Genome-wide DNA methylation analysis identifies a metabolic memory profile in patient-derived diabetic foot ulcer fibroblasts

Epigenetics

Volumn 9, Issue 10, 2014, Pages 1339-1349

  Park, Lara K ^a   Maione, Anna G ^b   Smith, Avi ^a   Gerami Naini, Behzad ^a   Iyer, Lakshmanan K ^c,d   Mooney, David J ^e,f   Veves, Aristidis ^g   Garlick, Jonathan A ^a,b  

^a TUFTS UNIVERSITY SCHOOL OF DENTAL MEDICINE   (United States)

^b TUFTS UNIVERSITY   (United States)

^c TUFTS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d TUFTS MEDICAL CENTER   (United States)

^e HARVARD UNIVERSITY   (United States)

^f HARVARD UNIVERSITY   (United States)

^g HARVARD MEDICAL SCHOOL   (United States)

Author keywords

Diabetes; Diabetic foot ulcer; DNA methylation; Epigenetics; Fibroblast; Metabolic memory; Wound healing

Indexed keywords

HEMOGLOBIN A1C; MYC PROTEIN; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR ALPHA;

ADULT; AGED; ANGIOGENESIS; ARTICLE; BIOINFORMATICS; CLINICAL ARTICLE; CONTROLLED STUDY; DIABETIC FOOT; DIABETIC FOOT FIBROBLAST; DNA METHYLATION; EXTRACELLULAR MATRIX; FEMALE; FIBROBLAST; GENE EXPRESSION; GENETIC ANALYSIS; GLUCOSE BLOOD LEVEL; HUMAN; LIQUID CHROMATOGRAPHY; MALE; MASS SPECTROMETRY; MIDDLE AGED; WOUND HEALING; BIOLOGY; CELL LINE; GENETIC EPIGENESIS; GENETICS; METABOLISM;

ADULT; AGED; CELL LINE; COMPUTATIONAL BIOLOGY; DIABETIC FOOT; DNA METHYLATION; EPIGENESIS, GENETIC; FEMALE; FIBROBLASTS; HUMANS; MALE; MIDDLE AGED;

EID: 84922065481     PISSN: 15592294     EISSN: 15592308     Source Type: Journal    
DOI: 10.4161/15592294.2014.967584     Document Type: Article

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