Development and in silico analysis of a new nitrogen-limited feeding strategy for fed-batch cultures of Pichia pastoris based on a simple pH-control system

Biochemical Engineering Journal

Volumn 98, Issue , 2015, Pages 1-9

  Irani, Zahra Azimzadeh ^a   Maghsoudi, Amir ^b   Shojaosadati, Seyed Abbas ^a   Motamedian, Ehsan ^a  

^a TARBIAT MODARES UNIVERSITY   (Iran)

^b NATIONAL INSTITUTE OF GENETIC ENGINEERING AND BIOTECHNOLOGY   (Iran)

Author keywords

Control; Fed batch culture; Fermentation; Metabolic model; Nitrogen limitation; Protein

Indexed keywords

AMMONIA; AMMONIUM HYDROXIDE; BATCH CELL CULTURE; CONTROL ENGINEERING; CONTROL SYSTEMS; FERMENTATION; METABOLISM; NITROGEN; OXYGEN; PROTEINS; YEAST;

CONTROL STRATEGIES; FED-BATCH CULTURES; FEEDING STRATEGIES; HIGH CELL DENSITY CULTURES; INTRACELLULAR REACTIONS; METABOLIC MODELING; NITROGEN LIMITATION; PENTOSE PHOSPHATE PATHWAY;

CONTROLLERS;

ALCOHOL OXIDASE; AMMONIA; FUNGAL PROTEIN; NITROGEN; OXYGEN; RECOMBINANT HUMAN SERUM ALBUMIN;

ARTICLE; BIOMASS; CELL DENSITY; CELL METABOLISM; CONTROL SYSTEM; CONTROLLED STUDY; ENZYME ACTIVITY; FED BATCH CULTURE; GLYCOLYSIS; GROWTH RATE; KOMAGATAELLA PASTORIS; MICROBIAL GROWTH; NONHUMAN; PENTOSE PHOSPHATE CYCLE; PH; PREDICTION; PRIORITY JOURNAL; YEAST;

PICHIA PASTORIS;

EID: 84922979722     PISSN: 1369703X     EISSN: 1873295X     Source Type: Journal    
DOI: 10.1016/j.bej.2015.02.016     Document Type: Article

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