Astragalin inhibits airway eotaxin-1 induction and epithelial apoptosis through modulating oxidative stress-responsive MAPK signaling

BMC Pulmonary Medicine

Volumn 14, Issue 1, 2014, Pages

  Cho, In Hee ^a   Gong, Ju Hyun ^a   Kang, Min Kyung ^a   Lee, Eun Jung ^a   Park, Jung Han Y ^a   Park, Sang Jae ^b   Kang, Young Hee ^a  

^a Hallym University   (South Korea)

^b Biotopia Co   (South Korea)

Author keywords

Airway apoptosis; Asthma; Astragalin; Eotaxin 1; Oxidative stress

Indexed keywords

APOPTOSIS INHIBITOR; ASTRAGALIN; CASPASE 3; ENDOTOXIN; EOTAXIN; HYDROGEN PEROXIDE; LIPOPOLYSACCHARIDE; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; NADPH OXIDASE SUBUNIT P22; NADPH OXIDASE SUBUNIT P47; PHOSPHOLIPASE C GAMMA1; PROTEIN INHIBITOR; PROTEIN KINASE B; PROTEIN KINASE C BETA; PROTEIN KINASE C BETA2; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; STRESS ACTIVATED PROTEIN KINASE; TOLL LIKE RECEPTOR 4; UNCLASSIFIED DRUG; PROTEIN KINASE C BETA 2; PROTEIN P22; TOLL LIKE RECEPTOR 2; CCL11 PROTEIN, HUMAN; KAEMPFEROL DERIVATIVE; MITOGEN ACTIVATED PROTEIN KINASE KINASE; OXIDIZING AGENT; PHOSPHOLIPASE C GAMMA; PLANT MEDICINAL PRODUCT; TLR4 PROTEIN, HUMAN;

APOPTOSIS; ARTICLE; BRONCHUS MUCOSA; CELL VIABILITY; CHEMICAL STRUCTURE; CONTROLLED STUDY; DENSITOMETER; DRUG CYTOTOXICITY; ENZYME ACTIVATION; ENZYME INDUCTION; ENZYME PHOSPHORYLATION; EOSINOPHILIA; FLUORESCENCE MICROSCOPY; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; IMMUNOCYTOCHEMISTRY; LUNG ALVEOLUS EPITHELIUM; MTT ASSAY; OXIDATIVE STRESS; PROTEIN EXPRESSION; PROTEIN INDUCTION; RESPIRATORY EPITHELIUM; SIGNAL TRANSDUCTION; UPREGULATION; WESTERN BLOTTING; ASTHMA; DISEASE PREDISPOSITION; EPITHELIUM CELL; IN VITRO STUDY; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; ANTAGONISTS AND INHIBITORS; BRONCHUS; CELL CULTURE; DIOSPYROS; DRUG EFFECTS; EOSINOPHIL; METABOLISM; PHOSPHORYLATION; PLANT LEAF;

APOPTOSIS; BRONCHI; CASPASE 3; CELLS, CULTURED; CHEMOKINE CCL11; DIOSPYROS; ENZYME ACTIVATION; EOSINOPHILS; EPITHELIAL CELLS; HUMANS; HYDROGEN PEROXIDE; JNK MITOGEN-ACTIVATED PROTEIN KINASES; KAEMPFEROLS; LIPOPOLYSACCHARIDES; MAP KINASE SIGNALING SYSTEM; MITOGEN-ACTIVATED PROTEIN KINASE KINASES; NADPH OXIDASE; OXIDANTS; OXIDATIVE STRESS; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHOLIPASE C GAMMA; PHOSPHORYLATION; PLANT LEAVES; PLANT PREPARATIONS; PROTEIN KINASE C BETA; PROTO-ONCOGENE PROTEINS C-AKT; REACTIVE OXYGEN SPECIES; TOLL-LIKE RECEPTOR 4;

EID: 84904774748     PISSN: None     EISSN: 14712466     Source Type: Journal    
DOI: 10.1186/1471-2466-14-122     Document Type: Article

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