Differential expression of microRNAs in ischemic heart disease

Drug Discovery Today

Volumn 20, Issue 2, 2015, Pages 223-235

  Song, Minwoo A ^a   Paradis, Alexandra N ^a   Gay, Maresha S ^a   Shin, John ^a   Zhang, Lubo ^a  

^a LOMA LINDA UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL MARKER; MICRORNA; RAS PROTEIN;

ANGIOGENESIS; APOPTOSIS; BIOGENESIS; CARDIOVASCULAR SYSTEM; CELL DEATH; CELL SURVIVAL; GENE EXPRESSION; GENETIC VARIABILITY; HEART ARRHYTHMIA; HEART HYPERTROPHY; HEART MUSCLE CELL; HEART MUSCLE FIBROSIS; HEART PROTECTION; HUMAN; ISCHEMIC HEART DISEASE; ISCHEMIC PRECONDITIONING; PROTEIN EXPRESSION; PROTEIN RNA BINDING; RENIN ANGIOTENSIN ALDOSTERONE SYSTEM; REPERFUSION INJURY; REVIEW; ANIMAL; GENETICS; HEART INFARCTION PREVENTION; HEART MUSCLE ISCHEMIA; METABOLISM;

ANIMALS; BIOMARKERS; HUMANS; ISCHEMIC PRECONDITIONING, MYOCARDIAL; MICRORNAS; MYOCARDIAL ISCHEMIA; RENIN-ANGIOTENSIN SYSTEM;

EID: 84922954051     PISSN: 13596446     EISSN: 18785832     Source Type: Journal    
DOI: 10.1016/j.drudis.2014.10.004     Document Type: Review

References (120)

1. D.P. Bartel MicroRNAs: genomics, biogenesis, mechanism, and function Cell 116 2004 281 297
2. B. Khraiwesh Transcriptional control of gene expression by microRNAs Cell 140 1 2010 111 122
3. H. Zhu, and G.C. Fan Role of microRNAs in the reperfused myocardium towards post-infarct remodelling Cardiovasc. Res. 94 2012 284 292
4. S. Cardin Role for microRNA-21 in atrial profibrillatory fibrotic remodeling associated with experimental postinfarction heart failure Circ. Arrhythm. Electrophysiol. 5 2012 1027 1035
5. P. Lv Circulating miR-208b and miR-34a are associated with left ventricular remodeling after acute myocardial infarction Int. J. Mol. Sci. 15 2014 5774 5788
6. A. Osbourne Downregulation of connexin43 by microRNA-130a in cardiomyocytes results in cardiac arrhythmias J. Mol. Cell. Cardiol. 74c 2014 53 63
7. R.C. Kukreja MicroRNAs: new players in cardiac injury and protection Mol. Pharmacol. 80 2011 558 564
8. Y. Ye The role of microRNA in modulating myocardial ischemia-reperfusion injury Physiol. Genomics 43 2011 534 542
9. R.C. Friedman Most mammalian mRNAs are conserved targets of microRNAs Genome Res. 19 2009 92 105
10. J.D. Port Temporal expression of miRNAs and mRNAs in a mouse model of myocardial infarction Physiol. Genomics 43 2011 1087 1095
11. Y. D'Alessandra Circulating microRNAs are new and sensitive biomarkers of myocardial infarction Eur. Heart J. 31 2010 2765 2773
12. O. Gidlöf Cardiospecific microRNA plasma levels correlate with troponin and cardiac function in patients with ST elevation myocardial infarction, are selectively dependent on renal elimination, and can be detected in urine samples Cardiology 118 2011 217 226
13. K.H. Yeom Characterization of DGCR8/Pasha, the essential cofactor for Drosha in primary miRNA processing Nucleic Acids Res. 34 2006 4622 4629
14. R.I. Gregory The Microprocessor complex mediates the genesis of microRNAs Nature 432 2004 235 240
15. E. Basyuk Human let-7 stem-loop precursors harbor features of RNase III cleavage products Nucleic Acids Res. 31 2003 6593 6597
16. Y. Lee The nuclear RNase III Drosha initiates microRNA processing Nature 425 2003 415 419
17. R. Yi Exportin-5 mediates the nuclear export of pre-microRNAs and short hairpin RNAs Genes Dev. 17 2003 3011 3016
18. E. Lund Nuclear export of microRNA precursors Science 303 2004 95 98
19. D.S. Schwarz Asymmetry in the assembly of the RNAi enzyme complex Cell 115 2003 199 208
20. A. Khvorova Functional siRNAs and miRNAs exhibit strand bias Cell 115 2003 209 216
21. S. Nottrott Human let-7a miRNA blocks protein production on actively translating polyribosomes Nat. Struct. Mol. Biol. 13 2006 1108 1114
22. R.S. Pillai Inhibition of translational initiation by Let-7 microRNA in human cells Science 309 2005 1573 1576
23. D.T. Humphreys MicroRNAs control translation initiation by inhibiting eukaryotic initiation factor 4E/cap and poly(A) tail function Proc. Natl. Acad. Sci. U. S. A. 102 2005 16961 16966
24. X.C. Ding, and H. Grosshans Repression of C. elegans microRNA targets at the initiation level of translation requires GW182 proteins EMBO J. 28 2009 213 222
25. G. Mathonnet MicroRNA inhibition of translation initiation in vitro by targeting the cap-binding complex eIF4F Science 317 2007 1764 1767
26. J.R. Lytle Target mRNAs are repressed as efficiently by microRNA-binding sites in the 5′ UTR as in the 3′ UTR Proc. Natl. Acad. Sci. U. S. A. 104 2007 9667 9672
27. C.P. Petersen Short RNAs repress translation after initiation in mammalian cells Mol. Cell 21 2006 533 542
28. S. Gu Biological basis for restriction of microRNA targets to the 3' untranslated region in mammalian mRNAs Nat. Struct. Mol. Biol. 16 2009 144 150
29. K. Friend A conserved PUF-Ago-eEF1A complex attenuates translation elongation Nat. Struct. Mol. Biol. 19 2012 176 183
30. A. Eulalio Deadenylation is a widespread effect of miRNA regulation RNA 15 2009 21 32
31. World Health Organization Global Status Report on Noncommunicable Diseases 2010. Geneva. 2011
32. P.A. Heidenreich Forecasting the future of cardiovascular disease in the United States: a policy statement from the American Heart Association Circulation 123 2011 933 944
33. M.C. Fishbein The histopathologic evolution of myocardial infarction Chest J. 73 1978 843 849
34. S.D. Fihn 2012 ACCF/AHA/ACP/AATS/PCNA/SCAI/STS Guideline for the Diagnosis and Management of Patients With Stable Ischemic Heart Disease: executive summary J. Am. Coll. Cardiol. 60 2012 2564 2603
35. J.A. Blumenthal Exercise and pharmacological treatment of depressive symptoms in patients with coronary heart disease: results from the UPBEAT (Understanding the Prognostic Benefits of Exercise and Antidepressant Therapy) study J. Am. Coll. Cardiol. 60 2012 1053 1063
36. C. Li Circulating microRNAs as novel and sensitive biomarkers of acute myocardial infarction Clin. Biochem. 45 2012 727 732
37. E. Nabialek Circulating microRNAs (miR-423-5p, miR-208a and miR-1) in acute myocardial infarction and stable coronary heart disease Minerva Cardioangiol. 61 2013 627 637
38. J.A. Ward Circulating cell and plasma microRNA profiles differ between non-ST-segment and ST-segment-elevation myocardial infarction Fam. Med. Med. Sci. Res. 2 2013 108
39. B. Meder MicroRNA signatures in total peripheral blood as novel biomarkers for acute myocardial infarction Basic Res. Cardiol. 106 2011 13 23
40. R.E. Nunez Angiotensin II and ischemic preconditioning synergize to improve mitochondrial function while showing additive effects on ventricular post-ischemic recovery J. Cardiovasc. Pharmacol. 64 2014 172 179
41. Y. Hou Beta-adrenoceptor regulates miRNA expression in rat heart Med. Sci. Mon. Int. Med. J. Exp. Clin. Res. 18 2012 BR309
42. R. Kulshreshtha A microRNA signature of hypoxia Mol. Cell Biol. 27 2007 1859 1867
43. J. Pouyssegur Hypoxia signalling in cancer and approaches to enforce tumour regression Nature 441 2006 437 443
44. Y. Lu MicroRNA-1 downregulation by propranolol in a rat model of myocardial infarction: a new mechanism for ischaemic cardioprotection Cardiovasc. Res. 84 2009 434 441
45. S. Ikeda MicroRNA-1 negatively regulates expression of the hypertrophy-associated calmodulin and Mef2a genes Mol. Cell Biol. 29 2009 2193 2204
46. N. Liu An intragenic MEF2-dependent enhancer directs muscle-specific expression of microRNAs 1 and 133 Proc. Natl. Acad. Sci. U. S. A. 104 2007 20844 20849
47. F.M. Drawnel Mutual antagonism between IP(3)RII and miRNA-133a regulates calcium signals and cardiac hypertrophy J. Cell Biol. 199 2012 783 798
48. O. Adam Role of miR-21 in the pathogenesis of atrial fibrosis Basic Res. Cardiol. 107 2012 278
49. X. Luo MicroRNA-26 governs profibrillatory inward-rectifier potassium current changes in atrial fibrillation J. Clin. Invest. 123 2013 1939 1951
50. B.N. Finck The PPAR regulatory system in cardiac physiology and disease Cardiovasc. Res. 73 2007 269 277
51. P. Fasanaro microRNA: emerging therapeutic targets in acute ischemic diseases Pharmacol. Ther. 125 2010 92 104
52. K.H. Shi Role of microRNAs in atrial fibrillation: new insights and perspectives Cell Signal. 25 2013 2079 2084
53. B. Yang The muscle-specific microRNA miR-1 regulates cardiac arrhythmogenic potential by targeting GJA1 and KCNJ2 Nat. Med. 13 2007 486 491
54. Y. Cheng A translational study of circulating cell-free microRNA-1 in acute myocardial infarction Clin. Sci. (Lond.) 119 2010 87 95
55. A. Curcio MicroRNA-1 downregulation increases connexin 43 displacement and induces ventricular tachyarrhythmias in rodent hypertrophic hearts PLOS ONE 8 2013 e70158
56. A.A. Sovari Inhibition of c-Src tyrosine kinase prevents angiotensin II-mediated connexin-43 remodeling and sudden cardiac death J. Am. Coll. Cardiol. 58 2011 2332 2339
57. I. Karakikes Therapeutic cardiac-targeted delivery of miR-1 reverses pressure overload-induced cardiac hypertrophy and attenuates pathological remodeling J. Am. Heart Assoc. 2 2013 e000078
58. D. Terentyev miR-1 overexpression enhances Ca(2+) release and promotes cardiac arrhythmogenesis by targeting PP2A regulatory subunit B56alpha and causing CaMKII-dependent hyperphosphorylation of RyR2 Circ. Res. 104 2009 514 521
59. A.E. Belevych MicroRNA-1 and -133 increase arrhythmogenesis in heart failure by dissociating phosphatase activity from RyR2 complex PLOS ONE 6 2011 e28324
60. Y. Lu MicroRNA-328 contributes to adverse electrical remodeling in atrial fibrillation Circulation 122 2010 2378 2387
61. T.Y. Ling Regulation of the SK3 channel by microRNA-499 - potential role in atrial fibrillation Heart Rhythm 10 2013 1001 1009
62. D.L. Dong Reciprocal repression between microRNA-133 and calcineurin regulates cardiac hypertrophy: a novel mechanism for progressive cardiac hypertrophy Hypertension 55 2010 946 952
63. Q. Li Attenuation of microRNA-1 derepresses the cytoskeleton regulatory protein twinfilin-1 to provoke cardiac hypertrophy J. Cell Sci. 123 2010 2444 2452
64. A. Care MicroRNA-133 controls cardiac hypertrophy Nat. Med. 13 2007 613 618
65. C. Bang Cardiac fibroblast-derived microRNA passenger strand-enriched exosomes mediate cardiomyocyte hypertrophy J. Clin. Invest. 124 2014 2136 2146
66. R.F. Duisters miR-133 and miR-30 regulate connective tissue growth factor: implications for a role of microRNAs in myocardial matrix remodeling Circ. Res. 104 2009 170 178
67. G. Castoldi MiR-133a regulates collagen 1A1: potential role of miR-133a in myocardial fibrosis in angiotensin II-dependent hypertension J. Cell Physiol. 227 2012 850 856
68. P. Camelliti Structural and functional characterisation of cardiac fibroblasts Cardiovasc. Res. 65 2005 40 51
69. T. Thum MicroRNA-21 contributes to myocardial disease by stimulating MAP kinase signalling in fibroblasts Nature 456 2008 980 984
70. E. van Rooij Dysregulation of microRNAs after myocardial infarction reveals a role of miR-29 in cardiac fibrosis Proc. Natl. Acad. Sci. U. S. A. 105 2008 13027 13032
71. H.K. Eltzschig, and T. Eckle Ischemia and reperfusion - from mechanism to translation Nat. Med. 17 2011 1391 1401
72. A. Gross BCL-2 family members and the mitochondria in apoptosis Genes Dev. 13 1999 1899 1911
73. Y. Tang MicroRNA-1 regulates cardiomyocyte apoptosis by targeting Bcl-2 Int. Heart J. 50 2009 377 387
74. Z. Pan miR-1 exacerbates cardiac ischemia-reperfusion injury in mouse models PLOS ONE 7 2012 e50515
75. Y. Ye Downregulation of microRNA-29 by antisense inhibitors and a PPAR-gamma agonist protects against myocardial ischaemia-reperfusion injury Cardiovasc. Res. 87 2010 535 544
76. Y. Cheng MicroRNA-21 protects against the H(2)O(2)-induced injury on cardiac myocytes via its target gene PDCD4 J. Mol. Cell. Cardiol. 47 2009 5 14
77. Y. Cheng Ischaemic preconditioning-regulated miR-21 protects heart against ischaemia/reperfusion injury via anti-apoptosis through its target PDCD4 Cardiovasc. Res. 87 2010 431 439
78. S. Dong MicroRNA expression signature and the role of microRNA-21 in the early phase of acute myocardial infarction J. Biol. Chem. 284 2009 29514 29525
79. L. Wang, and L. Qian miR-24 regulates intrinsic apoptosis pathway in mouse cardiomyocytes PLOS ONE 9 2014 e85389
80. H.W. Kim Ischemic preconditioning augments survival of stem cells via miR-210 expression by targeting caspase-8-associated protein 2 J. Biol. Chem. 284 2009 33161 33168
81. D.F. Li Induction of microRNA-24 by HIF-1 protects against ischemic injury in rat cardiomyocytes Physiol. Res. 61 2012 555 565
82. L. Qian miR-24 inhibits apoptosis and represses Bim in mouse cardiomyocytes J. Exp. Med. 208 2011 549 560
83. R.K. Mutharasan microRNA-210 is upregulated in hypoxic cardiomyocytes through Akt- and p53-dependent pathways and exerts cytoprotective effects Am. J. Physiol. Heart Circ. Physiol. 301 2011 H1519 H1530
84. J. Fiedler MicroRNA-24 regulates vascularity after myocardial infarction Circulation 124 2011 720 730
85. P. Fasanaro MicroRNA-210 modulates endothelial cell response to hypoxia and inhibits the receptor tyrosine kinase ligand Ephrin-A3 J. Biol. Chem. 283 2008 15878 15883
86. S. Kuijper Regulation of angiogenesis by Eph-ephrin interactions Trends Cardiovasc. Med. 17 2007 145 151
87. M.A. Abengozar Blocking ephrinB2 with highly specific antibodies inhibits angiogenesis, lymphangiogenesis, and tumor growth Blood 119 2012 4565 4576
88. A.S. Go Heart disease and stroke statistics - 2013 update: a report from the American Heart Association Circulation 127 2013 e6 e245
89. C.E. Murry Preconditioning with ischemia: a delay of lethal cell injury in ischemic myocardium Circulation 74 1986 1124 1136
90. C. Yin A novel role of microRNA in late preconditioning: upregulation of endothelial nitric oxide synthase and heat shock protein 70 Circ. Res. 104 2009 572 575
91. M.E. Wilhide Identification of a NF-kappaB cardioprotective gene program: NF-kappaB regulation of Hsp70.1 contributes to cardioprotection after permanent coronary occlusion J. Mol. Cell. Cardiol. 51 2011 82 89
92. S.G. Ong, and D.J. Hausenloy Hypoxia-inducible factor as a therapeutic target for cardioprotection Pharmacol. Ther. 136 2012 69 81
93. F.N. Salloum Role of microRNAs in cardiac preconditioning J. Cardiovasc. Pharmacol. 56 2010 581 588
94. X. Duan Expression of microRNA-1 and microRNA-21 in different protocols of ischemic conditioning in an isolated rat heart model Cardiology 122 2012 36 43
95. B.A. Muller, and N.S. Dhalla Mechanisms of the beneficial actions of ischemic preconditioning on subcellular remodeling in ischemic-reperfused heart Curr. Cardiol. Rev. 6 2010 255 264
96. Z. Giricz Cardioprotection by remote ischemic preconditioning of the rat heart is mediated by extracellular vesicles J. Mol. Cell. Cardiol. 68 2014 75 78
97. J.R. Parratt Bradykinin as an endogenous myocardial protective substance with particular reference to ischemic preconditioning - a brief review of the evidence Can. J. Physiol. Pharmacol. 73 1995 837 842
98. Z.Y. Hu Emulsified isoflurane postconditioning produces cardioprotection against myocardial ischemia-reperfusion injury in rats J. Physiol. Sci. 63 2013 251 261
99. H. Takano Nitric oxide donors induce late preconditioning against myocardial stunning and infarction in conscious rabbits via an antioxidant-sensitive mechanism Circ. Res. 83 1998 73 84
100. C.Y. Chien Progressive thermopreconditioning attenuates rat cardiac ischemia/reperfusion injury by mitochondria-mediated antioxidant and antiapoptotic mechanisms J. Thorac. Cardiovasc. Surg. 148 2014 705 713
101. M. Muravyeva Preconditioning by isoflurane elicits mitochondrial protective mechanisms independent of sarcolemmal KATP channel in mouse cardiomyocytes J. Cardiovasc. Pharmacol. 61 2013 369 377
102. M.F. Linton, and S. Fazio A practical approach to risk assessment to prevent coronary artery disease and its complications Am. J. Cardiol. 92 2003 19 26
103. M.V. Kurian Enhanced cell survival and diminished apoptotic response to simulated ischemia-reperfusion in H9c2 cells by magnetic field preconditioning Apoptosis 17 2012 1182 1196
104. P. Abete Exercise training restores ischemic preconditioning in the aging heart J. Am. Coll. Cardiol. 36 2000 643 650
105. Z. Ma Swimming exercise training-induced left ventricular hypertrophy involves microRNAs and synergistic regulation of the PI3K/AKT/mTOR signaling pathway Eur. J. Appl. Physiol. 113 2013 2473 2486
106. Y.J. Shen Exercise preconditioning provides early cardioprotection against exhaustive exercise in rats: potential involvement of protein kinase C delta translocation Mol. Cell. Biochem. 368 2012 89 102
107. T. Fernandes Eccentric and concentric cardiac hypertrophy induced by exercise training: microRNAs and molecular determinants Braz. J. Med. Biol. Res. 44 2011 836 847
108. C. Dasgupta, and L. Zhang Angiotensin II receptors and drug discovery in cardiovascular disease Drug Discov. Today 16 2011 22 34
109. L. Oliveira The angiotensin II AT1 receptor structure-activity correlations in the light of rhodopsin structure Physiol. Rev. 87 2007 565 592
110. S. AbdAlla The angiotensin II AT2 receptor is an AT1 receptor antagonist J. Biol. Chem. 276 2001 39721 39726
111. R.A. Santos, and A.J. Ferreira Angiotensin-(1-7) and the renin-angiotensin system Curr. Opin. Nephrol. Hypertens. 16 2007 122 128
112. L. Shi Angiotensin-converting enzymes and drug discovery in cardiovascular diseases Drug Discov. Today 15 2010 332 341
113. W.G. Thomas, and H. Qian Arresting angiotensin type 1 receptors Trends Endocrinol. Metab. 14 2003 130 136
114. P.K. Mehta, and K.K. Griendling Angiotensin II cell signaling: physiological and pathological effects in the cardiovascular system Am. J. Physiol. Cell. Physiol. 292 2007 C82 C97
115. F. Folli Crosstalk between insulin and angiotensin II signalling systems Exp. Clin. Endocrinol. Diabetes 107 1999 133 139
116. 2 in angiotensin II-induced vascular hypertrophy Hypertension 32 1998 488 495
117. E. Schulz Nitric oxide, tetrahydrobiopterin, oxidative stress, and endothelial dysfunction in hypertension Antioxid. Redox. Signal. 10 2008 1115 1126
118. M. Bujak, and N.G. Frangogiannis The role of TGF-beta signaling in myocardial infarction and cardiac remodeling Cardiovasc. Res. 74 2007 184 195
119. J. Mair Cardiac troponin I in the diagnosis of myocardial injury and infarction Clin. Chim. Acta 245 1996 19 38
120. R.D. Kociol Troponin elevation in heart failure prevalence, mechanisms, and clinical implications J. Am. Coll. Cardiol. 56 2010 1071 1078