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Volumn 58, Issue 2, 2012, Pages 102-109

Short-chain fatty acids induce apoptosis in colon cancer cells associated with changes to intracellular redox state and glucose metabolism

Author keywords

Apoptosis; Butyrate; Cell cycle; Colon cancer; Glucose metabolism; Propionate; Redox; Short chain fatty acid

Indexed keywords

BUTYRIC ACID; GLUTATHIONE; PROPIONIC ACID; REACTIVE OXYGEN METABOLITE;

EID: 84859407617     PISSN: 00093157     EISSN: 14219794     Source Type: Journal    
DOI: 10.1159/000335672     Document Type: Article
Times cited : (62)

References (43)
  • 2
    • 25444472340 scopus 로고    scopus 로고
    • The histone deacetylase inhibitor butyrate downregulates cyclin B1 gene expression via a p21/WAF-1-dependent mechanism in human colon cancer cells
    • Archer SY, Johnson J, Kim H-J, Ma Q, Mou H, Daesety V, Meng S, Hodin RA: The histone deacetylase inhibitor butyrate downregulates cyclin B1 gene expression via a p21/WAF-1-dependent mechanism in human colon cancer cells. Am J Physiol Gastrointest Liver Physiol 2005; 289:G696-G703.
    • (2005) Am J Physiol Gastrointest Liver Physiol , vol.289
    • Archer, S.Y.1    Johnson, J.2    Kim, H.-J.3    Ma, Q.4    Mou, H.5    Daesety, V.6    Meng, S.7    Hodin, R.A.8
  • 3
    • 0031564105 scopus 로고    scopus 로고
    • 5-Fluorouracil-resistant colonic tumors are highly responsive to sodium butyrate/interleukin-2 bitherapy in rats
    • Corde S, Heymann MF, Boisteau O, Oliver L, Le Pendu J, Gregoire M, Meflah K: 5-Fluorouracil-resistant colonic tumors are highly responsive to sodium butyrate/interleukin-2 bitherapy in rats. Int J Cancer 1997; 73: 924-928.
    • (1997) Int J Cancer , vol.73 , pp. 924-928
    • Corde, S.1    Heymann, M.F.2    Boisteau, O.3    Oliver, L.4    Le Pendu, J.5    Gregoire, M.6    Meflah, K.7
  • 4
    • 20744452605 scopus 로고    scopus 로고
    • Dietary fibre and colorectal cancer: A model for environment-gene interactions
    • Young GP, Hu Y, Le Leu RK, Nyskohus L: Dietary fibre and colorectal cancer: a model for environment-gene interactions. Mol Nutr Food Res 2005; 49: 571-584.
    • (2005) Mol Nutr Food Res , vol.49 , pp. 571-584
    • Young, G.P.1    Hu, Y.2    Le Leu, R.K.3    Nyskohus, L.4
  • 5
    • 33746233585 scopus 로고    scopus 로고
    • Dietary fiber enhances a tumor suppressor signaling pathway in the gut
    • Nguyen KA, Cao Y, Chen JR, Townsend CM, Ko TC: Dietary fiber enhances a tumor suppressor signaling pathway in the gut. Ann Surg 2006; 243: 619-625.
    • (2006) Ann Surg , vol.243 , pp. 619-625
    • Nguyen, K.A.1    Cao, Y.2    Chen, J.R.3    Townsend, C.M.4    Ko, T.C.5
  • 6
    • 44349149886 scopus 로고    scopus 로고
    • Butyrate and Wnt signaling: A possible solution to the puzzle of dietary fiber and colon cancer risk?
    • Bordonaro M, Lazarova DL, Sartorelli AC: Butyrate and Wnt signaling: a possible solution to the puzzle of dietary fiber and colon cancer risk? Cell Cycle 2008; 7: 1178-1183.
    • (2008) Cell Cycle , vol.7 , pp. 1178-1183
    • Bordonaro, M.1    Lazarova, D.L.2    Sartorelli, A.C.3
  • 7
    • 54949115052 scopus 로고    scopus 로고
    • Modulation of intestinal environment by prebiotic germinated barley foodstuff prevents chemo-induced colonic carcinogenesis in rats
    • Kanauchi O, Mitsuyama K, Andoh A, Iwanaga T: Modulation of intestinal environment by prebiotic germinated barley foodstuff prevents chemo-induced colonic carcinogenesis in rats. Oncol Rep 2008; 20: 793-801.
    • (2008) Oncol Rep , vol.20 , pp. 793-801
    • Kanauchi, O.1    Mitsuyama, K.2    Andoh, A.3    Iwanaga, T.4
  • 8
    • 35848936502 scopus 로고    scopus 로고
    • Dietary modulation of colon cancer risk
    • Kim YS, Milner JA: Dietary modulation of colon cancer risk. J Nutr 2007; 137(suppl 11):S2576-S2579.
    • (2007) J Nutr , vol.137 , Issue.SUPPL. 11
    • Kim, Y.S.1    Milner, J.A.2
  • 9
    • 0035126973 scopus 로고    scopus 로고
    • Resistance to butyrate-induced cell differentiation and apoptosis during spontaneous Caco-2 cell differentiation
    • Mariadason JM, Velcich A, Wilson AJ, Augenlicht LH, Gibson PR: Resistance to butyrate-induced cell differentiation and apoptosis during spontaneous Caco-2 cell differentiation. Gastroenterology 2001; 120: 889-899.
    • (2001) Gastroenterology , vol.120 , pp. 889-899
    • Mariadason, J.M.1    Velcich, A.2    Wilson, A.J.3    Augenlicht, L.H.4    Gibson, P.R.5
  • 10
    • 30644463203 scopus 로고    scopus 로고
    • Microarray analysis of butyrate regulated genes in colonic epithelial cells
    • Daly K, Shirazi-Beechey SP: Microarray analysis of butyrate regulated genes in colonic epithelial cells. DNA Cell Biol 2006; 25: 49-62.
    • (2006) DNA Cell Biol , vol.25 , pp. 49-62
    • Daly, K.1    Shirazi-Beechey, S.P.2
  • 11
  • 12
    • 0346725848 scopus 로고    scopus 로고
    • The effect of specific caspase inhibitors on TNF-alpha and butyrate-induced apoptosis of intestinal epithelial cells
    • Jones SA, Butler RN, Sanderson IA, Wilson JW: The effect of specific caspase inhibitors on TNF-alpha and butyrate-induced apoptosis of intestinal epithelial cells. Exp Cell Res 2004; 292: 29-39.
    • (2004) Exp Cell Res , vol.292 , pp. 29-39
    • Jones, S.A.1    Butler, R.N.2    Sanderson, I.A.3    Wilson, J.W.4
  • 13
    • 38149113293 scopus 로고    scopus 로고
    • Short-chain fatty acid modulation of apoptosis in the Kato III human gastric carcinoma cell line
    • Matthews GM, Howarth GS, Butler RN: Short-chain fatty acid modulation of apoptosis in the Kato III human gastric carcinoma cell line. Cancer Biol Ther 2007; 6: 1051-1057.
    • (2007) Cancer Biol Ther , vol.6 , pp. 1051-1057
    • Matthews, G.M.1    Howarth, G.S.2    Butler, R.N.3
  • 14
    • 44449140859 scopus 로고    scopus 로고
    • Mechanisms of ROS modulated cell survival during carcinogenesis
    • Clerkin JS, Naughton R, Quiney C, Cotter TG: Mechanisms of ROS modulated cell survival during carcinogenesis. Cancer Lett 2008; 266: 30-36.
    • (2008) Cancer Lett , vol.266 , pp. 30-36
    • Clerkin, J.S.1    Naughton, R.2    Quiney, C.3    Cotter, T.G.4
  • 15
    • 53049104546 scopus 로고    scopus 로고
    • Manipulation of oxidative stress to induce cell death in Ewing's sarcoma family of tumours
    • Magwere T, Myatt SS, Burchill SA: Manipulation of oxidative stress to induce cell death in Ewing's sarcoma family of tumours. Eur J Cancer 2008; 44: 2276-2287.
    • (2008) Eur J Cancer , vol.44 , pp. 2276-2287
    • Magwere, T.1    Myatt, S.S.2    Burchill, S.A.3
  • 16
    • 53049102297 scopus 로고    scopus 로고
    • Decreasing peroxiredoxin II expression decreases glutathione, alters cell cycle distribution, and sensitizes glioma cells to ionizing radiation and H(2)O(2)
    • Smith-Pearson PS, Kooshki M, Spitz DR, Poole LB, Zhao W, Robbins ME: Decreasing peroxiredoxin II expression decreases glutathione, alters cell cycle distribution, and sensitizes glioma cells to ionizing radiation and H(2)O(2). Free Radic Biol Med 2008; 45: 1178-1189.
    • (2008) Free Radic Biol Med , vol.45 , pp. 1178-1189
    • Smith-Pearson, P.S.1    Kooshki, M.2    Spitz, D.R.3    Poole, L.B.4    Zhao, W.5    Robbins, M.E.6
  • 18
    • 44649152084 scopus 로고    scopus 로고
    • Ornithine decarboxylase attenuates leukemic chemotherapy drugs-induced cell apoptosis and arrest in human promyelocytic HL-60 cells
    • Hsu PC, Hung HC, Liao YF, Liu CC, Tsay GJ, Liu GY: Ornithine decarboxylase attenuates leukemic chemotherapy drugs-induced cell apoptosis and arrest in human promyelocytic HL-60 cells. Leuk Res 2008; 32: 208-221.
    • (2008) Leuk Res , vol.32 , pp. 208-221
    • Hsu, P.C.1    Hung, H.C.2    Liao, Y.F.3    Liu, C.C.4    Tsay, G.J.5    Liu, G.Y.6
  • 19
    • 34548129941 scopus 로고    scopus 로고
    • The mode of cisplatin-induced cell death in CYP2E1-overexpressing HepG2 cells: Modulation by ERK, ROS, glutathione, and thioredoxin
    • Lu Y, Cederbaum A: The mode of cisplatin-induced cell death in CYP2E1-overexpressing HepG2 cells: modulation by ERK, ROS, glutathione, and thioredoxin. Free Radic Biol Med 2007; 43: 1061-1075.
    • (2007) Free Radic Biol Med , vol.43 , pp. 1061-1075
    • Lu, Y.1    Cederbaum, A.2
  • 20
    • 42649140547 scopus 로고    scopus 로고
    • Inhibition of the EGF receptor blocks autocrine growth and increases the cytotoxic effects of doxorubicin in rat hepatoma cells: Role of reactive oxygen species production and glutathione depletion
    • Ortiz C, Caja L, Sancho P, Bertran E, Fabregat I: Inhibition of the EGF receptor blocks autocrine growth and increases the cytotoxic effects of doxorubicin in rat hepatoma cells: role of reactive oxygen species production and glutathione depletion. Biochem Pharmacol 2008; 75: 1935-1945.
    • (2008) Biochem Pharmacol , vol.75 , pp. 1935-1945
    • Ortiz, C.1    Caja, L.2    Sancho, P.3    Bertran, E.4    Fabregat, I.5
  • 21
    • 58149471362 scopus 로고    scopus 로고
    • Neutrophil infiltration and oxidative stress may play a critical role in methotrexate-induced renal damage
    • Viswa KK, Bina I, Dhayakani S: Neutrophil infiltration and oxidative stress may play a critical role in methotrexate-induced renal damage. Chemotherapy 2009; 55: 83-90.
    • (2009) Chemotherapy , vol.55 , pp. 83-90
    • Viswa, K.K.1    Bina, I.2    Dhayakani, S.3
  • 23
    • 58249089741 scopus 로고    scopus 로고
    • Colon cancer cells maintain low levels of pyruvate to avoid cell death caused by inhibition of HDAC1/HDAC3
    • Thangaraju M, Carswell KN, Prasad PD, Ganapathy V: Colon cancer cells maintain low levels of pyruvate to avoid cell death caused by inhibition of HDAC1/HDAC3. Biochem J 2009; 417: 379-389.
    • (2009) Biochem J , vol.417 , pp. 379-389
    • Thangaraju, M.1    Carswell, K.N.2    Prasad, P.D.3    Ganapathy, V.4
  • 26
    • 0021027358 scopus 로고
    • Detection of picomole levels of hydroperoxides using a fluorescent dichlorofluorescein assay
    • Cathcart R, Schwiers E, Ames BN: Detection of picomole levels of hydroperoxides using a fluorescent dichlorofluorescein assay. Anal Biochem 1983; 134: 111-116.
    • (1983) Anal Biochem , vol.134 , pp. 111-116
    • Cathcart, R.1    Schwiers, E.2    Ames, B.N.3
  • 27
    • 4444234434 scopus 로고    scopus 로고
    • Effect of short-chain fatty acids on the proliferation and differentiation of the human colonic adenocarcinoma cell line Caco-2
    • Fu H, Shi YQ, Mo SJ: Effect of short-chain fatty acids on the proliferation and differentiation of the human colonic adenocarcinoma cell line Caco-2. Chin J Dig Dis 2004; 5: 115-117.
    • (2004) Chin J Dig Dis , vol.5 , pp. 115-117
    • Fu, H.1    Shi, Y.Q.2    Mo, S.J.3
  • 28
    • 0031968953 scopus 로고    scopus 로고
    • Short-chain fatty acids induce cell cycle inhibitors in colonocytes
    • Wang J, Friedman EA: Short-chain fatty acids induce cell cycle inhibitors in colonocytes. Gastroenterology 1998; 114: 940-946.
    • (1998) Gastroenterology , vol.114 , pp. 940-946
    • Wang, J.1    Friedman, E.A.2
  • 29
    • 33646166955 scopus 로고    scopus 로고
    • Sodium butyrate induces apoptosis and cell cycle arrest in primary effusion lymphoma cells independently of oxidative stress and p21CIP/WAF1 induction
    • Wang Y-F, Chen N-S, Chung Y-P, Chang L-H, Chiou Y-H, Chen C-Y: Sodium butyrate induces apoptosis and cell cycle arrest in primary effusion lymphoma cells independently of oxidative stress and p21CIP/WAF1 induction. Mol Cell Biochem 2006; 285: 51-59.
    • (2006) Mol Cell Biochem , vol.285 , pp. 51-59
    • Wang, Y.-F.1    Chen, N.-S.2    Chung, Y.-P.3    Chang, L.-H.4    Chiou, Y.-H.5    Chen, C.-Y.6
  • 30
    • 22344443983 scopus 로고    scopus 로고
    • Butyrate may enhance toxicological defence in primary, adenoma and tumor colon cells by favourably modulating expression of glutathione S-transferases genes, an approach in nutrigenomics
    • Pool-Zobel BL, Selvaraju V, Sauer J, Kautenburger T, Kiefer J, Richter KK, Soom M, Wölfl S: Butyrate may enhance toxicological defence in primary, adenoma and tumor colon cells by favourably modulating expression of glutathione S-transferases genes, an approach in nutrigenomics. Carcinogenesis 2005; 26: 1064-1076.
    • (2005) Carcinogenesis , vol.26 , pp. 1064-1076
    • Pool-Zobel, B.L.1    Selvaraju, V.2    Sauer, J.3    Kautenburger, T.4    Kiefer, J.5    Richter, K.K.6    Soom, M.7    Wölfl, S.8
  • 34
    • 14944375437 scopus 로고    scopus 로고
    • The histone deacetylase inhibitor sodium butyrate induces breast cancer cell apoptosis through diverse cytotoxic actions including glutathione depletion and oxidative stress
    • Louis M, Rosato RR, Brault L, Osbild S, Battaglia E, Yang XH, Grant S, Bagrel D: The histone deacetylase inhibitor sodium butyrate induces breast cancer cell apoptosis through diverse cytotoxic actions including glutathione depletion and oxidative stress. Int J Oncol 2004; 25: 1701-1711.
    • (2004) Int J Oncol , vol.25 , pp. 1701-1711
    • Louis, M.1    Rosato, R.R.2    Brault, L.3    Osbild, S.4    Battaglia, E.5    Yang, X.H.6    Grant, S.7    Bagrel, D.8
  • 37
    • 0030974571 scopus 로고    scopus 로고
    • Modulation of glutathione level during butyrate-induced differentiation in human colon derived HT-29 cells
    • Benard O, Balasubramanian KA: Modulation of glutathione level during butyrate-induced differentiation in human colon derived HT-29 cells. Mol Cell Biochem 1997; 170: 109-114.
    • (1997) Mol Cell Biochem , vol.170 , pp. 109-114
    • Benard, O.1    Balasubramanian, K.A.2
  • 39
    • 33745767973 scopus 로고    scopus 로고
    • Nutrient and antioxidant modulation of apoptosis in gastric and colon cancer cells
    • Matthews GM, Howarth GS, Butler RN: Nutrient and antioxidant modulation of apoptosis in gastric and colon cancer cells. Cancer Biol Ther 2006; 5: 569-572.
    • (2006) Cancer Biol Ther , vol.5 , pp. 569-572
    • Matthews, G.M.1    Howarth, G.S.2    Butler, R.N.3
  • 40
    • 33744788610 scopus 로고    scopus 로고
    • Toxic and metabolic effect of sodium butyrate on SAS tongue cancer cells: Role of cell cycle deregulation and redox changes
    • Jeng JH, Kuo MY, Lee PH, Wang YJ, Lee MY, Lee JJ, Lin BR, Tai TF, Chang MC: Toxic and metabolic effect of sodium butyrate on SAS tongue cancer cells: role of cell cycle deregulation and redox changes. Toxicology 2006; 223: 235-247.
    • (2006) Toxicology , vol.223 , pp. 235-247
    • Jeng, J.H.1    Kuo, M.Y.2    Lee, P.H.3    Wang, Y.J.4    Lee, M.Y.5    Lee, J.J.6    Lin, B.R.7    Tai, T.F.8    Chang, M.C.9
  • 41
    • 33644873930 scopus 로고    scopus 로고
    • Histone deacetylase inhibitors reduce VEGF production and induce growth suppression and apoptosis in human mantle cell lymphoma
    • Heider U, Kaiser M, Sterz J, Zavrski I, Jakob C, Fleissner C, Eucker J, Possinger K, Sezer O: Histone deacetylase inhibitors reduce VEGF production and induce growth suppression and apoptosis in human mantle cell lymphoma. Eur J Haematol 2006; 76: 42-50.
    • (2006) Eur J Haematol , vol.76 , pp. 42-50
    • Heider, U.1    Kaiser, M.2    Sterz, J.3    Zavrski, I.4    Jakob, C.5    Fleissner, C.6    Eucker, J.7    Possinger, K.8    Sezer, O.9
  • 43
    • 79955579989 scopus 로고    scopus 로고
    • The microbiome and butyrate regulate energy metabolism and autophagy in the mammalian colon
    • Donohoe DR, Zhang X, Sun W, O'Connell TM, Bunger MK, Bultman SJ: The microbiome and butyrate regulate energy metabolism and autophagy in the mammalian colon. Cell Metab 2011; 13: 517-526.
    • (2011) Cell Metab , vol.13 , pp. 517-526
    • Donohoe, D.R.1    Zhang, X.2    Sun, W.3    O'Connell, T.M.4    Bunger, M.K.5    Bultman, S.J.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.