Phase II study of intravenous TZT-1027 in patients with advanced or metastatic soft-tissue sarcomas with prior exposure to anthracycline-based chemotherapy

Cancer

Volumn 107, Issue 12, 2006, Pages 2881-2887

  Patel, Shreyaskumar ^a   Keohan, Mary Louise ^b   Saif, M Wasif ^c   Rushing, Daniel ^d   Baez, Luis ^e   Feit, Kevie ^f   DeJager, Robert ^f   Anderson, Sibyl ^g  

^a UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

^b New York Presbyterian Hospital Columbia University Medical Center   (United States)

^c UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^d INDIANA UNIVERSITY   (United States)

^e VA MEDICAL CENTER   (Puerto Rico)

^f Daiichi Medical Research   (United States)

^g MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

Author keywords

Metastatic soft tissue sarcoma; Phase II study; Response; Toxicity evaluation; TZT 1027

Indexed keywords

ANTHRACYCLINE DERIVATIVE; ANTINEOPLASTIC AGENT; AURISTATIN PE;

ADULT; ADVANCED CANCER; AGED; ALOPECIA; ANEMIA; ARTICLE; CANCER CHEMOTHERAPY; CANCER SURVIVAL; CLINICAL ARTICLE; CLINICAL TRIAL; COMPUTER ASSISTED TOMOGRAPHY; CONSTIPATION; DIARRHEA; DRUG DOSE ESCALATION; DRUG EFFICACY; DYSPNEA; FATIGUE; FEMALE; FOLLOW UP; HUMAN; INFUSION PUMP; INJECTION SITE PAIN; LEUKOPENIA; LIMB PAIN; MALE; METASTASIS; MONOTHERAPY; MULTICENTER STUDY; MULTIPLE CYCLE TREATMENT; MYALGIA; NAUSEA; NEUTROPENIA; NUCLEAR MAGNETIC RESONANCE IMAGING; PHASE 2 CLINICAL TRIAL; PRIORITY JOURNAL; SOFT TISSUE SARCOMA; THORAX RADIOGRAPHY; THROMBOCYTOPENIA; TREATMENT OUTCOME;

ADULT; AGED; ANTHRACYCLINES; ANTINEOPLASTIC AGENTS; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; CONSTIPATION; FATIGUE; FEMALE; HUMANS; INJECTIONS, INTRAVENOUS; MALE; MIDDLE AGED; NEUTROPENIA; OLIGOPEPTIDES; SARCOMA;

EID: 33845582571     PISSN: 0008543X     EISSN: 10970142     Source Type: Journal    
DOI: 10.1002/cncr.22334     Document Type: Article

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