Dichloroacetate affects proliferation but not survival of human colorectal cancer cells

Apoptosis

Volumn 20, Issue 1, 2015, Pages 63-74

  Delaney, L M ^a   Ho, N ^a   Morrison, J ^a   Farias, N R ^a   Mosser, D D ^a   Coomber, B L ^a  

^a UNIVERSITY OF GUELPH   (Canada)

Author keywords

Bax; Colorectal cancer; Dichloroacetate; Mcl 1; p53

Indexed keywords

BAG 1 PROTEIN; CASPASE 3; DICHLOROACETIC ACID; FLUOROURACIL; PROTEIN BAD; PROTEIN BAX; PROTEIN BCL 2; PROTEIN BCL X; PROTEIN BID; PROTEIN MCL 1; PROTEIN P53; PYRUVATE DEHYDROGENASE; ANTIMETABOLITE; BAX PROTEIN, HUMAN; BENZYLOXYCARBONYLLEUCYL-LEUCYL-LEUCINE ALDEHYDE; CYSTEINE PROTEINASE INHIBITOR; LEUPEPTIN; MCL1 PROTEIN, HUMAN;

APOPTOSIS; ARTICLE; CANCER GROWTH; CANCER INHIBITION; CELL COUNT; CELL FRACTIONATION; CELL GROWTH; CELL PROLIFERATION; CELL VIABILITY; COLORECTAL CANCER CELL LINE; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOSOLIC FRACTION; DOWN REGULATION; ENZYMATIC DEGRADATION; ENZYME PHOSPHORYLATION; GROWTH RATE; HCT116 CELL LINE; HUMAN; HUMAN CELL; IC50; IN VITRO STUDY; PRIORITY JOURNAL; PROTEIN DEPLETION; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; CELL CYCLE; CELL SURVIVAL; COLORECTAL NEOPLASMS; DRUG EFFECTS; GENE INACTIVATION; GENETICS; METABOLISM; PATHOLOGY; PHOSPHORYLATION;

ANTIMETABOLITES; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; CELL CYCLE; CELL PROLIFERATION; CELL SURVIVAL; COLORECTAL NEOPLASMS; CYSTEINE PROTEINASE INHIBITORS; DICHLOROACETIC ACID; GENE KNOCKOUT TECHNIQUES; HCT116 CELLS; HUMANS; LEUPEPTINS; MYELOID CELL LEUKEMIA SEQUENCE 1 PROTEIN; PHOSPHORYLATION; TUMOR SUPPRESSOR PROTEIN P53;

EID: 84922005457     PISSN: 13608185     EISSN: 1573675X     Source Type: Journal    
DOI: 10.1007/s10495-014-1046-4     Document Type: Article

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