Mitochondrial protection by the mixed muscarinic/σ1 ligand ANAVEX2-73, a tetrahydrofuran derivative, in Aβ25–35 peptide-injected mice, a nontransgenic Alzheimer’s disease model

Frontiers in Cellular Neuroscience

Volumn 8, Issue JAN, 2015, Pages 1-11

  Lahmy, Valentine ^a,b   Long, Romain ^c,d   Morin, Didier ^c,d   Villard, Vanessa ^b   Maurice, Tangui ^a,b  

^a University of Montpellier   (France)

^b AMYLGEN   (France)

^c INSERM U955   (France)

^d UNIVERSITÉ PARIS EST CRÉTEIL   (France)

Author keywords

Alzheimer s disease; ANAVEX2 73; Cytoprotection; Mitochondrial damages; Sigma 1 receptor

Indexed keywords

AMYLOID BETA PROTEIN [25-35]; ANAVEX 2 73; CYTOCHROME C; CYTOCHROME C OXIDASE; MUSCARINIC RECEPTOR; PROTEIN BAX; PROTEIN BCL 2; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE (UBIQUINONE); SIGMA 1 OPIATE RECEPTOR; SUCCINATE DEHYDROGENASE; UBIQUINOL CYTOCHROME C REDUCTASE; UNCLASSIFIED DRUG;

ALZHEIMER DISEASE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BREATHING RATE; CONTROLLED STUDY; DRUG ACTIVITY; DRUG EFFECT; HIPPOCAMPUS; LIPID PEROXIDATION; MALE; MITOCHONDRIAL RESPIRATION; MITOCHONDRION; MOUSE; NEUROPROTECTION; NONHUMAN; OXIDATIVE STRESS; OXYGEN CONSUMPTION; PROTEIN EXPRESSION; RESPIRATORY FAILURE; WESTERN BLOTTING;

EID: 84921849377     PISSN: 16625102     EISSN: None     Source Type: Journal    
DOI: 10.3389/fncel.2014.00463     Document Type: Article

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