Regulation of DNA methyltransferase 1 transcription in BRCA1-mutated breast cancer: A novel crosstalk between E2F1 motif hypermethylation and loss of histone H3 lysine 9 acetylation

Molecular Cancer

Volumn 13, Issue 1, 2014, Pages

  Li, Da ^a   Bi, Fang Fang ^a   Cao, Ji Min ^b   Cao, Chen ^c   Liu, Bo ^a   Yang, Qing ^a  

^a CHINA MEDICAL UNIVERSITY   (China)

^b INSTITUTE OF BASIC MEDICAL SCIENCES   (China)

^c CHINESE PLA GENERAL HOSPITAL   (China)

Author keywords

BRCA1; Breast cancer; DNMT1; E2F1; Histone modifications

Indexed keywords

BRCA1 PROTEIN; DNA METHYLTRANSFERASE 1; EPIDERMAL GROWTH FACTOR RECEPTOR 2; ESTROGEN RECEPTOR; H3K18AC PROTEIN; H3K27AC PROTEIN; H3K27ME PROTEIN; H3K27ME2 PROTEIN; H3K27ME3 PROTEIN; H3K36ME3 PROTEIN; H3K4ME1 PROTEIN; H3K4ME2 PROTEIN; H3K4ME3 PROTEIN; H3K79ME PROTEIN; H3K9ME PROTEIN; H3K9ME2 PROTEIN; H3K9ME3 PROTEIN; HISTONE H3; HISTONE H3 LYSINE 9 ACETYLATION; PROGESTERONE RECEPTOR; PROTEIN P53; TRANSCRIPTION FACTOR E2F1; UNCLASSIFIED DRUG; UVOMORULIN;

ADULT; ARTICLE; BREAST CARCINOMA; CANCER GROWTH; CANCER PROGNOSIS; CANCER SURVIVAL; CLINICAL FEATURE; CONTROLLED STUDY; DNA METHYLATION; FEMALE; GENE MUTATION; HISTONE ACETYLATION; HISTONE MODIFICATION; HUMAN; HUMAN CELL; LYMPH NODE METASTASIS; OVERALL SURVIVAL; PROMOTER REGION; PROTEIN DEPLETION; PROTEIN EXPRESSION; PROTEIN MOTIF; TRANSCRIPTION INITIATION SITE; TRANSCRIPTION REGULATION;

ACETYLATION; ADULT; AGED; BREAST NEOPLASMS; CARCINOMA, DUCTAL, BREAST; CHROMATIN IMMUNOPRECIPITATION; CIRCULAR DICHROISM; DNA (CYTOSINE-5-)-METHYLTRANSFERASE; DNA METHYLATION; E2F1 TRANSCRIPTION FACTOR; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; GENES, BRCA1; HISTONES; HUMANS; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; IMMUNOPRECIPITATION; KAPLAN-MEIER ESTIMATE; LYSINE; MIDDLE AGED; MUTATION; PROGNOSIS; PROPORTIONAL HAZARDS MODELS; REAL-TIME POLYMERASE CHAIN REACTION; RECEPTOR CROSS-TALK; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TRANSCRIPTION, GENETIC;

EID: 84896716895     PISSN: None     EISSN: 14764598     Source Type: Journal    
DOI: 10.1186/1476-4598-13-26     Document Type: Article

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