Azelnidipine is a calcium blocker that attenuates liver fibrosis and may increase antioxidant defence

British Journal of Pharmacology

Volumn 165, Issue 4 B, 2012, Pages 1173-1187

  Ohyama, T ^a   Sato, K ^a   Kishimoto, K ^a   Yamazaki, Y ^a   Horiguchi, N ^a   Ichikawa, T ^a   Kakizaki, S ^a   Takagi, H ^a   Izumi, T ^a   Mori, M ^a  

^a GUNMA UNIVERSITY   (Japan)

Author keywords

carbon tetrachloride; LX 2; reactive oxygen species; signal transduction; thioacetamide

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; AMLODIPINE; ANGIOTENSIN II; ANTHRA[1,9 CD]PYRAZOL 6(2H) ONE; AZELNIDIPINE; CALCIUM CHANNEL BLOCKING AGENT; CARBON TETRACHLORIDE; COLLAGEN TYPE 1; DILTIAZEM; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE P38; NIFEDIPINE; NITRENDIPINE; STRESS ACTIVATED PROTEIN KINASE; THIOACETAMIDE; TRANSFORMING GROWTH FACTOR BETA1; VERAPAMIL;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; CELL ACTIVATION; CELL INFILTRATION; CELL LINE; CONTROLLED STUDY; DNA DAMAGE; DRUG EFFECT; DRUG MECHANISM; ENZYME PHOSPHORYLATION; HUMAN; HUMAN CELL; IN VITRO STUDY; INFLAMMATORY CELL; LIPID PEROXIDATION; LIVER FIBROSIS; MOUSE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; REMISSION; STELLATE CELL;

ANGIOTENSIN II; ANIMALS; ANTIOXIDANTS; AZETIDINECARBOXYLIC ACID; CALCIUM; CALCIUM CHANNEL BLOCKERS; CARBON TETRACHLORIDE; CELL LINE; CELL SURVIVAL; COLLAGEN TYPE I; DIHYDROPYRIDINES; DISEASE MODELS, ANIMAL; GENE EXPRESSION REGULATION; HUMANS; LIVER CIRRHOSIS; MALE; MICE; MICE, INBRED C57BL; REACTIVE OXYGEN SPECIES; RNA, MESSENGER; THIOACETAMIDE; TRANSFORMING GROWTH FACTOR BETA1;

EID: 84863075934     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1111/j.1476-5381.2011.01599.x     Document Type: Article

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