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Volumn 21, Issue 4, 2015, Pages 1468-1473

Copper-catalyzed difunctionalization of activated alkynes by radical oxidation-tandem cyclization/dearomatization to synthesize 3-trifluoromethyl spiro[4.5]trienones

Author keywords

Copper; Cyclization; Radical reactions; Tandem reactions; Trifluoromethylation

Indexed keywords

CARBON; CATALYSIS; COPPER; HYDROCARBONS; REACTION KINETICS;

EID: 84920997006     PISSN: 09476539     EISSN: 15213765     Source Type: Journal    
DOI: 10.1002/chem.201405672     Document Type: Article
Times cited : (130)

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    • CCDC 1015693 (2a) contains the supplementary crystallographic data for this paper. These data can be obtained free of charge from The Cambridge Crystallographic Data Centre via See the Supporting Information
    • CCDC 1015693 (2a) contains the supplementary crystallographic data for this paper. These data can be obtained free of charge from The Cambridge Crystallographic Data Centre via www.ccdc.cam.ac.uk/data- request/cif (See the Supporting Information).
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    • We considered another plausible process (from intermediate B to 2a), whereby, through a single-electron transfer (SET) process, intermediate C is generated from B and then oxidation of C with TBHP and MnO 2 affords the desired product 2a.
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    • In the course of preparation of this Communication, three reports of similar alkyne trifluoromethylations were published, see:


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.