Glycolytic enzyme upregulation and numbness of mitochondrial activity characterize the early phase of apoptosis in cerebellar granule cells

Apoptosis

Volumn 20, Issue 1, 2015, Pages 10-28

  Bobba, A ^a   Amadoro, G ^b   La Piana, G ^c   Calissano, P ^d   Atlante, A ^a  

^a CNR   (Italy)

^b INSTITUTE OF TRANSLATIONAL PHARMACOLOGY   (Italy)

^c UNIVERSITY OF BARI   (Italy)

^d EUROPEAN BRAIN RESEARCH INSTITUTE   (Italy)

Author keywords

Alzheimer; Apoptosis; Dichloroacetate; Glycolytic pathway; Mitochondria; Warburg

Indexed keywords

6 PHOSPHOFRUCTOKINASE; DICHLOROACETIC ACID; GLUCOSE; GLUCOSE TRANSPORTER; GLYCOLYTIC ENZYME; HEXOKINASE; PYRUVATE DEHYDROGENASE KINASE; OXYGEN;

ANAEROBIC GLYCOLYSIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; AROUSAL; ARTICLE; CEREBELLUM GRANULAR LAYER; CONTROLLED STUDY; GLUCOSE METABOLISM; GLYCOLYSIS; GRANULE CELL; MITOCHONDRION; NERVE DEGENERATION; NONHUMAN; OXYGEN CONSUMPTION; PHENOTYPE; PRIORITY JOURNAL; RAT; UPREGULATION; ANIMAL; CEREBELLUM; CYTOLOGY; DRUG EFFECTS; HIPPOCAMPUS; HUMAN; METABOLISM; NERVE CELL; PRIMARY CELL CULTURE; ULTRASTRUCTURE; WISTAR RAT;

ANIMALS; APOPTOSIS; CEREBELLUM; DICHLOROACETIC ACID; GLUCOSE TRANSPORT PROTEINS, FACILITATIVE; GLYCOLYSIS; HEXOKINASE; HIPPOCAMPUS; HUMANS; MITOCHONDRIA; NEURONS; OXYGEN; PHOSPHOFRUCTOKINASES; PRIMARY CELL CULTURE; RATS, WISTAR; UP-REGULATION;

EID: 84922004383     PISSN: 13608185     EISSN: 1573675X     Source Type: Journal    
DOI: 10.1007/s10495-014-1049-1     Document Type: Article

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