메뉴 건너뛰기




Volumn 6, Issue 22, 2010, Pages 135-141

Protective effects of quercetin on liver injury induced by ethanol

Author keywords

Ethanol; Liver injury; Protective effect; Quercetin; Rat

Indexed keywords

ALANINE AMINOTRANSFERASE; ALCOHOL; ASPARTATE AMINOTRANSFERASE; GAMMA GLUTAMYLTRANSFERASE; GLUTATHIONE; INTERLEUKIN 1; INTERLEUKIN 10; INTERLEUKIN 1BETA; INTERLEUKIN 6; INTERLEUKIN 8; MALONALDEHYDE; NITRIC OXIDE; QUERCETIN; TRIACYLGLYCEROL; TUMOR NECROSIS FACTOR ALPHA; VASOPRESSIN;

EID: 77952249785     PISSN: 09731296     EISSN: None     Source Type: Journal    
DOI: 10.4103/0973-1296.62900     Document Type: Article
Times cited : (114)

References (62)
  • 1
    • 0036017170 scopus 로고    scopus 로고
    • Liver disease in alcohol abusers: Clinical perspective
    • Diehl AM. Liver disease in alcohol abusers: clinical perspective. Alcohol 2002;27:7-11.
    • (2002) Alcohol , vol.27 , pp. 7-11
    • Diehl, A.M.1
  • 2
    • 0036433173 scopus 로고    scopus 로고
    • Management of chronic hepatitis B: An overview
    • Esteban R. Management of chronic hepatitis B: An overview. Semin Liver Dis 2002;22:1-6.
    • (2002) Semin Liver Dis , vol.22 , pp. 1-6
    • Esteban, R.1
  • 4
    • 0027533507 scopus 로고
    • Oxygen free radicals and metallothionein
    • Sato M, Bremner I. Oxygen free radicals and metallothionein. Free Radic Biol Med 1993;14:325-337
    • (1993) Free Radic Biol Med , vol.14 , pp. 325-337
    • Sato, M.1    Bremner, I.2
  • 5
    • 0030346350 scopus 로고    scopus 로고
    • Function of metallothionein in the body
    • Floriačzyk B. Function of metallothionein in the body. Postepy Hig Med Dosw 1996;50:375-382 .
    • (1996) Postepy Hig Med Dosw , vol.50 , pp. 375-382
    • Floriačzyk, B.1
  • 8
    • 0037254822 scopus 로고    scopus 로고
    • Zinc supplementation at the time of ethanol exposure ameliorates teratogenicity in mice
    • Carey LC, Coyle P, Philcox JC, Rofe AM. Zinc supplementation at the time of ethanol exposure ameliorates teratogenicity in mice. Alcohol Clin Exp Res 2003;27:107-110
    • (2003) Alcohol Clin Exp Res , vol.27 , pp. 107-110
    • Carey, L.C.1    Coyle, P.2    Philcox, J.C.3    Rofe, A.M.4
  • 9
    • 0342369372 scopus 로고    scopus 로고
    • Kupffer cell inactivation alleviates ethanol-induced steatosis and CYP2E1 induction but not inflammatory responses in rat liver
    • Järveläinen HA, Fang C, Ingelman-Sundberg M, Lukkari TA, Sippel H, Lindros KO. Kupffer cell inactivation alleviates ethanol-induced steatosis and CYP2E1 induction but not inflammatory responses in rat liver. J Hepatol 2000;32:900-910
    • (2000) J Hepatol , vol.32 , pp. 900-910
    • Järveläinen, H.A.1    Fang, C.2    Ingelman-Sundberg, M.3    Lukkari, T.A.4    Sippel, H.5    Lindros, K.O.6
  • 10
    • 0034847310 scopus 로고    scopus 로고
    • Alcoholic liver disease: New insights into mechanisms and preventative strategies
    • Stewart S, Jones D, Day CP. Alcoholic liver disease: New insights into mechanisms and preventative strategies. Trends Mol Med 2001;7:408-413
    • (2001) Trends Mol Med , vol.7 , pp. 408-413
    • Stewart, S.1    Jones, D.2    Day, C.P.3
  • 11
    • 0029384834 scopus 로고
    • Alcohol and endotoxin: Another path to alcoholic liver injury?
    • Schenker S, Bay MK. Alcohol and endotoxin: Another path to alcoholic liver injury? Alcohol Clin Exp Res1995;19:1364-1366
    • (1995) Alcohol Clin Exp Res , vol.19 , pp. 1364-1366
    • Schenker, S.1    Bay, M.K.2
  • 12
    • 0032930763 scopus 로고    scopus 로고
    • Effect of chronic coadministration of endotoxin and ethanol on rat liver pathology and proinflammatory and anti-inflammatory cytokines
    • Järveläinen HA, Fang C, Ingelman-Sundberg M, Lindros KO. Effect of chronic coadministration of endotoxin and ethanol on rat liver pathology and proinflammatory and anti-inflammatory cytokines. Hepatology 1999;29:1503-1510
    • (1999) Hepatology , vol.29 , pp. 1503-1510
    • Järveläinen, H.A.1    Fang, C.2    Ingelman-Sundberg, M.3    Lindros, K.O.4
  • 13
    • 0033373209 scopus 로고    scopus 로고
    • Iron primes hepatic macrophages for NF-kappaB activation in alcoholic liver injury
    • Tsukamoto H, Lin M, Ohata M, Giulivi C, French SW, Brittenham G. Iron primes hepatic macrophages for NF-kappaB activation in alcoholic liver injury. Am J Physiol 1999;277:1240-1250
    • (1999) Am J Physiol , vol.277 , pp. 1240-1250
    • Tsukamoto, H.1    Lin, M.2    Ohata, M.3    Giulivi, C.4    French, S.W.5    Brittenham, G.6
  • 14
    • 0842307101 scopus 로고    scopus 로고
    • Evaluation of hepatoprotective effect of Amalkadi Ghrita against carbon tetrachloride-induced hepatic damage in rats
    • Achliya GS, Wadodkar SG, Dorle AK. Evaluation of hepatoprotective effect of Amalkadi Ghrita against carbon tetrachloride-induced hepatic damage in rats. J Ethnopharmacol 2004;90:229-232
    • (2004) J Ethnopharmacol , vol.90 , pp. 229-232
    • Achliya, G.S.1    Wadodkar, S.G.2    Dorle, A.K.3
  • 15
    • 31344442801 scopus 로고    scopus 로고
    • Hepatoprotective effects of rubiadin; A major constituent of Rubia cordifolia Linn
    • Rao GM, Rao CV, Pushpangadan P, Shirwaikar A. Hepatoprotective effects of rubiadin; A major constituent of Rubia cordifolia Linn. J Ethnopharmacol 2006;103:484-490
    • (2006) J Ethnopharmacol , vol.103 , pp. 484-490
    • Rao, G.M.1    Rao, C.V.2    Pushpangadan, P.3    Shirwaikar, A.4
  • 16
    • 0034676629 scopus 로고    scopus 로고
    • Cytokines in alcoholic and nonalcoholic steatohepatitis
    • Tilg H, Diehl AM. Cytokines in alcoholic and nonalcoholic steatohepatitis. N Engl J Med 2000;3439:1467-1476
    • (2000) N Engl J Med , vol.3439 , pp. 1467-1476
    • Tilg, H.1    Diehl, A.M.2
  • 17
    • 0038275597 scopus 로고    scopus 로고
    • Free radicals and alcohol-induced liver injury
    • Sherman CD, Preedy VR, Watson RR, editors. London: Taylor and Francis
    • Albano E. Free radicals and alcohol-induced liver injury. In: Sherman CD, Preedy VR, Watson RR, editors. Ethanol and the Liver. London: Taylor and Francis; 2002. P. 153-190
    • (2002) Ethanol and the Liver , pp. 153-190
    • Albano, E.1
  • 18
    • 0037371816 scopus 로고    scopus 로고
    • Oxidants and antioxidants in alcohol-induced liver disease
    • Arteel GE. Oxidants and antioxidants in alcohol-induced liver disease. Gastroenterology 2003;124:778-790
    • (2003) Gastroenterology , vol.124 , pp. 778-790
    • Arteel, G.E.1
  • 19
    • 20844450242 scopus 로고    scopus 로고
    • Studies on chemical constituents in herb of Lamium maculatum var. kansuense (II)
    • Deng YR, Ding L, Wu SX, Wang HQ. Studies on chemical constituents in herb of Lamium maculatum var. kansuense (II). Zhongguo Zhong Yao Za Zhi 2005;30:272-274
    • (2005) Zhongguo Zhong Yao Za Zhi , vol.30 , pp. 272-274
    • Deng, Y.R.1    Ding, L.2    Wu, S.X.3    Wang, H.Q.4
  • 20
    • 0033021259 scopus 로고    scopus 로고
    • In vitro Dietary flavonoids protect human colonocyte DNA from oxidative attack
    • Duthie SJ, Dobson VL. In vitro Dietary flavonoids protect human colonocyte DNA from oxidative attack. Eur J Nutr 1999;38:28-34.
    • (1999) Eur J Nutr , vol.38 , pp. 28-34
    • Duthie, S.J.1    Dobson, V.L.2
  • 23
    • 0036296295 scopus 로고    scopus 로고
    • Wine flavonoids protect against LDL oxidation and atherosclerosis
    • Aviram M, Fuhrman B. Wine flavonoids protect against LDL oxidation and atherosclerosis. Ann N Y Acad Sci 2002;957:146-161
    • (2002) Ann N y Acad Sci , vol.957 , pp. 146-161
    • Aviram, M.1    Fuhrman, B.2
  • 24
    • 0033637140 scopus 로고    scopus 로고
    • The effects of plant flavonoids on mammalian cells: Implications for inflammation, heart disease, and cancer
    • Middleton E Jr, Kandaswami C, Theoharides TC. The effects of plant flavonoids on mammalian cells: Implications for inflammation, heart disease, and cancer. Pharmacol Rev 2000;52:673-751.
    • (2000) Pharmacol Rev , vol.52 , pp. 673-751
    • Middleton Jr., E.1    Kandaswami, C.2    Theoharides, T.C.3
  • 25
    • 0036752553 scopus 로고    scopus 로고
    • Natural extracts as possible protective agents of brain aging
    • Bastianetto S, Quirion R. Natural extracts as possible protective agents of brain aging. Neurobiol Aging 2002;23:891-897
    • (2002) Neurobiol Aging , vol.23 , pp. 891-897
    • Bastianetto, S.1    Quirion, R.2
  • 27
    • 0038814267 scopus 로고    scopus 로고
    • Prevention of alterations in intestinal permeability is involved in zinc inhibition of acute ethanol-induced liver damage in mice
    • Lambert JC, Zhou Z, Wang L, Song Z, McClain CJ, Kang YJ. Prevention of alterations in intestinal permeability is involved in zinc inhibition of acute ethanol-induced liver damage in mice. J Pharmacol Exp Ther 2003;305:880-886
    • (2003) J Pharmacol Exp Ther , vol.305 , pp. 880-886
    • Lambert, J.C.1    Zhou, Z.2    Wang, L.3    Song, Z.4    McClain, C.J.5    Kang, Y.J.6
  • 28
    • 0036083963 scopus 로고    scopus 로고
    • Metallothionein-independent zinc protection from alcoholic liver injury
    • Zhou Z, Sun X, Lambert JC, Saari JT, Kang YJ. Metallothionein-independent zinc protection from alcoholic liver injury. Am J Pathol 2002;160:2267-2274
    • (2002) Am J Pathol , vol.160 , pp. 2267-2274
    • Zhou, Z.1    Sun, X.2    Lambert, J.C.3    Saari, J.T.4    Kang, Y.J.5
  • 30
    • 0022742360 scopus 로고
    • IFCC methods for the measurement of catalytic concentration of enzymes. Part 3. IFCC method for alanine aminotransferase
    • International federation of clinical chemistry. Scientific committee. Expert panel on enzymes. IFCC document stage 2, draft 1; 1979-11-19 with a view to an IFCC recommendation
    • Bergmeyer HU International federation of clinical chemistry. Scientific committee. Expert panel on enzymes. IFCC document stage 2, draft 1; 1979-11-19 with a view to an IFCC recommendation. IFCC methods for the measurement of catalytic concentration of enzymes. Part 3. IFCC method for alanine aminotransferase. J Clin Chem Clin Biochem 1986;7:481-495
    • (1986) J Clin Chem Clin Biochem , vol.7 , pp. 481-495
    • Bergmeyer, H.U.1
  • 33
    • 0014356266 scopus 로고
    • Hydrogen peroxide detoxication by glutathione peroxidase and catalase in rat liver homogenates
    • Hochstein P, Utley H. Hydrogen peroxide detoxication by glutathione peroxidase and catalase in rat liver homogenates. Mol Pharmacol 1968;4:574-579
    • (1968) Mol Pharmacol , vol.4 , pp. 574-579
    • Hochstein, P.1    Utley, H.2
  • 34
    • 0018384650 scopus 로고
    • Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction
    • Ohkawa H, Ohishi N, Yagi K. Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction. Anal Biochem 1979;95:351-358
    • (1979) Anal Biochem , vol.95 , pp. 351-358
    • Ohkawa, H.1    Ohishi, N.2    Yagi, K.3
  • 35
    • 0037052685 scopus 로고    scopus 로고
    • Mediation by nitric oxide of the stimulatory effects of ethanol on blood flow
    • Baraona E, Shoichet L, Navder K, Lieber CS. Mediation by nitric oxide of the stimulatory effects of ethanol on blood flow. Life Sci 2002;70:2987-2995
    • (2002) Life Sci , vol.70 , pp. 2987-2995
    • Baraona, E.1    Shoichet, L.2    Navder, K.3    Lieber, C.S.4
  • 36
    • 0024587645 scopus 로고
    • Increased tumor necrosis factor production by monocytes in alcoholic hepatitis
    • McClain CJ, Cohen DA. Increased tumor necrosis factor production by monocytes in alcoholic hepatitis. Hepatology 1989;9:349-351
    • (1989) Hepatology , vol.9 , pp. 349-351
    • McClain, C.J.1    Cohen, D.A.2
  • 37
    • 0025270685 scopus 로고
    • Excessive in vitro bacterial lipopolysaccharide-induced production of monokines in cirrhosis
    • Devière J, Content J, Denys C, Vandenbussche P, Schandene L, Wybran J, et al. Excessive in vitro bacterial lipopolysaccharide-induced production of monokines in cirrhosis. Hepatology 1990;11:628-634
    • (1990) Hepatology , vol.11 , pp. 628-634
    • Devière, J.1    Content, J.2    Denys, C.3    Vandenbussche, P.4    Schandene, L.5    Wybran, J.6
  • 38
    • 0024312875 scopus 로고
    • High interleukin-6 serum levels and increased production by leucocytes in alcoholic liver cirrhosis. Correlation with IgA serum levels and lymphokines production
    • Deviere J, Content J, Denys C, Vandenbussche P, Schandene L, Wybran J, et al. High interleukin-6 serum levels and increased production by leucocytes in alcoholic liver cirrhosis. Correlation with IgA serum levels and lymphokines production. Clin Exp Immunol 1989;77:221-225
    • (1989) Clin Exp Immunol , vol.77 , pp. 221-225
    • Deviere, J.1    Content, J.2    Denys, C.3    Vandenbussche, P.4    Schandene, L.5    Wybran, J.6
  • 40
    • 0027294661 scopus 로고
    • Circulating and tissue levels of the neutrophil chemotaxin interleukin-8 are elevated in severe acute alcoholic hepatitis, and tissue levels correlate with neutrophil infiltration
    • Sheron N, Bird G, Koskinas J, Portmann B, Ceska M, Lindley I. Circulating and tissue levels of the neutrophil chemotaxin interleukin-8 are elevated in severe acute alcoholic hepatitis, and tissue levels correlate with neutrophil infiltration. Hepatology 1993;18:41-46
    • (1993) Hepatology , vol.18 , pp. 41-46
    • Sheron, N.1    Bird, G.2    Koskinas, J.3    Portmann, B.4    Ceska, M.5    Lindley, I.6
  • 41
    • 0027296643 scopus 로고
    • Increased plasma interleukin-8 concentrations in alcoholic hepatitis
    • Hill DB, Marsano LS, McClain CJ. Increased plasma interleukin-8 concentrations in alcoholic hepatitis. Hepatology 1993;18:576-580
    • (1993) Hepatology , vol.18 , pp. 576-580
    • Hill, D.B.1    Marsano, L.S.2    McClain, C.J.3
  • 43
    • 0032185432 scopus 로고    scopus 로고
    • Alcoholic liver injury involves activation of Kupffer cells by endotoxin
    • Thurman RG. Alcoholic liver injury involves activation of Kupffer cells by endotoxin Am J Physiol 1998;275:605-611
    • (1998) Am J Physiol , vol.275 , pp. 605-611
    • Thurman, R.G.1
  • 46
    • 0026741759 scopus 로고
    • Overproduction of nitric oxide in cytokine-mediated and septic shock
    • Kilbourn RG, Griffith OW. Overproduction of nitric oxide in cytokine-mediated and septic shock. J Natl Cancer Inst 1992;84:827-831
    • (1992) J Natl Cancer Inst , vol.84 , pp. 827-831
    • Kilbourn, R.G.1    Griffith, O.W.2
  • 47
    • 23644437708 scopus 로고    scopus 로고
    • TNF-alpha as a promising therapeutic target in chronic asthma: A lesson from rheumatoid arthritis
    • Russo C, Polosa R. TNF-alpha as a promising therapeutic target in chronic asthma: A lesson from rheumatoid arthritis. Clin Sci 2005;109:135-142
    • (2005) Clin Sci , vol.109 , pp. 135-142
    • Russo, C.1    Polosa, R.2
  • 48
    • 0028236896 scopus 로고
    • Use of reverse transcription-polymerase chain reaction to evaluate in vivo cytokine gene expression in rats fed ethanol for long periods
    • Nanji AA, Zhao S, Sadrzadeh SM, Waxman DJ. Use of reverse transcription-polymerase chain reaction to evaluate in vivo cytokine gene expression in rats fed ethanol for long periods. Hepatology 1994;19:1483-1487
    • (1994) Hepatology , vol.19 , pp. 1483-1487
    • Nanji, A.A.1    Zhao, S.2    Sadrzadeh, S.M.3    Waxman, D.J.4
  • 50
    • 0025225649 scopus 로고
    • Involvement of tumor necrosis factor-alpha in development of hepatic injury in galactosamine-sensitized mice
    • Hishinuma I, Nagakawa J, Hirota K, Miyamoto K, Tsukidate K, Yamanaka T, et al. Involvement of tumor necrosis factor-alpha in development of hepatic injury in galactosamine-sensitized mice. Hepatology 1990;12:1187-1191
    • (1990) Hepatology , vol.12 , pp. 1187-1191
    • Hishinuma, I.1    Nagakawa, J.2    Hirota, K.3    Miyamoto, K.4    Tsukidate, K.5    Yamanaka, T.6
  • 51
    • 0027375335 scopus 로고
    • Serum malondialdehyde and mitochondrial aspartate aminotransferase activity as markers of chronic alcohol intake and alcoholic liver disease
    • Baldi E, Burra P, Plebani M, Salvagnini M. Serum malondialdehyde and mitochondrial aspartate aminotransferase activity as markers of chronic alcohol intake and alcoholic liver disease. Ital J Gastroenterol 1993;25:429-432
    • (1993) Ital J Gastroenterol , vol.25 , pp. 429-432
    • Baldi, E.1    Burra, P.2    Plebani, M.3    Salvagnini, M.4
  • 52
    • 0013688141 scopus 로고
    • Serum enzyme changes as evidence of liver reaction to oral alcohol
    • Goldberg DM, Watts C. Serum enzyme changes as evidence of liver reaction to oral alcohol. Gastroenterology 1965;49:256-261
    • (1965) Gastroenterology , vol.49 , pp. 256-261
    • Goldberg, D.M.1    Watts, C.2
  • 53
    • 0033568661 scopus 로고    scopus 로고
    • Repression of gene expression by oxidative stress
    • Morel Y, Barouki R. Repression of gene expression by oxidative stress. Biochem J 1999;342:481-496
    • (1999) Biochem J , vol.342 , pp. 481-496
    • Morel, Y.1    Barouki, R.2
  • 55
    • 0034019069 scopus 로고    scopus 로고
    • Regulation of manganese superoxide dismutase (MnSOD) in chronic experimental alcoholism: Effects of vitamin E-supplemented and -deficient diets
    • Koch O, Farré S, De Leo ME, Palozza P, Palazzotti B, Borrelo S, et al. Regulation of manganese superoxide dismutase (MnSOD) in chronic experimental alcoholism: Effects of vitamin E-supplemented and -deficient diets. Alcohol Alcohol 2000;35:159-163
    • (2000) Alcohol Alcohol , vol.35 , pp. 159-163
    • Koch, O.1    Farré, S.2    De Leo, M.E.3    Palozza, P.4    Palazzotti, B.5    Borrelo, S.6
  • 56
    • 0021763962 scopus 로고
    • Free-radical mechanisms in tissue injury
    • Slater TF. Free-radical mechanisms in tissue injury. Biochem J 1984;222:1.
    • (1984) Biochem J , vol.222 , pp. 1
    • Slater, T.F.1
  • 57
    • 0025142672 scopus 로고
    • Malondialdehyde determination as index of lipid peroxidation
    • Draper HH, Hadley M. Malondialdehyde determination as index of lipid peroxidation. Met Enzymol 1990;186:421-431
    • (1990) Met Enzymol , vol.186 , pp. 421-431
    • Draper, H.H.1    Hadley, M.2
  • 58
    • 0018883268 scopus 로고
    • Influence of prolonged ethanol intake on the levels and turnover of alcohol and aldehyde dehydrogenases and glutathione
    • Guerri C, Grisolia S. Influence of prolonged ethanol intake on the levels and turnover of alcohol and aldehyde dehydrogenases and glutathione. Adv Exp Med Biol 1980;126:365-384
    • (1980) Adv Exp Med Biol , vol.126 , pp. 365-384
    • Guerri, C.1    Grisolia, S.2
  • 59
    • 0018819489 scopus 로고
    • Modulation of alcohol dehydrogenase and ethanol metabolism by sex hormones in the spontaneously hypertensive rat. Effect of chronic ethanol administration
    • Rachamin G, MacDonald JA, Wahid S, Clapp JJ, Khanna JM, Israel Y. Modulation of alcohol dehydrogenase and ethanol metabolism by sex hormones in the spontaneously hypertensive rat. Effect of chronic ethanol administration. Biochem J 1980;186:483-490
    • (1980) Biochem J , vol.186 , pp. 483-490
    • Rachamin, G.1    MacDonald, J.A.2    Wahid, S.3    Clapp, J.J.4    Khanna, J.M.5    Israel, Y.6
  • 60
    • 0021251601 scopus 로고
    • Kinetics of inhibition of ethanol metabolism in rats and the rate-limiting role of alcohol dehydrogenase
    • Plapp BV, Leidal KG, Smith RK, Murch BP. Kinetics of inhibition of ethanol metabolism in rats and the rate-limiting role of alcohol dehydrogenase. Arch Biochem Biophys 1984;230:30-38
    • (1984) Arch Biochem Biophys , vol.230 , pp. 30-38
    • Plapp, B.V.1    Leidal, K.G.2    Smith, R.K.3    Murch, B.P.4
  • 62
    • 32044456970 scopus 로고    scopus 로고
    • Glycoprotein isolated from Acanthopanax senticosus protects against hepatotoxicity induced by acute and chronic alcohol treatment
    • Choi JS, Yoon TJ, Kang KR, Lee KH, Kim WH, Suh YH, et al. Glycoprotein isolated from Acanthopanax senticosus protects against hepatotoxicity induced by acute and chronic alcohol treatment. Biol Pharm Bull 2006;29:306-314
    • (2006) Biol Pharm Bull , vol.29 , pp. 306-314
    • Choi, J.S.1    Yoon, T.J.2    Kang, K.R.3    Lee, K.H.4    Kim, W.H.5    Suh, Y.H.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.