Induction of endothelial cell apoptosis by the antivascular agent 5, 6-dimethylxanthenone-4-acetic acid

British Journal of Cancer

Volumn 86, Issue 12, 2002, Pages 1937-1942

  Ching, L M ^a   Cao, Z ^a   Kieda, C ^b   Zwain, S ^a   Jameson, M B ^a   Baguley, B C ^a  

^a UNIVERSITY OF AUCKLAND   (New Zealand)

^b CENTRE DE BIOPHYSIQUE MOLÉCULAIRE   (France)

Author keywords

Antivascular; Apoptosis; Colon 38 tumour; DMXAA; Endothelial

Indexed keywords

5,6 DIMETHYLXANTHENON 4 ACETIC ACID; 8 METHYLXANTHENON 4 ACETIC ACID; ACETIC ACID DERIVATIVE; ANGIOGENESIS INHIBITOR; MESSENGER RNA; TUMOR NECROSIS FACTOR; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL DEATH; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; DOSE RESPONSE; DRUG EFFECT; DRUG MECHANISM; ENDOTHELIUM CELL; HUMAN; HUMAN TISSUE; MOUSE; NICK END LABELING; NONHUMAN; PHASE 1 CLINICAL TRIAL; PRIORITY JOURNAL; TUMOR BIOPSY; VASCULAR ENDOTHELIUM;

ADENOCARCINOMA; ANIMALS; ANTINEOPLASTIC AGENTS; APOPTOSIS; BLOTTING, NORTHERN; BREAST NEOPLASMS; CELLS, CULTURED; CHEMOKINES, CXC; COLONIC NEOPLASMS; ENDOTHELIUM, VASCULAR; FEMALE; HUMANS; INTERFERONS; MICE; MICE, INBRED C57BL; OVARIAN NEOPLASMS; RNA, MESSENGER; TUMOR NECROSIS FACTOR-ALPHA; XANTHENES; XANTHONES;

EID: 0037125028     PISSN: 00070920     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjc.6600368     Document Type: Article

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