CTG/CAG repeat instability is modulated by the levels of human DNA ligase I and its interaction with proliferating cell nuclear antigen. A distinction between replication and slipped-DNA repair

Journal of Biological Chemistry

Volumn 284, Issue 39, 2009, Pages 26631-26645

  Castel, Arturo López ^a   Tomkinson, Alan E ^b   Pearson, Christopher E ^a,c  

^a HOSPITAL FOR SICK CHILDREN   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

^c UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DNA LIGASES; DNA LIGATION; DNA REPAIR; HUMAN CELLS; MYOTONIC DYSTROPHY; OVER-EXPRESSION; POTENTIAL SOURCES; PROLIFERATING CELL NUCLEAR ANTIGENS; PURIFIED PROTEIN; REPLICATION PROCESS; STEADY-STATE LEVEL; TRANSGENIC MICE;

ANTIGENS; CELL MEMBRANES; DNA; ENZYMES; GENES; NUCLEIC ACIDS; REPAIR;

STABILITY;

ADENINE; ARGININE; CYCLINE; CYTOSINE; DNA; GUANINE; POLYDEOXYRIBONUCLEOTIDE SYNTHASE; POLYDEOXYRIBONUCLEOTIDE SYNTHASE 1; THYMINE; TRYPTOPHAN; UNCLASSIFIED DRUG;

ARTICLE; CELL LINE; CONTROLLED STUDY; DNA EXTRACTION; DNA REPAIR; GENE MUTATION; GENE OVEREXPRESSION; GENE REPLICATION; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; IN VITRO STUDY; MUTANT; MYOTONIC DYSTROPHY; PRIORITY JOURNAL; PROTEIN INTERACTION; PROTEIN PHOSPHORYLATION; PROTEIN PURIFICATION; TRANSGENIC MOUSE; TRINUCLEOTIDE REPEAT;

BLOTTING, WESTERN; CELL CYCLE; CELL LINE; DNA LIGASES; DNA REPAIR; DNA REPLICATION; HUMANS; MODELS, BIOLOGICAL; MUTATION; PHOSPHORYLATION; PROLIFERATING CELL NUCLEAR ANTIGEN; PROTEIN BINDING; TRANSFECTION; TRINUCLEOTIDE REPEATS;

MUS MUSCULUS;

EID: 70350374346     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M109.034405     Document Type: Article

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