-
1
-
-
84876784070
-
High-level semi-synthetic production of the potent antimalarial artemisinin
-
Paddon C.J., Westfall P.J., Pitera D.J., Benjamin K., Fisher K., McPhee D., Leavell M.D., Tai A., Main A., Eng D., et al. High-level semi-synthetic production of the potent antimalarial artemisinin. Nature 2013, 496:528-532.
-
(2013)
Nature
, vol.496
, pp. 528-532
-
-
Paddon, C.J.1
Westfall, P.J.2
Pitera, D.J.3
Benjamin, K.4
Fisher, K.5
McPhee, D.6
Leavell, M.D.7
Tai, A.8
Main, A.9
Eng, D.10
-
2
-
-
84910056833
-
Reconstitution of a 10-gene pathway for synthesis of the plant alkaloid dihydrosanguinarine in Saccharomyces cerevisiae
-
Fossati E., Ekins A., Narcross L., Zhu Y., Falgueyret J.-P., Beaudoin G.A.W., Facchini P.J., Martin V.J.J. Reconstitution of a 10-gene pathway for synthesis of the plant alkaloid dihydrosanguinarine in Saccharomyces cerevisiae. Nat Commun 2014, 5:3283.
-
(2014)
Nat Commun
, vol.5
, pp. 3283
-
-
Fossati, E.1
Ekins, A.2
Narcross, L.3
Zhu, Y.4
Falgueyret, J.-P.5
Beaudoin, G.A.W.6
Facchini, P.J.7
Martin, V.J.J.8
-
3
-
-
79958715193
-
Optimization of a heterologous pathway for the production of flavonoids from glucose
-
Santos C.N.S., Koffas M., Stephanopoulos G. Optimization of a heterologous pathway for the production of flavonoids from glucose. Metab Eng 2011, 13:392-400.
-
(2011)
Metab Eng
, vol.13
, pp. 392-400
-
-
Santos, C.N.S.1
Koffas, M.2
Stephanopoulos, G.3
-
4
-
-
38049001166
-
Non-fermentative pathways for synthesis of branched-chain higher alcohols as biofuels
-
Atsumi S., Hanai T., Liao J.C. Non-fermentative pathways for synthesis of branched-chain higher alcohols as biofuels. Nature 2008, 451:86-89.
-
(2008)
Nature
, vol.451
, pp. 86-89
-
-
Atsumi, S.1
Hanai, T.2
Liao, J.C.3
-
5
-
-
0142027026
-
Metabolic engineering for the microbial production of 1,3-propanediol
-
Nakamura C.E., Whited G.M. Metabolic engineering for the microbial production of 1,3-propanediol. Curr Opin Biotechnol 2003, 14:454-459.
-
(2003)
Curr Opin Biotechnol
, vol.14
, pp. 454-459
-
-
Nakamura, C.E.1
Whited, G.M.2
-
6
-
-
33747280991
-
Production of succinic acid by bacterial fermentation
-
Song H., Lee S.Y. Production of succinic acid by bacterial fermentation. Enzyme Microb Technol 2006, 39:352-361.
-
(2006)
Enzyme Microb Technol
, vol.39
, pp. 352-361
-
-
Song, H.1
Lee, S.Y.2
-
7
-
-
79959374585
-
Metabolic engineering of Escherichia coli for direct production of 1,4-butanediol
-
Yim H., Haselbeck R., Niu W., Pujol-Baxley C., Burgard A., Boldt J., Khandurina J., Trawick J.D., Osterhout R.E., Stephen R., et al. Metabolic engineering of Escherichia coli for direct production of 1,4-butanediol. Nat Chem Biol 2011, 7:445-452.
-
(2011)
Nat Chem Biol
, vol.7
, pp. 445-452
-
-
Yim, H.1
Haselbeck, R.2
Niu, W.3
Pujol-Baxley, C.4
Burgard, A.5
Boldt, J.6
Khandurina, J.7
Trawick, J.D.8
Osterhout, R.E.9
Stephen, R.10
-
8
-
-
70349964350
-
Automated design of synthetic ribosome binding sites to control protein expression
-
Salis H., Mirsky E., Voigt C. Automated design of synthetic ribosome binding sites to control protein expression. Nat Biotechnol 2009, 27.
-
(2009)
Nat Biotechnol
, pp. 27
-
-
Salis, H.1
Mirsky, E.2
Voigt, C.3
-
9
-
-
67349270900
-
Enzymatic assembly of DNA molecules up to several hundred kilobases
-
Gibson D.G., Young L., Chuang R.-Y., Venter J.C., Hutchison C.A., Smith H.O. Enzymatic assembly of DNA molecules up to several hundred kilobases. Nat Methods 2009, 6:343-345.
-
(2009)
Nat Methods
, vol.6
, pp. 343-345
-
-
Gibson, D.G.1
Young, L.2
Chuang, R.-Y.3
Venter, J.C.4
Hutchison, C.A.5
Smith, H.O.6
-
10
-
-
56649114274
-
A one pot, one step, precision cloning method with high throughput capability
-
Engler C., Kandzia R., Marillonnet S. A one pot, one step, precision cloning method with high throughput capability. PLoS One 2008, 3:e3647.
-
(2008)
PLoS One
, vol.3
, pp. e3647
-
-
Engler, C.1
Kandzia, R.2
Marillonnet, S.3
-
11
-
-
84896836282
-
Rapid and reliable DNA assembly via ligase cycling reaction
-
Kok S., Stanton L., Slaby T. Rapid and reliable DNA assembly via ligase cycling reaction. ACS Synth Biol 2014, 3:97-106.
-
(2014)
ACS Synth Biol
, vol.3
, pp. 97-106
-
-
Kok, S.1
Stanton, L.2
Slaby, T.3
-
12
-
-
65549123112
-
Pyruvate kinase-deficient Escherichia coli exhibits increased plasmid copy number and cyclic AMP levels
-
Cunningham D.S., Liu Z., Domagalski N., Koepsel R.R., Ataai M.M., Domach M.M. Pyruvate kinase-deficient Escherichia coli exhibits increased plasmid copy number and cyclic AMP levels. J Bacteriol 2009, 191:3041-3049.
-
(2009)
J Bacteriol
, vol.191
, pp. 3041-3049
-
-
Cunningham, D.S.1
Liu, Z.2
Domagalski, N.3
Koepsel, R.R.4
Ataai, M.M.5
Domach, M.M.6
-
13
-
-
84890395226
-
Expression-level optimization of a multi-enzyme pathway in the absence of a high-throughput assay
-
Lee M., Aswani A., Han A., Tomlin C.J., Dueber J.E. Expression-level optimization of a multi-enzyme pathway in the absence of a high-throughput assay. Nucleic Acids Res 2013, 10.
-
(2013)
Nucleic Acids Res
, vol.10
-
-
Lee, M.1
Aswani, A.2
Han, A.3
Tomlin, C.J.4
Dueber, J.E.5
-
14
-
-
84868263016
-
EPathBrick: a synthetic biology platform for engineering metabolic pathways in E. coli
-
Xu P., Vansiri A., Bhan N., Koffas M.A.G. ePathBrick: a synthetic biology platform for engineering metabolic pathways in E. coli. ACS Synth Biol 2012, 1:256-266.
-
(2012)
ACS Synth Biol
, vol.1
, pp. 256-266
-
-
Xu, P.1
Vansiri, A.2
Bhan, N.3
Koffas, M.A.G.4
-
15
-
-
84903766210
-
Efficient search, mapping, and optimization of multi-protein genetic systems in diverse bacteria
-
Farasat I., Kushwaha M., Collens J., Easterbrook M., Guido M., Howard M.Salis Efficient search, mapping, and optimization of multi-protein genetic systems in diverse bacteria. Mol Syst Biol 2014, 10.
-
(2014)
Mol Syst Biol
, vol.10
-
-
Farasat, I.1
Kushwaha, M.2
Collens, J.3
Easterbrook, M.4
Guido, M.5
Howard, M.S.6
-
16
-
-
79955145774
-
EMILiO: a fast algorithm for genome-scale strain design
-
Yang L., Cluett W.R., Mahadevan R. EMILiO: a fast algorithm for genome-scale strain design. Metab Eng 2011, 13:272-281.
-
(2011)
Metab Eng
, vol.13
, pp. 272-281
-
-
Yang, L.1
Cluett, W.R.2
Mahadevan, R.3
-
17
-
-
0242487787
-
Optknock: a bilevel programming framework for identifying gene knockout strategies for microbial strain optimization
-
Burgard A.P., Pharkya P., Maranas C.D. Optknock: a bilevel programming framework for identifying gene knockout strategies for microbial strain optimization. Biotechnol Bioeng 2003, 84:647-657.
-
(2003)
Biotechnol Bioeng
, vol.84
, pp. 647-657
-
-
Burgard, A.P.1
Pharkya, P.2
Maranas, C.D.3
-
18
-
-
0034612342
-
One-step inactivation of chromosomal genes in Escherichia coli K-12 using PCR products
-
Datsenko K.A., Wanner B.L. One-step inactivation of chromosomal genes in Escherichia coli K-12 using PCR products. Proc Natl Acad Sci U S A 2000, 97:6640-6645.
-
(2000)
Proc Natl Acad Sci U S A
, vol.97
, pp. 6640-6645
-
-
Datsenko, K.A.1
Wanner, B.L.2
-
19
-
-
84879744424
-
Rapid one-step inactivation of single or multiple genes in Escherichia coli
-
Song C.W., Lee S.Y. Rapid one-step inactivation of single or multiple genes in Escherichia coli. Biotechnol J 2013, 8:776-784.
-
(2013)
Biotechnol J
, vol.8
, pp. 776-784
-
-
Song, C.W.1
Lee, S.Y.2
-
20
-
-
84869010163
-
Mathematical optimization applications in metabolic networks
-
Zomorrodi A.R., Suthers P.F., Ranganathan S., Maranas C.D. Mathematical optimization applications in metabolic networks. Metab Eng 2012, 14:672-686.
-
(2012)
Metab Eng
, vol.14
, pp. 672-686
-
-
Zomorrodi, A.R.1
Suthers, P.F.2
Ranganathan, S.3
Maranas, C.D.4
-
21
-
-
84897954571
-
Characterizing bacterial gene circuit dynamics with optically programmed gene expression signals
-
Olson E.J., Hartsough L.A., Landry B.P., Shroff R., Tabor J.J. Characterizing bacterial gene circuit dynamics with optically programmed gene expression signals. Nat Methods 2014, 11:449-455.
-
(2014)
Nat Methods
, vol.11
, pp. 449-455
-
-
Olson, E.J.1
Hartsough, L.A.2
Landry, B.P.3
Shroff, R.4
Tabor, J.J.5
-
22
-
-
84868619337
-
Genetic programs constructed from layered logic gates in single cells
-
Moon T.S., Lou C., Tamsir A., Stanton B.C., Voigt C. Genetic programs constructed from layered logic gates in single cells. Nature 2012, 491:249-253.
-
(2012)
Nature
, vol.491
, pp. 249-253
-
-
Moon, T.S.1
Lou, C.2
Tamsir, A.3
Stanton, B.C.4
Voigt, C.5
-
23
-
-
84869451704
-
Genetic circuit performance under conditions relevant for industrial bioreactors
-
Moser F., Broers N.J., Hartmans S., Tamsir A., Kerkman R., Roubos J.A., Bovenberg R., Voigt C.A. Genetic circuit performance under conditions relevant for industrial bioreactors. ACS Synth Biol 2012, 1:555-564.
-
(2012)
ACS Synth Biol
, vol.1
, pp. 555-564
-
-
Moser, F.1
Broers, N.J.2
Hartmans, S.3
Tamsir, A.4
Kerkman, R.5
Roubos, J.A.6
Bovenberg, R.7
Voigt, C.A.8
-
24
-
-
84887622083
-
From the first drop to the first truckload: commercialization of microbial processes for renewable chemicals
-
Van Dien S. From the first drop to the first truckload: commercialization of microbial processes for renewable chemicals. Curr Opin Biotechnol 2013, 10.1016/j.copbio.2013.03.002.
-
(2013)
Curr Opin Biotechnol
-
-
Van Dien, S.1
-
25
-
-
84861440312
-
Systems metabolic engineering of microorganisms for natural and non-natural chemicals
-
Lee J.W., Na D., Park J.M., Lee J., Choi S., Lee S.Y. Systems metabolic engineering of microorganisms for natural and non-natural chemicals. Nat Chem Biol 2012, 8:536-546.
-
(2012)
Nat Chem Biol
, vol.8
, pp. 536-546
-
-
Lee, J.W.1
Na, D.2
Park, J.M.3
Lee, J.4
Choi, S.5
Lee, S.Y.6
-
26
-
-
84872434172
-
Dynamic strain scanning optimization: an efficient strain design strategy for balanced yield, titer, and productivity. DySScO strategy for strain design
-
Zhuang K., Yang L., Cluett W.R., Mahadevan R. Dynamic strain scanning optimization: an efficient strain design strategy for balanced yield, titer, and productivity. DySScO strategy for strain design. BMC Biotechnol 2013, 13:8.
-
(2013)
BMC Biotechnol
, vol.13
, pp. 8
-
-
Zhuang, K.1
Yang, L.2
Cluett, W.R.3
Mahadevan, R.4
-
27
-
-
78649694766
-
Genetic basis of growth adaptation of Escherichia coli after deletion of pgi, a major metabolic gene
-
Charusanti P., Conrad T.M., Knight E.M., Venkataraman K., Fong N.L., Xie B., Gao Y., Palsson B.Ø. Genetic basis of growth adaptation of Escherichia coli after deletion of pgi, a major metabolic gene. PLoS Genet 2010, 6:e1001186.
-
(2010)
PLoS Genet
, vol.6
, pp. e1001186
-
-
Charusanti, P.1
Conrad, T.M.2
Knight, E.M.3
Venkataraman, K.4
Fong, N.L.5
Xie, B.6
Gao, Y.7
Palsson, B.Ø.8
-
28
-
-
44249111668
-
Application of functional genomics to pathway optimization for increased isoprenoid production
-
Kizer L., Pitera D.J., Pfleger B.F., Keasling J.D. Application of functional genomics to pathway optimization for increased isoprenoid production. Appl Environ Microbiol 2008, 74:3229-3241.
-
(2008)
Appl Environ Microbiol
, vol.74
, pp. 3229-3241
-
-
Kizer, L.1
Pitera, D.J.2
Pfleger, B.F.3
Keasling, J.D.4
-
29
-
-
25144505718
-
In silico design and adaptive evolution of Escherichia coli for production of lactic acid
-
Fong S.S., Burgard A.P., Herring C.D., Knight E.M., Blattner F.R., Maranas C.D., Palsson B.O. In silico design and adaptive evolution of Escherichia coli for production of lactic acid. Biotechnol Bioeng 2005, 91:643-648.
-
(2005)
Biotechnol Bioeng
, vol.91
, pp. 643-648
-
-
Fong, S.S.1
Burgard, A.P.2
Herring, C.D.3
Knight, E.M.4
Blattner, F.R.5
Maranas, C.D.6
Palsson, B.O.7
-
30
-
-
84876325767
-
Tuning primary metabolism for heterologous pathway productivity
-
Solomon K.V., Moon T.S., Ma B., Sanders T.M., Prather K.L.J. Tuning primary metabolism for heterologous pathway productivity. ACS Synth Biol 2013, 2:126-135.
-
(2013)
ACS Synth Biol
, vol.2
, pp. 126-135
-
-
Solomon, K.V.1
Moon, T.S.2
Ma, B.3
Sanders, T.M.4
Prather, K.L.J.5
-
31
-
-
84869102255
-
A dynamic metabolite valve for the control of central carbon metabolism
-
Solomon K.V., Sanders T.M., Prather K.L.J. A dynamic metabolite valve for the control of central carbon metabolism. Metab Eng 2012, 14:661-671.
-
(2012)
Metab Eng
, vol.14
, pp. 661-671
-
-
Solomon, K.V.1
Sanders, T.M.2
Prather, K.L.J.3
-
32
-
-
12544260062
-
Estimating optimal profiles of genetic alterations using constraint-based models
-
Gadkar K.G., Doyle Iii F.J., Edwards J.S., Mahadevan R. Estimating optimal profiles of genetic alterations using constraint-based models. Biotechnol Bioeng 2005, 89:243-251.
-
(2005)
Biotechnol Bioeng
, vol.89
, pp. 243-251
-
-
Gadkar, K.G.1
Doyle Iii, F.J.2
Edwards, J.S.3
Mahadevan, R.4
-
33
-
-
50249115104
-
Dynamic metabolic engineering for increasing bioprocess productivity
-
Anesiadis N., Cluett W.R., Mahadevan R. Dynamic metabolic engineering for increasing bioprocess productivity. Metab Eng 2008, 10:255-266.
-
(2008)
Metab Eng
, vol.10
, pp. 255-266
-
-
Anesiadis, N.1
Cluett, W.R.2
Mahadevan, R.3
-
34
-
-
0028146781
-
Stoichiometric flux balance models quantitatively predict growth and metabolic by-product secretion in wild-type Escherichia coli W3110
-
Varma A., Palsson B.O. Stoichiometric flux balance models quantitatively predict growth and metabolic by-product secretion in wild-type Escherichia coli W3110. Appl Environ Microbiol 1994, 60:3724-3731.
-
(1994)
Appl Environ Microbiol
, vol.60
, pp. 3724-3731
-
-
Varma, A.1
Palsson, B.O.2
-
35
-
-
28444472789
-
Fermentation of 10% (w/v) sugar to D: (-)-lactate by engineered Escherichia coli B
-
Zhou S., Yomano L.P., Shanmugam K.T., Ingram L.O. Fermentation of 10% (w/v) sugar to D: (-)-lactate by engineered Escherichia coli B. Biotechnol Lett 2005, 27:1891-1896.
-
(2005)
Biotechnol Lett
, vol.27
, pp. 1891-1896
-
-
Zhou, S.1
Yomano, L.P.2
Shanmugam, K.T.3
Ingram, L.O.4
-
36
-
-
79954439764
-
Evaluation of genetic manipulation strategies on d-lactate production by Escherichia coli
-
Zhou L., Zuo Z.-R., Chen X.-Z., Niu D.-D., Tian K.-M., Prior B.A., Shen W., Shi G.-Y., Singh S., Wang Z.-X. Evaluation of genetic manipulation strategies on d-lactate production by Escherichia coli. Curr Microbiol 2011, 62:981-989.
-
(2011)
Curr Microbiol
, vol.62
, pp. 981-989
-
-
Zhou, L.1
Zuo, Z.-R.2
Chen, X.-Z.3
Niu, D.-D.4
Tian, K.-M.5
Prior, B.A.6
Shen, W.7
Shi, G.-Y.8
Singh, S.9
Wang, Z.-X.10
-
37
-
-
84896722895
-
Engineering the α-ketoglutarate overproduction from raw glycerol by overexpression of the genes encoding NADP+-dependent isocitrate dehydrogenase and pyruvate carboxylase in Yarrowia lipolytica
-
Yovkova V., Otto C., Aurich A., Mauersberger S., Barth G. Engineering the α-ketoglutarate overproduction from raw glycerol by overexpression of the genes encoding NADP+-dependent isocitrate dehydrogenase and pyruvate carboxylase in Yarrowia lipolytica. Appl Microbiol Biotechnol 2014, 98:2003-2013.
-
(2014)
Appl Microbiol Biotechnol
, vol.98
, pp. 2003-2013
-
-
Yovkova, V.1
Otto, C.2
Aurich, A.3
Mauersberger, S.4
Barth, G.5
-
38
-
-
84899679316
-
Recombinant protein expression in Escherichia coli: advances and challenges
-
Rosano G., Ceccarelli E. Recombinant protein expression in Escherichia coli: advances and challenges. Front Microbiol 2014, 5.
-
(2014)
Front Microbiol
, pp. 5
-
-
Rosano, G.1
Ceccarelli, E.2
-
39
-
-
73149088132
-
Engineering static and dynamic control of synthetic pathways
-
Holtz W.J., Keasling J.D. Engineering static and dynamic control of synthetic pathways. Cell 2010, 140:19-23.
-
(2010)
Cell
, vol.140
, pp. 19-23
-
-
Holtz, W.J.1
Keasling, J.D.2
-
40
-
-
84857050180
-
Applications of genetically-encoded biosensors for the construction and control of biosynthetic pathways
-
Michener J.K., Thodey K., Liang J.C., Smolke C.D. Applications of genetically-encoded biosensors for the construction and control of biosynthetic pathways. Metab Eng 2012, 14:212-222.
-
(2012)
Metab Eng
, vol.14
, pp. 212-222
-
-
Michener, J.K.1
Thodey, K.2
Liang, J.C.3
Smolke, C.D.4
-
41
-
-
0036708443
-
Dynamic flux balance analysis of diauxic growth in Escherichia coli
-
Mahadevan R., Edwards J.S., Doyle F.J. Dynamic flux balance analysis of diauxic growth in Escherichia coli. Biophys J 2002, 83:1331-1340.
-
(2002)
Biophys J
, vol.83
, pp. 1331-1340
-
-
Mahadevan, R.1
Edwards, J.S.2
Doyle, F.J.3
-
42
-
-
2942614884
-
Programmable cells: interfacing natural and engineered gene networks
-
Kobayashi H., Kaern M., Araki M., Chung K., Gardner T.S., Cantor C.R., Collins J.J. Programmable cells: interfacing natural and engineered gene networks. Proc Natl Acad Sci U S A 2004, 101:8414-8419.
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, pp. 8414-8419
-
-
Kobayashi, H.1
Kaern, M.2
Araki, M.3
Chung, K.4
Gardner, T.S.5
Cantor, C.R.6
Collins, J.J.7
-
43
-
-
84921442436
-
Quorum-sensing linked RNAi for dynamic pathway control in Saccharomyces cerevisiae
-
Williams T.C., Averesch N.J.H., Lekieffre N., Winter G., Vickers C.E., Nielsen L.K., Kromer J.O. Quorum-sensing linked RNAi for dynamic pathway control in Saccharomyces cerevisiae. Metab Eng 2014.
-
(2014)
Metab Eng
-
-
Williams, T.C.1
Averesch, N.J.H.2
Lekieffre, N.3
Winter, G.4
Vickers, C.E.5
Nielsen, L.K.6
Kromer, J.O.7
-
44
-
-
84865610553
-
Genetically switched d-lactate production in Escherichia coli
-
Zhou L., Niu D.-D., Tian K.-M., Chen X.-Z., Prior B.a, Shen W., Shi G.-Y., Singh S., Wang Z.-X. Genetically switched d-lactate production in Escherichia coli. Metab Eng 2012, 14:560-568.
-
(2012)
Metab Eng
, vol.14
, pp. 560-568
-
-
Zhou, L.1
Niu, D.-D.2
Tian, K.-M.3
Chen, X.-Z.4
Prior, B.5
Shen, W.6
Shi, G.-Y.7
Singh, S.8
Wang, Z.-X.9
-
45
-
-
84899628032
-
Metabolic flux redirection from a central metabolic pathway toward a synthetic pathway using a metabolic toggle switch
-
Soma Y., Tsuruno K., Wada M., Yokota A., Hanai T. Metabolic flux redirection from a central metabolic pathway toward a synthetic pathway using a metabolic toggle switch. Metab Eng 2014, 10.1016/j.ymben.2014.02.008.
-
(2014)
Metab Eng
-
-
Soma, Y.1
Tsuruno, K.2
Wada, M.3
Yokota, A.4
Hanai, T.5
-
46
-
-
0034024497
-
Improving lycopene production in Escherichia coli by engineering metabolic control
-
Farmer W.R., Liao J.C. Improving lycopene production in Escherichia coli by engineering metabolic control. Nat Biotechnol 2000, 18:533-537.
-
(2000)
Nat Biotechnol
, vol.18
, pp. 533-537
-
-
Farmer, W.R.1
Liao, J.C.2
-
47
-
-
79955806186
-
Engineering microbial biofuel tolerance and export using efflux pumps
-
Dunlop M.J., Dossani Z.Y., Szmidt H.L., Chu H.C., Lee T.S., Keasling J.D., Hadi M.Z., Mukhopadhyay A. Engineering microbial biofuel tolerance and export using efflux pumps. Mol Syst Biol 2011, 7:487.
-
(2011)
Mol Syst Biol
, vol.7
, pp. 487
-
-
Dunlop, M.J.1
Dossani, Z.Y.2
Szmidt, H.L.3
Chu, H.C.4
Lee, T.S.5
Keasling, J.D.6
Hadi, M.Z.7
Mukhopadhyay, A.8
-
48
-
-
77955852574
-
A model for improving microbial biofuel production using a synthetic feedback loop
-
Dunlop M.J., Keasling J.D., Mukhopadhyay A. A model for improving microbial biofuel production using a synthetic feedback loop. Syst Synth Biol 2010, 4:95-104.
-
(2010)
Syst Synth Biol
, vol.4
, pp. 95-104
-
-
Dunlop, M.J.1
Keasling, J.D.2
Mukhopadhyay, A.3
-
49
-
-
84875857527
-
Synthetic feedback loop model for increasing microbial biofuel production using a biosensor
-
Harrison M.E., Dunlop M.J. Synthetic feedback loop model for increasing microbial biofuel production using a biosensor. Front Microbiol 2012, 3:360.
-
(2012)
Front Microbiol
, vol.3
, pp. 360
-
-
Harrison, M.E.1
Dunlop, M.J.2
-
50
-
-
84887422015
-
Engineering dynamic pathway regulation using stress-response promoters
-
Dahl R.H., Zhang F., Alonso-Gutierrez J., Baidoo E., Batth T.S., Redding-Johanson A.M., Petzold C.J., Mukhopadhyay A., Lee T.S., Adams P.D., et al. Engineering dynamic pathway regulation using stress-response promoters. Nat Biotechnol 2013, 31:1039-1046.
-
(2013)
Nat Biotechnol
, vol.31
, pp. 1039-1046
-
-
Dahl, R.H.1
Zhang, F.2
Alonso-Gutierrez, J.3
Baidoo, E.4
Batth, T.S.5
Redding-Johanson, A.M.6
Petzold, C.J.7
Mukhopadhyay, A.8
Lee, T.S.9
Adams, P.D.10
-
51
-
-
84859633048
-
Design of a dynamic sensor-regulator system for production of chemicals and fuels derived from fatty acids
-
Zhang F., Carothers J.M., Keasling J.D. Design of a dynamic sensor-regulator system for production of chemicals and fuels derived from fatty acids. Nat Biotechnol 2012, 30:354-359.
-
(2012)
Nat Biotechnol
, vol.30
, pp. 354-359
-
-
Zhang, F.1
Carothers, J.M.2
Keasling, J.D.3
-
52
-
-
84896702596
-
Design and kinetic analysis of a hybrid promoter-regulator system for malonyl-CoA sensing in Escherichia coli
-
Xu P., Wang W., Li L., Bhan N., Zhang F., Koffas M.A.G. Design and kinetic analysis of a hybrid promoter-regulator system for malonyl-CoA sensing in Escherichia coli. ACS Chem Biol 2013, 9:451-458.
-
(2013)
ACS Chem Biol
, vol.9
, pp. 451-458
-
-
Xu, P.1
Wang, W.2
Li, L.3
Bhan, N.4
Zhang, F.5
Koffas, M.A.G.6
-
53
-
-
84905668376
-
Improving fatty acids production by engineering dynamic pathway regulation and metabolic control
-
Xu P., Li L., Zhang F., Stephanopoulos G., Koffas M. Improving fatty acids production by engineering dynamic pathway regulation and metabolic control. Proc Natl Acad Sci 2014, 111.
-
(2014)
Proc Natl Acad Sci
, pp. 111
-
-
Xu, P.1
Li, L.2
Zhang, F.3
Stephanopoulos, G.4
Koffas, M.5
-
54
-
-
84882603873
-
Analysis and design of a genetic circuit for dynamic metabolic control
-
Anesiadis N., Kobayashi H., Cluett W.R., Mahadevan R. Analysis and design of a genetic circuit for dynamic metabolic control. ACS Synth Biol 2013, 2:442-452.
-
(2013)
ACS Synth Biol
, vol.2
, pp. 442-452
-
-
Anesiadis, N.1
Kobayashi, H.2
Cluett, W.R.3
Mahadevan, R.4
-
55
-
-
77951107086
-
Synthetic biology: applications come of age
-
Khalil A.S., Collins J.J. Synthetic biology: applications come of age. Nat Rev Genet 2010, 11:367-379.
-
(2010)
Nat Rev Genet
, vol.11
, pp. 367-379
-
-
Khalil, A.S.1
Collins, J.J.2
-
56
-
-
84859842558
-
Rationally designed families of orthogonal RNA regulators of translation
-
Mutalik V.K., Qi L., Guimaraes J.C., Lucks J.B., Arkin A.P. Rationally designed families of orthogonal RNA regulators of translation. Nat Chem Biol 2012, 8:447-454.
-
(2012)
Nat Chem Biol
, vol.8
, pp. 447-454
-
-
Mutalik, V.K.1
Qi, L.2
Guimaraes, J.C.3
Lucks, J.B.4
Arkin, A.P.5
-
57
-
-
77649260489
-
Reengineering orthogonally selective riboswitches
-
Dixon N., Duncan J.N., Geerlings T., Dunstan M.S., McCarthy J.E.G., Leys D., Micklefield J. Reengineering orthogonally selective riboswitches. Proc Natl Acad Sci U S A 2010, 107:2830-2835.
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, pp. 2830-2835
-
-
Dixon, N.1
Duncan, J.N.2
Geerlings, T.3
Dunstan, M.S.4
McCarthy, J.E.G.5
Leys, D.6
Micklefield, J.7
-
58
-
-
79957700542
-
Versatile RNA-sensing transcriptional regulators for engineering genetic networks
-
Lucks J.B., Qi L., Mutalik V.K., Wang D., Arkin A.P. Versatile RNA-sensing transcriptional regulators for engineering genetic networks. Proc Natl Acad Sci U S A 2011, 108:8617-8622.
-
(2011)
Proc Natl Acad Sci U S A
, vol.108
, pp. 8617-8622
-
-
Lucks, J.B.1
Qi, L.2
Mutalik, V.K.3
Wang, D.4
Arkin, A.P.5
-
59
-
-
84872543206
-
A decade of riboswitches
-
Serganov A., Nudler E. A decade of riboswitches. Cell 2013, 152:17-24.
-
(2013)
Cell
, vol.152
, pp. 17-24
-
-
Serganov, A.1
Nudler, E.2
-
60
-
-
80052973462
-
Prospects for riboswitch discovery and analysis
-
Breaker R.R. Prospects for riboswitch discovery and analysis. Mol Cell 2011, 43:867-879.
-
(2011)
Mol Cell
, vol.43
, pp. 867-879
-
-
Breaker, R.R.1
-
61
-
-
0142075327
-
Genetic control by metabolite-binding riboswitches
-
Winkler W.C., Breaker R.R. Genetic control by metabolite-binding riboswitches. Chembiochem 2003, 4:1024-1032.
-
(2003)
Chembiochem
, vol.4
, pp. 1024-1032
-
-
Winkler, W.C.1
Breaker, R.R.2
-
62
-
-
84867195988
-
Synthetic RNA switches as a tool for temporal and spatial control over gene expression
-
Chang A.L., Wolf J.J., Smolke C.D. Synthetic RNA switches as a tool for temporal and spatial control over gene expression. Curr Opin Biotechnol 2012, 23:679-688.
-
(2012)
Curr Opin Biotechnol
, vol.23
, pp. 679-688
-
-
Chang, A.L.1
Wolf, J.J.2
Smolke, C.D.3
-
63
-
-
0030024281
-
Role of a peptide tagging system in degradation of proteins synthesized from damaged messenger RNA
-
Keiler K.C., Waller P.R., Sauer R.T. Role of a peptide tagging system in degradation of proteins synthesized from damaged messenger RNA. Science 1996, 271:990-993.
-
(1996)
Science
, vol.271
, pp. 990-993
-
-
Keiler, K.C.1
Waller, P.R.2
Sauer, R.T.3
-
64
-
-
84879960190
-
Tailored fatty acid synthesis via dynamic control of fatty acid elongation
-
Torella J.P., Ford T.J., Kim S.N., Chen A.M., Way J.C., Silver P.A. Tailored fatty acid synthesis via dynamic control of fatty acid elongation. Proc Natl Acad Sci U S A 2013, 110:11290-11295.
-
(2013)
Proc Natl Acad Sci U S A
, vol.110
, pp. 11290-11295
-
-
Torella, J.P.1
Ford, T.J.2
Kim, S.N.3
Chen, A.M.4
Way, J.C.5
Silver, P.A.6
-
65
-
-
77149120797
-
Acetylation of metabolic enzymes coordinates carbon source utilization and metabolic flux
-
Wang Q., Zhang Y., Yang C., Xiong H., Lin Y., Yao J., Li H., Xie L., Zhao W., Yao Y., et al. Acetylation of metabolic enzymes coordinates carbon source utilization and metabolic flux. Science 2010, 327:1004-1007.
-
(2010)
Science
, vol.327
, pp. 1004-1007
-
-
Wang, Q.1
Zhang, Y.2
Yang, C.3
Xiong, H.4
Lin, Y.5
Yao, J.6
Li, H.7
Xie, L.8
Zhao, W.9
Yao, Y.10
-
66
-
-
84873343462
-
Comprehensive profiling of protein lysine acetylation in Escherichia coli
-
Zhang K., Zheng S., Yang J. Comprehensive profiling of protein lysine acetylation in Escherichia coli. J Proteome Res 2013, 12.
-
(2013)
J Proteome Res
, vol.12
-
-
Zhang, K.1
Zheng, S.2
Yang, J.3
-
67
-
-
28444460297
-
Global analysis of protein phosphorylation in yeast
-
Ptacek J., Devgan G., Michaud G., Zhu H., Zhu X., Fasolo J., Guo H., Jona G., Breitkreutz A., Sopko R., et al. Global analysis of protein phosphorylation in yeast. Nature 2005, 438:679-684.
-
(2005)
Nature
, vol.438
, pp. 679-684
-
-
Ptacek, J.1
Devgan, G.2
Michaud, G.3
Zhu, H.4
Zhu, X.5
Fasolo, J.6
Guo, H.7
Jona, G.8
Breitkreutz, A.9
Sopko, R.10
-
68
-
-
84869430619
-
Regulation of yeast central metabolism by enzyme phosphorylation
-
Oliveira A.P., Ludwig C., Picotti P., Kogadeeva M., Aebersold R., Sauer U. Regulation of yeast central metabolism by enzyme phosphorylation. Mol Syst Biol 2012, 8:623.
-
(2012)
Mol Syst Biol
, vol.8
, pp. 623
-
-
Oliveira, A.P.1
Ludwig, C.2
Picotti, P.3
Kogadeeva, M.4
Aebersold, R.5
Sauer, U.6
-
69
-
-
84899047521
-
Coordination of microbial metabolism
-
Chubukov V., Gerosa L., Kochanowski K., Sauer U. Coordination of microbial metabolism. Nat Rev Microbiol 2014, 12:327-340.
-
(2014)
Nat Rev Microbiol
, vol.12
, pp. 327-340
-
-
Chubukov, V.1
Gerosa, L.2
Kochanowski, K.3
Sauer, U.4
-
71
-
-
0037162469
-
Global analysis of mRNA decay and abundance in Escherichia coli at single-gene resolution using two-color fluorescent DNA microarrays
-
Bernstein J.A., Khodursky A.B., Lin P.-H., Lin-Chao S., Cohen S.N. Global analysis of mRNA decay and abundance in Escherichia coli at single-gene resolution using two-color fluorescent DNA microarrays. Proc Natl Acad Sci U S A 2002, 99:9697-9702.
-
(2002)
Proc Natl Acad Sci U S A
, vol.99
, pp. 9697-9702
-
-
Bernstein, J.A.1
Khodursky, A.B.2
Lin, P.-H.3
Lin-Chao, S.4
Cohen, S.N.5
-
72
-
-
0037197892
-
Precision and functional specificity in mRNA decay
-
Wang Y., Liu C.L., Storey J.D., Tibshirani R.J., Herschlag D., Brown P.O. Precision and functional specificity in mRNA decay. Proc Natl Acad Sci U S A 2002, 99:5860-5865.
-
(2002)
Proc Natl Acad Sci U S A
, vol.99
, pp. 5860-5865
-
-
Wang, Y.1
Liu, C.L.2
Storey, J.D.3
Tibshirani, R.J.4
Herschlag, D.5
Brown, P.O.6
-
73
-
-
0018939306
-
Metabolism of individual proteins in exponentially growing Escherichia coli
-
Mosteller R., Goldstein R., Nishimoto K. Metabolism of individual proteins in exponentially growing Escherichia coli. J Biol Chem 1980, 255:2524-2532.
-
(1980)
J Biol Chem
, vol.255
, pp. 2524-2532
-
-
Mosteller, R.1
Goldstein, R.2
Nishimoto, K.3
-
74
-
-
0018856008
-
The relative rates of protein synthesis and degradation in a growing culture of Escherichia coli
-
Larrabee K., Phillips J. The relative rates of protein synthesis and degradation in a growing culture of Escherichia coli. J Biol Chem 1980, 25:4125-4130.
-
(1980)
J Biol Chem
, vol.25
, pp. 4125-4130
-
-
Larrabee, K.1
Phillips, J.2
-
75
-
-
0016908233
-
Intracellular protein degradation in mammalian and bacterial cells: Part 2
-
Goldberg A., John A.St. Intracellular protein degradation in mammalian and bacterial cells: Part 2. Annu Rev Biochem 1976, 43:747-803.
-
(1976)
Annu Rev Biochem
, vol.43
, pp. 747-803
-
-
Goldberg, A.1
John, A.2
-
78
-
-
84867389802
-
RNA processing enables predictable programming of gene expression
-
Qi L., Haurwitz R., Shao W. RNA processing enables predictable programming of gene expression. Nat Biotechnol 2012, 30:1002-1006.
-
(2012)
Nat Biotechnol
, vol.30
, pp. 1002-1006
-
-
Qi, L.1
Haurwitz, R.2
Shao, W.3
-
79
-
-
84869476328
-
Ribozyme-based insulator parts buffer synthetic circuits from genetic context
-
Lou C., Stanton B., Chen Y., Munsky B., Voigt C. Ribozyme-based insulator parts buffer synthetic circuits from genetic context. Nat Biotechnol 2012, 30:1137-1142.
-
(2012)
Nat Biotechnol
, vol.30
, pp. 1137-1142
-
-
Lou, C.1
Stanton, B.2
Chen, Y.3
Munsky, B.4
Voigt, C.5
-
80
-
-
84869462746
-
Insulating gene circuits from context by RNA processing
-
Bashor C., Collins J. Insulating gene circuits from context by RNA processing. Nat Biotechnol 2012, 30:1061-1063.
-
(2012)
Nat Biotechnol
, vol.30
, pp. 1061-1063
-
-
Bashor, C.1
Collins, J.2
-
81
-
-
72249097352
-
Growth rate-dependent global effects on gene expression in bacteria
-
Klumpp S., Zhang Z., Hwa T. Growth rate-dependent global effects on gene expression in bacteria. Cell 2009, 139:1366-1375.
-
(2009)
Cell
, vol.139
, pp. 1366-1375
-
-
Klumpp, S.1
Zhang, Z.2
Hwa, T.3
-
82
-
-
78449268845
-
Interdependence of cell growth and gene expression: origins and consequences
-
Scott M., Gunderson C.W., Mateescu E.M., Zhang Z., Hwa T. Interdependence of cell growth and gene expression: origins and consequences. Science 2010, 330:1099-1102.
-
(2010)
Science
, vol.330
, pp. 1099-1102
-
-
Scott, M.1
Gunderson, C.W.2
Mateescu, E.M.3
Zhang, Z.4
Hwa, T.5
-
83
-
-
84893398632
-
Bacterial growth: global effects on gene expression, growth feedback and proteome partition
-
Klumpp S., Hwa T. Bacterial growth: global effects on gene expression, growth feedback and proteome partition. Curr Opin Biotechnol 2014, 28C:96-102.
-
(2014)
Curr Opin Biotechnol
, vol.28 C
, pp. 96-102
-
-
Klumpp, S.1
Hwa, T.2
-
84
-
-
80054069179
-
A comprehensive genome-scale reconstruction of Escherichia coli metabolism-2011
-
Orth J.D., Conrad T.M., Na J., Lerman J.A., Nam H., Feist A.M., Palsson B.Ø. A comprehensive genome-scale reconstruction of Escherichia coli metabolism-2011. Mol Syst Biol 2011, 7:535.
-
(2011)
Mol Syst Biol
, vol.7
, pp. 535
-
-
Orth, J.D.1
Conrad, T.M.2
Na, J.3
Lerman, J.A.4
Nam, H.5
Feist, A.M.6
Palsson, B.Ø.7
-
85
-
-
84858439602
-
Constraining the metabolic genotype-phenotype relationship using a phylogeny of in silico methods
-
Lewis N.E., Nagarajan H., Palsson B.O. Constraining the metabolic genotype-phenotype relationship using a phylogeny of in silico methods. Nat Rev Microbiol 2012, 10:291-305.
-
(2012)
Nat Rev Microbiol
, vol.10
, pp. 291-305
-
-
Lewis, N.E.1
Nagarajan, H.2
Palsson, B.O.3
-
86
-
-
84896731390
-
Enumeration of smallest intervention strategies in genome-scale metabolic networks
-
Von Kamp A., Klamt S. Enumeration of smallest intervention strategies in genome-scale metabolic networks. PLoS Comput Biol 2014, 10:e1003378.
-
(2014)
PLoS Comput Biol
, vol.10
, pp. e1003378
-
-
Von Kamp, A.1
Klamt, S.2
|