Astragalin inhibits IL-1β-induced inflammatory mediators production in human osteoarthritis chondrocyte by inhibiting NF-κB and MAPK activation

International Immunopharmacology

Volumn 25, Issue 1, 2015, Pages 83-87

  Ma, Zhiqiang ^a   Piao, Taikui ^b   Wang, Yanlong ^a   Liu, Jianyu ^a  

^a HARBIN MEDICAL UNIVERSITY   (China)

^b Harbin Children's Hospital 150020   (China)

Author keywords

Astragalin; IL 1 ; NF B; Osteoarthritis

Indexed keywords

2 CHLORO 5 NITROBENZANILIDE; ASTRAGALIN; CYCLOOXYGENASE 2; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 1BETA; MITOGEN ACTIVATED PROTEIN KINASE; NITRIC OXIDE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PROSTAGLANDIN E2; 2-CHLORO-5-NITROBENZANILIDE; ANILIDE; ANTIINFLAMMATORY AGENT; KAEMPFEROL DERIVATIVE; NOS2 PROTEIN, HUMAN;

ADULT; ANTIINFLAMMATORY ACTIVITY; ARTICLE; ARTICULAR CARTILAGE; CARTILAGE CELL; CELL VIABILITY; CYTOTOXICITY; DRUG EFFECT; DRUG MECHANISM; DRUG POTENCY; ENZYME ACTIVATION; ENZYME INHIBITION; ENZYME LINKED IMMUNOSORBENT ASSAY; HUMAN; HUMAN CELL; MEDIATOR; MIDDLE AGED; OSTEOARTHRITIS; PRIORITY JOURNAL; WESTERN BLOTTING; AGED; ANTAGONISTS AND INHIBITORS; CELL CULTURE; DRUG EFFECTS; GENETICS; IMMUNOLOGY; METABOLISM; ROSE; TRANSCRIPTION INITIATION;

ADULT; AGED; ANILIDES; ANTI-INFLAMMATORY AGENTS; CELLS, CULTURED; CHONDROCYTES; CYCLOOXYGENASE 2; DINOPROSTONE; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; HUMANS; INTERLEUKIN-1BETA; KAEMPFEROLS; MIDDLE AGED; NF-KAPPA B; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE II; OSTEOARTHRITIS; PPAR GAMMA; ROSA; TRANSCRIPTIONAL ACTIVATION;

EID: 84921712372     PISSN: 15675769     EISSN: 18781705     Source Type: Journal    
DOI: 10.1016/j.intimp.2015.01.018     Document Type: Article

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