Phytochemical screening, anticancer and antioxidant activities of Origanum vulgare L. ssp. viride (Boiss.) Hayek, a plant of traditional usage

Journal of the Science of Food and Agriculture

Volumn 95, Issue 4, 2015, Pages 786-798

  Koldaş, Serkan ^a   Demirtas, Ibrahim ^a   Ozen, Tevfik ^b   Demirci, Mehmet Ali ^a   Behçet, Lütfi ^c  

^a CANKIRI KARATEKIN UNIVERSITY   (Turkey)

^b ONDOKUZ MAYIS UNIVERSITY   (Turkey)

^c BINGOL UNIVERSITY   (Turkey)

Author keywords

Antioxidant; Antiproliferative; Origanum acutidens; Origanum vulgare ssp. viride; Phenolics

Indexed keywords

ORIGANUM; ORIGANUM VULGARE;

ANTINEOPLASTIC AGENT; ANTIOXIDANT; CARYOPHYLLENE; CINEOLE; CYCLOHEXANOL DERIVATIVE; ESSENTIAL OIL; PHENOL DERIVATIVE; PLANT EXTRACT; SABINENE; SESQUITERPENE; TERPENE; VOLATILE ORGANIC COMPOUND;

CELL PROLIFERATION; CHEMICAL STRUCTURE; CHEMISTRY; DRUG DEVELOPMENT; DRUG EFFECTS; ETHNOPHARMACOLOGY; FLOWER; GROWTH, DEVELOPMENT AND AGING; HELA CELL LINE; HUMAN; ISOLATION AND PURIFICATION; ORIGANUM; PLANT; TRADITIONAL MEDICINE; TURKEY;

ANTINEOPLASTIC AGENTS, PHYTOGENIC; ANTIOXIDANTS; CELL PROLIFERATION; CYCLOHEXANOLS; DRUG DISCOVERY; ETHNOPHARMACOLOGY; FLOWERS; HELA CELLS; HUMANS; MEDICINE, TRADITIONAL; MOLECULAR STRUCTURE; MONOTERPENES; OILS, VOLATILE; ORIGANUM; PHENOLS; PLANT COMPONENTS, AERIAL; PLANT EXTRACTS; SESQUITERPENES; TURKEY; VOLATILE ORGANIC COMPOUNDS;

EID: 84922378210     PISSN: 00225142     EISSN: 10970010     Source Type: Journal    
DOI: 10.1002/jsfa.6903     Document Type: Article

References (52)

1. Souza ELd, Stamford TLM and Lima EdO, Sensitivity of spoiling and pathogen food-related bacteria to Origanum vulgare L. (Lamiaceae) essential oil. Braz J Microbiol 37:527-532 (2006).
2. Mechergui K, Coelho JA, Serra MC, Lamine SB, Boukhchina S and Khouja ML, Essential oils of Origanum vulgare L. subsp. glandulosum (Desf.) Ietswaart from Tunisia: chemical composition and antioxidant activity. J. Sci Food Agric 90:1745-1749 (2010).
3. Cozzi R, Ricordy R, Aglitti T, Gatta V, Perticone P and De Salvia R, Ascorbic acid and beta-carotene as modulators of oxidative damage. Carcinogenesis 18:223-228 (1997).
4. Perera MGAN, Soysa SSSBDP, Abeytunga DTU and Ramesh R, Antioxidant and cytotoxic properties of three traditional decoctions used for the treatment of cancer in Sri Lanka. Pharmacogn Mag 4:172-181 (2008).
5. Hung TM, Na M, Thuong PT, Su ND, Sok D, Song KS, et al., Antioxidant activity of caffeoyl quinic acid derivatives from the roots of Dipsacus asper Wall. J Ethnopharmacol 108:188-192 (2006).
6. Kulisic T, Radonic A, Katalinic V and Milos M, Use of different methods for testing antioxidative activity of oregano essential oil. Food Chem 85:633-640 (2004).
7. Sivropoulou A, Papanikolaou E, Nikolaou C, Kokkini S, Lanaras T and Arsenakis M, Antimicrobial and cytotoxic activities of Origanum essential oils. J Agric Food Chem 44:1202-1205 (1996).
8. Demirtas I, Gecibesler IH and Sahin Yaglioglu A, Antiproliferative activities of isolated flavone glycosides and fatty acids from Stachys byzantina. Phytochem Lett 6:209-214 (2013).
9. Rice-Evans C, Miller N and Paganga G, Antioxidant properties of phenolic compounds. Trends Plant Sci 2:152-159 (1997).
10. Soobrattee MA, Neergheen VS, Luximon-Ramma A, Aruoma OI and Bahorun T, Phenolics as potential antioxidant therapeutic agents: mechanism and actions. Mutat Res Fund Mol Mech Mutagen 579:200-213 (2005).
11. Surh Y-J, Molecular mechanisms of chemopreventive effects of selected dietary and medicinal phenolic substances. Mutat Res Fund Mol Mech Mutagen 428:305-327 (1999).
12. Danila AO, Gatea F and Radu GL, Polyphenol composition and antioxidant activity of selected medicinal herbs. Chem Nat Comp 47:22-26 (2011).
13. Kouri G, Tsimogiannis D, Bardouki H and Oreopoulou V, Extraction and analysis of antioxidant components from Origanum dictamnus. Innovat Food Sci Emerg Technol 8:155-162 (2007).
14. Martins N, Barros L, Santos-Buelga C, Henriques M, Silva S and Ferreira IC, Decoction, infusion and hydroalcoholic extract of Origanum vulgare L.: different performances regarding bioactivity and phenolic compounds. Food Chem 158:73-80 (2014).
15. Berrington D and Lall N, Anticancer activity of certain herbs and spices on the cervical epithelial carcinoma (HeLa) cell line. Evid Based Compl Altern Med 2012:564927 (2012).
16. Asuming WA, Beauchamp PS, Descalzo JT, Dev BC, Dev V, Frost S, et al., Essential oil composition of four Lomatium Raf. species and their chemotaxonomy. Biochem Syst Ecol 33:17-26 (2005).
17. Saroglou V, Dorizas N, Kypriotakis Z and Skaltsa HD, Analysis of the essential oil composition of eight Anthemis species from Greece. J Chromatogr A 1104:313-322 (2006).
18. Roussis V, Tsoukatou M, Petrakis PV, Ioanna C, Skoula M and Harborne JB, Volatile constituents of four Helichrysum species growing in Greece. Biochem Syst Ecol 28:163-175 (2000).
19. Singleton VL and Rossi JA, Colorimetry of total phenolics with phosphomolybdic-phosphotungstic acid reagents. Am J Enol Vitic 16:144-158 (1965).
20. Chang CC, Yang MH, Wen HM and Chern JC, Estimation of total flavonoid content in propolis by two complementary colorimetric methods. J Food Drug Anal 10:178-182 (2002).
21. Prieto P, Pineda M and Aguilar M, Spectrophotometric quantitation of antioxidant capacity through the formation of a phosphomolybdenum complex: specific application to the determination of vitamin E. Anal Biochem 269:337-341 (1999).
22. Choi CW, Kim SC, Hwang SS, Choi BK, Ahn HJ, Lee MY, et al., Antioxidant activity and free radical scavenging capacity between Korean medicinal plants and flavonoids by assay-guided comparison. Plant Sci 163:1161-1168 (2002).
23. Ozen T, Darcan C, Aktop O and Turkekul I, Screening of antioxidant, antimicrobial activities and chemical contents of edible mushrooms wildly grown in the Black Sea region of Turkey. Combinat Chem High Throughput Screening 14:72-84 (2011).
24. Ozen T, Demirtas I and Aksit H, Determination of antioxidant activities of various extracts and essential oil compositions of Thymus praecox subsp. skorpilii var. skorpilii Food Chem 124:58-64 (2011).
25. Oyaizu M, Studies on products of browning reaction. Antioxidative activities of products of browning reaction prepared from glucosamine. Jpn J Nutr Dietet 44:307-315 (1986).
26. Dinis T, Maderia V and Almeida LM, Action of phenolic derivatives (acetaminophen, salicylate, and 5-aminosalicylate) as inhibitors of membrane lipid peroxidation and as peroxyl radical scavengers. Arch Biochem Biophys 315:161-169 (1994).
27. Özen T, Antioxidant activity of wild edible plants in the Black Sea region of Turkey. Grasas Aceites 61:86-94 (2010).
28. Nishikimi M, Appaji Rao N and Yagi K, The occurrence of superoxide anion in the reaction of reduced phenazine methosulfate and molecular oxygen. Biochem Biophys Res Commun 46:849-854 (1972).
29. Blois MS, Antioxidant determinations by the use of a stable free radical. Nature 181:1199-1200 (1958).
30. Özen T and Taş M, Screening and evaluation of antioxidant activity of some amido-carbonyl oxime derivatives and their radical scavenging activities. J Enzyme Inhib Med Chem 24:1141-1147 (2009).
31. Demirtas I, Erenler R, Elmastas M and Goktasoglu A, Studies on the antioxidant potential of flavones of Allium vineale isolated from its water-soluble fraction. Food Chem 136:34-40 (2013).
32. Zhao G-R, Xiang Z-J, Ye T-X, Yuan Y-J and Guo Z-X, Antioxidant activities of Salvia miltiorrhiza and Panax notoginseng. Food Chem 99:767-774 (2006).
33. Urcan E, Haertel U, Styllou M, Hickel R, Scherthan H and Reichl FX, Real-time xCELLigence impedance analysis of the cytotoxicity of dental composite components on human gingival fibroblasts. Dent Mater 26:51-58 (2010).
34. Işik S, Karagöz A, Karaman Ş and Nergiz C, Proliferative and apoptotic effects of olive extracts on cell lines and healthy human cells. Food Chem 134:29-36 (2012).
35. Gülçin I˙, Elmastaş M and Aboul-Enein HY, Antioxidant activity of clove oil - a powerful antioxidant source. Arab J Chem 5:489-499 (2012).
36. Şahin F, Güllüce M, Daferera D, Sökmen A, Sökmen M, Polissiou M, et al., Biological activities of the essential oils and methanol extract of Origanum vulgare ssp. vulgare in the Eastern Anatolia region of Turkey. Food Control 15:549-557 (2004).
37. Afsharypour S, Sajjadi SE and Erfan-Manesh M, Volatile constituents of Origanum vulgare ssp. viride (syn. O. heracleoticum) from Iran. Planta Med 63:179-180 (1997).
38. Potterat O, Antioxidants and free radical scavengers of natural origin. Curr Org Chem 1:415-440 (1997).
39. Meir S, Kanner J, Akiri B and Philosoph-Hadas S, Determination and involvement of aqueous reducing compounds in oxidative defense systems of various senescing leaves. J Agric Food Chem 43:1813-1819 (1995).
40. Halliwell B, The biological toxicity of free radicals and other reactive oxygen species, in Free Radicals and Food Additives, ed. by Halliwell B. Taylor and Francis, London, pp. 37-57 (1991).
41. Dix TA and Aikens J, Mechanisms and biological relevance of lipid peroxidation initiation. Chem Res Toxicol 6:2-18 (1993).
42. Yamaguchi F, Ariga T, Yoshimira Y and Nakazawa H, Antioxidant and anti-glycation of carcinol from Garcinia indica fruit rind. J Agric Food Chem 48:180-185 (2000).
43. Spencer JP, Jenner A, Aruoma OI, Cross CE, Wu R and Halliwell B, Oxidative DNA damage in human respiratory tract epithelial cells. Time course in relation to DNA strand breakage. Biochem Biophys Res Commun 224:17-22 (1996).
44. Hossain MB, Barry-Ryan C, Martin-Diana AB and Brunton NP, Optimisation of accelerated solvent extraction of antioxidant compounds from rosemary (Rosmarinus officinalis L.), marjoram (Origanum majorana L.) and oregano (Origanum vulgare L.) using response surface methodology. Food Chem 126:339-346 (2011).
45. Yesil-Celiktas O, Sevimli C, Bedir E and Vardar-Sukan F, Inhibitory effects of rosemary extracts, carnosic acid and rosmarinic acid on the growth of various human cancer cell lines. Plant Foods Hum Nutr 65:158-163 (2010).
46. Tepe B, Eminagaoglu O, Akpulat HA and Aydin E, Antioxidant potentials and rosmarinic acid levels of the methanolic extracts of Salvia verticillata (L.) subsp. verticillata and S. verticillata (L.) subsp. amasiaca (Freyn & Bornm.) Bornm. Food Chem 100:985-989 (2007).
47. Petersen M and Simmonds MSJ, Rosmarinic acid. Phytochemistry 62:121-125 (2003).
48. Yoshida M, Fuchigami M, Nagao T, Okabe H, Matsunaga K, Takata J, et al., Antiproliferative constituents from Umbelliferae plants. VII. Active triterpenes and rosmarinic acid from Centella asiatica. Biol Pharmaceut Bull 28:173-175 (2005).
49. Demirtas I and Sahin A, Bioactive volatile content of the stem and root of Centaurea carduiformis DC. subsp. carduiformis var. carduiformis. J Chem 2013:1-6 (2013).
50. Demirtas I, Ayhan B, Sahin A, Aksit H, Elmastas M and Telci I, Antioxidant activity and chemical composition of Sideritis libanotica Labill. ssp. linearis (Bentham) Borm. (Lamiaceae). Nat Prod Res 25:1512-1523 (2011).
51. Demirtas I, Sahin A, Ayhan B, Tekin S and Telci I, Antiproliferative effects of the methanolic extracts of Sideritis libanotica Labill. subsp. linearis. Rec Nat Prod 3:104-109 (2009).
52. Yaglioglu AS, Akdulum B, Erenler R, Demirtas I, Telci I and Tekin S, Antiproliferative activity of pentadeca-(8E, 13Z) dien-11-yn-2-one and (E)-1, 8-pentadecadiene from Echinacea pallida (Nutt.) Nutt. roots. Med Chem Res 22:2946-2953 (2013).