The importance of ligands for G protein-coupled receptor stability

Trends in Biochemical Sciences

Volumn 40, Issue 2, 2015, Pages 79-87

  Zhang, Xianjun ^a   Stevens, Raymond C ^a   Xu, Fei ^a  

^a SHANGHAITECH UNIVERSITY   (China)

Author keywords

GPCR stabilization; Ligand residence time; Receptor residence time

Indexed keywords

G PROTEIN COUPLED RECEPTOR; LIGAND; PROTEIN BINDING;

BINDING AFFINITY; BINDING SITE; CRYSTALLIZATION; GLYCOSYLATION; HUMAN; LIGAND BINDING; MOLECULAR DYNAMICS; MOLECULAR RECOGNITION; PALMITOYLATION; PROTEIN ANALYSIS; PROTEIN CONFORMATION; PROTEIN DOMAIN; PROTEIN FOLDING; PROTEIN PROTEIN INTERACTION; PROTEIN STABILITY; REVIEW; THERMOSTABILITY; CELL MEMBRANE; CHEMISTRY; KINETICS; METABOLISM; STRUCTURE ACTIVITY RELATION;

CELL MEMBRANE; KINETICS; LIGANDS; PROTEIN BINDING; RECEPTORS, G-PROTEIN-COUPLED; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84921559394     PISSN: 09680004     EISSN: 13624326     Source Type: Journal    
DOI: 10.1016/j.tibs.2014.12.005     Document Type: Review

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