Determinants of anti-vascular action by combretastatin A-4 phosphate: Role of nitric oxide

British Journal of Cancer

Volumn 83, Issue 6, 2000, Pages 811-816

  Parkins, C S ^a   Holder, A L ^a   Hill, S A ^a   Chaplin, D J ^a,b   Tozer, G M ^a  

^a MOUNT VERNON HOSPITAL   (United Kingdom)

^b SANOFI   (France)

Author keywords

Combretastatin A 4 phosphate; Neutrophil; Nitric oxide; Vasculature

Indexed keywords

COMBRETASTATIN A4; DIETHYLAMINE; MYELOPEROXIDASE; N(G) NITROARGININE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE INHIBITOR;

ANIMAL CELL; ARTICLE; BLOOD VESSEL INJURY; BREAST ADENOCARCINOMA; CELL INFILTRATION; CELL PROTECTION; CYTOTOXICITY; ENZYME ACTIVITY; FEMALE; MOUSE; NEUTROPHIL; NONHUMAN; PRIORITY JOURNAL; SARCOMA CELL; TUMOR VASCULARIZATION;

EID: 0033817283     PISSN: 00070920     EISSN: None     Source Type: Journal    
DOI: 10.1054/bjoc.2000.1361     Document Type: Article

References (33)

1. Conversion of xanthine dehydrogenase to xanthine oxidase as a possible marker for hypoxia in tumours and normal tissues
2. Method for the quantitative morphologic analysis of tissues
3. Antivascular approaches to solid tumour therapy: Evaluation of tubulin binding agents
4. Anti-vascular approaches to solid tumour therapy: Evaluation of combretastatin A4 phosphate
5. Combretastatin A-4, an agent that displays potent and selective toxicity toward tumor vasculature
6. Formation of nitrating and chlorinating species by reaction of nitrite with hypochlorous acid
7. Formation of nitric oxide derived inflammatory oxidants by myeloperoxidase in neutrophils
8. Microtubule dysfunction by post-translational nitrotyrosination of α-tubulin: A nitric oxide-dependent mechanism of cellular injury
9. What is the evidence that tumors are angiogenic dependent?
10. Xanthine oxidase and neutrophil infiltration in intestinal ischaemia
11. In vivo and in vitro evaluation of combretastatin A-4 and its sodium phosphate prodrug
12. Antivascular approaches to solid tumour therapy: Evaluation of vinblastine and flavone acetic acid
13. The effect of combretastatin A-4 disodium phosphate in a C3H mouse mammary carcinoma and a variety of murine spontaneous tumors
14. Free-radical enhancement promotes leukocyte recruitment through a PAF and LTB4 dependent mechanism
15. Induction of apoptosis in proliferating human endothelial cells by the tumor-specific anti-angiogenesis agent Combretastatin A-4
16. Myeloperoxidase: A key regulator of neutrophil oxidant production
17. Peroxynitrite and myeloperoxidase leave the stone footprint in protein nitration
18. The role of nitric oxide in the response of cancerous lesions to photodynamic therapy
19. Nitric oxide production by tumour tissue: Impact on the response to photodynamic therapy
20. Nitric oxide: An endogenous modulator of leukocyte adhesion
21. Ischaemia induced cell death in tumours: Importance of temperature and pH
22. Ischaemia-reperfusion injury in solid tumors: The role of oxygen radicals and nitric oxide
23. Metabolic and clonogenic consequences of ischaemia-reperfusion insult in solid tumours
24. Involvement of oxygen free radicals in ischaemia-reperfusion injury in murine tumours: Role of nitric oxide
25. Isolation and structure of the strong cell growth and tubulin inhibitor combretastatin A-4
26. Assembly and colchicine binding characteristics of tubulin with maximally tyrosinated and detyrosinated α-tubulins
27. Combretastatin A-4 phosphate as a tumor vascular-targeting agent: Early effects in tumors and normal tissues
28. Use of a carbocyanine dye as a marker of functional vasculature in murine tumours
29. Formation of reactive nitrogen species during peroxidase-catalysed oxidation of nitrite
30. Effects of novel and conventional anti-cancer agents on human endothelial permeability: Influence of tumour secreted factors
31. The interaction with tubulin of a series of stilbenes based on combretastatin A-4
32. Nitric oxide protects against cellular damage and cytotoxicity from reactive oxygen species
33. The role of neutrophils in reperfusion injury