MiR-133a regulates collagen 1A1: Potential role of miR-133a in myocardial fibrosis in angiotensin II-dependent hypertension

Journal of Cellular Physiology

Volumn 227, Issue 2, 2012, Pages 850-856

  Castoldi, Giovanna ^a   di Gioia, Cira R T ^b   Bombardi, Camila ^a   Catalucci, Daniele ^c,d   Corradi, Barbara ^a   Gualazzi, Maria Giovanna ^d   Leopizzi, Martina ^b   Mancini, Massimiliano ^b   Zerbini, Gianpaolo ^e   Condorelli, Gianluigi ^c,d   Stella, Andrea ^a  

^a SAN GERARDO HOSPITAL   (Italy)

^b SAPIENZA UNIVERSITY OF ROME   (Italy)

^c CNR   (Italy)

^d IRCCS MULTIMEDICA   (Italy)

^e SAN RAFFAELE HOSPITAL   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ANGIOTENSIN II; COLLAGEN TYPE 1; COLLAGEN TYPE 1A1; LUCIFERASE; MESSENGER RNA; MICRORNA; MICRORNA 133A; MICRORNA 29B; UNCLASSIFIED DRUG;

3' UNTRANSLATED REGION; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BINDING SITE; CONTROLLED STUDY; DOWN REGULATION; GENE MUTATION; HEART MUSCLE FIBROSIS; HUMAN; HUMAN CELL; HYPERTENSION; IN VIVO STUDY; MALE; MORPHOMETRICS; NONHUMAN; OSMOTIC MINIPUMP; PRIORITY JOURNAL; RAT; REAL TIME POLYMERASE CHAIN REACTION; REPORTER GENE; SYSTOLIC BLOOD PRESSURE;

ANGIOTENSIN II; ANIMALS; COLLAGEN TYPE I; FIBROSIS; GENE EXPRESSION REGULATION; HEART DISEASES; HYPERTENSION; MALE; MICRORNAS; RATS; RATS, SPRAGUE-DAWLEY;

EID: 82155163832     PISSN: 00219541     EISSN: 10974652     Source Type: Journal    
DOI: 10.1002/jcp.22939     Document Type: Article

References (43)

1. Bartel DP. 2004. MicroRNAs: Genomics, biogenesis, mechanism, and function. Cell 116: 281-297.
2. Bauersachs J. 2010. Regulation of myocardial fibrosis by microRNAs. J Cardiovasc Pharmacol 56: 454-459.
3. Bishop JE, Lindahl G. 1999. Regulation of cardiovascular collagen synthesis by mechanical load. Cardiovasc Res 42: 27-44.
4. Bramlage P, Durand-Zaleski I, Desai N, Pirk O, Hacker C. 2009. The value of irbesartan in the management of hypertension. Expert Opin Pharmacother 10: 1817-1831.
5. Campos AH, Zhao Y, Pollman MJ, Gibbons GH. 2003. DNA microarray profiling to identify angiotensin-responsive genes in vascular smooth muscle cells: Potential mediators of vascular disease. Circ Res 92: 111-118.
6. Carè A, Catalucci D, Felicetti F, Bonci D, Addario A, Gallo P, Bang ML, Segnalini P, Gu Y, Dalton ND, Elia L, Latronico MV, Høydal M, Autore C, Russo MA, Dorn GW II, Ellingsen O, Ruiz-Lozano P, Peterson KL, Croce CM, Peschle C, Condorelli G. 2007. MicroRNA-133 controls cardiac hypertrophy. Nat Med 13: 613-618.
7. Cassis LA, Marshall DE, Fettinger MJ, Rosenbluth B, Lodder RA. 1998. Mechanisms contributing to angiotensin II regulation of body weight. Am J Physiol Endocrinol Metab 274: E867-E876.
8. Castoldi G, Di Gioia CR, Pieruzzi F, D'Orlando C, Van De Greef WM, Busca G, Sperti G, Stella A. 2003. ANG II increases TIMP-1 expression in rat aortic smooth muscle cells in vivo. Am J Physiol Heart Circ Physiol 284: H635-H643.
9. Castoldi G, Di Gioia CR, Travaglini C, Busca G, Redaelli S, Bombardi C, Stella A. 2007. Angiotensin II increases tissue-specific inhibitor of metalloproteinase-2 expression in rat aortic smooth muscle cells in vivo: Evidence of a pressure-independent effect. Clin Exp Pharmacol Physiol 34: 205-209.
10. Castoldi G, Di Gioia CR, Bombardi C, Perego C, Perego L, Mancini M, Leopizzi M, Corradi B, Perlini S, Zerbini G, Stella A. 2010. Prevention of myocardial fibrosis by N-acetyl-seryl-aspartyl-lysyl-proline in diabetic rats. Clin Sci (Lond) 118: 211-220.
11. Cheng Y, Ji R, Yue J, Yang J, Liu X, Chen H, Dean DB, Zhang C. 2007. MicroRNAs are aberrantly expressed in hypertrophic heart: Do they play a role in cardiac hypertrophy? Am J Pathol 170: 1831-1840.
12. Creemers EE, Pinto YM. 2011. Molecular mechanisms that control interstitial fibrosis in the pressure-overloaded heart. Cardiovasc Res 89: 265-272.
13. Da Costa-Martins PA, Salic K, Gladka MM, Armand AS, Leptidis S, El Azzouzi H, Hansen A, Coenen-de Roo CJ, Bierhuizen MF, van der Nagel R, van Kuik J, de Weger R, de Bruin A, Condorelli G, Arbones ML, Eschenhagen T, De Windt LJ. 2010. MicroRNA-199b targets the nuclear kinase Dyrk1a in an auto-amplification loop promoting calcineurin/NFAT signalling. Nat Cell Biol 12: 1220-1227.
14. de Gasparo M, Catt KJ, Inagami T, Wright JW, Unger T. 2000. International union of pharmacology. XXIII. The angiotensin II receptors. Pharmacol Rev 52: 415-472.
15. Desmoulière A, Geinoz A, Gabbiani F, Gabbiani G. 1993. Transforming growth factor-beta 1 induces alpha-smooth muscle actin expression in granulation tissue myofibroblasts and in quiescent and growing cultured fibroblasts. J Cell Biol 122: 103-111.
16. Duisters RF, Tijsen AJ, Schroen B, Leenders JJ, Lentink V, van der Made I, Herias V, van Leeuwen RE, Schellings MW, Barenbrug P, Maessen JG, Heymans S, Pinto YM, Creemers EE. 2009. MiR-133 and miR-30 regulate connective tissue growth factor: Implications for a role of microRNAs in myocardial matrix remodeling. Circ Res 104: 170-178.
17. Dzau VJ. 2001. Tissue angiotensin and pathobiology of vascular disease: A unifying hypothesis. Hypertension 37: 1047-1052.
18. Gao X, He X, Luo B, Peng L, Lin J, Zuo Z. 2009. Angiotensin II increases collagen I expression via transforming growth factor-beta1 and extracellular signal-regulated kinase in cardiac fibroblasts. Eur J Pharmacol 606: 115-120.
19. Infanger M, Grosse J, Westphal K, Leder A, Ulbrich C, Paul M, Grimm D. 2008. Vascular endothelial growth factor induces extracellular matrix proteins and osteopontin in the umbilical artery. Ann Vasc Surg 22: 273-284.
20. Kakkar R, Lee RT. 2010. Intramyocardial fibroblast myocyte communication. Circ Res 106: 47-57.
21. Leask A. 2010. Potential therapeutic targets for cardiac fibrosis: TGFbeta, angiotensin, endothelin, CCN2, and PDGF, partners in fibroblast activation. Circ Res 106: 1675-1680.
22. Liu X, Gai Y, Liu F, Gao W, Zhang Y, Xu M, Li Z. 2010a. Trimetazidine inhibits pressure overload-induced cardiac fibrosis through NADPH oxidase-ROS-CTGF pathway. Cardiovasc Res 88: 150-158.
23. Liu Y, Taylor NE, Lu L, Usa K, Cowley AW, Jr., Ferreri NR, Yeo NC, Liang M. 2010b. Renal medullary microRNAs in Dahl salt-sensitive rats: miR-29b regulates several collagens and related genes. Hypertension 55: 974-982.
24. Matkovich SJ, Wang W, Tu Y, Eschenbacher WH, Dorn LE, Condorelli G, Diwan A, Nerbonne JM, Dorn GW II. 2010. MicroRNA-133a protects against myocardial fibrosis and modulates electrical repolarization without affecting hypertrophy in pressure-overloaded adult hearts. Circ Res 106: 166-175.
25. Maurer B, Stanczyk J, Jüngel A, Akhmetshina A, Trenkmann M, Brock M, Kowal-Bielecka O, Gay RE, Michel BA, Distler JH, Gay S, Distler O. 2010. MicroRNA-29, a key regulator of collagen expression in systemic sclerosis. Arthritis Rheum 62: 1733-1743.
26. Ohnishi H, Oka T, Kusachi S, Nakanishi T, Takeda K, Nakahama M, Doi M, Murakami T, Ninomiya Y, Takigawa M, Tsuji T. 1998. Increased expression of connective tissue growth factor in the infarct zone of experimentally induced myocardial infarction in rats. J Mol Cell Cardiol 30: 2411-2422.
27. Ortiz RM, Kobori H, Conte D, Navar LG. 2010. Angiotensin II-induced reduction in body mass is Ang II receptor mediated in association with elevated corticosterone. Growth Horm IGF Res 20: 282-288.
28. Rompe F, Unger T, Steckelings UM. 2010. The angiotensin AT2 receptor in inflammation. Drug News Perspect 23: 104-111.
29. Schroder D, Heger J, Piper HM, Euler G. 2006. Angiotensin II stimulates apoptosis via TGF-beta1 signaling in ventricular cardiomyocytes of rat. J Mol Med 84: 975-983.
30. Schultz Jel J, Witt SA, Glascock BJ, Nieman ML, Reiser PJ, Nix SL, Kimball TR, Doetschman T. 2002. TGF-beta1 mediates the hypertrophic cardiomyocyte growth induced by angiotensin II. J Clin Invest 109: 787-796.
31. Shan H, Zhang Y, Lu Y, Zhang Y, Pan Z, Cai B, Wang N, Li X, Feng T, Hong Y, Yang B. 2009. Downregulation of miR-133 and miR-590 contributes to nicotine-induced atrial remodelling in canines. Cardiovasc Res 83: 465-472.
32. Silver MA, Pick R, Brilla CG, Jalil JE, Janicki JS, Weber KT. 1990. Reactive and reparative fibrillar collagen remodelling in the hypertrophied rat left ventricle: Two experimental models of myocardial fibrosis. Cardiovasc Res 24: 741-747.
33. Simon G, Abraham G. 1995. Angiotensin II administration as an experimental model of hypertension. In: Laragh JH, Brenner BM, editors. Hypertension: Pathophysiology, diagnosis and management. New York: Raven Press. pp 1423-1435.
34. Stoll M, Steckelings UM, Paul M, Bottari SP, Metzger R, Unger T. 1995. The angiotensin AT2-receptor mediates inhibition of cell proliferation in coronary endothelial cells. J Clin Invest 95: 651-657.
35. Sun Y, Weber KT. 2000. Infarct scar: A dynamic tissue. Cardiovasc Res 46: 250-256.
36. Swynghedauw B. 1999. Molecular mechanisms of myocardial remodeling. Physiol Rev 79: 215-262.
37. Takenaka H, Kihara Y, Iwanaga Y, Onozawa Y, Toyokuni S, Kita T. 2006. Angiotensin II, oxidative stress, and extracellular matrix degradation during transition to LV failure in rats with hypertension. J Mol Cell Cardiol 41: 989-997.
38. Thum T, Gross C, Fiedler J, Fischer T, Kissler S, Bussen M, Galuppo P, Just S, Rottbauer W, Frantz S, Castoldi M, Soutschek J, Koteliansky V, Rosenwald A, Basson MA, Licht JD, Pena JT, Rouhanifard SH, Muckenthaler MU, Tuschl T, Martin GR, Bauersachs J, Engelhardt S. 2008. MicroRNA-21 contributes to myocardial disease by stimulating MAP kinase signalling in fibroblasts. Nature 18: 980-984.
39. Timmermans PB, Wong PC, Chiu AT, Herblin WF, Benfield P, Carini DJ, Lee RJ, Wexler RR, Saye JA, Smith RD. 1993. Angiotensin II receptors and angiotensin II receptor antagonists. Pharmacol Rev 45: 205-251.
40. Van Rooij E, Sutherland LB, Thatcher JE, DiMaio JM, Naseem RH, Marshall WS, Hill JA, Olson EN. 2008. Dysregulation of microRNAs after myocardial infarction reveals a role of miR-29 in cardiac fibrosis. Proc Natl Acad Sci USA 105: 13027-13032.
41. Van Rooij E, Olson EN. 2007. MicroRNAs: Powerful new regulators of heart disease and provocative therapeutic targets. J Clin Invest 117: 2369-2376.
42. Zaidi SH, Huang Q, Momen A, Riazi A, Husain M. 2010. Growth differentiation factor 5 regulates cardiac repair after myocardial infarction. J Am Coll Cardiol 55: 135-143.
43. Zeng Y. 2006. Principles of micro-RNA production and maturation. Oncogene 25: 6156-6162.