Regulation of myofibroblast differentiation by convergence of the Wnt and TGF-β1/Smad signaling pathways

Journal of Molecular and Cellular Cardiology

Volumn 46, Issue 5, 2009, Pages 610-611

  George, Sarah Jane ^a  

^a BRISTOL ROYAL INFIRMARY   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

SMAD PROTEIN; TRANSFORMING GROWTH FACTOR BETA1; WNT PROTEIN;

ARTERY CALCIFICATION; CARDIOVASCULAR DISEASE; CELL DIFFERENTIATION; DIABETES MELLITUS; EDITORIAL; HUMAN; HYPERTENSION; MYOFIBROBLAST; PRIORITY JOURNAL; PROTEIN FUNCTION; REGULATORY MECHANISM;

ANIMALS; CARDIOVASCULAR DISEASES; CELL DIFFERENTIATION; FIBROBLASTS; HUMANS; MODELS, BIOLOGICAL; SIGNAL TRANSDUCTION; SMAD PROTEINS; TRANSFORMING GROWTH FACTOR BETA1; WNT PROTEINS;

EID: 63349107395     PISSN: 00222828     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.yjmcc.2009.02.008     Document Type: Editorial

References (26)

1. Logan C.Y., and Nusse R. The Wnt signaling pathway in development and disease. Annu. Rev. Cell Dev. Biol. 20 1 (2004) 781-810
2. Clevers H. Wnt/β-catenin signaling in development and disease. Cell 127 (2006) 469-480
3. Wang X., Xiao Y., Mou Y., Zhao Y., Blankesteijn M., and Hall J.L. A role for the β-catenin/T-cell factor signaling cascade in vascular remodeling. Circ. Res. 90 (2002) 340-347
4. Uglow E.B., Slater S., Sala-Newby G.B., Aguilera-Garcia C.M., Angelini G.D., Newby A.C., et al. Dismantling of cadherin-mediated cell-cell contacts modulates smooth muscle proliferation. Circ. Res. 92 (2003) 1314-1321
5. Quasnichka H., Slater S.C., Beeching C.A., Boehm M., Sala-Newby G.B., and George S.J. Regulation of smooth muscle cell proliferation by β-catenin/TCF signaling involves modulation of cyclin D1 and p21 expression. Circ. Res. 99 12 (2006) 1329-1337
6. Slater S., Koutsouki E., Jackson C.L., Bush R.C., Angelini G.D., Newby A.C., et al. β-catenin complex and its association with vascular smooth muscle cell proliferation. Arterioscler. Thromb. Vasc. Biol. 24 (2004) 1204-1210
7. Wang X., Xiao Y., Mou Y., Zhao Y., Blankesteijn M., and Hall J.L. β-catenin/T-cell factor signaling cascade in vascular remodelling. Circ. Res. 90 (2002) 340-347
8. Wang X., Adhikari N., Li Q., and Hall J.L. The LDL receptor related protein LRP6 regulates proliferation and survival through the Wnt cascade in vascular smooth muscle cells. Am. J. Physiol, Heart Circ. Physiol. 287 (2004) H2376-H2383
9. Ezan J., Leroux L., Barandon L., Dufourcq P., Jaspard B., Moreau C., et al. FrzA/sFRP-1, a secreted antagonist of the Wnt-Frizzled pathway, controls vascular cell proliferation in vitro and in vivo. Cardiovasc. Res. 63 (2004) 731-738
10. Mao C., Malek T.B.O., Pueyo M.E., Steg P.G., and Soubrier F. frzb-1 and frizzled receptor fz1 and fz2 genes in the rat aorta after balloon injury. Arterioscler. Thromb. Vasc. Biol. 20 (2000) 43-51
11. Kirton J.P., Crofts N.J., George S.J., Brennan K., and Canfield A.E. Wnt/{beta}-Catenin signaling stimulates chondrogenic and inhibits adipogenic differentiation of pericytes. Potential relevance to vascular disease?. Circ. Res. 101 (2007) 581-589
12. Shao J.S., Al Aly Z., Lai C.-F., Cheng S.-L., Cai J., Huang E., et al. Vascular Bmp-Msx2-Wnt signalling and oxidative stress in arterial calcification. Ann. N.Y. Acad. Sci. 1117 (2007) 40-50
13. Al-Aly Z., Shao J.-S., Lai C.-F., Huang E., Cai J., Behrmann A., et al. Aortic Msx2-Wnt calcification cascade is regulated by TNF-{alpha} dependent signals in diabetic Ldlr / mice. Arterioscler. Thromb. Vasc. Biol. 27 12 (2007) 2589-2596
14. Shafer S.L., and Towler D.A. Transcriptional regulation of SM22α by Wnt3a: Convergence with TGFβ1/Smad signaling at a novel regulatory element. J. Mol. Cell. Cardiol. 46 (2009) 621-635
15. Collett G.D.M., and Canfield A.E. Angiogenesis and pericytes in the initiation of ectopic calcification. Circ. Res. 96 9 (2005) 930-938
16. Shi Y., O'Brien J.E., Fard A., Mannion J.D., Wang D., and Zalewski A. Adventitial myofibroblasts contribute to neointimal formation in injured porcine coronary arteries. Circulation 94 7 (1996) 1655-1664
17. Morgan K.G., and Gangopadhyay S.S. Signal transduction in smooth muscle: invited review: cross-bridge regulation by thin filament-associated proteins. J. Appl. Physiol. 91 2 (2001) 953-962
18. Hautmann M.B., Adam P.J., and Owens G.K. Similarities and differences in smooth muscle a-actin induction by TGF-b in smooth muscle versus non-smooth muscle cells. Arterioscler. Thromb. Vasc. Biol. 19 (1999) 2049-2058
19. Yoshida T., and Owens G.K. Molecular determinants of vascular smooth muscle cell diversity. Circ. Res. 96 3 (2005) 280-291
20. Hinz B., Phan S.H., Thannickal V.J., Galli A., Bochaton-Piallat M.-L., and Gabbiani G. The myofibroblast. One function, multiple origins. Am. J. Pathol. 170 6 (2007) 1807-1816
21. Qiu P., Ritchie R.P., Fu Z., Cao D., Cumming J., Miano J.M., et al. Myocardin enhances Smad3-mediated transforming growth factor-{beta}1 signaling in a CArG box-independent manner: Smad-binding element is an important cis element for SM22{alpha} transcription in vivo. Circ. Res. 97 10 (2005) 983-991
22. Al-Aly Z. Arterial calcification: a tumor necrosis factor-alpha mediated vascular Wnt-opathy. Translational Res. 151 5 (2008) 233
23. Crawford H.C., Fingleton B.M., Rudolph-Owen L.A., Heppner Goss K.J., Rubinfeld B., Polakis P., et al. The metalloproteinase matrilysin is a target of β-catenin transactivation in intestinal tumors. Oncogene 18 (1999) 2883-2891
24. Lyu J., and Joo C.-K. Wnt 7a up-regulates matrix metalloproteinase-12 expression and promotes cell proliferation in corneal epithelial cells during wound healing. J. Biol. Chem. 280 22 (2005) 21653-21660
25. Takahashi M., Tsunoda T., Seiki M., Nakamura Y., and Furukawa Y. Identification of membrane-type matrix metalloproteinase-1 as a target of the b-catenin/Tcf4 complex in human colorectal cancers. Oncogene 21 (2002) 5861-5867
26. Marchenko N.D., Marchenko G.N., Weinreb R.N., Lindsey J.D., Kyshtoobayeva A., Crawford H.C., et al. [beta]-Catenin regulates the gene of MMP-26, a novel matrix metalloproteinase expressed both in carcinomas and normal epithelial cells. Int. J. Biochem. Cell Biol. 36 5 (2004) 942