Processing of double-R-loops in (CAG)•(CTG) and C9orf72 (GGGGCC)•(GGCCCC) repeats causes instability

Nucleic Acids Research

Volumn 42, Issue 16, 2014, Pages 10473-10487

  Reddy, Kaalak ^a,b,e   Schmidt, Monika H M ^a,b   Geist, Jaimie M ^a,c   Thakkar, Neha P ^a,b   Panigrahi, Gagan B ^a,b   Wang, Yuh Hwa ^d   Pearson, Christopher E ^a,b  

^a HOSPITAL FOR SICK CHILDREN   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

^c LAURENTIAN UNIVERSITY   (Canada)

^d UNIVERSITY OF VIRGINIA   (United States)

^e UNIVERSITY OF EDINBURGH   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE; CYTIDINE; RIBONUCLEASE H; THYMIDINE; C9ORF72 PROTEIN, HUMAN; DNA; PROTEIN; REPETITIVE DNA; RNA;

ARTICLE; C9ORF72 GENE; CAG REPEAT; CONTROLLED STUDY; CTG REPEAT; DNA MODIFICATION; DNA REPLICATION; DNA STRUCTURE; DOUBLE R LOOP; GENE; GENETIC ASSOCIATION; GENOMIC INSTABILITY; GGCCCC REPEAT; GGGGCC REPEAT; HELA CELL LINE; HUMAN; HUMAN CELL; NONHUMAN; NUCLEIC ACID ANALYSIS; NUCLEIC ACID STRUCTURE; NUCLEOTIDE REPEAT; NUCLEOTIDE SEQUENCE; R LOOP PROCESSING ASSAY; CHEMISTRY; GENETICS; METABOLISM; NERVE CELL; TRINUCLEOTIDE REPEAT; TUMOR CELL LINE;

CELL LINE, TUMOR; DNA; DNA REPEAT EXPANSION; GENOMIC INSTABILITY; HELA CELLS; HUMANS; NEURONS; PROTEINS; RIBONUCLEASE H; RNA; TRINUCLEOTIDE REPEAT EXPANSION;

EID: 84921417056     PISSN: 03051048     EISSN: 13624962     Source Type: Journal    
DOI: 10.1093/nar/gku658     Document Type: Article

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