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Volumn 55, Issue 11, 2012, Pages 3051-3060

Acute exposure to resveratrol inhibits AMPK activity in human skeletal muscle cells

Author keywords

AICAR; AMPK; ERstress; Insulin resistance; Primary human myotubes; Resveratrol

Indexed keywords

ACETYL COENZYME A CARBOXYLASE; ACETYL COENZYME A CARBOXYLASE BETA; CCAAT ENHANCER BINDING PROTEIN; CCAAT ENHANCER BINDING PROTEIN HOMOLOGOUS PROTEIN; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; INITIATION FACTOR 2ALPHA; PALMITIC ACID; RESVERATROL; UNCLASSIFIED DRUG;

EID: 84867580794     PISSN: 0012186X     EISSN: 14320428     Source Type: Journal    
DOI: 10.1007/s00125-012-2691-1     Document Type: Article
Times cited : (39)

References (42)
  • 1
    • 79952451443 scopus 로고    scopus 로고
    • Obesity, insulin resistance and free fatty acids
    • Boden G (2011) Obesity, insulin resistance and free fatty acids. Curr Opin Endocrinol Diabetes Obes 18:139-143
    • (2011) Curr Opin Endocrinol Diabetes Obes , vol.18 , pp. 139-143
    • Boden, G.1
  • 2
    • 0026468362 scopus 로고
    • What if minkowski had been ageusic? An alternative angle on diabetes
    • McGarry JD (1992) What if Minkowski had been ageusic? An alternative angle on diabetes. Science 258:766-770
    • (1992) Science , vol.258 , pp. 766-770
    • McGarry, J.D.1
  • 3
    • 0000803875 scopus 로고
    • Plasma free fatty acid concentrations in obesity
    • Opie LH, Walfish PG (1963) Plasma free fatty acid concentrations in obesity. N Engl J Med 268:757-760
    • (1963) N Engl J Med , vol.268 , pp. 757-760
    • Opie, L.H.1    Walfish, P.G.2
  • 4
    • 0002697987 scopus 로고    scopus 로고
    • Cross-talk mechanisms in the development of insulin resistance of skeletal muscle cells. Palmitate rather than tumour necrosis factor inhibits insulin-dependent protein kinase B (PKB)/Akt stimulation and glucose uptake
    • Storz P, Doppler H, Wernig A, Pfizenmaier K, Muller G (1999) Cross-talk mechanisms in the development of insulin resistance of skeletal muscle cells. Palmitate rather than tumour necrosis factor inhibits insulin-dependent protein kinase B (PKB)/Akt stimulation and glucose uptake. Eur J Biochem 266:17-25
    • (1999) Eur J Biochem , vol.266 , pp. 17-25
    • Storz, P.1    Doppler, H.2    Wernig, A.3    Pfizenmaier, K.4    Muller, G.5
  • 5
    • 0142164965 scopus 로고    scopus 로고
    • Characterizing the effects of saturated fatty acids on insulin signaling and ceramide and diacylglycerol accumulation in 3T3-L1 adipocytes and C2C12 myotubes
    • Chavez JA, Summers SA (2003) Characterizing the effects of saturated fatty acids on insulin signaling and ceramide and diacylglycerol accumulation in 3T3-L1 adipocytes and C2C12 myotubes. Arch Biochem Biophys 419:101-109
    • (2003) Arch Biochem Biophys , vol.419 , pp. 101-109
    • Chavez, J.A.1    Summers, S.A.2
  • 6
    • 0038532298 scopus 로고    scopus 로고
    • A role for ceramide, but not diacylglycerol, in the antagonism of insulin signal transduction by saturated fatty acids
    • Chavez JA, Knotts TA, Wang LP et al (2003) A role for ceramide, but not diacylglycerol, in the antagonism of insulin signal transduction by saturated fatty acids. J Biol Chem 278:10297-10303
    • (2003) J Biol Chem , vol.278 , pp. 10297-10303
    • Chavez, J.A.1    Knotts, T.A.2    Wang, L.P.3
  • 7
    • 0031753812 scopus 로고    scopus 로고
    • Five-hour fatty acid elevation increases muscle lipids and impairs glycogen synthesis in the rat
    • Chalkley SM, Hettiarachchi M, Chisholm DJ, Kraegen EW (1998) Five-hour fatty acid elevation increases muscle lipids and impairs glycogen synthesis in the rat. Metabolism 47:1121-1126
    • (1998) Metabolism , vol.47 , pp. 1121-1126
    • Chalkley, S.M.1    Hettiarachchi, M.2    Chisholm, D.J.3    Kraegen, E.W.4
  • 9
    • 0036300538 scopus 로고    scopus 로고
    • Lipidinduced insulin resistance in human muscle is associated with changes in diacylglycerol, protein kinase C, and IkappaB-alpha
    • Itani SI, Ruderman NB, Schmieder F, Boden G (2002) Lipidinduced insulin resistance in human muscle is associated with changes in diacylglycerol, protein kinase C, and IkappaB-alpha. Diabetes 51:2005-2011
    • (2002) Diabetes , vol.51 , pp. 2005-2011
    • Itani, S.I.1    Ruderman, N.B.2    Schmieder, F.3    Boden, G.4
  • 10
    • 0033749620 scopus 로고    scopus 로고
    • Signalling aspects of insulin resistance in skeletal muscle: Mechanisms induced by lipid oversupply
    • Schmitz-Peiffer C (2000) Signalling aspects of insulin resistance in skeletal muscle: Mechanisms induced by lipid oversupply. Cell Signal 12:583-594
    • (2000) Cell Signal , vol.12 , pp. 583-594
    • Schmitz-Peiffer, C.1
  • 11
    • 43249083481 scopus 로고    scopus 로고
    • Free fatty acids and skeletal muscle insulin resistance
    • Kraegen EW, Cooney GJ (2008) Free fatty acids and skeletal muscle insulin resistance. Curr Opin Lipidol 19:235-241
    • (2008) Curr Opin Lipidol , vol.19 , pp. 235-241
    • Kraegen, E.W.1    Cooney, G.J.2
  • 12
    • 80455143206 scopus 로고    scopus 로고
    • Calorie restriction-like effects of 30 days of resveratrol supplementation on energy metabolism and metabolic profile in obese humans
    • Timmers S, Konings E, Bilet L et al (2011) Calorie restriction-like effects of 30 days of resveratrol supplementation on energy metabolism and metabolic profile in obese humans. Cell Metab 14:612-622
    • (2011) Cell Metab , vol.14 , pp. 612-622
    • Timmers, S.1    Konings, E.2    Bilet, L.3
  • 13
    • 77950348878 scopus 로고    scopus 로고
    • AMP-activated protein kinase-deficient mice are resistant to the metabolic effects of resveratrol
    • Um JH, Park SJ, Kang H et al (2010) AMP-activated protein kinase-deficient mice are resistant to the metabolic effects of resveratrol. Diabetes 59:554-563
    • (2010) Diabetes , vol.59 , pp. 554-563
    • Um, J.H.1    Park, S.J.2    Kang, H.3
  • 14
    • 33845399894 scopus 로고    scopus 로고
    • Resveratrol improves mitochondrial function and protects against metabolic disease by activating SIRT1 and PGC-1a
    • Lagouge M, Argmann C, Gerhart-Hines Z et al (2006) Resveratrol improves mitochondrial function and protects against metabolic disease by activating SIRT1 and PGC-1a. Cell 127:1109-1122
    • (2006) Cell , vol.127 , pp. 1109-1122
    • Lagouge, M.1    Argmann, C.2    Gerhart-Hines, Z.3
  • 15
    • 77249156847 scopus 로고    scopus 로고
    • Interdependence of AMPK and SIRT1 for metabolic adaptation to fasting and exercise in skeletal muscle
    • Canto C, Jiang LQ, Deshmukh AS et al (2010) Interdependence of AMPK and SIRT1 for metabolic adaptation to fasting and exercise in skeletal muscle. Cell Metab 11:213-219
    • (2010) Cell Metab , vol.11 , pp. 213-219
    • Canto, C.1    Jiang, L.Q.2    Deshmukh, A.S.3
  • 16
    • 65349177200 scopus 로고    scopus 로고
    • AMPK: An emerging drug target for diabetes and the metabolic syndrome
    • Zhang BB, Zhou G, Li C (2009) AMPK: An emerging drug target for diabetes and the metabolic syndrome. Cell Metab 9:407-416
    • (2009) Cell Metab , vol.9 , pp. 407-416
    • Zhang, B.B.1    Zhou, G.2    Li, C.3
  • 17
    • 40849092782 scopus 로고    scopus 로고
    • Adenosine 5'-monophosphate-activated protein kinase regulation of fatty acid oxidation in skeletal muscle
    • Osler ME, Zierath JR (2008) Adenosine 5'-monophosphate-activated protein kinase regulation of fatty acid oxidation in skeletal muscle. Endocrinology 149:935-941
    • (2008) Endocrinology , vol.149 , pp. 935-941
    • Osler, M.E.1    Zierath, J.R.2
  • 18
    • 58149152891 scopus 로고    scopus 로고
    • Globular adiponectin stimulates glucose transport in type 2 diabetic muscle
    • Kuoppamaa H, Skrobuk P, Sihvo M et al (2008) Globular adiponectin stimulates glucose transport in type 2 diabetic muscle. Diabetes Metab Res Rev 24:554-562
    • (2008) Diabetes Metab Res Rev , vol.24 , pp. 554-562
    • Kuoppamaa, H.1    Skrobuk, P.2    Sihvo, M.3
  • 19
    • 74049113270 scopus 로고    scopus 로고
    • Acute exposure to rosiglitazone does not affect glucose transport in intact human skeletal muscle
    • Skrobuk P, Kuoppamaa H, Hiukka A, Koistinen HA (2010) Acute exposure to rosiglitazone does not affect glucose transport in intact human skeletal muscle. Metabolism 59:224-230
    • (2010) Metabolism , vol.59 , pp. 224-230
    • Skrobuk, P.1    Kuoppamaa, H.2    Hiukka, A.3    Koistinen, H.A.4
  • 20
    • 0037494999 scopus 로고    scopus 로고
    • Insulin action in cultured human skeletal muscle cells during differentiation: Assessment of cell surface GLUT4 and GLUT1 content
    • Al-Khalili L, Chibalin AV, Kannisto K et al (2003) Insulin action in cultured human skeletal muscle cells during differentiation: Assessment of cell surface GLUT4 and GLUT1 content. Cell Mol Life Sci 60:991-998
    • (2003) Cell Mol Life Sci , vol.60 , pp. 991-998
    • Al-Khalili, L.1    Chibalin, A.V.2    Kannisto, K.3
  • 21
    • 0031906001 scopus 로고    scopus 로고
    • Stimulation of glucose and amino acid transport and activation of the insulin signaling pathways by insulin lispro in L6 skeletal muscle cells
    • Somwar R, Sweeney G, Ramlal T, Klip A (1998) Stimulation of glucose and amino acid transport and activation of the insulin signaling pathways by insulin lispro in L6 skeletal muscle cells. Clin Ther 20:125-140
    • (1998) Clin Ther , vol.20 , pp. 125-140
    • Somwar, R.1    Sweeney, G.2    Ramlal, T.3    Klip, A.4
  • 22
    • 70350506336 scopus 로고    scopus 로고
    • Evidence against a sexual dimorphism in glucose and fatty acid metabolism in skeletal muscle cultures from age-matched men and post-menopausal women
    • Rune A, Salehzadeh F, Szekeres F, Kuhn I, Osler ME, Al-Khalili L (2009) Evidence against a sexual dimorphism in glucose and fatty acid metabolism in skeletal muscle cultures from age-matched men and post-menopausal women. Acta Physiol (Oxf) 197:207-215
    • (2009) Acta Physiol (Oxf , vol.197 , pp. 207-215
    • Rune, A.1    Salehzadeh, F.2    Szekeres, F.3    Kuhn, I.4    Osler, M.E.5    Al-Khalili, L.6
  • 23
    • 0034773404 scopus 로고    scopus 로고
    • Role of AMP-activated protein kinase in mechanism of metformin action
    • Zhou G, Myers R, Li Yet al (2001) Role of AMP-activated protein kinase in mechanism of metformin action. J Clin Invest 108:1167-1174
    • (2001) J Clin Invest , vol.108 , pp. 1167-1174
    • Zhou, G.1    Myers, R.2    Li, Y.3
  • 24
    • 48249139503 scopus 로고    scopus 로고
    • Malonyl coenzymeA decarboxylase regulates lipid and glucose metabolism in human skeletal muscle
    • Bouzakri K, Austin R, Rune A et al (2008) Malonyl coenzymeA decarboxylase regulates lipid and glucose metabolism in human skeletal muscle. Diabetes 57:1508-1516
    • (2008) Diabetes , vol.57 , pp. 1508-1516
    • Bouzakri, K.1    Austin, R.2    Rune, A.3
  • 25
    • 17844400342 scopus 로고    scopus 로고
    • 5'AMP activated protein kinase expression in human skeletal muscle: Effects of strength training and type 2 diabetes
    • Wojtaszewski JF, Birk JB, Frosig C, Holten M, Pilegaard H, Dela F (2005) 5'AMP activated protein kinase expression in human skeletal muscle: Effects of strength training and type 2 diabetes. J Physiol 564:563-573
    • (2005) J Physiol , vol.564 , pp. 563-573
    • Wojtaszewski, J.F.1    Birk, J.B.2    Frosig, C.3    Holten, M.4    Pilegaard, H.5    Dela, F.6
  • 26
    • 34250899722 scopus 로고    scopus 로고
    • Signal integration in the endoplasmic reticulum unfolded protein response
    • Ron D, Walter P (2007) Signal integration in the endoplasmic reticulum unfolded protein response. Nat Rev Mol Cell Biol 8:519-529
    • (2007) Nat Rev Mol Cell Biol , vol.8 , pp. 519-529
    • Ron, D.1    Walter, P.2
  • 27
    • 39149104320 scopus 로고    scopus 로고
    • The role for endoplasmic reticulum stress in diabetes mellitus
    • Eizirik DL, Cardozo AK, Cnop M (2008) The role for endoplasmic reticulum stress in diabetes mellitus. Endocr Rev 29:42-61
    • (2008) Endocr Rev , vol.29 , pp. 42-61
    • Eizirik, D.L.1    Cardozo, A.K.2    Cnop, M.3
  • 28
    • 33751072349 scopus 로고    scopus 로고
    • Resveratrol improves health and survival of mice on a high-calorie diet
    • Baur JA, Pearson KJ, Price NL et al (2006) Resveratrol improves health and survival of mice on a high-calorie diet. Nature 444:337-342
    • (2006) Nature , vol.444 , pp. 337-342
    • Baur, J.A.1    Pearson, K.J.2    Price, N.L.3
  • 29
    • 33744946526 scopus 로고    scopus 로고
    • Resveratrol, a red wine antioxidant, possesses an insulin-like effect in streptozotocininduced diabetic rats
    • Su HC, Hung LM, Chen JK (2006) Resveratrol, a red wine antioxidant, possesses an insulin-like effect in streptozotocininduced diabetic rats. Am J Physiol Endocrinol Metab 290: E1339-E1346
    • (2006) Am J Physiol Endocrinol Metab , vol.290
    • Su, H.C.1    Hung, L.M.2    Chen, J.K.3
  • 30
    • 34548857700 scopus 로고    scopus 로고
    • SIRT1 improves insulin sensitivity under insulin-resistant conditions by repressing PTP1B
    • Sun C, Zhang F, Ge X et al (2007) SIRT1 improves insulin sensitivity under insulin-resistant conditions by repressing PTP1B. Cell Metab 6:307-319
    • (2007) Cell Metab , vol.6 , pp. 307-319
    • Sun, C.1    Zhang, F.2    Ge, X.3
  • 31
    • 33749349202 scopus 로고    scopus 로고
    • Polyphenols stimulate AMP-activated protein kinase, lower lipids, and inhibit accelerated atherosclerosis in diabetic LDL receptor-deficient mice
    • Zang M, Xu S, Maitland-Toolan KA et al (2006) Polyphenols stimulate AMP-activated protein kinase, lower lipids, and inhibit accelerated atherosclerosis in diabetic LDL receptor-deficient mice. Diabetes 55:2180-2191
    • (2006) Diabetes , vol.55 , pp. 2180-2191
    • Zang, M.1    Xu, S.2    Maitland-Toolan, K.A.3
  • 32
    • 0019762341 scopus 로고
    • The effect of insulin on the disposal of intravenous glucose. Results from indirect calorimetry and hepatic and femoral venous catheterization
    • DeFronzo RA, Jacot E, Jequier E, Maeder E, Wahren J, Felber JP (1981) The effect of insulin on the disposal of intravenous glucose. Results from indirect calorimetry and hepatic and femoral venous catheterization. Diabetes 30:1000-1007
    • (1981) Diabetes , vol.30 , pp. 1000-1007
    • DeFronzo, R.A.1    Jacot, E.2    Jequier, E.3    Maeder, E.4    Wahren, J.5    Felber, J.P.6
  • 33
    • 0021994683 scopus 로고
    • Effects of insulin on peripheral and splanchnic glucose metabolism in noninsulin-dependent (type II) diabetes mellitus
    • DeFronzo RA, Gunnarsson R, Bjorkman O, Olsson M, Wahren J (1985) Effects of insulin on peripheral and splanchnic glucose metabolism in noninsulin-dependent (type II) diabetes mellitus. J Clin Invest 76:149-155
    • (1985) J Clin Invest , vol.76 , pp. 149-155
    • DeFronzo, R.A.1    Gunnarsson, R.2    Bjorkman, O.3    Olsson, M.4    Wahren, J.5
  • 34
    • 47749148061 scopus 로고    scopus 로고
    • Stimulation of muscle cell glucose uptake by resveratrol through sirtuins and AMPK
    • Breen DM, Sanli T, Giacca A, Tsiani E (2008) Stimulation of muscle cell glucose uptake by resveratrol through sirtuins and AMPK. Biochem Biophys Res Commun 374:117-122
    • (2008) Biochem Biophys Res Commun , vol.374 , pp. 117-122
    • Breen, D.M.1    Sanli, T.2    Giacca, A.3    Tsiani, E.4
  • 35
    • 79955441995 scopus 로고    scopus 로고
    • Hypoglycemic effect of resveratrol in type 2 diabetic model db/db mice and its actions in cultured L6 myotubes and RIN-5F pancreatic ß-cells
    • Minakawa M, Kawano A, Miura Y, Yagasaki K (2011) Hypoglycemic effect of resveratrol in type 2 diabetic model db/db mice and its actions in cultured L6 myotubes and RIN-5F pancreatic ß-cells. J Clin Biochem Nutr 48:237-244
    • (2011) J Clin Biochem Nutr , vol.48 , pp. 237-244
    • Minakawa, M.1    Kawano, A.2    Miura, Y.3    Yagasaki, K.4
  • 36
    • 79251486187 scopus 로고    scopus 로고
    • Nutritional modulation of training-induced skeletal muscle adaptations
    • Hawley JA, Burke LM, Phillips SM, Spriet LL (2011) Nutritional modulation of training-induced skeletal muscle adaptations. J Appl Physiol 110:834-845
    • (2011) J Appl Physiol , vol.110 , pp. 834-845
    • Hawley, J.A.1    Burke, L.M.2    Phillips, S.M.3    Spriet, L.L.4
  • 37
    • 34548730196 scopus 로고    scopus 로고
    • Resveratrol is a class IA phosphoinositide 3-kinase inhibitor
    • Fröjdö S, Cozzone D, Vidal H, Pirola L (2007) Resveratrol is a class IA phosphoinositide 3-kinase inhibitor. Biochem J 406:511-518
    • (2007) Biochem J , vol.406 , pp. 511-518
    • Fröjdö, S.1    Cozzone, D.2    Vidal, H.3    Pirola, L.4
  • 38
    • 33746862126 scopus 로고    scopus 로고
    • Resveratrol inhibits insulin responses in a SirT1-independent pathway
    • Zhang J (2006) Resveratrol inhibits insulin responses in a SirT1-independent pathway. Biochem J 397:519-527
    • (2006) Biochem J , vol.397 , pp. 519-527
    • Zhang, J.1
  • 39
    • 79951726016 scopus 로고    scopus 로고
    • Phosphoinositide 3-kinase as a novel functional target for the regulation of the insulin signaling pathway by SIRT1
    • Fröjdö S, Durand C, Molin L et al (2011) Phosphoinositide 3-kinase as a novel functional target for the regulation of the insulin signaling pathway by SIRT1. Mol Cell Endocrinol 335:166-176
    • (2011) Mol Cell Endocrinol , vol.335 , pp. 166-176
    • Fröjdö, S.1    Durand, C.2    Molin, L.3
  • 40
    • 0035089064 scopus 로고    scopus 로고
    • Inhibition of glucose and dehydroascorbic acid uptakes by resveratrol in human transformed myelocytic cells
    • Park JB (2001) Inhibition of glucose and dehydroascorbic acid uptakes by resveratrol in human transformed myelocytic cells. J Nat Prod 64:381-384
    • (2001) J Nat Prod , vol.64 , pp. 381-384
    • Park, J.B.1
  • 41
    • 84863011114 scopus 로고    scopus 로고
    • Resveratrol ameliorates aging-related metabolic phenotypes by inhibiting cAMP phosphodiesterases
    • Park S-J, Ahmad F, Philp A et al (2012) Resveratrol ameliorates aging-related metabolic phenotypes by inhibiting cAMP phosphodiesterases. Cell 148:421-433
    • (2012) Cell , vol.148 , pp. 421-433
    • Park, S.-J.1    Ahmad, F.2    Philp, A.3
  • 42
    • 77953291946 scopus 로고    scopus 로고
    • Ascofuranone prevents ER stress-induced insulin resistance via activation of AMP-activated protein kinase in L6 myotube cells
    • Hwang S-L, Chang H-W, Lee I-K, Yang B-K, Magae J, Chang Y-C (2010) Ascofuranone prevents ER stress-induced insulin resistance via activation of AMP-activated protein kinase in L6 myotube cells. Biochem Biophys Res Commun 396:967-972
    • (2010) Biochem Biophys Res Commun , vol.396 , pp. 967-972
    • Hwang, S.-L.1    Chang, H.-W.2    Lee, I.-K.3    Yang, B.-K.4    Magae, J.5    Chang, Y.-C.6


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