Interconverting conformations of slipped-DNA junctions formed by trinucleotide repeats affect repair outcome

Biochemistry

Volumn 52, Issue 5, 2013, Pages 773-785

  Slean, Meghan M ^a,b   Reddy, Kaalak ^a,b   Wu, Bin ^c   Nichol Edamura, Kerrie ^a,e   Kekis, Mariana ^a,b   Nelissen, Frank H T ^c   Aspers, Ruud L E G ^c   Tessari, Marco ^c   Schärer, Orlando D ^d   Wijmenga, Sybren S ^c   Pearson, Christopher E ^a,b  

^a HOSPITAL FOR SICK CHILDREN   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

^c RADBOUD UNIVERSITY NIJMEGEN   (Netherlands)

^d STONY BROOK UNIVERSITY   (United States)

^e Sanofi Pasteur Ltd   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENTARY STRAND; DNA REPAIR PROTEINS; HIGHER EFFICIENCY; NEUROLOGICAL DISEASE; TRANSIENT INTERMEDIATE;

CONFORMATIONS; DNA; EXPANSION; NUCLEOTIDES;

REPAIR;

NUCLEOTIDE;

ARTICLE; CAG REPEAT; DNA CONFORMATION; DNA REPAIR; DNA STRUCTURE; EXCISION REPAIR; MUTATION; PRIORITY JOURNAL; SLIPPED DNA JUNCTION; TRINUCLEOTIDE REPEAT;

BASE PAIRING; BASE SEQUENCE; DNA; DNA REPAIR; DNA-BINDING PROTEINS; ENDONUCLEASES; HELA CELLS; HMGB1 PROTEIN; HUMANS; MOLECULAR SEQUENCE DATA; MUTS DNA MISMATCH-BINDING PROTEIN; NUCLEAR PROTEINS; NUCLEIC ACID CONFORMATION; OLIGONUCLEOTIDES; PROTEIN BINDING; TRANSCRIPTION FACTORS; TRINUCLEOTIDE REPEATS;

EID: 84873330287     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi301369b     Document Type: Article

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