The specificity loop of T7 RNA polymerase interacts first with the promoter and then with the elongating transcript, suggesting a mechanism for promoter clearance

Proceedings of the National Academy of Sciences of the United States of America

Volumn 97, Issue 26, 2000, Pages 14109-14114

  Temiakov, Dmitry ^a   Mentesana, Pamela E ^a,c   Ma, Kaiyu ^a   Mustaev, Arkady ^b   Borukhov, Sergei ^a   McAllister, William T ^a  

^a SUNY DOWNSTATE MEDICAL CENTER   (United States)

^b PUBLIC HEALTH RESEARCH INSTITUTE   (United States)

^c STONY BROOK UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DNA; RNA; RNA POLYMERASE;

ARTICLE; BACTERIOPHAGE T7; CROSS LINKING; GENE EXPRESSION REGULATION; MOLECULAR RECOGNITION; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN DNA INTERACTION; PROTEIN RNA BINDING; TRANSCRIPTION REGULATION;

BACTERIOPHAGE T7; BINDING SITES; CROSS-LINKING REAGENTS; DNA-DIRECTED RNA POLYMERASES; MODELS, MOLECULAR; PROMOTER REGIONS (GENETICS); TRANSCRIPTION, GENETIC; VIRAL PROTEINS;

EID: 0034687683     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.250473197     Document Type: Article

References (31)

1. McAllister, W. T. (1997) in Transcription by T7 RNA Polymerase, Nucleic Acids and Molecular Biology, eds. Eckstein, F. & Lilley, D. M. J. (Springer, Berlin), Vol. 11, pp. 15-25.
2. Raskin, C. A., Diaz, G. A. & McAllister, W. T. (1993) Proc. Natl. Acad. Sci. USA 90, 3147-3151.
3. Cheetham, G., Jeruzalmi, D. & Steitz, T. A. (1999) Nature (London) 399, 80-83.
4. Ikeda, R. A. & Richardson, C. C. (1986) Proc. Natl. Acad. Sci. USA 83, 3614-3618.
5. Place, C., Oddos, J., Buc, H., McAllister, W. T. & Buckle, M. (1999) Biochemistry 38, 4948-4957.
6. Cheetham, G. & Steitz, T. A. (1999) Science 286, 2305-2309.
7. Martin, C. T., Muller, D. K. & Coleman, J. E. (1988) Biochemistry 27, 3966-3974.
8. Mentesana, P. E., Chin-Bow, S. T., Sousa, R. & McAllister, W. T. (2000) J. Mol. Biol., in press.
9. Muller, D. K., Martin, C. T. & Coleman, J. E. (1988) Biochemistry 27, 5763-5771.
10. He, B., Rong, M., Lyakhov, D. L., Gartenstein, H., Diaz, G. A., Castagna, R. C., McAllister, W. T. & Durbin, R. K. (1997) Protein Expression Purif. 9, 142-151.
11. Temiakov, D., Mentesana, P. E. & McAllister, W. T. (2000) in Characterization of T7 RNA Polymerase Protein:DNA Interactions During the Initiation and Elongation Phases, Protein:DNA Interactions: A Practical Approach, eds. Travers, A. A., Buckle, M. & Hames, B. D. (Oxford Univ. Press, Oxford, U.K.), pp. 351-364.
12. Karasavas, P. E. (1998) Dissertation (State University of New York, Brooklyn, NY).
13. Nudler, E., Mustaev, A., Lukhtanov, E. A. & Goldfarb, A. (1997) Cell 89, 33-41.
14. Sambrook, J., Fritsch, E. F. & Maniatis, T. (1989) Molecular Cloning: A Laboratory Manual (Cold Spring Harbor Lab. Press, Plainview, NY), 2nd Ed.
15. Korzheva, N., Mustaev, A., Kozlov, M., Malhotra, A., Nikiforov, V., Goldfarb, A. & Darst, S. A. (2000) Science 289, 619-624.
16. Tyagarajan, K., Monforte, J. A. & Hearst, J. E. (1991) Biochemistry 30, 10920-10924.
17. Markovtsov, V., Mustaev, A. & Goldfarb, A. (1996) Proc. Natl. Acad. Sci. USA 93, 3221-3226.
18. Sousa, R., Chung, Y. J., Rose, J. P. & Wang, B. C. (1993) Nature (London) 364, 593-599.
19. Jeruzalmi, D. & Steitz, T. A. (1998) EMBO J. 17, 4101-4113.
20. Eom, S. H., Wang, J. & Steitz, T. A. (1996) Nature (London) 382, 278-281.
21. Sastry, S. S. & Ross, B. M. (1998) Proc. Natl. Acad. Sci. USA 95, 9111-9116.
22. He, B., Rong, M., Durbin, R. K. & McAllister, W. T. (1997) J. Mol. Biol. 265, 275-288.
23. Lyakhov, D. L., He, B., Zhang, X., Studier, F. W., Dunn, J. J. & McAllister, W. T. (1997) J. Mol. Biol. 269, 28-40.
24. Macdonald, L. E., Durbin, R. K., Dunn, J. J. & McAllister, W. T. (1994) J. Mol. Biol. 238, 145-158.
25. He, B., Kukarin, A., Temiakov, D., Chin-Bow, S. T., Lyakhov, D. L., Rong, M., Durbin, R. K. & McAllister, W. T. (1998) J. Biol. Chem. 273, 18802-18811.
26. Bonner, G., Lafer, E. M. & Sousa, R. (1994) J. Biol. Chem. 269, 25129-25136.
27. Sousa, R. (1997) in Fundamental Aspects of T7 RNA Polymerase Structure and Mechanism, Nucleic Acids and Molecular Biology, eds. Eckstein, F. & Lilley, D. M. J. (Springer, Berlin), Vol. 11, pp. 1-14.
28. Sousa, R., Patra, D. & Lafer, E. M. (1992) J. Mol. Biol. 224, 319-334.
29. Mooney, R. A. & Landick, R. (1999) Cell 98, 687-690.
30. Zhang, G., Campbell, E. A., Minakhin, L., Richter, C., Severinov, K. & Darst, S. A. (1999) Cell 98, 811-824.
31. Lischwe, M. A. & Sung, M. T. (1977) J. Biol. Chem. 252, 4976-4980.