Salinomycin and other polyether ionophores are a new class of antiscarring agent

Journal of Biological Chemistry

Volumn 290, Issue 6, 2015, Pages 3563-3575

  Woeller, Collynn F ^a   O'Loughlin, Charles W ^a   Roztocil, Elisa ^a   Feldon, Steven E ^a   Phipps, Richard P ^a  

^a UNIVERSITY OF ROCHESTER SCHOOL OF MEDICINE AND DENTISTRY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL CULTURE; CELL SIGNALING; ETHERS;

EFFECTIVE THERAPY; FIBROBLAST PROLIFERATION; MYOFIBROBLASTS; POLYETHER IONOPHORES; SALINOMYCIN; SCAR FORMATION;

IONOPHORES;

ALPHA SMOOTH MUSCLE ACTIN; ANTISCARRING AGENT; CALPONIN; CLIOQUINOL; COLLAGEN; DERMATOLOGICAL AGENT; LUCIFERASE; MITOGEN ACTIVATED PROTEIN KINASE KINASE 6; MITOGEN ACTIVATED PROTEIN KINASE P38; MONENSIN; NARASIN; POLYETHER IONOPHORE DERIVATIVE; SALINOMYCIN; SB 43152; SMAD2 PROTEIN; SYNAPTOPHYSIN; TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTOR BETA ACTIVATED KINASE 1; UNCLASSIFIED DRUG; ACTA2 PROTEIN, HUMAN; ACTIN; ACTIN BINDING PROTEIN; CALCIUM BINDING PROTEIN; MAP KINASE KINASE KINASE 7; MITOGEN ACTIVATED PROTEIN KINASE KINASE KINASE; MOLECULAR LIBRARY; PYRAN DERIVATIVE;

ANTISCARRING ACTIVITY; ARTICLE; CELL DEATH; CELL PROLIFERATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG ACTIVITY; DRUG POTENCY; DRUG STRUCTURE; DRUG TARGETING; ENZYME ACTIVITY; FIBROBLAST; FIBROSIS; HUMAN; HUMAN CELL; MYOFIBROBLAST; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PROTEIN TARGETING; SCAR; SIGNAL TRANSDUCTION; STRUCTURE ANALYSIS; CELL CULTURE; DRUG EFFECTS; GENETICS; HEK293 CELL LINE; METABOLISM; MOLECULAR LIBRARY; PHARMACOLOGY; PHYSIOLOGY; WOUND HEALING;

ACTINS; CALCIUM-BINDING PROTEINS; CELL PROLIFERATION; CELLS, CULTURED; COLLAGEN; HEK293 CELLS; HUMANS; MAP KINASE KINASE KINASES; MAP KINASE SIGNALING SYSTEM; MICROFILAMENT PROTEINS; MYOFIBROBLASTS; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PYRANS; SMALL MOLECULE LIBRARIES; TRANSFORMING GROWTH FACTOR BETA; WOUND HEALING;

EID: 84922357604     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M114.601872     Document Type: Article

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