메뉴 건너뛰기




Volumn 56, Issue 5, 2001, Pages 441-451

Paradoxical trafficking and regulation of 5-HT2A receptors by agonists and antagonists

Author keywords

Antidepressant; Antipsychotic; Arrestin; Clozapine; Down regulation; Internalization

Indexed keywords

2 CHLORO 11 (3 DIMETHYLAMINOPROPYLIDENE)MORPHANTHRIDINE; 2,3,3A,12B TETRAHYDRO 3 METHYL 1H DIBENZO[B,F]OXEPINO[10,11 C]PYRROLE; 4 IODO 2,5 DIMETHOXYAMPHETAMINE; AMFEBUTAMONE; AMITRIPTYLINE; AMOXAPINE; ANTIDEPRESSANT AGENT; CHLORPROMAZINE; CITALOPRAM; CLOMIPRAMINE; CLOZAPINE; DESIPRAMINE; DOSULEPIN; FLUOXETINE; GUANINE NUCLEOTIDE BINDING PROTEIN; HALOPERIDOL; IMIPRAMINE; IPRINDOLE; KETANSERIN; LOXAPINE; LYSERGIDE; MIANSERIN; MOPERONE; NEFAZODONE; NEUROLEPTIC AGENT; PARGYLINE; PAROXETINE; PHENELZINE; QUIPAZINE; RISPERIDONE; SEROTONIN 2A RECEPTOR; SPIPERONE; TRANYLCYPROMINE; UNINDEXED DRUG; ZIMELDINE;

EID: 0035891883     PISSN: 03619230     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0361-9230(01)00623-2     Document Type: Conference Paper
Times cited : (258)

References (108)
  • 1
    • 0027537778 scopus 로고
    • Paradoxical increase of 5-hydroxytryptamine2 receptors and 5-hydroxytryptamine2 receptor mRNA in cerebellar granule cells after persistent 5-hydroxytryptamine2 receptor stimulation
    • (1993) Mol. Pharmacol. , vol.43 , pp. 349-355
    • Akiyoshi, J.1    Hough, C.2    Chuang, D.M.3
  • 16
    • 0029619094 scopus 로고
    • Role of second messengers in agonist up-regulation of 5-HT2A (5-HT2) receptor binding sites in cerebellar granule neurons: Involvement of calcium influx and a calmodulin-dependent pathway
    • (1995) J. Pharmacol. Exp. Ther. , vol.275 , pp. 674-680
    • Chen, H.1    Li, H.2    Chuang, D.M.3
  • 21
    • 0023871404 scopus 로고
    • Effects of chronic oral administration of the antidepressants, desmethylimipramine and zimelidine on rat cortical GABAB binding sites: A comparison with 5-HT2 binding site changes
    • (1988) Br. J. Pharmacol. , vol.93 , pp. 331-336
    • Cross, J.A.1    Horton, R.W.2
  • 23
    • 0021894160 scopus 로고
    • Decreased 5-HT2 but not 5-HT1 receptor binding in cortex of rat after chronic administration of dothiepin. Application of the Woolf plot to analysis of binding parameters
    • (1985) Neuropharmacology , vol.24 , pp. 275-278
    • Diggory, G.L.1    Buckett, W.R.2
  • 29
    • 0021074927 scopus 로고
    • Bupropion: A new antidepressant drug; the mechanism of action of which is not associated with down-regulation of postsynaptic beta-adrenergic, serotonergic (5-HT2), alpha 2-adrenergic, imipramine and dopaminergic receptors in brain
    • (1983) Neuropharmacology , vol.22 , pp. 1257-1267
    • Ferris, R.M.1    Beaman, O.J.2
  • 40
    • 0028176097 scopus 로고
    • 5-Hydroxytryptamine2 and beta-adrenergic receptor regulation in rat brain following chronic treatment with desipramine and fluoxetine alone and in combination
    • (1994) J. Neurochem. , vol.62 , pp. 2262-2268
    • Goodnough, D.B.1    Baker, G.B.2
  • 41
    • 0028182725 scopus 로고
    • Comparisons of the actions of high and low doses of the MAO inhibitor tranylcypromine on 5-HT2 binding sites in rat cortex
    • (1994) J. Neural Transm. , vol.41 , Issue.SUPPL. , pp. 127-134
    • Goodnough, D.B.1    Baker, G.B.2
  • 56
  • 61
    • 0021272516 scopus 로고
    • Down-regulation of opiate receptor in neuroblastoma x glioma NG108-15 hybrid cells. Chloroquine promotes accumulation of tritiated enkephalin in the lysosomes
    • (1984) J. Biol. Chem. , vol.259 , pp. 4096-4104
    • Law, P.Y.1    Hom, D.S.2    Loh, H.H.3
  • 69
  • 75
    • 0025667832 scopus 로고
    • Rapid desensitization and resensitization of 5-HT2 receptor mediated phosphatidyl inositol hydrolysis by serotonin agonists in quiescent calf aortic smooth muscle cells
    • (1990) Life Sci. , vol.47 , pp. 2009-2019
    • Pauwels, P.J.1    Van Gompel, P.2    Leysen, J.E.3
  • 76
  • 79
  • 93
    • 0018911415 scopus 로고
    • Decrease in [3H]-serotonin binding in rat brain produced by the repeated administration of either monoamine oxidase inhibitors or centrally acting serotonin agonists
    • (1980) Neuropharmacology , vol.19 , pp. 1063-1070
    • Savage, D.D.1    Mendels, J.2    Frazer, A.3
  • 96
    • 0022924324 scopus 로고
    • Down-regulation of serotonin2, but not of beta-adrenergic receptors during chronic treatment with amitryptiline is independent of stimulation of serotonin2 and beta-adrenergic receptors
    • (1986) Neuropharmacology , vol.25 , pp. 1301-1306
    • Scott, J.A.1    Crews, F.T.2
  • 99
    • 0027413354 scopus 로고
    • Selective down-regulation of the agonist-dependent high affinity state of rat cortical 5-HT2 receptors following chronic treatment with amperozide
    • (1993) J. Recept. Res. , vol.13 , pp. 379-392
    • Svartengren, J.O.1
  • 102
    • 0028235547 scopus 로고
    • Antagonist-mediated down-regulation of 5-hydroxytryptamine type 2 receptor gene expression: Modulation of transcription
    • (1994) Mol. Pharmacol. , vol.45 , pp. 1095-1100
    • Toth, M.1    Shenk, T.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.