Freedom and constraint in engineered noncolinear polyketide assembly lines

Chemistry and Biology

Volumn 22, Issue 2, 2015, Pages 229-240

  Sugimoto, Yuki ^a   Ishida, Keishi ^a   Traitcheva, Nelly ^a   Busch, Benjamin ^a   Dahse, Hans Martin ^a   Hertweck, Christian ^a,b  

^a HANS KNÖLL INSTITUTE   (Germany)

^b FRIEDRICH SCHILLER UNIVERSITY JENA   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

NEOAUREOTHIN; POLYKETIDE; POLYKETIDE SYNTHASE; UNCLASSIFIED DRUG; AUREOTHIN; CHROMONE DERIVATIVE; PYRONE DERIVATIVE; SPECTINABILIN;

ANTIBACTERIAL ACTIVITY; ANTIPROLIFERATIVE ACTIVITY; ARTICLE; CATALYSIS; GENE CLUSTER; GENE EXPRESSION; HETEROLOGOUS EXPRESSION; HUMAN; HUMAN CELL; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; STRUCTURE ACTIVITY RELATION; BACILLUS SUBTILIS; CELL PROLIFERATION; CHEMISTRY; DRUG EFFECTS; ENZYMOLOGY; FUNGUS; GENETICS; HELA CELL LINE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; METABOLISM; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; MICROBIAL SENSITIVITY TEST; MUTATION; STAPHYLOCOCCUS AUREUS; STREPTOMYCES; UMBILICAL VEIN ENDOTHELIAL CELL;

BACILLUS SUBTILIS; CELL PROLIFERATION; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CHROMONES; FUNGI; HELA CELLS; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; MASS SPECTROMETRY; METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS; MICROBIAL SENSITIVITY TESTS; MUTATION; POLYKETIDE SYNTHASES; PYRONES; STAPHYLOCOCCUS AUREUS; STREPTOMYCES;

EID: 84923139137     PISSN: 10745521     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.chembiol.2014.12.014     Document Type: Article

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