Analysis of modular-iterative mixed biosynthesis of lankacidin by heterologous expression and gene fusion

Journal of Antibiotics

Volumn 60, Issue 11, 2007, Pages 700-708

  Tatsuno, Satoshi ^a   Arakawa, Kenji ^a   Kinashi, Haruyasu ^a  

^a HIROSHIMA UNIVERSITY   (Japan)

Author keywords

Antibiotic; Biosynthesis; Lankacidin; Linear plasmid; Polyketide synthase; Streptomyces

Indexed keywords

LANKACIDIN; LANKACIDINOL A; MACROLIDE; UNCLASSIFIED DRUG; ANTIINFECTIVE AGENT; LANKACIDINS; PRIMER DNA;

ARTICLE; DRUG ISOLATION; DRUG SYNTHESIS; GENE CLUSTER; GENE FUSION; HETEROLOGOUS EXPRESSION; NONHUMAN; PLASMID; POLYMERIZATION; PRIORITY JOURNAL; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; STREPTOMYCES LIVIDANS; BIOSYNTHESIS; ELECTROSPRAY MASS SPECTROMETRY; GENE EXPRESSION REGULATION; GENETICS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; METABOLISM; MULTIGENE FAMILY; THIN LAYER CHROMATOGRAPHY;

STREPTOMYCES; STREPTOMYCES LIVIDANS; STREPTOMYCES ROCHEI;

ANTI-BACTERIAL AGENTS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CHROMATOGRAPHY, THIN LAYER; DNA PRIMERS; GENE EXPRESSION REGULATION, FUNGAL; GENE FUSION; MACROLIDES; MULTIGENE FAMILY; PLASMIDS; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; STREPTOMYCES LIVIDANS;

EID: 40949135410     PISSN: 00218820     EISSN: None     Source Type: Journal    
DOI: 10.1038/ja.2007.90     Document Type: Article

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