Anti-inflammatory effects of 5-HT3 receptor antagonists in interleukin-1beta stimulated primary human chondrocytes

International Immunopharmacology

Volumn 22, Issue 1, 2014, Pages 160-166

  Stratz, Christian ^a   Anakwue, John ^b   Bhatia, Harsharan ^b   Pitz, Stefanie ^b   Fiebich, Bernd L ^b,c  

^a UNIVERSITY HEART CENTER FREIBURG BAD KROZINGEN   (Germany)

^b UNIVERSITY OF FREIBURG   (Germany)

^c VIVACELL BIOTECHNOLOGY GMBH   (Germany)

Author keywords

Chondrocytes; Cyclooxygenase; Cytokines; Serotonin; Tropisetron

Indexed keywords

8 ISOPROSTANE; ARACHIDONIC ACID; CYCLOOXYGENASE 2; DOLASETRON MESILATE; GRANISETRON; INTERLEUKIN 6; ISOPROSTANE DERIVATIVE; MICROSOME ENZYME; PROSTAGLANDIN E SYNTHASE 1; PROSTAGLANDIN E2; RECOMBINANT INTERLEUKIN 1BETA; TROPISETRON; 8-EPI-PROSTAGLANDIN F2ALPHA; INDOLE DERIVATIVE; INTERLEUKIN 1BETA; ISOMERASE; PROSTAGLANDIN E SYNTHASE; PROSTAGLANDIN F2 ALPHA; QUINOLIZINE DERIVATIVE; SEROTONIN 3 ANTAGONIST; SEROTONIN 3 RECEPTOR;

ANTIINFLAMMATORY ACTIVITY; ARTICLE; CARTILAGE CELL; CELL STIMULATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; DRUG MECHANISM; ENZYME ACTIVITY; ENZYME IMMUNOASSAY; ENZYME LINKED IMMUNOSORBENT ASSAY; HUMAN; HUMAN CELL; IMMUNOSTIMULATION; PRIMARY CELL; PRIORITY JOURNAL; WESTERN BLOTTING; ANALOGS AND DERIVATIVES; ARTHRITIS, RHEUMATOID; CELL CULTURE; DRUG EFFECTS; IMMUNOLOGY; METABOLISM; PRIMARY CELL CULTURE;

ARTHRITIS, RHEUMATOID; CELLS, CULTURED; CHONDROCYTES; CYCLOOXYGENASE 2; DINOPROST; DINOPROSTONE; HUMANS; INDOLES; INTERLEUKIN-1BETA; INTERLEUKIN-6; INTRAMOLECULAR OXIDOREDUCTASES; PRIMARY CELL CULTURE; QUINOLIZINES; RECEPTORS, SEROTONIN, 5-HT3; SEROTONIN 5-HT3 RECEPTOR ANTAGONISTS;

EID: 84904014767     PISSN: 15675769     EISSN: 18781705     Source Type: Journal    
DOI: 10.1016/j.intimp.2014.06.003     Document Type: Article

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