receptor-related protein mediates Wnt signalling in mice. Nature. 407:535-538.
-
(2000)
Nature
, vol.407
, pp. 535-538
-
-
Pinson, K.I.1
Brennan, J.2
Monkley, S.3
Avery, B.J.4
Skarnes, W.C.5
-
37
-
-
0034727104
-
LDL-receptor-related proteins in Wnt signal transduction
-
Tamai, K., et al. 2000. LDL-receptor-related proteins in Wnt signal transduction. Nature. 407:530-535.
-
(2000)
Nature
, vol.407
, pp. 530-535
-
-
Tamai, K.1
-
38
-
-
1542347695
-
Convergence of Wnt, beta-catenin, and cadherin pathways
-
Nelson, W.J., and Nusse, R. 2004. Convergence of Wnt, beta-catenin, and cadherin pathways. Science. 303:1483-1487.
-
(2004)
Science
, vol.303
, pp. 1483-1487
-
-
Nelson, W.J.1
Nusse, R.2
-
39
-
-
0030978351
-
beta-catenin is a target for the ubiquitin-proteasome pathway
-
Aberle, H., Bauer, A., Stappert, J., Kispert, A., and Kemler, R. 1997. beta-catenin is a target for the ubiquitin-proteasome pathway. EMBO J. 16:3797-3804.
-
(1997)
EMBO J
, vol.16
, pp. 3797-3804
-
-
Aberle, H.1
Bauer, A.2
Stappert, J.3
Kispert, A.4
Kemler, R.5
-
40
-
-
0029781509
-
Functional interaction of beta-catenin with the transcription factor LEF-1
-
Behrens, J., et al. 1996. Functional interaction of beta-catenin with the transcription factor LEF-1. Nature. 382:638-642.
-
(1996)
Nature
, vol.382
, pp. 638-642
-
-
Behrens, J.1
-
41
-
-
3242706980
-
Pygopus and Legless target Armadillo/beta-catenin to the nucleus to enable its transcriptional co-activator function
-
Townsley, F.M., Cliffe, A., and Bienz, M. 2004. Pygopus and Legless target Armadillo/beta-catenin to the nucleus to enable its transcriptional co-activator function. Nat. Cell Biol. 6:626-633.
-
(2004)
Nat. Cell Biol
, vol.6
, pp. 626-633
-
-
Townsley, F.M.1
Cliffe, A.2
Bienz, M.3
-
42
-
-
0032497513
-
Drosophila Tcf and Groucho interact to repress Wingless signalling activity
-
Cavallo, R.A., et al. 1998. Drosophila Tcf and Groucho interact to repress Wingless signalling activity. Nature. 395:604-608.
-
(1998)
Nature
, vol.395
, pp. 604-608
-
-
Cavallo, R.A.1
-
43
-
-
33745542960
-
C-terminal-binding protein directly activates and represses Wnt transcriptional targets in Drosophila
-
Fang, M., et al. 2006. C-terminal-binding protein directly activates and represses Wnt transcriptional targets in Drosophila. EMBO J. 25:2735-2745.
-
(2006)
EMBO J
, vol.25
, pp. 2735-2745
-
-
Fang, M.1
-
44
-
-
53049086329
-
Focal gains of VEGFA and molecular classification of hepatocellular carcinoma
-
Chiang, D.Y., et al. 2008. Focal gains of VEGFA and molecular classification of hepatocellular carcinoma. Cancer Res. 68:6779-6788.
-
(2008)
Cancer Res
, vol.68
, pp. 6779-6788
-
-
Chiang, D.Y.1
-
45
-
-
0037130449
-
Mutational spectrum of beta-catenin, AXIN1, and AXIN2 in hepatocellular carcinomas and hepatoblastomas
-
Taniguchi, K., et al. 2002. Mutational spectrum of beta-catenin, AXIN1, and AXIN2 in hepatocellular carcinomas and hepatoblastomas. Oncogene. 21:4863-4871.
-
(2002)
Oncogene
, vol.21
, pp. 4863-4871
-
-
Taniguchi, K.1
-
46
-
-
0345006147
-
Somatic mutations of the beta-catenin gene are frequent in mouse and human hepatocellular carcinomas
-
de La Coste, A., et al. 1998. Somatic mutations of the beta-catenin gene are frequent in mouse and human hepatocellular carcinomas. Proc. Natl. Acad. Sci. U. S. A. 95:8847-8851.
-
(1998)
Proc. Natl. Acad. Sci. U. S. A
, vol.95
, pp. 8847-8851
-
-
de La Coste, A.1
-
47
-
-
5144226941
-
Functional consequences of frizzled-7 receptor overexpression in human hepatocellular carcinoma
-
Merle, P., et al. 2004. Functional consequences of frizzled-7 receptor overexpression in human hepatocellular carcinoma. Gastroenterology. 127:1110-1122.
-
(2004)
Gastroenterology
, vol.127
, pp. 1110-1122
-
-
Merle, P.1
-
48
-
-
0032525836
-
Activation of the betacatenin gene in primary hepatocellular carcinomas by somatic alterations involving exon 3
-
Miyoshi, Y., et al. 1998. Activation of the betacatenin gene in primary hepatocellular carcinomas by somatic alterations involving exon 3. Cancer Res. 58:2524-2527.
-
(1998)
Cancer Res
, vol.58
, pp. 2524-2527
-
-
Miyoshi, Y.1
-
49
-
-
0034088858
-
AXIN1 mutations in hepatocellular carcinomas, and growth suppression in cancer cells by virus-mediated transfer of AXIN1
-
Satoh, S., et al. 2000. AXIN1 mutations in hepatocellular carcinomas, and growth suppression in cancer cells by virus-mediated transfer of AXIN1. Nat. Genet. 24:245-250.
-
(2000)
Nat. Genet
, vol.24
, pp. 245-250
-
-
Satoh, S.1
-
50
-
-
10344254872
-
Liver-targeted disruption of Apc in mice activates beta-catenin signaling and leads to hepatocellular carcinomas
-
Colnot, S., et al. 2004. Liver-targeted disruption of Apc in mice activates beta-catenin signaling and leads to hepatocellular carcinomas. Proc. Natl. Acad. Sci. U. S. A. 101:17216-17221.
-
(2004)
Proc. Natl. Acad. Sci. U. S. A
, vol.101
, pp. 17216-17221
-
-
Colnot, S.1
-
51
-
-
1642535593
-
Hepatocarcinogenesis in mice with beta-catenin and Ha-ras gene mutations
-
Harada, N., et al. 2004. Hepatocarcinogenesis in mice with beta-catenin and Ha-ras gene mutations. Cancer Res. 64:48-54.
-
(2004)
Cancer Res
, vol.64
, pp. 48-54
-
-
Harada, N.1
-
52
-
-
0035266134
-
Activation of beta-catenin during hepatocarcinogenesis in transgenic mouse models: Relationship to phenotype and tumor grade
-
Calvisi, D.F., Factor, V.M., Loi, R., and Thorgeirsson, S.S. 2001. Activation of beta-catenin during hepatocarcinogenesis in transgenic mouse models: relationship to phenotype and tumor grade. Cancer Res. 61:2085-2091.
-
(2001)
Cancer Res
, vol.61
, pp. 2085-2091
-
-
Calvisi, D.F.1
Factor, V.M.2
Loi, R.3
Thorgeirsson, S.S.4
-
53
-
-
0037118589
-
Identification and cloning of human astrocyte genes displaying elevated expression after infection with HIV-1 or exposure to HIV-1 envelope glycoprotein by rapid subtraction hybridization, RaSH
-
Su, Z.Z., et al. 2002. Identification and cloning of human astrocyte genes displaying elevated expression after infection with HIV-1 or exposure to HIV-1 envelope glycoprotein by rapid subtraction hybridization, RaSH. Oncogene. 21:3592-3602.
-
(2002)
Oncogene
, vol.21
, pp. 3592-3602
-
-
Su, Z.Z.1
-
54
-
-
20444389341
-
Cloning and characterization of HIV-1-inducible astrocyte elevated gene-1, AEG-1
-
Kang, D.C., et al. 2005. Cloning and characterization of HIV-1-inducible astrocyte elevated gene-1, AEG-1. Gene. 353:8-15.
-
(2005)
Gene
, vol.353
, pp. 8-15
-
-
Kang, D.C.1
-
55
-
-
1842634484
-
Metadherin, a cell surface protein in breast tumors that mediates lung metastasis
-
Brown, D.M., and Ruoslahti, E. 2004. Metadherin, a cell surface protein in breast tumors that mediates lung metastasis. Cancer Cell. 5:365-374.
-
(2004)
Cancer Cell
, vol.5
, pp. 365-374
-
-
Brown, D.M.1
Ruoslahti, E.2
-
56
-
-
1242339604
-
3D3/lyric: A novel transmembrane protein of the endoplasmic reticulum and nuclear envelope, which is also present in the nucleolus
-
Sutherland, H.G., Lam, Y.W., Briers, S., Lamond, A.I., and Bickmore, W.A. 2004. 3D3/lyric: a novel transmembrane protein of the endoplasmic reticulum and nuclear envelope, which is also present in the nucleolus. Exp. Cell Res. 294:94-105.
-
(2004)
Exp. Cell Res
, vol.294
, pp. 94-105
-
-
Sutherland, H.G.1
Lam, Y.W.2
Briers, S.3
Lamond, A.I.4
Bickmore, W.A.5
-
57
-
-
32944459561
-
Activation of the nuclear factor kappaB pathway by astrocyte elevated gene-1: Implications for tumor progression and metastasis
-
Emdad, L., et al. 2006. Activation of the nuclear factor kappaB pathway by astrocyte elevated gene-1: implications for tumor progression and metastasis. Cancer Res. 66:1509-1516.
-
(2006)
Cancer Res
, vol.66
, pp. 1509-1516
-
-
Emdad, L.1
-
58
-
-
40449089338
-
Molecular basis of nuclear factor-kappaB activation by astrocyte elevated gene-1
-
Sarkar, D., et al. 2008. Molecular basis of nuclear factor-kappaB activation by astrocyte elevated gene-1. Cancer Res. 68:1478-1484.
-
(2008)
Cancer Res
, vol.68
, pp. 1478-1484
-
-
Sarkar, D.1
-
59
-
-
34147165551
-
Astrocyte elevated gene-1: Recent insights into a novel gene involved in tumor progression, metastasis and neurodegeneration
-
Emdad, L., et al. 2007. Astrocyte elevated gene-1: recent insights into a novel gene involved in tumor progression, metastasis and neurodegeneration. Pharmacol. Ther. 114:155-170.
-
(2007)
Pharmacol. Ther
, vol.114
, pp. 155-170
-
-
Emdad, L.1
-
60
-
-
36849061266
-
Knockdown of astrocyteelevated gene-1 inhibits prostate cancer progression through upregulation of FOXO3a activity
-
Kikuno, N., et al. 2007. Knockdown of astrocyteelevated gene-1 inhibits prostate cancer progression through upregulation of FOXO3a activity. Oncogene. 26:7647-7655.
-
(2007)
Oncogene
, vol.26
, pp. 7647-7655
-
-
Kikuno, N.1
-
61
-
-
33751257780
-
Astrocyte elevated gene-1 (AEG-1) is a target gene of oncogenic Ha-ras requiring phosphatidylinositol 3-kinase and c-Myc
-
Lee, S.G., Su, Z.Z., Emdad, L., Sarkar, D., and Fisher, P.B. 2006. Astrocyte elevated gene-1 (AEG-1) is a target gene of oncogenic Ha-ras requiring phosphatidylinositol 3-kinase and c-Myc. Proc. Natl. Acad. Sci. U. S. A. 103:17390-17395.
-
(2006)
Proc. Natl. Acad. Sci. U. S. A
, vol.103
, pp. 17390-17395
-
-
Lee, S.G.1
Su, Z.Z.2
Emdad, L.3
Sarkar, D.4
Fisher, P.B.5
-
62
-
-
39149100913
-
Astrocyte elevated gene-1 activates cell survival pathways through PI3K-Akt signaling
-
Lee, S.G., et al. 2008. Astrocyte elevated gene-1 activates cell survival pathways through PI3K-Akt signaling. Oncogene. 27:1114-1121.
-
(2008)
Oncogene
, vol.27
, pp. 1114-1121
-
-
Lee, S.G.1
-
63
-
-
0023718915
-
Inhibitory effect of parvovirus H-1 on cultured human tumour cells or transformed cells
-
Su, Z.Z., Luo, Z.Y., Guo, L.P., Li, J.Z., and Liu, Y.L. 1988. Inhibitory effect of parvovirus H-1 on cultured human tumour cells or transformed cells. Sci. Sin. [B]. 31:69-80.
-
(1988)
Sci. Sin. [B]
, vol.31
, pp. 69-80
-
-
Su, Z.Z.1
Luo, Z.Y.2
Guo, L.P.3
Li, J.Z.4
Liu, Y.L.5
-
64
-
-
0038387494
-
5-fluorouracil: Mechanisms of action and clinical strategies
-
Longley, D.B., Harkin, D.P., and Johnston, P.G. 2003. 5-fluorouracil: mechanisms of action and clinical strategies. Nat. Rev. Cancer. 3:330-338.
-
(2003)
Nat. Rev. Cancer
, vol.3
, pp. 330-338
-
-
Longley, D.B.1
Harkin, D.P.2
Johnston, P.G.3
-
65
-
-
33846458275
-
The importance of cytochrome P450 2B6 in the human metabolism of environmental chemicals
-
Hodgson, E., and Rose, R.L. 2007. The importance of cytochrome P450 2B6 in the human metabolism of environmental chemicals. Pharmacol. Ther. 113:420-428.
-
(2007)
Pharmacol. Ther
, vol.113
, pp. 420-428
-
-
Hodgson, E.1
Rose, R.L.2
-
66
-
-
0042062300
-
Gene expression in colorectal cancer and in vitro chemosensitivity to 5-fluorouracil: A study of 88 surgical specimens
-
Yoshinare, K., et al. 2003. Gene expression in colorectal cancer and in vitro chemosensitivity to 5-fluorouracil: a study of 88 surgical specimens. Cancer Sci. 94:633-638.
-
(2003)
Cancer Sci
, vol.94
, pp. 633-638
-
-
Yoshinare, K.1
-
67
-
-
23744479830
-
The role of thymidylate synthase and dihydropyrimidine dehydrogenase in resistance to 5-fluorouracil in human lung cancer cells
-
Oguri, T., et al. 2005. The role of thymidylate synthase and dihydropyrimidine dehydrogenase in resistance to 5-fluorouracil in human lung cancer cells. Lung Cancer. 49:345-351.
-
(2005)
Lung Cancer
, vol.49
, pp. 345-351
-
-
Oguri, T.1
-
68
-
-
33846826935
-
MRP8/ABCC11 directly confers resistance to 5-fluorouracil
-
Oguri, T., et al. 2007. MRP8/ABCC11 directly confers resistance to 5-fluorouracil. Mol. Cancer Ther. 6:122-127.
-
(2007)
Mol. Cancer Ther
, vol.6
, pp. 122-127
-
-
Oguri, T.1
-
69
-
-
0034282755
-
Inhibition of the mammalian transcription factor LSF induces S-phase-dependent apoptosis by downregulating thymidylate synthase expression
-
Powell, C.M., Rudge, T.L., Zhu, Q., Johnson, L.F., and Hansen, U. 2000. Inhibition of the mammalian transcription factor LSF induces S-phase-dependent apoptosis by downregulating thymidylate synthase expression. EMBO J. 19:4665-4675.
-
(2000)
EMBO J
, vol.19
, pp. 4665-4675
-
-
Powell, C.M.1
Rudge, T.L.2
Zhu, Q.3
Johnson, L.F.4
Hansen, U.5
-
70
-
-
23844551736
-
Claudin-3 and claudin-4 expression in ovarian epithelial cells enhances invasion and is associated with increased matrix metalloproteinase-2 activity
-
Agarwal, R., D'Souza, T., and Morin, P.J. 2005. Claudin-3 and claudin-4 expression in ovarian epithelial cells enhances invasion and is associated with increased matrix metalloproteinase-2 activity. Cancer Res. 65:7378-7385.
-
(2005)
Cancer Res
, vol.65
, pp. 7378-7385
-
-
Agarwal, R.1
D'Souza, T.2
Morin, P.J.3
-
71
-
-
33746886963
-
Systemic induction of the angiogenesis switch by the tetraspanin D6.1A/CO-029
-
Gesierich, S., Berezovskiy, I., Ryschich, E., and Zoller, M. 2006. Systemic induction of the angiogenesis switch by the tetraspanin D6.1A/CO-029. Cancer Res. 66:7083-7094.
-
(2006)
Cancer Res
, vol.66
, pp. 7083-7094
-
-
Gesierich, S.1
Berezovskiy, I.2
Ryschich, E.3
Zoller, M.4
-
72
-
-
33748747409
-
Expression cloning identifies transgelin (SM22) as a novel repressor of 92-kDa type IV collagenase (MMP-9) expression
-
Nair, R.R., Solway, J., and Boyd, D.D. 2006. Expression cloning identifies transgelin (SM22) as a novel repressor of 92-kDa type IV collagenase (MMP-9) expression. J. Biol. Chem. 281:26424-26436.
-
(2006)
J. Biol. Chem
, vol.281
, pp. 26424-26436
-
-
Nair, R.R.1
Solway, J.2
Boyd, D.D.3
-
73
-
-
38849168162
-
Oncogenic BRAF induces senescence and apoptosis through pathways mediated by the secreted protein IGFBP7
-
Wajapeyee, N., Serra, R.W., Zhu, X., Mahalingam, M., and Green, M.R. 2008. Oncogenic BRAF induces senescence and apoptosis through pathways mediated by the secreted protein IGFBP7. Cell. 132:363-374.
-
(2008)
Cell
, vol.132
, pp. 363-374
-
-
Wajapeyee, N.1
Serra, R.W.2
Zhu, X.3
Mahalingam, M.4
Green, M.R.5
-
74
-
-
23044500915
-
Pyruvate kinase type M2 and its role in tumor growth and spreading
-
Mazurek, S., Boschek, C.B., Hugo, F., and Eigenbrodt, E. 2005. Pyruvate kinase type M2 and its role in tumor growth and spreading. Semin. Cancer Biol. 15:300-308.
-
(2005)
Semin. Cancer Biol
, vol.15
, pp. 300-308
-
-
Mazurek, S.1
Boschek, C.B.2
Hugo, F.3
Eigenbrodt, E.4
-
75
-
-
34447343780
-
Downregulation of Wnt signaling is a trigger for formation of facultative heterochromatin and onset of cell senescence in primary human cells
-
Ye, X., et al. 2007. Downregulation of Wnt signaling is a trigger for formation of facultative heterochromatin and onset of cell senescence in primary human cells. Mol. Cell. 27:183-196.
-
(2007)
Mol. Cell
, vol.27
, pp. 183-196
-
-
Ye, X.1
-
76
-
-
0037031887
-
Wnt-3A/beta-catenin signaling induces transcription from the LEF-1 promoter
-
Filali, M., Cheng, N., Abbott, D., Leontiev, V., and Engelhardt, J.F. 2002. Wnt-3A/beta-catenin signaling induces transcription from the LEF-1 promoter. J. Biol. Chem. 277:33398-33410.
-
(2002)
J. Biol. Chem
, vol.277
, pp. 33398-33410
-
-
Filali, M.1
Cheng, N.2
Abbott, D.3
Leontiev, V.4
Engelhardt, J.F.5
-
77
-
-
0019226759
-
Phenotypic stability of adult rat hepatocytes in primary monolayer culture
-
Bissell, D.M., and Guzelian, P.S. 1980. Phenotypic stability of adult rat hepatocytes in primary monolayer culture. Ann. N. Y. Acad. Sci. 349:85-98.
-
(1980)
Ann. N. Y. Acad. Sci
, vol.349
, pp. 85-98
-
-
Bissell, D.M.1
Guzelian, P.S.2
-
78
-
-
34347216741
-
Eradication of therapy-resistant human prostate tumors using a cancer terminator virus
-
Sarkar, D., et al. 2007. Eradication of therapy-resistant human prostate tumors using a cancer terminator virus. Cancer Res. 67:5434-5442.
-
(2007)
Cancer Res
, vol.67
, pp. 5434-5442
-
-
Sarkar, D.1
-
79
-
-
34247549347
-
Genome-wide molecular profiles of HCV-induced dysplasia and hepatocellular carcinoma
-
Wurmbach, E., et al. 2007. Genome-wide molecular profiles of HCV-induced dysplasia and hepatocellular carcinoma. Hepatology. 45:938-947.
-
(2007)
Hepatology
, vol.45
, pp. 938-947
-
-
Wurmbach, E.1
|