Dichloroacetate inhibits aerobic glycolysis in multiple myeloma cells and increases sensitivity to bortezomib

British Journal of Cancer

Volumn 108, Issue 8, 2013, Pages 1624-1633

  Sanchez, W Y ^a,d   McGee, S L ^b   Connor, T ^b   Mottram, B ^c   Wilkinson, A ^a   Whitehead, J P ^a   Vuckovic, S ^a,d,e   Catley, L ^a  

^a MATER MEDICAL RESEARCH INSTITUTE   (Australia)

^b DEAKIN UNIVERSITY   (Australia)

^c QUEENSLAND HEALTH   (Australia)

^d UNIVERSITY OF QUEENSLAND   (Australia)

^e QIMR BERGHOFER MEDICAL RESEARCH INSTITUTE   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

BORTEZOMIB; DICHLOROACETIC ACID; PHORBOL 13 ACETATE 12 MYRISTATE; PYRUVATE DEHYDROGENASE COMPLEX; SUPEROXIDE;

ANIMAL CELL; APOPTOSIS; ARTICLE; CANCER INHIBITION; CANCER SURVIVAL; CELL CYCLE G0 PHASE; CELL RESPIRATION; CONTROLLED STUDY; DRUG INHIBITION; DRUG SENSITIVITY; ENZYME ACTIVATION; G1 PHASE CELL CYCLE CHECKPOINT; G2 PHASE CELL CYCLE CHECKPOINT; GLYCOLYSIS; HUMAN; HUMAN CELL; MOUSE; MULTIPLE MYELOMA; MYELOMA CELL; NONHUMAN; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL;

AEROBIOSIS; ANIMALS; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; APOPTOSIS; BORONIC ACIDS; CELL GROWTH PROCESSES; CELL LINE, TUMOR; CHLOROACETATES; DRUG SYNERGISM; GLYCOLYSIS; HUMANS; MICE; MULTIPLE MYELOMA; OXYGEN CONSUMPTION; PYRAZINES; PYRUVATE DEHYDROGENASE COMPLEX; SUPEROXIDES;

EID: 84877045111     PISSN: 00070920     EISSN: 15321827     Source Type: Journal    
DOI: 10.1038/bjc.2013.120     Document Type: Article

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