-
1
-
-
0035191389
-
Colchicine and griseofulvin inhibit VCAM-1 expression on human vascular endothelial cells-evidence for the association of VCAM-1 expression with microtubules
-
Asahina A, Tada Y et al (2001) Colchicine and griseofulvin inhibit VCAM-1 expression on human vascular endothelial cells-evidence for the association of VCAM-1 expression with microtubules. J Dermatol Sci 25(1):1-9.
-
(2001)
J Dermatol Sci
, vol.25
, Issue.1
, pp. 1-9
-
-
Asahina, A.1
Tada, Y.2
-
2
-
-
33750486215
-
Multidrug resistance in locally advanced breast cancer
-
Atalay C, Deliloglu Gurhan I et al (2006) Multidrug resistance in locally advanced breast cancer. Tumour Biol 27(6):309-318.
-
(2006)
Tumour Biol
, vol.27
, Issue.6
, pp. 309-318
-
-
Atalay, C.1
Deliloglu Gurhan, I.2
-
3
-
-
77958507144
-
Temporal aspects of the action of ASA404 (vadimezan; DMXAA)
-
Baguley BC, Siemann DW (2010) Temporal aspects of the action of ASA404 (vadimezan; DMXAA). Expert Opin Investig Drugs 19(11):1413-1425.
-
(2010)
Expert Opin Investig Drugs
, vol.19
, Issue.11
, pp. 1413-1425
-
-
Baguley, B.C.1
Siemann, D.W.2
-
4
-
-
0025793698
-
Inhibition of growth of colon 38 adenocarcinoma by vinblastine and colchicine: Evidence for a vascular mechanism
-
Baguley BC, Holdaway KM et al (1991) Inhibition of growth of colon 38 adenocarcinoma by vinblastine and colchicine: evidence for a vascular mechanism. Eur J Cancer 27(4):482-487.
-
(1991)
Eur J Cancer
, vol.27
, Issue.4
, pp. 482-487
-
-
Baguley, B.C.1
Holdaway, K.M.2
-
5
-
-
0025183762
-
Binding of dolastatin 10 to tubulin at a distinct site for peptide antimitotic agents near the exchangeable nucleotide and vinca alkaloid sites
-
Bai RL, Pettit GR et al (1990) Binding of dolastatin 10 to tubulin at a distinct site for peptide antimitotic agents near the exchangeable nucleotide and vinca alkaloid sites. J Biol Chem 265(28):17141-17149.
-
(1990)
J Biol Chem
, vol.265
, Issue.28
, pp. 17141-17149
-
-
Bai, R.L.1
Pettit, G.R.2
-
6
-
-
42249104716
-
Efficacy of selected natural products as therapeutic agents against cancer
-
Banerjee S, Wang Z et al (2008) Efficacy of selected natural products as therapeutic agents against cancer. J Nat Prod 71(3):492-496.
-
(2008)
J Nat Prod
, vol.71
, Issue.3
, pp. 492-496
-
-
Banerjee, S.1
Wang, Z.2
-
7
-
-
75149128685
-
Phase III trial of vinflunine plus best supportive care compared with best supportive care alone after a platinum-containing regimen in patients with advanced transitional cell carcinoma of the urothelial tract
-
Bellmunt J, Theodore C et al (2009) Phase III trial of vinflunine plus best supportive care compared with best supportive care alone after a platinum-containing regimen in patients with advanced transitional cell carcinoma of the urothelial tract. J Clin Oncol 27(27):4454-4461.
-
(2009)
J Clin Oncol
, vol.27
, Issue.27
, pp. 4454-4461
-
-
Bellmunt, J.1
Theodore, C.2
-
8
-
-
47949099628
-
Modes of resistance to anti-angiogenic therapy
-
Bergers G, Hanahan D (2008) Modes of resistance to anti-angiogenic therapy. Nat Rev Cancer 8(8):592-603.
-
(2008)
Nat Rev Cancer
, vol.8
, Issue.8
, pp. 592-603
-
-
Bergers, G.1
Hanahan, D.2
-
9
-
-
0027459147
-
Flavone acetic acid-from laboratory to clinic and back
-
Bibby MC, Double JA (1993) Flavone acetic acid-from laboratory to clinic and back. Anticancer Drugs 4(1):3-17.
-
(1993)
Anticancer Drugs
, vol.4
, Issue.1
, pp. 3-17
-
-
Bibby, M.C.1
Double, J.A.2
-
10
-
-
0023129401
-
Factors involved in the anti-cancer activity of the investigational agents LM985 (flavone acetic acid ester) and LM975 (flavone acetic acid)
-
Bibby MC, Double JA et al (1987) Factors involved in the anti-cancer activity of the investigational agents LM985 (flavone acetic acid ester) and LM975 (flavone acetic acid). Br J Cancer 55(2):159-163.
-
(1987)
Br J Cancer
, vol.55
, Issue.2
, pp. 159-163
-
-
Bibby, M.C.1
Double, J.A.2
-
11
-
-
0024555010
-
Reduction of tumor blood flow by flavone acetic acid: A possible component of therapy
-
Bibby MC, Double JA et al (1989) Reduction of tumor blood flow by flavone acetic acid: a possible component of therapy. J Natl Cancer Inst 81(3):216-220.
-
(1989)
J Natl Cancer Inst
, vol.81
, Issue.3
, pp. 216-220
-
-
Bibby, M.C.1
Double, J.A.2
-
12
-
-
0043031136
-
The vascular targeting agent combretastatin A-4-phosphate induces neutrophil recruitment to endothelial cells in vitro
-
Brooks AC, Kanthou C et al (2003) The vascular targeting agent combretastatin A-4-phosphate induces neutrophil recruitment to endothelial cells in vitro. Anticancer Res 23(4):3199-3206.
-
(2003)
Anticancer Res
, vol.23
, Issue.4
, pp. 3199-3206
-
-
Brooks, A.C.1
Kanthou, C.2
-
13
-
-
79956328903
-
Molecular mechanisms and clinical applications of angiogenesis
-
Carmeliet P, Jain RK (2011a) Molecular mechanisms and clinical applications of angiogenesis. Nature 473(7347):298-307.
-
(2011)
Nature
, vol.473
, Issue.7347
, pp. 298-307
-
-
Carmeliet, P.1
Jain, R.K.2
-
14
-
-
79957894276
-
Principles and mechanisms of vessel normalization for cancer and other angiogenic diseases
-
Carmeliet P, Jain RK (2011b) Principles and mechanisms of vessel normalization for cancer and other angiogenic diseases. Nat Rev Drug Discov 10(6):417-427.
-
(2011)
Nat Rev Drug Discov
, vol.10
, Issue.6
, pp. 417-427
-
-
Carmeliet, P.1
Jain, R.K.2
-
15
-
-
0027394450
-
Tumour necrosis factor-alpha plasma levels after flavone acetic acid administration in man and mouse
-
Chabot GG, Branellec D et al (1993) Tumour necrosis factor-alpha plasma levels after flavone acetic acid administration in man and mouse. Eur J Cancer 29A(5):729-733.
-
(1993)
Eur J Cancer
, vol.29 A
, Issue.5
, pp. 729-733
-
-
Chabot, G.G.1
Branellec, D.2
-
16
-
-
34547810999
-
Effect of vascular targeting agent Oxi4503 on tumor cell kinetics in a mouse model of colorectal liver metastasis
-
Chan LS, Malcontenti-Wilson C et al (2007) Effect of vascular targeting agent Oxi4503 on tumor cell kinetics in a mouse model of colorectal liver metastasis. Anticancer Res 27(4B): 2317-2323.
-
(2007)
Anticancer Res
, vol.27
, Issue.4 B
, pp. 2317-2323
-
-
Chan, L.S.1
Malcontenti-wilson, C.2
-
17
-
-
0032950870
-
Anti-vascular approaches to solid tumour therapy: Evaluation of combretastatin A4 phosphate
-
Chaplin DJ, Pettit GR et al (1999) Anti-vascular approaches to solid tumour therapy: evaluation of combretastatin A4 phosphate. Anticancer Res 19(1A):189-195.
-
(1999)
Anticancer Res
, vol.19
, Issue.1 A
, pp. 189-195
-
-
Chaplin, D.J.1
Pettit, G.R.2
-
18
-
-
0033565644
-
Induction of intratumoral tumor necrosis factor (TNF) synthesis and hemorrhagic necrosis by 5,6-dimethylxanthenone-4-acetic acid (DMXAA) in TNF knockout mice
-
Ching LM, Goldsmith D et al (1999) Induction of intratumoral tumor necrosis factor (TNF) synthesis and hemorrhagic necrosis by 5,6-dimethylxanthenone-4-acetic acid (DMXAA) in TNF knockout mice. Cancer Res 59(14):3304-3307.
-
(1999)
Cancer Res
, vol.59
, Issue.14
, pp. 3304-3307
-
-
Ching, L.M.1
Goldsmith, D.2
-
19
-
-
0037125028
-
Induction of endothelial cell apoptosis by the antivascular agent 5,6-dimethylxanthenone-4-acetic acid
-
Ching LM, Cao Z et al (2002) Induction of endothelial cell apoptosis by the antivascular agent 5,6-dimethylxanthenone-4-acetic acid. Br J Cancer 86(12):1937-1942.
-
(2002)
Br J Cancer
, vol.86
, Issue.12
, pp. 1937-1942
-
-
Ching, L.M.1
Cao, Z.2
-
20
-
-
1642352048
-
Relationship between tumour endothelial cell apoptosis and tumour blood flow shutdown following treatment with the antivascular agent DMXAA in mice
-
Ching LM, Zwain S et al (2004) Relationship between tumour endothelial cell apoptosis and tumour blood flow shutdown following treatment with the antivascular agent DMXAA in mice. Br J Cancer 90(4):906-910.
-
(2004)
Br J Cancer
, vol.90
, Issue.4
, pp. 906-910
-
-
Ching, L.M.1
Zwain, S.2
-
21
-
-
37249045539
-
Consequences of increased vascular permeability induced by treatment of mice with 5,6-dimethylxanthenone-4-acetic acid (DMXAA) and thalidomide
-
Chung F, Liu J et al (2008) Consequences of increased vascular permeability induced by treatment of mice with 5,6-dimethylxanthenone-4-acetic acid (DMXAA) and thalidomide. Cancer Chemother Pharmacol 61(3):497-502.
-
(2008)
Cancer Chemother Pharmacol
, vol.61
, Issue.3
, pp. 497-502
-
-
Chung, F.1
Liu, J.2
-
22
-
-
0035282925
-
A permissive role for tumor necrosis factor in vascular endothelial growth factor-induced vascular permeability
-
Clauss M, Sunderkotter C et al (2001) A permissive role for tumor necrosis factor in vascular endothelial growth factor-induced vascular permeability. Blood 97(5):1321-1329.
-
(2001)
Blood
, vol.97
, Issue.5
, pp. 1321-1329
-
-
Clauss, M.1
Sunderkotter, C.2
-
23
-
-
0029144844
-
Colchicine alters the quantitative and qualitative display of selectins on endothelial cells and neutrophils
-
Cronstein BN, Molad Y et al (1995) Colchicine alters the quantitative and qualitative display of selectins on endothelial cells and neutrophils. J Clin Invest 96(2):994-1002.
-
(1995)
J Clin Invest
, vol.96
, Issue.2
, pp. 994-1002
-
-
Cronstein, B.N.1
Molad, Y.2
-
24
-
-
33646844469
-
A phase II study of vinflunine in bladder cancer patients progressing after first-line platinum-containing regimen
-
Culine S, Theodore C et al (2006) A phase II study of vinflunine in bladder cancer patients progressing after first-line platinum-containing regimen. Br J Cancer 94(10):1395-1401.
-
(2006)
Br J Cancer
, vol.94
, Issue.10
, pp. 1395-1401
-
-
Culine, S.1
Theodore, C.2
-
25
-
-
0028331925
-
2-Methoxyestradiol, an endogenous mammalian metabolite, inhibits tubulin polymerization by interacting at the colchicine site
-
D'Amato RJ, Lin CM et al (1994) 2-Methoxyestradiol, an endogenous mammalian metabolite, inhibits tubulin polymerization by interacting at the colchicine site. Proc Natl Acad Sci U S A 91(9):3964-3968.
-
(1994)
Proc Natl Acad Sci U S A
, vol.91
, Issue.9
, pp. 3964-3968
-
-
D'Amato, R.J.1
Lin, C.M.2
-
26
-
-
0030951899
-
Combretastatin A-4, an agent that displays potent and selective toxicity toward tumor vasculature
-
Dark GG, Hill SA et al (1997) Combretastatin A-4, an agent that displays potent and selective toxicity toward tumor vasculature. Cancer Res 57(10):1829-1834.
-
(1997)
Cancer Res
, vol.57
, Issue.10
, pp. 1829-1834
-
-
Dark, G.G.1
Hill, S.A.2
-
27
-
-
0032918412
-
Blood vessel maturation: Vascular development comes of age
-
Darland DC, D'Amore PA (1999) Blood vessel maturation: vascular development comes of age. J Clin Invest 103(2):157-158.
-
(1999)
J Clin Invest
, vol.103
, Issue.2
, pp. 157-158
-
-
Darland, D.C.1
D'Amore, P.A.2
-
28
-
-
0020081554
-
Endothelial cell proliferation as a novel approach to targeting tumour therapy
-
Denekamp J (1982) Endothelial cell proliferation as a novel approach to targeting tumour therapy. Br J Cancer 45(1):136-139.
-
(1982)
Br J Cancer
, vol.45
, Issue.1
, pp. 136-139
-
-
Denekamp, J.1
-
29
-
-
0020449692
-
Endothelial-cell proliferation in experimental tumours
-
Denekamp J, Hobson B (1982) Endothelial-cell proliferation in experimental tumours. Br J Cancer 46(5):711-720.
-
(1982)
Br J Cancer
, vol.46
, Issue.5
, pp. 711-720
-
-
Denekamp, J.1
Hobson, B.2
-
30
-
-
0023026999
-
Pharmacokinetics and anti-tumour activity of LM985 in mice bearing transplantable adenocarcinomas of the colon
-
Double JA, Bibby MC et al (1986) Pharmacokinetics and anti-tumour activity of LM985 in mice bearing transplantable adenocarcinomas of the colon. Br J Cancer 54(4):595-600.
-
(1986)
Br J Cancer
, vol.54
, Issue.4
, pp. 595-600
-
-
Double, J.A.1
Bibby, M.C.2
-
31
-
-
34047175559
-
Targeting VEGF-A to treat cancer and age-related macular degeneration
-
Ferrara N, Mass RD et al (2007) Targeting VEGF-A to treat cancer and age-related macular degeneration. Annu Rev Med 58:491-504.
-
(2007)
Annu Rev Med
, vol.58
, pp. 491-504
-
-
Ferrara, N.1
Mass, R.D.2
-
32
-
-
77954220989
-
Colchicine poisoning: The dark side of an ancient drug
-
Finkelstein Y, Aks SE et al (2010) Colchicine poisoning: the dark side of an ancient drug. Clin Toxicol (Phila) 48(5):407-414.
-
(2010)
Clin Toxicol (Phila)
, vol.48
, Issue.5
, pp. 407-414
-
-
Finkelstein, Y.1
Aks, S.E.2
-
33
-
-
0021978223
-
Tumor angiogenesis
-
Folkman J (1985) Tumor angiogenesis. Adv Cancer Res 43:175-203.
-
(1985)
Adv Cancer Res
, vol.43
, pp. 175-203
-
-
Folkman, J.1
-
34
-
-
0035064594
-
Effects of combretastatin A4 phosphate on endothelial cell morphology in vitro and relationship to tumour vascular targeting activity in vivo
-
Galbraith SM, Chaplin DJ et al (2001) Effects of combretastatin A4 phosphate on endothelial cell morphology in vitro and relationship to tumour vascular targeting activity in vivo. Anticancer Res 21(1A):93-102.
-
(2001)
Anticancer Res
, vol.21
, Issue.1 A
, pp. 93-102
-
-
Galbraith, S.M.1
Chaplin, D.J.2
-
35
-
-
33747894345
-
A phase I study of intravenous TZT-1027 administered on day 1 and day 8 of a three-weekly cycle in combination with carboplatin given on day 1 alone in patients with advanced solid tumours
-
Greystoke A, Blagden S et al (2006) A phase I study of intravenous TZT-1027 administered on day 1 and day 8 of a three-weekly cycle in combination with carboplatin given on day 1 alone in patients with advanced solid tumours. Ann Oncol 17(8):1313-1319.
-
(2006)
Ann Oncol
, vol.17
, Issue.8
, pp. 1313-1319
-
-
Greystoke, A.1
Blagden, S.2
-
36
-
-
0032758736
-
In vivo and in vitro evaluation of combretastatin A-4 and its sodium phosphate prodrug
-
Grosios K, Holwell SE et al (1999) In vivo and in vitro evaluation of combretastatin A-4 and its sodium phosphate prodrug. Br J Cancer 81(8):1318-1327.
-
(1999)
Br J Cancer
, vol.81
, Issue.8
, pp. 1318-1327
-
-
Grosios, K.1
Holwell, S.E.2
-
37
-
-
0031587936
-
Flavone acetic acid stimulates nitric oxide and peroxynitrite production in subcutaneous mouse tumors
-
Harris SR, Thorgeirsson UP (1997) Flavone acetic acid stimulates nitric oxide and peroxynitrite production in subcutaneous mouse tumors. Biochem Biophys Res Commun 235(3):509-514.
-
(1997)
Biochem Biophys Res Commun
, vol.235
, Issue.3
, pp. 509-514
-
-
Harris, S.R.1
Thorgeirsson, U.P.2
-
38
-
-
0026426158
-
Phase I clinical and pharmacokinetic trial of flavone acetic acid
-
Havlin KA, Kuhn JG et al (1991) Phase I clinical and pharmacokinetic trial of flavone acetic acid. J Natl Cancer Inst 83(2):124-128.
-
(1991)
J Natl Cancer Inst
, vol.83
, Issue.2
, pp. 124-128
-
-
Havlin, K.A.1
Kuhn, J.G.2
-
39
-
-
0033105721
-
Superior in vivo experimental antitumour activity of vinflunine, relative to vinorelbine, in a panel of human tumour xenografts
-
Hill BT, Fiebig HH et al (1999) Superior in vivo experimental antitumour activity of vinflunine, relative to vinorelbine, in a panel of human tumour xenografts. Eur J Cancer 35(3):512-520.
-
(1999)
Eur J Cancer
, vol.35
, Issue.3
, pp. 512-520
-
-
Hill, B.T.1
Fiebig, H.H.2
-
40
-
-
0035150786
-
Anti-vascular effects of vinflunine in the MAC 15A transplantable adenocarcinoma model
-
Holwell SE, Hill BT et al (2001) Anti-vascular effects of vinflunine in the MAC 15A transplantable adenocarcinoma model. Br J Cancer 84(2):290-295.
-
(2001)
Br J Cancer
, vol.84
, Issue.2
, pp. 290-295
-
-
Holwell, S.E.1
Hill, B.T.2
-
41
-
-
51049105074
-
Antiangiogenic vinflunine affects EB1 localization and microtubule targeting to adhesion sites
-
Honore S, Pagano A et al (2008) Antiangiogenic vinflunine affects EB1 localization and microtubule targeting to adhesion sites. Mol Cancer Ther 7(7):2080-2089.
-
(2008)
Mol Cancer Ther
, vol.7
, Issue.7
, pp. 2080-2089
-
-
Honore, S.1
Pagano, A.2
-
42
-
-
33748869678
-
Pathophysiologic effects of vascular-targeting agents and the implications for combination with conventional therapies
-
Horsman MR, Siemann DW (2006) Pathophysiologic effects of vascular-targeting agents and the implications for combination with conventional therapies. Cancer Res 66(24):11520-11539.
-
(2006)
Cancer Res
, vol.66
, Issue.24
, pp. 11520-11539
-
-
Horsman, M.R.1
Siemann, D.W.2
-
43
-
-
0034472914
-
Combretastatins novel vascular targeting drugs for improving anti-cancer therapy. Combretastatins and conventional therapy
-
Horsman MR, Murata R et al (2000) Combretastatins novel vascular targeting drugs for improving anti-cancer therapy. Combretastatins and conventional therapy. Adv Exp Med Biol 476:311-323.
-
(2000)
Adv Exp Med Biol
, vol.476
, pp. 311-323
-
-
Horsman, M.R.1
Murata, R.2
-
44
-
-
42149130973
-
Phase I study of TZT-1027, a novel synthetic dolastatin 10 derivative, for the treatment of patients with non-small cell lung cancer
-
Horti J, Juhasz E et al (2008) Phase I study of TZT-1027, a novel synthetic dolastatin 10 derivative, for the treatment of patients with non-small cell lung cancer. Cancer Chemother Pharmacol 62(1):173-180.
-
(2008)
Cancer Chemother Pharmacol
, vol.62
, Issue.1
, pp. 173-180
-
-
Horti, J.1
Juhasz, E.2
-
45
-
-
0038376002
-
Molecular regulation of vessel maturation
-
Jain RK (2003) Molecular regulation of vessel maturation. Nat Med 9(6):685-693.
-
(2003)
Nat Med
, vol.9
, Issue.6
, pp. 685-693
-
-
Jain, R.K.1
-
46
-
-
11844254414
-
Normalization of tumor vasculature: An emerging concept in antiangiogenic therapy
-
Jain RK (2005) Normalization of tumor vasculature: an emerging concept in antiangiogenic therapy. Science 307(5706):58-62.
-
(2005)
Science
, vol.307
, Issue.5706
, pp. 58-62
-
-
Jain, R.K.1
-
47
-
-
30944446883
-
Lessons from phase III clinical trials on anti-VEGF therapy for cancer
-
Jain RK, Duda DG et al (2006) Lessons from phase III clinical trials on anti-VEGF therapy for cancer. Nat Clin Pract Oncol 3(1):24-40.
-
(2006)
Nat Clin Pract Oncol
, vol.3
, Issue.1
, pp. 24-40
-
-
Jain, R.K.1
Duda, D.G.2
-
48
-
-
0033083206
-
Stimulation of tumors to synthesize tumor necrosis factor-alpha in situ using 5,6-dimethylxanthenone-4-acetic acid: A novel approach to cancer therapy
-
Joseph WR, Cao Z et al (1999) Stimulation of tumors to synthesize tumor necrosis factor-alpha in situ using 5,6-dimethylxanthenone-4-acetic acid: a novel approach to cancer therapy. Cancer Res 59(3):633-638.
-
(1999)
Cancer Res
, vol.59
, Issue.3
, pp. 633-638
-
-
Joseph, W.R.1
Cao, Z.2
-
49
-
-
0037085753
-
The tumor vascular targeting agent combretastatin A-4-phosphate induces reorganization of the actin cytoskeleton and early membrane blebbing in human endothelial cells
-
Kanthou C, Tozer GM (2002) The tumor vascular targeting agent combretastatin A-4-phosphate induces reorganization of the actin cytoskeleton and early membrane blebbing in human endothelial cells. Blood 99(6):2060-2069.
-
(2002)
Blood
, vol.99
, Issue.6
, pp. 2060-2069
-
-
Kanthou, C.1
Tozer, G.M.2
-
50
-
-
35148825036
-
Antitumor and antivascular effects of AVE8062 in ovarian carcinoma
-
Kim TJ, Ravoori M et al (2007) Antitumor and antivascular effects of AVE8062 in ovarian carcinoma. Cancer Res 67(19):9337-9345.
-
(2007)
Cancer Res
, vol.67
, Issue.19
, pp. 9337-9345
-
-
Kim, T.J.1
Ravoori, M.2
-
51
-
-
0030612225
-
Antitumor activity of TZT-1027, a novel dolastatin 10 derivative
-
Kobayashi M, Natsume T et al (1997) Antitumor activity of TZT-1027, a novel dolastatin 10 derivative. Jpn J Cancer Res 88(3):316-327.
-
(1997)
Jpn J Cancer Res
, vol.88
, Issue.3
, pp. 316-327
-
-
Kobayashi, M.1
Natsume, T.2
-
52
-
-
0034773326
-
Vinflunine, the latest Vinca alkaloid in clinical development. A review of its preclinical anticancer properties
-
Kruczynski A, Hill BT (2001) Vinflunine, the latest Vinca alkaloid in clinical development. A review of its preclinical anticancer properties. Crit Rev Oncol Hematol 40(2):159-173.
-
(2001)
Crit Rev Oncol Hematol
, vol.40
, Issue.2
, pp. 159-173
-
-
Kruczynski, A.1
Hill, B.T.2
-
53
-
-
0032031453
-
Antimitotic and tubulin-interacting properties of vinflunine, a novel fluorinated Vinca alkaloid
-
Kruczynski A, Barret JM et al (1998) Antimitotic and tubulin-interacting properties of vinflunine, a novel fluorinated Vinca alkaloid. Biochem Pharmacol 55(5):635-648.
-
(1998)
Biochem Pharmacol
, vol.55
, Issue.5
, pp. 635-648
-
-
Kruczynski, A.1
Barret, J.M.2
-
54
-
-
33750075041
-
Anti-angiogenic, vascular-disrupting and anti-metastatic activities of vinflunine, the latest vinca alkaloid in clinical development
-
Kruczynski A, Poli M et al (2006) Anti-angiogenic, vascular-disrupting and anti-metastatic activities of vinflunine, the latest vinca alkaloid in clinical development. Eur J Cancer 42(16):2821-2832.
-
(2006)
Eur J Cancer
, vol.42
, Issue.16
, pp. 2821-2832
-
-
Kruczynski, A.1
Poli, M.2
-
55
-
-
34047271956
-
Combretastatin A-4-phosphate effectively increases tumor retention of the therapeutic antibody, 131I-A5B7, even at doses that are sub-optimal for vascular shut-down
-
Lankester KJ, Maxwell RJ et al (2007) Combretastatin A-4-phosphate effectively increases tumor retention of the therapeutic antibody, 131I-A5B7, even at doses that are sub-optimal for vascular shut-down. Int J Oncol 30(2):453-460.
-
(2007)
Int J Oncol
, vol.30
, Issue.2
, pp. 453-460
-
-
Lankester, K.J.1
Maxwell, R.J.2
-
56
-
-
80051638135
-
Randomized phase III placebo-controlled trial of carboplatin and paclitaxel with or without the vascular disrupting agent vadimezan (ASA404) in advanced non-small-cell lung cancer
-
Lara PN Jr, Douillard JY et al (2011) Randomized phase III placebo-controlled trial of carboplatin and paclitaxel with or without the vascular disrupting agent vadimezan (ASA404) in advanced non-small-cell lung cancer. J Clin Oncol 29(22):2965-2971.
-
(2011)
J Clin Oncol
, vol.29
, Issue.22
, pp. 2965-2971
-
-
Lara, P.N.1
Douillard, J.Y.2
-
57
-
-
0031858141
-
Enhancement of the anti-tumour effects of the antivascular agent 5,6-dimethylxanthenone-4-acetic acid (DMXAA) by combination with 5-hydroxytryptamine and bioreductive drugs
-
Lash CJ, Li AE et al (1998) Enhancement of the anti-tumour effects of the antivascular agent 5,6-dimethylxanthenone-4-acetic acid (DMXAA) by combination with 5-hydroxytryptamine and bioreductive drugs. Br J Cancer 78(4):439-445.
-
(1998)
Br J Cancer
, vol.78
, Issue.4
, pp. 439-445
-
-
Lash, C.J.1
Li, A.E.2
-
58
-
-
0031742231
-
Targeting the tumor vasculature with combretastatin A-4 disodium phosphate: Effects on radiation therapy
-
Li L, Rojiani A et al (1998) Targeting the tumor vasculature with combretastatin A-4 disodium phosphate: effects on radiation therapy. Int J Radiat Oncol Biol Phys 42(4):899-903.
-
(1998)
Int J Radiat Oncol Biol Phys
, vol.42
, Issue.4
, pp. 899-903
-
-
Li, L.1
Rojiani, A.2
-
59
-
-
0023801309
-
Interactions of tubulin with potent natural and synthetic analogs of the antimitotic agent combretastatin: A structure-activity study
-
Lin CM, Singh SB et al (1988) Interactions of tubulin with potent natural and synthetic analogs of the antimitotic agent combretastatin: a structure-activity study. Mol Pharmacol 34(2):200-208.
-
(1988)
Mol Pharmacol
, vol.34
, Issue.2
, pp. 200-208
-
-
Lin, C.M.1
Singh, S.B.2
-
60
-
-
40549125995
-
Phase I clinical evaluation of ZD6126, a novel vasculartargeting agent, in patients with solid tumors
-
LoRusso PM, Gadgeel SM et al (2008) Phase I clinical evaluation of ZD6126, a novel vasculartargeting agent, in patients with solid tumors. Invest New Drugs 26(2):159-167.
-
(2008)
Invest New Drugs
, vol.26
, Issue.2
, pp. 159-167
-
-
LoRusso, P.M.1
Gadgeel, S.M.2
-
61
-
-
0002410998
-
Factors determining the action of colchicine on tumour growth
-
Ludford RJ (1948) Factors determining the action of colchicine on tumour growth. Br J Cancer 2(1):75-86.
-
(1948)
Br J Cancer
, vol.2
, Issue.1
, pp. 75-86
-
-
Ludford, R.J.1
-
62
-
-
10744231706
-
2ME2 inhibits tumor growth and angiogenesis by disrupting microtubules and dysregulating HIF
-
Mabjeesh NJ, Escuin D et al (2003) 2ME2 inhibits tumor growth and angiogenesis by disrupting microtubules and dysregulating HIF. Cancer Cell 3(4):363-375.
-
(2003)
Cancer Cell
, vol.3
, Issue.4
, pp. 363-375
-
-
Mabjeesh, N.J.1
Escuin, D.2
-
63
-
-
77956324472
-
Leukemia regression by vascular disruption and antiangiogenic therapy
-
Madlambayan GJ, Meacham AM et al (2010) Leukemia regression by vascular disruption and antiangiogenic therapy. Blood 116(9):1539-1547.
-
(2010)
Blood
, vol.116
, Issue.9
, pp. 1539-1547
-
-
Madlambayan, G.J.1
Meacham, A.M.2
-
64
-
-
57449103348
-
Randomised phase II study of ASA404 combined with carboplatin and paclitaxel in previously untreated advanced non-small cell lung cancer
-
McKeage MJ, Von Pawel J et al (2008) Randomised phase II study of ASA404 combined with carboplatin and paclitaxel in previously untreated advanced non-small cell lung cancer. Br J Cancer 99(12):2006-2012.
-
(2008)
Br J Cancer
, vol.99
, Issue.12
, pp. 2006-2012
-
-
McKeage, M.J.1
Von Pawel, J.2
-
65
-
-
67449123059
-
Phase II study of ASA404 (vadimezan, 5,6-dimethylxanthenone-4-acetic acid/DMXAA) 1800 mg/m(2) combined with carboplatin and paclitaxel in previously untreated advanced non-small cell lung cancer
-
McKeage MJ, Reck M et al (2009) Phase II study of ASA404 (vadimezan, 5,6-dimethylxanthenone-4-acetic acid/DMXAA) 1800 mg/m(2) combined with carboplatin and paclitaxel in previously untreated advanced non-small cell lung cancer. Lung Cancer 65(2):192-197.
-
(2009)
Lung Cancer
, vol.65
, Issue.2
, pp. 192-197
-
-
McKeage, M.J.1
Reck, M.2
-
66
-
-
0037382380
-
Vascular-targeting activity of ZD6126, a novel tubulin-binding agent
-
Micheletti G, Poli M et al (2003) Vascular-targeting activity of ZD6126, a novel tubulin-binding agent. Cancer Res 63(7):1534-1537.
-
(2003)
Cancer Res
, vol.63
, Issue.7
, pp. 1534-1537
-
-
Micheletti, G.1
Poli, M.2
-
67
-
-
77955877747
-
Primary endothelial damage is the mechanism of cardiotoxicity of tubulin-binding drugs
-
Mikaelian I, Buness A et al (2010) Primary endothelial damage is the mechanism of cardiotoxicity of tubulin-binding drugs. Toxicol Sci 117(1):144-151.
-
(2010)
Toxicol Sci
, vol.117
, Issue.1
, pp. 144-151
-
-
Mikaelian, I.1
Buness, A.2
-
68
-
-
0033853789
-
Characterization of the interaction of TZT-1027, a potent antitumor agent, with tubulin
-
Natsume T, Watanabe J et al (2000) Characterization of the interaction of TZT-1027, a potent antitumor agent, with tubulin. Jpn J Cancer Res 91(7):737-747.
-
(2000)
Jpn J Cancer Res
, vol.91
, Issue.7
, pp. 737-747
-
-
Natsume, T.1
Watanabe, J.2
-
69
-
-
0141892724
-
Antitumor activity of TZT-1027 (Soblidotin) against vascular endothelial growth factor-secreting human lung cancer in vivo
-
Natsume T, Watanabe J et al (2003) Antitumor activity of TZT-1027 (Soblidotin) against vascular endothelial growth factor-secreting human lung cancer in vivo. Cancer Sci 94(9):826-833.
-
(2003)
Cancer Sci
, vol.94
, Issue.9
, pp. 826-833
-
-
Natsume, T.1
Watanabe, J.2
-
70
-
-
20344367537
-
Tumour vascular targeting
-
Neri D, Bicknell R (2005) Tumour vascular targeting. Nat Rev Cancer 5(6):436-446.
-
(2005)
Nat Rev Cancer
, vol.5
, Issue.6
, pp. 436-446
-
-
Neri, D.1
Bicknell, R.2
-
71
-
-
0034665163
-
Novel actions of the antitumor drugs vinflunine and vinorelbine on microtubules
-
Ngan VK, Bellman K et al (2000) Novel actions of the antitumor drugs vinflunine and vinorelbine on microtubules. Cancer Res 60(18):5045-5051.
-
(2000)
Cancer Res
, vol.60
, Issue.18
, pp. 5045-5051
-
-
Ngan, V.K.1
Bellman, K.2
-
72
-
-
0033857963
-
TZT-1027, an antimicrotubule agent, attacks tumor vasculature and induces tumor cell death
-
Otani M, Natsume T et al (2000) TZT-1027, an antimicrotubule agent, attacks tumor vasculature and induces tumor cell death. Jpn J Cancer Res 91(8):837-844.
-
(2000)
Jpn J Cancer Res
, vol.91
, Issue.8
, pp. 837-844
-
-
Otani, M.1
Natsume, T.2
-
73
-
-
0033817283
-
Determinants of anti-vascular action by combretastatin A-4 phosphate: Role of nitric oxide
-
Parkins CS, Holder AL et al (2000) Determinants of anti-vascular action by combretastatin A-4 phosphate: role of nitric oxide. Br J Cancer 83(6):811-816.
-
(2000)
Br J Cancer
, vol.83
, Issue.6
, pp. 811-816
-
-
Parkins, C.S.1
Holder, A.L.2
-
74
-
-
33845582571
-
Phase II study of intravenous TZT-1027 in patients with advanced or metastatic soft-tissue sarcomas with prior exposure to anthracycline-based chemotherapy
-
Patel S, Keohan ML et al (2006) Phase II study of intravenous TZT-1027 in patients with advanced or metastatic soft-tissue sarcomas with prior exposure to anthracycline-based chemotherapy. Cancer 107(12):2881-2887.
-
(2006)
Cancer
, vol.107
, Issue.12
, pp. 2881-2887
-
-
Patel, S.1
Keohan, M.L.2
-
75
-
-
0023217561
-
Antineoplastic agents, 122. Constituents of Combretum caffrum
-
Pettit GR, Cragg GM et al (1987) Antineoplastic agents, 122. Constituents of Combretum caffrum. J Nat Prod 50(3):386-391.
-
(1987)
J Nat Prod
, vol.50
, Issue.3
, pp. 386-391
-
-
Pettit, G.R.1
Cragg, G.M.2
-
76
-
-
0024513175
-
Isolation and structure of the strong cell growth and tubulin inhibitor combretastatin A-4
-
Pettit GR, Singh SB et al (1989) Isolation and structure of the strong cell growth and tubulin inhibitor combretastatin A-4. Experientia 45(2):209-211.
-
(1989)
Experientia
, vol.45
, Issue.2
, pp. 209-211
-
-
Pettit, G.R.1
Singh, S.B.2
-
77
-
-
77952399799
-
Phase II study on the addition of ASA404 (vadimezan; 5,6-dimethylxanthenone-4-acetic acid) to docetaxel in CRMPC
-
Pili R, Rosenthal MA et al (2010) Phase II study on the addition of ASA404 (vadimezan; 5,6-dimethylxanthenone-4-acetic acid) to docetaxel in CRMPC. Clin Cancer Res 16(10): 2906-2914.
-
(2010)
Clin Cancer Res
, vol.16
, Issue.10
, pp. 2906-2914
-
-
Pili, R.1
Rosenthal, M.A.2
-
78
-
-
0022589148
-
Flavone acetic acid: A novel agent with preclinical antitumor activity against colon adenocarcinoma 38 in mice
-
Plowman J, Narayanan VL et al (1986) Flavone acetic acid: a novel agent with preclinical antitumor activity against colon adenocarcinoma 38 in mice. Cancer Treat Rep 70(5):631-635.
-
(1986)
Cancer Treat Rep
, vol.70
, Issue.5
, pp. 631-635
-
-
Plowman, J.1
Narayanan, V.L.2
-
79
-
-
0030932849
-
Tumor-associated angiogenesis: Mechanisms, clinical implications, and therapeutic strategies
-
Pluda JM (1997) Tumor-associated angiogenesis: mechanisms, clinical implications, and therapeutic strategies. Semin Oncol 24(2):203-218.
-
(1997)
Semin Oncol
, vol.24
, Issue.2
, pp. 203-218
-
-
Pluda, J.M.1
-
80
-
-
33645533966
-
Antiangiogenic concentrations of vinflunine increase the interphase microtubule dynamics and decrease the motility of endothelial cells
-
Pourroy B, Honore S et al (2006) Antiangiogenic concentrations of vinflunine increase the interphase microtubule dynamics and decrease the motility of endothelial cells. Cancer Res 66(6):3256-3263.
-
(2006)
Cancer Res
, vol.66
, Issue.6
, pp. 3256-3263
-
-
Pourroy, B.1
Honore, S.2
-
81
-
-
0025789733
-
Phase I study of flavone acetic acid (NSC 347512, LM975) in patients with pediatric malignant solid tumors
-
Pratt CB, Relling MV et al (1991) Phase I study of flavone acetic acid (NSC 347512, LM975) in patients with pediatric malignant solid tumors. Am J Clin Oncol 14(6):483-486.
-
(1991)
Am J Clin Oncol
, vol.14
, Issue.6
, pp. 483-486
-
-
Pratt, C.B.1
Relling, M.V.2
-
82
-
-
0036779867
-
The vascular response of tumor and normal tissues in the rat to the vascular targeting agent, combretastatin A-4-phosphate, at clinically relevant doses
-
Prise VE, Honess DJ et al (2002) The vascular response of tumor and normal tissues in the rat to the vascular targeting agent, combretastatin A-4-phosphate, at clinically relevant doses. Int J Oncol 21(4):717-726.
-
(2002)
Int J Oncol
, vol.21
, Issue.4
, pp. 717-726
-
-
Prise, V.E.1
Honess, D.J.2
-
83
-
-
0024605005
-
Potential antitumor agents. 58. Synthesis and structureactivity relationships of substituted xanthenone-4-acetic acids active against the colon 38 tumor in vivo
-
Rewcastle GW, Atwell GJ et al (1989) Potential antitumor agents. 58. Synthesis and structureactivity relationships of substituted xanthenone-4-acetic acids active against the colon 38 tumor in vivo. J Med Chem 32(4):793-799.
-
(1989)
J Med Chem
, vol.32
, Issue.4
, pp. 793-799
-
-
Rewcastle, G.W.1
Atwell, G.J.2
-
84
-
-
33846041131
-
A phase 2 study of TZT-1027, administered weekly to patients with advanced non-small cell lung cancer following treatment with platinum-based chemotherapy
-
Riely GJ, Gadgeel S et al (2007) A phase 2 study of TZT-1027, administered weekly to patients with advanced non-small cell lung cancer following treatment with platinum-based chemotherapy. Lung Cancer 55(2):181-185.
-
(2007)
Lung Cancer
, vol.55
, Issue.2
, pp. 181-185
-
-
Riely, G.J.1
Gadgeel, S.2
-
85
-
-
18144432660
-
Phase I and pharmacokinetic study of TZT-1027, a novel synthetic dolastatin 10 derivative, administered as a 1-hour intravenous infusion every 3 weeks in patients with advanced refractory cancer
-
Schoffski P, Thate B et al (2004) Phase I and pharmacokinetic study of TZT-1027, a novel synthetic dolastatin 10 derivative, administered as a 1-hour intravenous infusion every 3 weeks in patients with advanced refractory cancer. Ann Oncol 15(4):671-679.
-
(2004)
Ann Oncol
, vol.15
, Issue.4
, pp. 671-679
-
-
Schoffski, P.1
Thate, B.2
-
86
-
-
33751360288
-
Reference profiling of the genomic response induced by an antimicrotubule agent, TZT-1027 (Soblidotin), in vitro
-
Shimoyama T, Hamano T et al (2006) Reference profiling of the genomic response induced by an antimicrotubule agent, TZT-1027 (Soblidotin), in vitro. Pharmacogenomics J 6(6):388-396.
-
(2006)
Pharmacogenomics J
, vol.6
, Issue.6
, pp. 388-396
-
-
Shimoyama, T.1
Hamano, T.2
-
87
-
-
0026575064
-
Phase II trial with flavone acetic acid (NSC.347512, LM975) in patients with non-small cell lung cancer
-
Siegenthaler P, Kaye SB et al (1992) Phase II trial with flavone acetic acid (NSC.347512, LM975) in patients with non-small cell lung cancer. Ann Oncol 3(2):169-170.
-
(1992)
Ann Oncol
, vol.3
, Issue.2
, pp. 169-170
-
-
Siegenthaler, P.1
Kaye, S.B.2
-
88
-
-
0036568457
-
Vascular targeting agents enhance chemotherapeutic agent activities in solid tumor therapy
-
Siemann DW, Mercer E et al (2002) Vascular targeting agents enhance chemotherapeutic agent activities in solid tumor therapy. Int J Cancer 99(1):1-6.
-
(2002)
Int J Cancer
, vol.99
, Issue.1
, pp. 1-6
-
-
Siemann, D.W.1
Mercer, E.2
-
89
-
-
0037222218
-
Marked potentiation of the antitumour activity of chemotherapeutic drugs by the antivascular agent 5,6-dimethylxanthenone-4-acetic acid (DMXAA)
-
Siim BG, Lee AE et al (2003) Marked potentiation of the antitumour activity of chemotherapeutic drugs by the antivascular agent 5,6-dimethylxanthenone-4-acetic acid (DMXAA). Cancer Chemother Pharmacol 51(1):43-52.
-
(2003)
Cancer Chemother Pharmacol
, vol.51
, Issue.1
, pp. 43-52
-
-
Siim, B.G.1
Lee, A.E.2
-
90
-
-
17144406367
-
Colchicine and 2-methoxyestradiol inhibit human angiogenesis
-
Stafford SJ, Schwimer J et al (2005) Colchicine and 2-methoxyestradiol inhibit human angiogenesis. J Surg Res 125(1):104-108.
-
(2005)
J Surg Res
, vol.125
, Issue.1
, pp. 104-108
-
-
Stafford, S.J.1
Schwimer, J.2
-
91
-
-
80052188022
-
Cardiovascular toxicity profiles of vascular-disrupting agents
-
Subbiah IM, Lenihan DJ et al (2011) Cardiovascular toxicity profiles of vascular-disrupting agents. Oncologist 16(8):1120-1130.
-
(2011)
Oncologist
, vol.16
, Issue.8
, pp. 1120-1130
-
-
Subbiah, I.M.1
Lenihan, D.J.2
-
92
-
-
34248374465
-
Phase I study of TZT-1027, a novel synthetic dolastatin 10 derivative and inhibitor of tubulin polymerization, which was administered to patients with advanced solid tumors on days 1 and 8 in 3-week courses
-
Tamura K, Nakagawa K et al (2007) Phase I study of TZT-1027, a novel synthetic dolastatin 10 derivative and inhibitor of tubulin polymerization, which was administered to patients with advanced solid tumors on days 1 and 8 in 3-week courses. Cancer Chemother Pharmacol 60(2):285-293.
-
(2007)
Cancer Chemother Pharmacol
, vol.60
, Issue.2
, pp. 285-293
-
-
Tamura, K.1
Nakagawa, K.2
-
93
-
-
0025094128
-
Evidence for the production of nitric oxide by activated macrophages treated with the antitumor agents flavone-8-acetic acid and xanthenone-4-acetic acid
-
Thomsen LL, Ching LM et al (1990) Evidence for the production of nitric oxide by activated macrophages treated with the antitumor agents flavone-8-acetic acid and xanthenone-4-acetic acid. Cancer Res 50(21):6966-6970.
-
(1990)
Cancer Res
, vol.50
, Issue.21
, pp. 6966-6970
-
-
Thomsen, L.L.1
Ching, L.M.2
-
94
-
-
0026089375
-
Tumor-dependent increased plasma nitrate concentrations as an indication of the antitumor effect of flavone-8-acetic acid and analogues in mice
-
Thomsen LL, Ching LM et al (1991) Tumor-dependent increased plasma nitrate concentrations as an indication of the antitumor effect of flavone-8-acetic acid and analogues in mice. Cancer Res 51(1):77-81.
-
(1991)
Cancer Res
, vol.51
, Issue.1
, pp. 77-81
-
-
Thomsen, L.L.1
Ching, L.M.2
-
95
-
-
0026773860
-
Nitric oxide production in endotoxin-resistant C3H/HeJ mice stimulated with flavone-8-acetic acid and xanthenone-4-acetic acid analogues
-
Thomsen LL, Ching LM et al (1992) Nitric oxide production in endotoxin-resistant C3H/HeJ mice stimulated with flavone-8-acetic acid and xanthenone-4-acetic acid analogues. Biochem Pharmacol 43(11):2401-2406.
-
(1992)
Biochem Pharmacol
, vol.43
, Issue.11
, pp. 2401-2406
-
-
Thomsen, L.L.1
Ching, L.M.2
-
96
-
-
0035417875
-
Mechanisms associated with tumor vascular shut-down induced by combretastatin A-4 phosphate: Intravital microscopy and measurement of vascular permeability
-
Tozer GM, Prise VE et al (2001) Mechanisms associated with tumor vascular shut-down induced by combretastatin A-4 phosphate: intravital microscopy and measurement of vascular permeability. Cancer Res 61(17):6413-6422.
-
(2001)
Cancer Res
, vol.61
, Issue.17
, pp. 6413-6422
-
-
Tozer, G.M.1
Prise, V.E.2
-
97
-
-
20344379950
-
Disrupting tumour blood vessels
-
Tozer GM, Kanthou C et al (2005) Disrupting tumour blood vessels. Nat Rev Cancer 5(6):423-435.
-
(2005)
Nat Rev Cancer
, vol.5
, Issue.6
, pp. 423-435
-
-
Tozer, G.M.1
Kanthou, C.2
-
98
-
-
0021272340
-
Current NCI preclinical antitumor screening in vivo: Results of tumor panel screening, 1976-1982, and future directions
-
Venditti JM, Wesley RA et al (1984) Current NCI preclinical antitumor screening in vivo: results of tumor panel screening, 1976-1982, and future directions. Adv Pharmacol Chemother 20:1-20.
-
(1984)
Adv Pharmacol Chemother
, vol.20
, pp. 1-20
-
-
Venditti, J.M.1
Wesley, R.A.2
-
99
-
-
78649948637
-
Therapeutic promises of 2-methoxyestradiol and its drug disposition challenges
-
Verenich S, Gerk PM (2010) Therapeutic promises of 2-methoxyestradiol and its drug disposition challenges. Mol Pharm 7(6):2030-2039.
-
(2010)
Mol Pharm
, vol.7
, Issue.6
, pp. 2030-2039
-
-
Verenich, S.1
Gerk, P.M.2
-
100
-
-
27644466314
-
Combretastatin A4 phosphate induces rapid regression of tumor neovessels and growth through interference with vascular endothelial-cadherin signaling
-
Vincent L, Kermani P et al (2005) Combretastatin A4 phosphate induces rapid regression of tumor neovessels and growth through interference with vascular endothelial-cadherin signaling. J Clin Invest 115(11):2992-3006.
-
(2005)
J Clin Invest
, vol.115
, Issue.11
, pp. 2992-3006
-
-
Vincent, L.1
Kermani, P.2
-
101
-
-
79959958353
-
Inhibition of tumor angiogenesis by antibodies, synthetic small molecules and natural products
-
Wahl O, Oswald M et al (2011) Inhibition of tumor angiogenesis by antibodies, synthetic small molecules and natural products. Curr Med Chem 18(21):3136-3155.
-
(2011)
Curr Med Chem
, vol.18
, Issue.21
, pp. 3136-3155
-
-
Wahl, O.1
Oswald, M.2
-
102
-
-
33750372682
-
Antivascular effects of TZT-1027 (Soblidotin) on murine Colon26 adenocarcinoma
-
Watanabe J, Natsume T et al (2006) Antivascular effects of TZT-1027 (Soblidotin) on murine Colon26 adenocarcinoma. Cancer Sci 97(12):1410-1416.
-
(2006)
Cancer Sci
, vol.97
, Issue.12
, pp. 1410-1416
-
-
Watanabe, J.1
Natsume, T.2
-
103
-
-
34047212221
-
Antiangiogenic activity of TZT-1027 (soblidotin) on chick chorioallantoic membrane and human umbilical vein endothelial cells
-
Watanabe J, Endo Y et al (2007) Antiangiogenic activity of TZT-1027 (soblidotin) on chick chorioallantoic membrane and human umbilical vein endothelial cells. In Vivo 21(2):297-304.
-
(2007)
In Vivo
, vol.21
, Issue.2
, pp. 297-304
-
-
Watanabe, J.1
Endo, Y.2
-
104
-
-
4544277194
-
Combretastatin A4 phosphate: Background and current clinical status
-
Young SL, Chaplin DJ (2004) Combretastatin A4 phosphate: background and current clinical status. Expert Opin Investig Drugs 13(9):1171-1182.
-
(2004)
Expert Opin Investig Drugs
, vol.13
, Issue.9
, pp. 1171-1182
-
-
Young, S.L.1
Chaplin, D.J.2
-
105
-
-
42149144179
-
Vinflunine: Clinical perspectives of an emerging anticancer agent
-
Yun-San Yip A, Yuen-Yuen Ong E et al (2008) Vinflunine: clinical perspectives of an emerging anticancer agent. Expert Opin Investig Drugs 17(4):583-591.
-
(2008)
Expert Opin Investig Drugs
, vol.17
, Issue.4
, pp. 583-591
-
-
Yun-san Yip, A.1
Yuen-yuen Ong, E.2
-
106
-
-
0037068317
-
The antitumour activity of 5,6-dimethylxanthenone-4-acetic acid (DMXAA) in TNF receptor-1 knockout mice
-
Zhao L, Ching LM et al (2002) The antitumour activity of 5,6-dimethylxanthenone-4-acetic acid (DMXAA) in TNF receptor-1 knockout mice. Br J Cancer 87(4):465-470.
-
(2002)
Br J Cancer
, vol.87
, Issue.4
, pp. 465-470
-
-
Zhao, L.1
Ching, L.M.2
-
107
-
-
22044437369
-
Mechanisms of tumor vascular shutdown induced by 5,6-dimethylxanthenone-4-acetic acid (DMXAA): Increased tumor vascular permeability
-
Zhao L, Ching LM et al (2005) Mechanisms of tumor vascular shutdown induced by 5,6-dimethylxanthenone-4-acetic acid (DMXAA): increased tumor vascular permeability. Int J Cancer 116(2):322-326.
-
(2005)
Int J Cancer
, vol.116
, Issue.2
, pp. 322-326
-
-
Zhao, L.1
Ching, L.M.2
-
108
-
-
0024335180
-
Blood flow failure as a major determinant in the antitumor action of flavone acetic acid
-
Zwi LJ, Baguley BC et al (1989) Blood flow failure as a major determinant in the antitumor action of flavone acetic acid. J Natl Cancer Inst 81(13):1005-1013.
-
(1989)
J Natl Cancer Inst
, vol.81
, Issue.13
, pp. 1005-1013
-
-
Zwi, L.J.1
Baguley, B.C.2
-
109
-
-
0028124643
-
Correlation between immune and vascular activities of xanthenone acetic acid antitumor agents
-
Zwi LJ, Baguley BC et al (1994) Correlation between immune and vascular activities of xanthenone acetic acid antitumor agents. Oncol Res 6(2):79-85.
-
(1994)
Oncol Res
, vol.6
, Issue.2
, pp. 79-85
-
-
Zwi, L.J.1
Baguley, B.C.2
|