메뉴 건너뛰기




Volumn 1, Issue , 2014, Pages 319-329

Quercetin inhibits the cytotoxicity and oxidative stress in liver of rats fed aflatoxin-contaminated diet

Author keywords

Aflatoxin; Cytogenetic; Gene expression; Liver; Oxidative stress; Quercetin

Indexed keywords

AFLATOXIN; ALANINE AMINOTRANSFERASE; ALKALINE PHOSPHATASE; ASPARTATE AMINOTRANSFERASE; CARCINOEMBRYONIC ANTIGEN; CHOLESTEROL; DNA; FAS ANTIGEN; FATTY ACID SYNTHASE; GLUTATHIONE PEROXIDASE; GLYCOGEN; LACTATE DEHYDROGENASE; MALONALDEHYDE; NITROUS OXIDE; QUERCETIN; RNA; SUPEROXIDE DISMUTASE; TRIACYLGLYCEROL; TUMOR NECROSIS FACTOR ALPHA;

EID: 84922710158     PISSN: 22147500     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.toxrep.2014.05.014     Document Type: Article
Times cited : (77)

References (63)
  • 1
    • 79957824855 scopus 로고    scopus 로고
    • Dietary supplementation with whey protein and ginseng extract counteracts the oxidative stress and DNA damage in rats fed aflatoxins-contaminated diet
    • Abdel-Aziem S.H., Hassan A.M., Abdel-Wahhab M.A. Dietary supplementation with whey protein and ginseng extract counteracts the oxidative stress and DNA damage in rats fed aflatoxins-contaminated diet. Mutat. Res. 2011, 723:65-71.
    • (2011) Mutat. Res. , vol.723 , pp. 65-71
    • Abdel-Aziem, S.H.1    Hassan, A.M.2    Abdel-Wahhab, M.A.3
  • 4
    • 84866657315 scopus 로고    scopus 로고
    • Panax ginseng C.A. Meyer extract counteracts the oxidative stress in rats fed multi-mycotoxins-contaminated diet
    • Abdel-Wahhab M.A., Ibrahim A.A., El-Nekeety A.A., Hassan N.S., Mohamed A.A. Panax ginseng C.A. Meyer extract counteracts the oxidative stress in rats fed multi-mycotoxins-contaminated diet. Comun. Sci. 2012, 3(3):143-153.
    • (2012) Comun. Sci. , vol.3 , Issue.3 , pp. 143-153
    • Abdel-Wahhab, M.A.1    Ibrahim, A.A.2    El-Nekeety, A.A.3    Hassan, N.S.4    Mohamed, A.A.5
  • 7
    • 84887731704 scopus 로고    scopus 로고
    • 2+ release flux in intact Jurkat cells
    • 2+ release flux in intact Jurkat cells. Arch. Biochem. Biophys. 2013, 540(1-2):145-159.
    • (2013) Arch. Biochem. Biophys. , vol.540 , Issue.1-2 , pp. 145-159
    • Baranm, I.1    Ganea, C.2
  • 9
    • 55149104161 scopus 로고    scopus 로고
    • Quercetin: potentials in the prevention and therapy of disease
    • Bischoff S.C. Quercetin: potentials in the prevention and therapy of disease. Curr. Opin. Clin. Nutr. Metab. Care 2008, 11:733-740.
    • (2008) Curr. Opin. Clin. Nutr. Metab. Care , vol.11 , pp. 733-740
    • Bischoff, S.C.1
  • 10
    • 43049176634 scopus 로고    scopus 로고
    • Health effects of quercetin: from antioxidant to nutraceutical
    • Boots A.W., Haenen G.R., Bast A. Health effects of quercetin: from antioxidant to nutraceutical. Eur. J. Pharmacol. 2008, 585:325-337.
    • (2008) Eur. J. Pharmacol. , vol.585 , pp. 325-337
    • Boots, A.W.1    Haenen, G.R.2    Bast, A.3
  • 12
    • 33645229181 scopus 로고    scopus 로고
    • Characterization and expression analysis during embryo development of the mouse ortholog of MLL3
    • Brun M.E., Gasca S., Girard C., Bouton K., De Massy B., De Sario A. Characterization and expression analysis during embryo development of the mouse ortholog of MLL3. Gene 2006, 371:25-33.
    • (2006) Gene , vol.371 , pp. 25-33
    • Brun, M.E.1    Gasca, S.2    Girard, C.3    Bouton, K.4    De Massy, B.5    De Sario, A.6
  • 13
    • 6544229829 scopus 로고
    • A study of the conditions and mechanisms of the diphenylamine reaction for the estimation of deoxyribonucleic acid
    • Burton K. A study of the conditions and mechanisms of the diphenylamine reaction for the estimation of deoxyribonucleic acid. Biochem. J 1956, 62:315-323.
    • (1956) Biochem. J , vol.62 , pp. 315-323
    • Burton, K.1
  • 14
    • 0000613334 scopus 로고
    • American Chemical Society, Washington, DC, C.E. Searle (Ed.)
    • Busby W.F., Wogon G.N. Chemical Carcinogenesis 1985, 945-1136. American Chemical Society, Washington, DC. 2nd ed. C.E. Searle (Ed.).
    • (1985) Chemical Carcinogenesis , pp. 945-1136
    • Busby, W.F.1    Wogon, G.N.2
  • 15
    • 0031020195 scopus 로고    scopus 로고
    • Antioxidant and prooxidant behavior of flavonoids: structure-activity relationships
    • Cao G., Sofic E., Prior R.L. Antioxidant and prooxidant behavior of flavonoids: structure-activity relationships. Free Radic. Biol. Med. 1997, 22:749-760.
    • (1997) Free Radic. Biol. Med. , vol.22 , pp. 749-760
    • Cao, G.1    Sofic, E.2    Prior, R.L.3
  • 16
    • 0038424492 scopus 로고    scopus 로고
    • Mycotoxins: risks in plant, animal, and human systems
    • J.L. Richard, G.A. Payne (Eds.)
    • CAST Mycotoxins: risks in plant, animal, and human systems. Council for Agricultural Science and Technology Task Force Report No. 139 2003, ISBN: 1-887383-22-0. J.L. Richard, G.A. Payne (Eds.).
    • (2003) Council for Agricultural Science and Technology Task Force Report No. 139
  • 17
    • 26444594915 scopus 로고    scopus 로고
    • Inhibition of iNOS gene expression by quercetin is mediated by the inhibition of IjB kinase, nuclear factor-kappa B and STAT1, and depends on heme oxygenase-1 induction in mouse BV-2 microglia
    • Chen J.C., Ho F.M., Pei-Dawn L.C., Chen C.P., Jeng K.C., Hsu H.B., Lee S.T., Wen T.W., Lin W.W. Inhibition of iNOS gene expression by quercetin is mediated by the inhibition of IjB kinase, nuclear factor-kappa B and STAT1, and depends on heme oxygenase-1 induction in mouse BV-2 microglia. Eur. J. Pharmacol. 2005, 521:9-20.
    • (2005) Eur. J. Pharmacol. , vol.521 , pp. 9-20
    • Chen, J.C.1    Ho, F.M.2    Pei-Dawn, L.C.3    Chen, C.P.4    Jeng, K.C.5    Hsu, H.B.6    Lee, S.T.7    Wen, T.W.8    Lin, W.W.9
  • 18
    • 77952249785 scopus 로고    scopus 로고
    • Protective effects of quercetin on liver injury induced by ethanol
    • Chen X. Protective effects of quercetin on liver injury induced by ethanol. Pharmacogn. Mag. 2010, 6:135-141.
    • (2010) Pharmacogn. Mag. , vol.6 , pp. 135-141
    • Chen, X.1
  • 21
    • 84896301526 scopus 로고    scopus 로고
    • Antigenotoxic effects of (-)-epigallocatechin-3-gallate (EGCG), quercetin, and rutin on chromium trioxide-induced micronuclei in the polychromatic erythrocytes of mouse peripheral blood
    • Del Carmen García-Rodríguez M., Nicolás-Méndez T., Montaño-Rodríguez A.R., Altamirano-Lozano M.A. Antigenotoxic effects of (-)-epigallocatechin-3-gallate (EGCG), quercetin, and rutin on chromium trioxide-induced micronuclei in the polychromatic erythrocytes of mouse peripheral blood. J. Toxicol. Environ. Health A 2014, 77(6):324-336.
    • (2014) J. Toxicol. Environ. Health A , vol.77 , Issue.6 , pp. 324-336
    • Del Carmen García-Rodríguez, M.1    Nicolás-Méndez, T.2    Montaño-Rodríguez, A.R.3    Altamirano-Lozano, M.A.4
  • 25
    • 79956357870 scopus 로고    scopus 로고
    • Antioxidants properties of Thymus vulgaris oil against aflatoxin-induced oxidative stress on male rats
    • El-Nekeety A.A., Mohamed S.R., Hathout A.S., Hassan N.S., Aly S.A., Abdel-Wahhab M.A. Antioxidants properties of Thymus vulgaris oil against aflatoxin-induced oxidative stress on male rats. Toxicon 2011, 57:984-991.
    • (2011) Toxicon , vol.57 , pp. 984-991
    • El-Nekeety, A.A.1    Mohamed, S.R.2    Hathout, A.S.3    Hassan, N.S.4    Aly, S.A.5    Abdel-Wahhab, M.A.6
  • 27
    • 84858288370 scopus 로고    scopus 로고
    • Modulation of DNA damage and alteration of gene expression during aflatoxicosis via dietary supplementation of Spirulina (Arthrospira) and whey protein concentrate
    • Hassan A.M., Abdel-Aziem S.H., Abdel-Wahhab M.A. Modulation of DNA damage and alteration of gene expression during aflatoxicosis via dietary supplementation of Spirulina (Arthrospira) and whey protein concentrate. Ecotoxicol. Environ. Saf. 2012, 79:294-300.
    • (2012) Ecotoxicol. Environ. Saf. , vol.79 , pp. 294-300
    • Hassan, A.M.1    Abdel-Aziem, S.H.2    Abdel-Wahhab, M.A.3
  • 28
    • 0020854234 scopus 로고
    • Rapid liquid chromatographic determination of aflatoxins in heavily contaminated corn
    • Hustchins J.E., Hagler W.M. Rapid liquid chromatographic determination of aflatoxins in heavily contaminated corn. J. Assoc. Off. Anal. Chem. 1983, 66:1458-1465.
    • (1983) J. Assoc. Off. Anal. Chem. , vol.66 , pp. 1458-1465
    • Hustchins, J.E.1    Hagler, W.M.2
  • 29
    • 63049132131 scopus 로고    scopus 로고
    • Activation of phosphatidylinositol 3-kinase is required for tumor necrosis factor-a-induced upregulation of matrix metalloproteinase-9: its direct inhibition by quercetin
    • Hwang M.K., Song N.R., Kang N.J., Lee K.W., Lee H.J. Activation of phosphatidylinositol 3-kinase is required for tumor necrosis factor-a-induced upregulation of matrix metalloproteinase-9: its direct inhibition by quercetin. Int. J. Biochem. Cell Biol. 2009, 41:1592-1600.
    • (2009) Int. J. Biochem. Cell Biol. , vol.41 , pp. 1592-1600
    • Hwang, M.K.1    Song, N.R.2    Kang, N.J.3    Lee, K.W.4    Lee, H.J.5
  • 30
    • 0000240173 scopus 로고
    • Evaluation of carcinogen risks to humans. Some naturally occurring substances; foods, items and constituents, heterocyclic aromatic amines and mycotoxins
    • IRAC, Lyon, France
    • IARC Evaluation of carcinogen risks to humans. Some naturally occurring substances; foods, items and constituents, heterocyclic aromatic amines and mycotoxins. IRAC Monographs on the Evaluation of Carcinogenic Risks to Humans 1993, vol. 56:243-395. IRAC, Lyon, France.
    • (1993) IRAC Monographs on the Evaluation of Carcinogenic Risks to Humans , vol.56 , pp. 243-395
  • 31
    • 24044471309 scopus 로고    scopus 로고
    • Superoxide dismutases and their impact upon human health
    • Johnson F., Giulivi C. Superoxide dismutases and their impact upon human health. Mol. Aspects Med. 2005, 26:340-352.
    • (2005) Mol. Aspects Med. , vol.26 , pp. 340-352
    • Johnson, F.1    Giulivi, C.2
  • 32
    • 18244415707 scopus 로고    scopus 로고
    • Defenses against peroxynitrite: selenocompounds and flavonoids
    • Klotz L.O., Sies H. Defenses against peroxynitrite: selenocompounds and flavonoids. Toxicol. Lett. 2003, 140:125-132.
    • (2003) Toxicol. Lett. , vol.140 , pp. 125-132
    • Klotz, L.O.1    Sies, H.2
  • 34
    • 0031822018 scopus 로고    scopus 로고
    • Antioxidant and hepatoprotective activity of punicalagin and punicalin on carbon tetrachloride-induced liver damage in rats
    • Lin C.C., Hsu Y.F., Lin T.C., Hsu F.L., Hsu H.Y. Antioxidant and hepatoprotective activity of punicalagin and punicalin on carbon tetrachloride-induced liver damage in rats. J. Pharm. Pharmacol. 1998, 50:789-794.
    • (1998) J. Pharm. Pharmacol. , vol.50 , pp. 789-794
    • Lin, C.C.1    Hsu, Y.F.2    Lin, T.C.3    Hsu, F.L.4    Hsu, H.Y.5
  • 35
    • 76549135006 scopus 로고    scopus 로고
    • Quercetin protects against ethanol-induced oxidative damage in rat primary hepatocytes
    • Liu S., Hou W., Yao P., Zhang B., Sun S., Nussler A.K., Liu L. Quercetin protects against ethanol-induced oxidative damage in rat primary hepatocytes. Toxicol. In Vitro 2010, 24:516-522.
    • (2010) Toxicol. In Vitro , vol.24 , pp. 516-522
    • Liu, S.1    Hou, W.2    Yao, P.3    Zhang, B.4    Sun, S.5    Nussler, A.K.6    Liu, L.7
  • 36
    • 33745377482 scopus 로고    scopus 로고
    • Quercetin reverses d-galactose-induced neurotoxicity in mouse brain
    • Lu J., Zheng Y., Lou L., Wu D., Sun D., Feng Y. Quercetin reverses d-galactose-induced neurotoxicity in mouse brain. Behav. Brain Res. 2006, 171:251-260.
    • (2006) Behav. Brain Res. , vol.171 , pp. 251-260
    • Lu, J.1    Zheng, Y.2    Lou, L.3    Wu, D.4    Sun, D.5    Feng, Y.6
  • 38
    • 0031892263 scopus 로고    scopus 로고
    • Prevention of maternal and developmental toxicity in rats via dietary inclusion of common aflatoxin sorbents: potential for hidden risks
    • Mayura K., Abdel-Wahhab M.A., McKenzie K.S., Sarr A.B., Edwards J.F., Naguib K., Phillips T.D. Prevention of maternal and developmental toxicity in rats via dietary inclusion of common aflatoxin sorbents: potential for hidden risks. Toxicol. Sci. 1998, 41:175-182.
    • (1998) Toxicol. Sci. , vol.41 , pp. 175-182
    • Mayura, K.1    Abdel-Wahhab, M.A.2    McKenzie, K.S.3    Sarr, A.B.4    Edwards, J.F.5    Naguib, K.6    Phillips, T.D.7
  • 39
    • 1542436560 scopus 로고    scopus 로고
    • Quercetin, a flavonoid antioxidant, prevents and protects against ethanol-induced oxidative stress in mouse liver
    • Molina M.F., Sanchez-Reus I., Iglesias I., Benedi J. Quercetin, a flavonoid antioxidant, prevents and protects against ethanol-induced oxidative stress in mouse liver. Biol. Pharm. Bull. 2003, 26:1398-1402.
    • (2003) Biol. Pharm. Bull. , vol.26 , pp. 1398-1402
    • Molina, M.F.1    Sanchez-Reus, I.2    Iglesias, I.3    Benedi, J.4
  • 41
    • 1842421154 scopus 로고    scopus 로고
    • Molecular imaging of the biological effects of quercetin and quercetin-rich foods
    • Moskaug J.O., Carlsen H., Myhrstad M., Blomhoff R. Molecular imaging of the biological effects of quercetin and quercetin-rich foods. Mech. Ageing Dev. 2004, 125:315-324.
    • (2004) Mech. Ageing Dev. , vol.125 , pp. 315-324
    • Moskaug, J.O.1    Carlsen, H.2    Myhrstad, M.3    Blomhoff, R.4
  • 43
    • 0036489186 scopus 로고    scopus 로고
    • Flavonoids increase the intracellular glutathione level by transactivation of the gamma-glutamylcysteine synthetase catalytical subunit promoter
    • Myhrstad M.C., Carlsen H., Nordstrom O., Blomhoff R., Moskaug J.J. Flavonoids increase the intracellular glutathione level by transactivation of the gamma-glutamylcysteine synthetase catalytical subunit promoter. Free Radic. Biol. Med. 2002, 32:386-393.
    • (2002) Free Radic. Biol. Med. , vol.32 , pp. 386-393
    • Myhrstad, M.C.1    Carlsen, H.2    Nordstrom, O.3    Blomhoff, R.4    Moskaug, J.J.5
  • 46
    • 0037403686 scopus 로고    scopus 로고
    • Regulation of CYP3A4 expression in human hepatocytes by pharmaceuticals and natural products
    • Raucy J.L. Regulation of CYP3A4 expression in human hepatocytes by pharmaceuticals and natural products. Drug Metab. Dispos. 2003, 31:533-539.
    • (2003) Drug Metab. Dispos. , vol.31 , pp. 533-539
    • Raucy, J.L.1
  • 47
    • 84885357710 scopus 로고    scopus 로고
    • Antioxidant study of quercetin and their metal complex and determination of stability constant by spectrophotometry method
    • Ravichandran R., Rajendran M., Devapiriam D. Antioxidant study of quercetin and their metal complex and determination of stability constant by spectrophotometry method. Food Chem. 2014, 146:472-478.
    • (2014) Food Chem. , vol.146 , pp. 472-478
    • Ravichandran, R.1    Rajendran, M.2    Devapiriam, D.3
  • 48
    • 78049240344 scopus 로고    scopus 로고
    • 1 in poultry: toxicology, metabolism and prevention
    • 1 in poultry: toxicology, metabolism and prevention. Res. Vet. Sci. 2010, 89:325-331.
    • (2010) Res. Vet. Sci. , vol.89 , pp. 325-331
    • Rawal, S.1    Kim, J.E.2    Coulombe, R.3
  • 51
    • 84891402932 scopus 로고    scopus 로고
    • Quercetin and beta-sitosterol prevent high fat diet induced dyslipidemia and hepatotoxicity in Swiss albino mice
    • Sikder K., Das N., Kesh S.B., Dey S. Quercetin and beta-sitosterol prevent high fat diet induced dyslipidemia and hepatotoxicity in Swiss albino mice. Indian J. Exp. Biol. 2014, 52(1):60-66.
    • (2014) Indian J. Exp. Biol. , vol.52 , Issue.1 , pp. 60-66
    • Sikder, K.1    Das, N.2    Kesh, S.B.3    Dey, S.4
  • 52
    • 84888868221 scopus 로고    scopus 로고
    • A role for glutathione, independent of oxidative stress, in the developmental toxicity of methanol
    • Siu M.T., Shapiro A.M., Wiley M.J., Wells P.G. A role for glutathione, independent of oxidative stress, in the developmental toxicity of methanol. Toxicol. Appl. Pharmacol. 2013, 273(3):508-515.
    • (2013) Toxicol. Appl. Pharmacol. , vol.273 , Issue.3 , pp. 508-515
    • Siu, M.T.1    Shapiro, A.M.2    Wiley, M.J.3    Wells, P.G.4
  • 53
    • 60849083793 scopus 로고    scopus 로고
    • Protective effects of Coriandrum sativum extracts on carbon tetrachloride-induced hepatotoxicity in rats
    • Sreelatha S., Padma P.R., Umadevi M. Protective effects of Coriandrum sativum extracts on carbon tetrachloride-induced hepatotoxicity in rats. Food Chem. Toxicol. 2009, 47:702-708.
    • (2009) Food Chem. Toxicol. , vol.47 , pp. 702-708
    • Sreelatha, S.1    Padma, P.R.2    Umadevi, M.3
  • 55
    • 84896899135 scopus 로고    scopus 로고
    • Comparative effect of pioglitazone, quercetin and hydroxy citric acid on the status of lipid peroxidation and antioxidants in experimental non-alcoholic steatohepatitis
    • Surapaneni K.M., Jainu M. Comparative effect of pioglitazone, quercetin and hydroxy citric acid on the status of lipid peroxidation and antioxidants in experimental non-alcoholic steatohepatitis. J. Physiol. Pharmacol. 2014, 65(1):67-74.
    • (2014) J. Physiol. Pharmacol. , vol.65 , Issue.1 , pp. 67-74
    • Surapaneni, K.M.1    Jainu, M.2
  • 56
    • 84897531892 scopus 로고    scopus 로고
    • Efficient melt stabilization of polyethylene with quercetin, a flavonoid type natural antioxidant
    • Tátraaljai D., Földes E., Pukánszky B. Efficient melt stabilization of polyethylene with quercetin, a flavonoid type natural antioxidant. Polym. Degrad. Stab. 2014, 102:41-48.
    • (2014) Polym. Degrad. Stab. , vol.102 , pp. 41-48
    • Tátraaljai, D.1    Földes, E.2    Pukánszky, B.3
  • 57
    • 0026214002 scopus 로고
    • Calcium channel blocking agents protect against acetaminophen-induced cytotoxicity in rat hepatocytes
    • Thialbut N., Peytavin G., Glaude J.R. Calcium channel blocking agents protect against acetaminophen-induced cytotoxicity in rat hepatocytes. J. Biol. Toxicol. 1991, 6:237-238.
    • (1991) J. Biol. Toxicol. , vol.6 , pp. 237-238
    • Thialbut, N.1    Peytavin, G.2    Glaude, J.R.3
  • 59
    • 72749089881 scopus 로고    scopus 로고
    • Protective effect of quercetin in the regression of ethanol-induced hepatotoxicity
    • Vidhya A., Indira M. Protective effect of quercetin in the regression of ethanol-induced hepatotoxicity. Indian J. Pharm. Sci. 2009, 71:527-532.
    • (2009) Indian J. Pharm. Sci. , vol.71 , pp. 527-532
    • Vidhya, A.1    Indira, M.2
  • 60
    • 84932371517 scopus 로고
    • A Bayes rule for the symmetric multiple comparison problems
    • Waller R.A., Duncan D.B. A Bayes rule for the symmetric multiple comparison problems. J. Am. Stat. Assoc. 1969, 64:1484-1503.
    • (1969) J. Am. Stat. Assoc. , vol.64 , pp. 1484-1503
    • Waller, R.A.1    Duncan, D.B.2
  • 62
    • 16544376533 scopus 로고    scopus 로고
    • Human aflatoxicosis in developing countries: a review of toxicology, exposure, potential health consequences, and interventions
    • Williams J.H., Phillips T.D., Jolly P.E., Stiles J.K., Jolly C.M., Aggarwal D. Human aflatoxicosis in developing countries: a review of toxicology, exposure, potential health consequences, and interventions. Am. J. Clin. Nutr. 2004, 80:1106-1122.
    • (2004) Am. J. Clin. Nutr. , vol.80 , pp. 1106-1122
    • Williams, J.H.1    Phillips, T.D.2    Jolly, P.E.3    Stiles, J.K.4    Jolly, C.M.5    Aggarwal, D.6
  • 63
    • 34347392509 scopus 로고    scopus 로고
    • Quercetin protects human hepatocytes from ethanol-derived oxidative stress by inducing heme oxygenase-1 via the MAPK/Nrf2 pathways
    • Yao P., Nussler A., Liu L., Hao L., Song F., Schirmeier A., Nussler N. Quercetin protects human hepatocytes from ethanol-derived oxidative stress by inducing heme oxygenase-1 via the MAPK/Nrf2 pathways. J. Hepatol. 2007, 47:253-261.
    • (2007) J. Hepatol. , vol.47 , pp. 253-261
    • Yao, P.1    Nussler, A.2    Liu, L.3    Hao, L.4    Song, F.5    Schirmeier, A.6    Nussler, N.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.