메뉴 건너뛰기




Volumn 14, Issue 11, 2014, Pages 1-7

Overlap of Genetic Susceptibility to Type 1 Diabetes, Type 2 Diabetes, and Latent Autoimmune Diabetes in Adults

Author keywords

Genome wide association studies; HLA; Latent autoimmune diabetes in adults; TCF7L2; Type 1 diabetes; Type 2 diabetes

Indexed keywords

ALPHA AMIDATING ENZYME; C PEPTIDE; CATHEPSIN H; CD69 ANTIGEN; COMPLEMENT COMPONENT C1Q; CYCLIN D2; CYCLIN DEPENDENT KINASE INHIBITOR 2A; GLUTAMATE DECARBOXYLASE ANTIBODY; HEPATOCYTE NUCLEAR FACTOR 1; INTERLEUKIN 10; INTERLEUKIN 19; INTERLEUKIN 20; INTERLEUKIN 27; PROTEIN A; SOMATOMEDIN B; SOMATOSTATIN RECEPTOR 3; TRANSCRIPTION FACTOR 7 LIKE 2; AUTOANTIBODY; T CELL FACTOR PROTEIN; TCF7L2 PROTEIN, HUMAN;

EID: 84920918042     PISSN: 15344827     EISSN: 15390829     Source Type: Journal    
DOI: 10.1007/s11892-014-0550-9     Document Type: Review
Times cited : (38)

References (84)
  • 1
    • 0034932098 scopus 로고    scopus 로고
    • The accelerator hypothesis: weight gain as the missing link between type I and type II diabetes
    • COI: 1:CAS:528:DC%2BD3MXks1OrtLg%3D, PID: 11508279
    • Wilkin TJ. The accelerator hypothesis: weight gain as the missing link between type I and type II diabetes. Diabetologia. 2001;44:914–22.
    • (2001) Diabetologia , vol.44 , pp. 914-922
    • Wilkin, T.J.1
  • 2
    • 0034971563 scopus 로고    scopus 로고
    • Progress in the characterization of slowly progressive autoimmune diabetes in adult patients (LADA or type 1.5 diabetes)
    • COI: 1:CAS:528:DC%2BD3MXlslKgtbo%3D, PID: 11460597
    • Schernthaner G, Hink S, Kopp HP, Muzyka B, Streit G, Kroiss A. Progress in the characterization of slowly progressive autoimmune diabetes in adult patients (LADA or type 1.5 diabetes). Exp Clin Endocrinol Diabetes. 2001;109 Suppl 2:S94–S108.
    • (2001) Exp Clin Endocrinol Diabetes , vol.109 , pp. S94-S108
    • Schernthaner, G.1    Hink, S.2    Kopp, H.P.3    Muzyka, B.4    Streit, G.5    Kroiss, A.6
  • 3
    • 48249136253 scopus 로고    scopus 로고
    • Association analysis of type 2 diabetes loci in type 1 diabetes
    • COI: 1:CAS:528:DC%2BD1cXosVKlt78%3D, PID: 18426861
    • Qu HQ, Grant SF, Bradfield JP, et al. Association analysis of type 2 diabetes loci in type 1 diabetes. Diabetes. 2008;57:1983–6.
    • (2008) Diabetes , vol.57 , pp. 1983-1986
    • Qu, H.Q.1    Grant, S.F.2    Bradfield, J.P.3
  • 4
    • 0032955251 scopus 로고    scopus 로고
    • Clinical and genetic characteristics of type 2 diabetes with and without GAD antibodies
    • COI: 1:CAS:528:DyaK1MXhvFSjug%3D%3D, PID: 9892237
    • Tuomi T, Carlsson A, Li H, et al. Clinical and genetic characteristics of type 2 diabetes with and without GAD antibodies. Diabetes. 1999;48:150–7.
    • (1999) Diabetes , vol.48 , pp. 150-157
    • Tuomi, T.1    Carlsson, A.2    Li, H.3
  • 5
    • 0027500697 scopus 로고
    • Antibodies to glutamic acid decarboxylase reveal latent autoimmune diabetes mellitus in adults with a non-insulin-dependent onset of disease
    • COI: 1:STN:280:DyaK3s7ks1ansA%3D%3D, PID: 8425674
    • Tuomi T, Groop LC, Zimmet PZ, Rowley MJ, Knowles W, Mackay IR. Antibodies to glutamic acid decarboxylase reveal latent autoimmune diabetes mellitus in adults with a non-insulin-dependent onset of disease. Diabetes. 1993;42:359–62.
    • (1993) Diabetes , vol.42 , pp. 359-362
    • Tuomi, T.1    Groop, L.C.2    Zimmet, P.Z.3    Rowley, M.J.4    Knowles, W.5    Mackay, I.R.6
  • 6
    • 0031851293 scopus 로고    scopus 로고
    • Definition, diagnosis and classification of diabetes mellitus and its complications. Part 1: diagnosis and classification of diabetes mellitus provisional report of a WHO consultation
    • COI: 1:STN:280:DyaK1czkvFCrsA%3D%3D, PID: 9686693
    • Alberti KG, Zimmet PZ. Definition, diagnosis and classification of diabetes mellitus and its complications. Part 1: diagnosis and classification of diabetes mellitus provisional report of a WHO consultation. Diabet Med. 1998;15:539–53.
    • (1998) Diabet Med , vol.15 , pp. 539-553
    • Alberti, K.G.1    Zimmet, P.Z.2
  • 7
  • 8
    • 0031560175 scopus 로고    scopus 로고
    • UKPDS 25: autoantibodies to islet-cell cytoplasm and glutamic acid decarboxylase for prediction of insulin requirement in type 2 diabetes. UK Prospective Diabetes Study Group
    • COI: 1:STN:280:DyaK1c%2FitVakuw%3D%3D, PID: 9357409
    • Turner R, Stratton I, Horton V, et al. UKPDS 25: autoantibodies to islet-cell cytoplasm and glutamic acid decarboxylase for prediction of insulin requirement in type 2 diabetes. UK Prospective Diabetes Study Group. Lancet. 1997;350:1288–93.
    • (1997) Lancet , vol.350 , pp. 1288-1293
    • Turner, R.1    Stratton, I.2    Horton, V.3
  • 9
    • 0025094344 scopus 로고
    • Mapping genes in diabetes. Genetic epidemiological perspective
    • COI: 1:CAS:528:DyaK3MXhtlKktL4%3D, PID: 2227105
    • Rich SS. Mapping genes in diabetes. Genetic epidemiological perspective. Diabetes. 1990;39:1315–9.
    • (1990) Diabetes , vol.39 , pp. 1315-1319
    • Rich, S.S.1
  • 10
    • 68249108329 scopus 로고    scopus 로고
    • Prediction and interaction in complex disease genetics: experience in type 1 diabetes
    • PID: 19584936
    • Clayton DG. Prediction and interaction in complex disease genetics: experience in type 1 diabetes. PLoS Genet. 2009;5:e1000540.
    • (2009) PLoS Genet , vol.5 , pp. e1000540
    • Clayton, D.G.1
  • 11
    • 33745240931 scopus 로고    scopus 로고
    • A genome-wide association study of nonsynonymous SNPs identifies a type 1 diabetes locus in the interferon-induced helicase (IFIH1) region
    • COI: 1:CAS:528:DC%2BD28XltVOhur4%3D, PID: 16699517
    • Smyth DJ, Cooper JD, Bailey R, et al. A genome-wide association study of nonsynonymous SNPs identifies a type 1 diabetes locus in the interferon-induced helicase (IFIH1) region. Nat Genet. 2006;38:617–9.
    • (2006) Nat Genet , vol.38 , pp. 617-619
    • Smyth, D.J.1    Cooper, J.D.2    Bailey, R.3
  • 12
    • 34347341846 scopus 로고    scopus 로고
    • Robust associations of four new chromosome regions from genome-wide analyses of type 1 diabetes
    • COI: 1:CAS:528:DC%2BD2sXmvFKlsLo%3D, PID: 17554260
    • Todd JA, Walker NM, Cooper JD, et al. Robust associations of four new chromosome regions from genome-wide analyses of type 1 diabetes. Nat Genet. 2007;39:857–64.
    • (2007) Nat Genet , vol.39 , pp. 857-864
    • Todd, J.A.1    Walker, N.M.2    Cooper, J.D.3
  • 13
    • 42449094966 scopus 로고    scopus 로고
    • A novel susceptibility locus for type 1 diabetes on Chr12q13 identified by a genome-wide association study
    • COI: 1:CAS:528:DC%2BD1cXksVGrsrc%3D, PID: 18198356
    • Hakonarson H, Qu HQ, Bradfield JP, et al. A novel susceptibility locus for type 1 diabetes on Chr12q13 identified by a genome-wide association study. Diabetes. 2008;57:1143–6.
    • (2008) Diabetes , vol.57 , pp. 1143-1146
    • Hakonarson, H.1    Qu, H.Q.2    Bradfield, J.P.3
  • 14
    • 34547621758 scopus 로고    scopus 로고
    • A genome-wide association study identifies KIAA0350 as a type 1 diabetes gene
    • COI: 1:CAS:528:DC%2BD2sXosVSrt78%3D, PID: 17632545
    • Hakonarson H, Grant SF, Bradfield JP, et al. A genome-wide association study identifies KIAA0350 as a type 1 diabetes gene. Nature. 2007;448:591–4.
    • (2007) Nature , vol.448 , pp. 591-594
    • Hakonarson, H.1    Grant, S.F.2    Bradfield, J.P.3
  • 15
    • 58149090841 scopus 로고    scopus 로고
    • A human type 1 diabetes susceptibility locus maps to chromosome 21q22.3
    • COI: 1:CAS:528:DC%2BD1MXhs1KntLw%3D, PID: 18647951
    • Concannon P, Onengut-Gumuscu S, Todd JA, et al. A human type 1 diabetes susceptibility locus maps to chromosome 21q22.3. Diabetes. 2008;57:2858–61.
    • (2008) Diabetes , vol.57 , pp. 2858-2861
    • Concannon, P.1    Onengut-Gumuscu, S.2    Todd, J.A.3
  • 16
    • 56749183605 scopus 로고    scopus 로고
    • Meta-analysis of genome-wide association study data identifies additional type 1 diabetes risk loci
    • COI: 1:CAS:528:DC%2BD1cXhsVWhurvK, PID: 18978792
    • Cooper JD, Smyth DJ, Smiles AM, et al. Meta-analysis of genome-wide association study data identifies additional type 1 diabetes risk loci. Nat Genet. 2008;40:1399–401.
    • (2008) Nat Genet , vol.40 , pp. 1399-1401
    • Cooper, J.D.1    Smyth, D.J.2    Smiles, A.M.3
  • 17
    • 63249115398 scopus 로고    scopus 로고
    • Follow-up analysis of genome-wide association data identifies novel loci for type 1 diabetes
    • COI: 1:CAS:528:DC%2BD1MXptVCmsA%3D%3D, PID: 18840781
    • Grant SF, Qu HQ, Bradfield JP, et al. Follow-up analysis of genome-wide association data identifies novel loci for type 1 diabetes. Diabetes. 2009;58:290–5.
    • (2009) Diabetes , vol.58 , pp. 290-295
    • Grant, S.F.1    Qu, H.Q.2    Bradfield, J.P.3
  • 18
    • 80053439315 scopus 로고    scopus 로고
    • A genome-wide meta-analysis of six type 1 diabetes cohorts identifies multiple associated loci
    • COI: 1:CAS:528:DC%2BC3MXhtlCmtrjM, PID: 21980299
    • Bradfield JP, Qu HQ, Wang K, et al. A genome-wide meta-analysis of six type 1 diabetes cohorts identifies multiple associated loci. PLoS Genet. 2011;7:e1002293.
    • (2011) PLoS Genet , vol.7 , pp. e1002293
    • Bradfield, J.P.1    Qu, H.Q.2    Wang, K.3
  • 19
    • 67349199566 scopus 로고    scopus 로고
    • Genome-wide association study and meta-analysis find that over 40 loci affect risk of type 1 diabetes
    • COI: 1:CAS:528:DC%2BD1MXls1Cmt7c%3D, PID: 19430480
    • Barrett JC, Clayton DG, Concannon P, et al. Genome-wide association study and meta-analysis find that over 40 loci affect risk of type 1 diabetes. Nat Genet. 2009;41:703–7.
    • (2009) Nat Genet , vol.41 , pp. 703-707
    • Barrett, J.C.1    Clayton, D.G.2    Concannon, P.3
  • 20
    • 33847176604 scopus 로고    scopus 로고
    • A genome-wide association study identifies novel risk loci for type 2 diabetes
    • COI: 1:CAS:528:DC%2BD2sXhvFGiurw%3D, PID: 17293876
    • Sladek R, Rocheleau G, Rung J, et al. A genome-wide association study identifies novel risk loci for type 2 diabetes. Nature. 2007;445:881–5.
    • (2007) Nature , vol.445 , pp. 881-885
    • Sladek, R.1    Rocheleau, G.2    Rung, J.3
  • 21
    • 84969213492 scopus 로고    scopus 로고
    • Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls
    • Wellcome Trust Case Control Consortium. Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls. Nature. 2007;447:661–78.
    • (2007) Nature , vol.447 , pp. 661-678
    • Wellcome Trust Case Control Consortium1
  • 22
    • 34249888775 scopus 로고    scopus 로고
    • Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels
    • COI: 1:CAS:528:DC%2BD2sXmtVyitrk%3D, PID: 17463246
    • Saxena R, Voight BF, Lyssenko V, et al. Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels. Science. 2007;316:1331–6.
    • (2007) Science , vol.316 , pp. 1331-1336
    • Saxena, R.1    Voight, B.F.2    Lyssenko, V.3
  • 23
    • 34249895023 scopus 로고    scopus 로고
    • Replication of genome-wide association signals in UK samples reveals risk loci for type 2 diabetes
    • COI: 1:CAS:528:DC%2BD2sXmtVymtb0%3D, PID: 17463249
    • Zeggini E, Weedon MN, Lindgren CM, et al. Replication of genome-wide association signals in UK samples reveals risk loci for type 2 diabetes. Science. 2007;316:1336–41.
    • (2007) Science , vol.316 , pp. 1336-1341
    • Zeggini, E.1    Weedon, M.N.2    Lindgren, C.M.3
  • 24
    • 34249885875 scopus 로고    scopus 로고
    • A genome-wide association study of type 2 diabetes in Finns detects multiple susceptibility variants
    • COI: 1:CAS:528:DC%2BD2sXmtVyitrY%3D, PID: 17463248
    • Scott LJ, Mohlke KL, Bonnycastle LL, et al. A genome-wide association study of type 2 diabetes in Finns detects multiple susceptibility variants. Science. 2007;316:1341–5.
    • (2007) Science , vol.316 , pp. 1341-1345
    • Scott, L.J.1    Mohlke, K.L.2    Bonnycastle, L.L.3
  • 25
    • 42349106044 scopus 로고    scopus 로고
    • Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes
    • COI: 1:CAS:528:DC%2BD1cXltFylurY%3D, PID: 18372903
    • Zeggini E, Scott LJ, Saxena R, et al. Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes. Nat Genet. 2008;40:638–45.
    • (2008) Nat Genet , vol.40 , pp. 638-645
    • Zeggini, E.1    Scott, L.J.2    Saxena, R.3
  • 26
    • 34249828965 scopus 로고    scopus 로고
    • A variant in CDKAL1 influences insulin response and risk of type 2 diabetes
    • COI: 1:CAS:528:DC%2BD2sXlvVSgtL4%3D, PID: 17460697
    • Steinthorsdottir V, Thorleifsson G, Reynisdottir I, et al. A variant in CDKAL1 influences insulin response and risk of type 2 diabetes. Nat Genet. 2007;39:770–5.
    • (2007) Nat Genet , vol.39 , pp. 770-775
    • Steinthorsdottir, V.1    Thorleifsson, G.2    Reynisdottir, I.3
  • 27
    • 50449085212 scopus 로고    scopus 로고
    • SNPs in KCNQ1 are associated with susceptibility to type 2 diabetes in East Asian and European populations
    • COI: 1:CAS:528:DC%2BD1cXhtVGgt77E, PID: 18711366
    • Unoki H, Takahashi A, Kawaguchi T, et al. SNPs in KCNQ1 are associated with susceptibility to type 2 diabetes in East Asian and European populations. Nat Genet. 2008;40:1098–102.
    • (2008) Nat Genet , vol.40 , pp. 1098-1102
    • Unoki, H.1    Takahashi, A.2    Kawaguchi, T.3
  • 28
    • 50449085998 scopus 로고    scopus 로고
    • Variants in KCNQ1 are associated with susceptibility to type 2 diabetes mellitus
    • COI: 1:CAS:528:DC%2BD1cXhtVGgt77M, PID: 18711367
    • Yasuda K, Miyake K, Horikawa Y, et al. Variants in KCNQ1 are associated with susceptibility to type 2 diabetes mellitus. Nat Genet. 2008;40:1092–7.
    • (2008) Nat Genet , vol.40 , pp. 1092-1097
    • Yasuda, K.1    Miyake, K.2    Horikawa, Y.3
  • 29
    • 77954143522 scopus 로고    scopus 로고
    • Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis
    • COI: 1:CAS:528:DC%2BC3cXnvFykt70%3D, PID: 20581827
    • Voight BF, Scott LJ, Steinthorsdottir V, et al. Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis. Nat Genet. 2010;42:579–89.
    • (2010) Nat Genet , vol.42 , pp. 579-589
    • Voight, B.F.1    Scott, L.J.2    Steinthorsdottir, V.3
  • 30
    • 70349557826 scopus 로고    scopus 로고
    • Genetic variant near IRS1 is associated with type 2 diabetes, insulin resistance and hyperinsulinemia
    • COI: 1:CAS:528:DC%2BD1MXhtV2gsb%2FL, PID: 19734900
    • Rung J, Cauchi S, Albrechtsen A, et al. Genetic variant near IRS1 is associated with type 2 diabetes, insulin resistance and hyperinsulinemia. Nat Genet. 2009;41:1110–5.
    • (2009) Nat Genet , vol.41 , pp. 1110-1115
    • Rung, J.1    Cauchi, S.2    Albrechtsen, A.3
  • 31
    • 34547510624 scopus 로고    scopus 로고
    • Two variants on chromosome 17 confer prostate cancer risk, and the one in TCF2 protects against type 2 diabetes
    • COI: 1:CAS:528:DC%2BD2sXot1Cms7Y%3D, PID: 17603485
    • Gudmundsson J, Sulem P, Steinthorsdottir V, et al. Two variants on chromosome 17 confer prostate cancer risk, and the one in TCF2 protects against type 2 diabetes. Nat Genet. 2007;39:977–83.
    • (2007) Nat Genet , vol.39 , pp. 977-983
    • Gudmundsson, J.1    Sulem, P.2    Steinthorsdottir, V.3
  • 32
    • 75749086085 scopus 로고    scopus 로고
    • New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk
    • COI: 1:CAS:528:DC%2BC3cXntVCqsw%3D%3D, PID: 20081858
    • Dupuis J, Langenberg C, Prokopenko I, et al. New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk. Nat Genet. 2010;42:105–16.
    • (2010) Nat Genet , vol.42 , pp. 105-116
    • Dupuis, J.1    Langenberg, C.2    Prokopenko, I.3
  • 33
    • 34547755055 scopus 로고    scopus 로고
    • Type 2 diabetes whole-genome association study in four populations: the DiaGen Consortium
    • COI: 1:CAS:528:DC%2BD2sXptVygs74%3D, PID: 17668382
    • Salonen JT, Uimari P, Aalto JM, et al. Type 2 diabetes whole-genome association study in four populations: the DiaGen Consortium. Am J Hum Genet. 2007;81:338–45.
    • (2007) Am J Hum Genet , vol.81 , pp. 338-345
    • Salonen, J.T.1    Uimari, P.2    Aalto, J.M.3
  • 34
    • 84895868553 scopus 로고    scopus 로고
    • DIAbetes Genetics Replication And Meta-analysis (DIAGRAM) Consortium genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility. 46:234-244
    • DIAbetes Genetics Replication And Meta-analysis (DIAGRAM) Consortium genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility. Nat Genet. 46:234-244
    • Nat Genet.
  • 35
    • 84655162045 scopus 로고    scopus 로고
    • Meta-analysis of genome-wide association studies identifies eight new loci for type 2 diabetes in East Asians
    • PID: 22158537
    • Cho YS, Chen CH, Hu C, et al. Meta-analysis of genome-wide association studies identifies eight new loci for type 2 diabetes in East Asians. Nat Genet. 2011;44:67–72.
    • (2011) Nat Genet , vol.44 , pp. 67-72
    • Cho, Y.S.1    Chen, C.H.2    Hu, C.3
  • 36
    • 80053385333 scopus 로고    scopus 로고
    • Genome-wide association study in individuals of South Asian ancestry identifies six new type 2 diabetes susceptibility loci
    • COI: 1:CAS:528:DC%2BC3MXhtV2gtrfK, PID: 21874001
    • Kooner JS, Saleheen D, Sim X, et al. Genome-wide association study in individuals of South Asian ancestry identifies six new type 2 diabetes susceptibility loci. Nat Genet. 2011;43:984–9.
    • (2011) Nat Genet , vol.43 , pp. 984-989
    • Kooner, J.S.1    Saleheen, D.2    Sim, X.3
  • 37
    • 84895868553 scopus 로고    scopus 로고
    • Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility
    • DIAbetes Genetics Replication And Meta-analysis (DIAGRAM) Consortium. Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility. Nat Genet. 2014;46:234–44.
    • (2014) Nat Genet , vol.46 , pp. 234-244
    • DIAbetes Genetics Replication And Meta-analysis (DIAGRAM) Consortium1
  • 38
    • 58149175143 scopus 로고    scopus 로고
    • A variant near MTNR1B is associated with increased fasting plasma glucose levels and type 2 diabetes risk
    • COI: 1:CAS:528:DC%2BD1cXhsVKlt7zP, PID: 19060909
    • Bouatia-Naji N, Bonnefond A, Cavalcanti-Proenca C, et al. A variant near MTNR1B is associated with increased fasting plasma glucose levels and type 2 diabetes risk. Nat Genet. 2009;41:89–94.
    • (2009) Nat Genet , vol.41 , pp. 89-94
    • Bouatia-Naji, N.1    Bonnefond, A.2    Cavalcanti-Proenca, C.3
  • 39
    • 58149175669 scopus 로고    scopus 로고
    • Common variant in MTNR1B associated with increased risk of type 2 diabetes and impaired early insulin secretion
    • COI: 1:CAS:528:DC%2BD1cXhsVKlt77J, PID: 19060908
    • Lyssenko V, Nagorny CL, Erdos MR, et al. Common variant in MTNR1B associated with increased risk of type 2 diabetes and impaired early insulin secretion. Nat Genet. 2009;41:82–8.
    • (2009) Nat Genet , vol.41 , pp. 82-88
    • Lyssenko, V.1    Nagorny, C.L.2    Erdos, M.R.3
  • 40
    • 58149156287 scopus 로고    scopus 로고
    • Variants in MTNR1B influence fasting glucose levels
    • COI: 1:CAS:528:DC%2BD1cXhsVKlt7vM, PID: 19060907
    • Prokopenko I, Langenberg C, Florez JC, et al. Variants in MTNR1B influence fasting glucose levels. Nat Genet. 2009;41:77–81.
    • (2009) Nat Genet , vol.41 , pp. 77-81
    • Prokopenko, I.1    Langenberg, C.2    Florez, J.C.3
  • 41
    • 84868337361 scopus 로고    scopus 로고
    • Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes
    • COI: 1:CAS:528:DC%2BC38XhtFOgsLfP, PID: 22885922
    • Morris AP, Voight BF, Teslovich TM, et al. Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes. Nat Genet. 2012;44:981–90.
    • (2012) Nat Genet , vol.44 , pp. 981-990
    • Morris, A.P.1    Voight, B.F.2    Teslovich, T.M.3
  • 42
    • 32544451924 scopus 로고    scopus 로고
    • Variant of transcription factor 7-like 2 (TCF7L2) gene confers risk of type 2 diabetes
    • COI: 1:CAS:528:DC%2BD28XhslCjtrw%3D, PID: 16415884
    • Grant SF, Thorleifsson G, Reynisdottir I, et al. Variant of transcription factor 7-like 2 (TCF7L2) gene confers risk of type 2 diabetes. Nat Genet. 2006;38:320–3.
    • (2006) Nat Genet , vol.38 , pp. 320-323
    • Grant, S.F.1    Thorleifsson, G.2    Reynisdottir, I.3
  • 43
    • 0021343570 scopus 로고
    • A polymorphic locus near the human insulin gene is associated with insulin-dependent diabetes mellitus
    • COI: 1:CAS:528:DyaL2cXpslGktw%3D%3D, PID: 6363172
    • Bell GI, Horita S, Karam JH. A polymorphic locus near the human insulin gene is associated with insulin-dependent diabetes mellitus. Diabetes. 1984;33:176–83.
    • (1984) Diabetes , vol.33 , pp. 176-183
    • Bell, G.I.1    Horita, S.2    Karam, J.H.3
  • 44
    • 0028871202 scopus 로고
    • Susceptibility to human type 1 diabetes at IDDM2 is determined by tandem repeat variation at the insulin gene minisatellite locus
    • COI: 1:CAS:528:DyaK2MXkt1Oitrk%3D, PID: 7773291
    • Bennett ST, Lucassen AM, Gough SC, et al. Susceptibility to human type 1 diabetes at IDDM2 is determined by tandem repeat variation at the insulin gene minisatellite locus. Nat Genet. 1995;9:284–92.
    • (1995) Nat Genet , vol.9 , pp. 284-292
    • Bennett, S.T.1    Lucassen, A.M.2    Gough, S.C.3
  • 45
    • 3042698329 scopus 로고    scopus 로고
    • Remapping the insulin gene/IDDM2 locus in type 1 diabetes
    • COI: 1:CAS:528:DC%2BD2cXlslWgtbo%3D, PID: 15220214
    • Barratt BJ, Payne F, Lowe CE, et al. Remapping the insulin gene/IDDM2 locus in type 1 diabetes. Diabetes. 2004;53:1884–9.
    • (2004) Diabetes , vol.53 , pp. 1884-1889
    • Barratt, B.J.1    Payne, F.2    Lowe, C.E.3
  • 46
    • 0034139830 scopus 로고    scopus 로고
    • CTLA-4 in autoimmune diseases—a general susceptibility gene to autoimmunity?
    • COI: 1:CAS:528:DC%2BD3cXktlyhtbo%3D, PID: 11196709
    • Kristiansen OP, Larsen ZM, Pociot F. CTLA-4 in autoimmune diseases—a general susceptibility gene to autoimmunity? Genes Immun. 2000;1:170–84.
    • (2000) Genes Immun , vol.1 , pp. 170-184
    • Kristiansen, O.P.1    Larsen, Z.M.2    Pociot, F.3
  • 47
    • 0037648405 scopus 로고    scopus 로고
    • Association of the T-cell regulatory gene CTLA4 with susceptibility to autoimmune disease
    • COI: 1:CAS:528:DC%2BD3sXktVygtLk%3D, PID: 12724780
    • Ueda H, Howson JM, Esposito L, et al. Association of the T-cell regulatory gene CTLA4 with susceptibility to autoimmune disease. Nature. 2003;423:506–11.
    • (2003) Nature , vol.423 , pp. 506-511
    • Ueda, H.1    Howson, J.M.2    Esposito, L.3
  • 48
    • 10344224011 scopus 로고    scopus 로고
    • Association of the cytotoxic T lymphocyte-associated antigen 4 gene with type 1 diabetes: evidence for independent effects of two polymorphisms on the same haplotype block
    • COI: 1:CAS:528:DC%2BD2cXhtFSit73N, PID: 15579786
    • Anjos SM, Tessier MC, Polychronakos C. Association of the cytotoxic T lymphocyte-associated antigen 4 gene with type 1 diabetes: evidence for independent effects of two polymorphisms on the same haplotype block. J Clin Endocrinol Metab. 2004;89:6257–65.
    • (2004) J Clin Endocrinol Metab , vol.89 , pp. 6257-6265
    • Anjos, S.M.1    Tessier, M.C.2    Polychronakos, C.3
  • 49
    • 8944259914 scopus 로고    scopus 로고
    • The CTLA-4 gene region of chromosome 2q33 is linked to, and associated with, type 1 diabetes. Belgian Diabetes Registry
    • COI: 1:CAS:528:DyaK28Xkt1Cntb8%3D, PID: 8817351
    • Nistico L, Buzzetti R, Pritchard LE, et al. The CTLA-4 gene region of chromosome 2q33 is linked to, and associated with, type 1 diabetes. Belgian Diabetes Registry. Hum Mol Genet. 1996;5:1075–80.
    • (1996) Hum Mol Genet , vol.5 , pp. 1075-1080
    • Nistico, L.1    Buzzetti, R.2    Pritchard, L.E.3
  • 50
    • 12144291502 scopus 로고    scopus 로고
    • A functional variant of lymphoid tyrosine phosphatase is associated with type I diabetes
    • COI: 1:CAS:528:DC%2BD2cXis1ahsbw%3D, PID: 15004560
    • Bottini N, Musumeci L, Alonso A, et al. A functional variant of lymphoid tyrosine phosphatase is associated with type I diabetes. Nat Genet. 2004;36:337–8.
    • (2004) Nat Genet , vol.36 , pp. 337-338
    • Bottini, N.1    Musumeci, L.2    Alonso, A.3
  • 51
    • 7044253358 scopus 로고    scopus 로고
    • Replication of an association between the lymphoid tyrosine phosphatase locus (LYP/PTPN22) with type 1 diabetes, and evidence for its role as a general autoimmunity locus
    • COI: 1:CAS:528:DC%2BD2cXpvV2iur4%3D, PID: 15504986
    • Smyth D, Cooper JD, Collins JE, et al. Replication of an association between the lymphoid tyrosine phosphatase locus (LYP/PTPN22) with type 1 diabetes, and evidence for its role as a general autoimmunity locus. Diabetes. 2004;53:3020–3.
    • (2004) Diabetes , vol.53 , pp. 3020-3023
    • Smyth, D.1    Cooper, J.D.2    Collins, J.E.3
  • 52
    • 34548367511 scopus 로고    scopus 로고
    • Large-scale genetic fine mapping and genotype-phenotype associations implicate polymorphism in the IL2RA region in type 1 diabetes
    • COI: 1:CAS:528:DC%2BD2sXps12gtb4%3D, PID: 17676041
    • Lowe CE, Cooper JD, Brusko T, et al. Large-scale genetic fine mapping and genotype-phenotype associations implicate polymorphism in the IL2RA region in type 1 diabetes. Nat Genet. 2007;39:1074–82.
    • (2007) Nat Genet , vol.39 , pp. 1074-1082
    • Lowe, C.E.1    Cooper, J.D.2    Brusko, T.3
  • 53
    • 84855363144 scopus 로고    scopus 로고
    • Long-range DNA looping and gene expression analyses identify DEXI as an autoimmune disease candidate gene
    • COI: 1:CAS:528:DC%2BC38XmtFej, PID: 21989056
    • Davison LJ, Wallace C, Cooper JD, et al. Long-range DNA looping and gene expression analyses identify DEXI as an autoimmune disease candidate gene. Hum Mol Genet. 2012;21:322–33.
    • (2012) Hum Mol Genet , vol.21 , pp. 322-333
    • Davison, L.J.1    Wallace, C.2    Cooper, J.D.3
  • 54
    • 0033624575 scopus 로고    scopus 로고
    • The common PPARgamma Pro12Ala polymorphism is associated with decreased risk of type 2 diabetes
    • COI: 1:CAS:528:DC%2BD3cXmsVKku7k%3D, PID: 10973253
    • Altshuler D, Hirschhorn JN, Klannemark M, et al. The common PPARgamma Pro12Ala polymorphism is associated with decreased risk of type 2 diabetes. Nat Genet. 2000;26:76–80.
    • (2000) Nat Genet , vol.26 , pp. 76-80
    • Altshuler, D.1    Hirschhorn, J.N.2    Klannemark, M.3
  • 55
    • 0037317981 scopus 로고    scopus 로고
    • Large-scale association studies of variants in genes encoding the pancreatic beta-cell KATP channel subunits Kir6.2 (KCNJ11) and SUR1 (ABCC8) confirm that the KCNJ11 E23K variant is associated with type 2 diabetes
    • COI: 1:CAS:528:DC%2BD3sXhtFansbY%3D, PID: 12540637
    • Gloyn AL, Weedon MN, Owen KR, et al. Large-scale association studies of variants in genes encoding the pancreatic beta-cell KATP channel subunits Kir6.2 (KCNJ11) and SUR1 (ABCC8) confirm that the KCNJ11 E23K variant is associated with type 2 diabetes. Diabetes. 2003;52:568–72.
    • (2003) Diabetes , vol.52 , pp. 568-572
    • Gloyn, A.L.1    Weedon, M.N.2    Owen, K.R.3
  • 56
    • 34447340935 scopus 로고    scopus 로고
    • TCF7L2 is reproducibly associated with type 2 diabetes in various ethnic groups: a global meta-analysis
    • COI: 1:CAS:528:DC%2BD2sXns1yntbw%3D, PID: 17476472
    • Cauchi S, El Achhab Y, Choquet H, et al. TCF7L2 is reproducibly associated with type 2 diabetes in various ethnic groups: a global meta-analysis. J Mol Med. 2007;85:777–82.
    • (2007) J Mol Med , vol.85 , pp. 777-782
    • Cauchi, S.1    El Achhab, Y.2    Choquet, H.3
  • 57
    • 33845939675 scopus 로고    scopus 로고
    • TCF7L2: the biggest story in diabetes genetics since HLA?
    • COI: 1:STN:280:DC%2BD28jlslCisg%3D%3D, PID: 17096114
    • Zeggini E, McCarthy MI. TCF7L2: the biggest story in diabetes genetics since HLA? Diabetologia. 2007;50:1–4.
    • (2007) Diabetologia , vol.50 , pp. 1-4
    • Zeggini, E.1    McCarthy, M.I.2
  • 58
    • 34548790660 scopus 로고    scopus 로고
    • The importance of TCF7L2
    • COI: 1:CAS:528:DC%2BD2sXht1CltrrI, PID: 17888129
    • Weedon MN. The importance of TCF7L2. Diabet Med. 2007;24:1062–6.
    • (2007) Diabet Med , vol.24 , pp. 1062-1066
    • Weedon, M.N.1
  • 59
    • 34547702501 scopus 로고    scopus 로고
    • Mechanisms by which common variants in the TCF7L2 gene increase risk of type 2 diabetes
    • COI: 1:CAS:528:DC%2BD2sXoslOnsrk%3D, PID: 17671651
    • Lyssenko V, Lupi R, Marchetti P, et al. Mechanisms by which common variants in the TCF7L2 gene increase risk of type 2 diabetes. J Clin Invest. 2007;117:2155–63.
    • (2007) J Clin Invest , vol.117 , pp. 2155-2163
    • Lyssenko, V.1    Lupi, R.2    Marchetti, P.3
  • 60
    • 34547691356 scopus 로고    scopus 로고
    • Prime suspect: the TCF7L2 gene and type 2 diabetes risk
    • COI: 1:CAS:528:DC%2BD2sXoslOgu7s%3D, PID: 17671643
    • Hattersley AT. Prime suspect: the TCF7L2 gene and type 2 diabetes risk. J Clin Invest. 2007;117:2077–9.
    • (2007) J Clin Invest , vol.117 , pp. 2077-2079
    • Hattersley, A.T.1
  • 61
    • 84893716900 scopus 로고    scopus 로고
    • Sequence variants in SLC16A11 are a common risk factor for type 2 diabetes in Mexico
    • COI: 1:CAS:528:DC%2BC2cXhsl2gurY%3D, PID: 24390345
    • Williams AL, Jacobs SB, Moreno-Macias H, et al. Sequence variants in SLC16A11 are a common risk factor for type 2 diabetes in Mexico. Nature. 2014;506:97–101.
    • (2014) Nature , vol.506 , pp. 97-101
    • Williams, A.L.1    Jacobs, S.B.2    Moreno-Macias, H.3
  • 62
    • 84902185032 scopus 로고    scopus 로고
    • Association of a low-frequency variant in HNF1A with type 2 diabetes in a Latino population
    • PID: 24915262
    • Estrada K, Aukrust I, Bjorkhaug L, et al. Association of a low-frequency variant in HNF1A with type 2 diabetes in a Latino population. JAMA. 2014;311:2305–14.
    • (2014) JAMA , vol.311 , pp. 2305-2314
    • Estrada, K.1    Aukrust, I.2    Bjorkhaug, L.3
  • 63
    • 84895858002 scopus 로고    scopus 로고
    • Identification of low-frequency and rare sequence variants associated with elevated or reduced risk of type 2 diabetes
    • COI: 1:CAS:528:DC%2BC2cXht12ju7g%3D, PID: 24464100
    • Steinthorsdottir V, Thorleifsson G, Sulem P, et al. Identification of low-frequency and rare sequence variants associated with elevated or reduced risk of type 2 diabetes. Nat Genet. 2014;46:294–8.
    • (2014) Nat Genet , vol.46 , pp. 294-298
    • Steinthorsdottir, V.1    Thorleifsson, G.2    Sulem, P.3
  • 64
    • 84897407583 scopus 로고    scopus 로고
    • Loss-of-function mutations in SLC30A8 protect against type 2 diabetes
    • COI: 1:CAS:528:DC%2BC2cXjtl2jtrY%3D, PID: 24584071
    • Flannick J, Thorleifsson G, Beer NL, et al. Loss-of-function mutations in SLC30A8 protect against type 2 diabetes. Nat Genet. 2014;46:357–63.
    • (2014) Nat Genet , vol.46 , pp. 357-363
    • Flannick, J.1    Thorleifsson, G.2    Beer, N.L.3
  • 65
    • 70349956433 scopus 로고    scopus 로고
    • Finding the missing heritability of complex diseases
    • COI: 1:CAS:528:DC%2BD1MXht1CisbrF, PID: 19812666
    • Manolio TA, Collins FS, Cox NJ, et al. Finding the missing heritability of complex diseases. Nature. 2009;461:747–53.
    • (2009) Nature , vol.461 , pp. 747-753
    • Manolio, T.A.1    Collins, F.S.2    Cox, N.J.3
  • 66
    • 69949171150 scopus 로고    scopus 로고
    • No association of multiple type 2 diabetes loci with type 1 diabetes
    • COI: 1:CAS:528:DC%2BD1MXhtVygtLjF, PID: 19455305
    • Raj SM, Howson JM, Walker NM, et al. No association of multiple type 2 diabetes loci with type 1 diabetes. Diabetologia. 2009;52:2109–16.
    • (2009) Diabetologia , vol.52 , pp. 2109-2116
    • Raj, S.M.1    Howson, J.M.2    Walker, N.M.3
  • 67
    • 34548783217 scopus 로고    scopus 로고
    • The TCF7L2 locus and type 1 diabetes
    • PID: 17683561
    • Qu HQ, Polychronakos C. The TCF7L2 locus and type 1 diabetes. BMC Med Genet. 2007;8:51.
    • (2007) BMC Med Genet , vol.8 , pp. 51
    • Qu, H.Q.1    Polychronakos, C.2
  • 68
    • 33845931200 scopus 로고    scopus 로고
    • Analysis of the type 2 diabetes gene, TCF7L2, in 13,795 type 1 diabetes cases and control subjects
    • COI: 1:STN:280:DC%2BD2srmvFykug%3D%3D, PID: 17063324
    • Field SF, Howson JM, Smyth DJ, Walker NM, Dunger DB, Todd JA. Analysis of the type 2 diabetes gene, TCF7L2, in 13,795 type 1 diabetes cases and control subjects. Diabetologia. 2007;50:212–3.
    • (2007) Diabetologia , vol.50 , pp. 212-213
    • Field, S.F.1    Howson, J.M.2    Smyth, D.J.3    Walker, N.M.4    Dunger, D.B.5    Todd, J.A.6
  • 69
    • 84905569151 scopus 로고    scopus 로고
    • Andersen MK, Sterner M, Forsen T, et al. Type 2 diabetes susceptibility gene variants predispose to adult-onset autoimmune diabetes. 2014; [Epub ahead of print]
    • Andersen MK, Sterner M, Forsen T, et al. Type 2 diabetes susceptibility gene variants predispose to adult-onset autoimmune diabetes. Diabetologia. 2014; [Epub ahead of print].
    • Diabetologia.
  • 70
    • 51249110837 scopus 로고    scopus 로고
    • A genetic link between type 2 diabetes and prostate cancer
    • COI: 1:CAS:528:DC%2BD1cXhtVOnurzL, PID: 18696045
    • Frayling TM, Colhoun H, Florez JC. A genetic link between type 2 diabetes and prostate cancer. Diabetologia. 2008;51:1757–60.
    • (2008) Diabetologia , vol.51 , pp. 1757-1760
    • Frayling, T.M.1    Colhoun, H.2    Florez, J.C.3
  • 71
    • 33845963732 scopus 로고    scopus 로고
    • An association analysis of the HLA gene region in latent autoimmune diabetes in adults
    • COI: 1:CAS:528:DC%2BD2sXot1al, PID: 17143607
    • Desai M, Zeggini E, Horton VA, et al. An association analysis of the HLA gene region in latent autoimmune diabetes in adults. Diabetologia. 2007;50:68–73.
    • (2007) Diabetologia , vol.50 , pp. 68-73
    • Desai, M.1    Zeggini, E.2    Horton, V.A.3
  • 72
    • 33746761280 scopus 로고    scopus 로고
    • The variable number of tandem repeats upstream of the insulin gene is a susceptibility locus for latent autoimmune diabetes in adults
    • COI: 1:CAS:528:DC%2BD28XlsF2qs74%3D, PID: 16731859
    • Desai M, Zeggini E, Horton VA, et al. The variable number of tandem repeats upstream of the insulin gene is a susceptibility locus for latent autoimmune diabetes in adults. Diabetes. 2006;55:1890–4.
    • (2006) Diabetes , vol.55 , pp. 1890-1894
    • Desai, M.1    Zeggini, E.2    Horton, V.A.3
  • 73
    • 0032967848 scopus 로고    scopus 로고
    • Genetic heterogeneity of autoimmune diabetes: age of presentation in adults is influenced by HLA DRB1 and DQB1 genotypes (UKPDS 43). UK Prospective Diabetes Study (UKPDS) Group
    • COI: 1:CAS:528:DyaK1MXislaisLs%3D, PID: 10333055
    • Horton V, Stratton I, Bottazzo GF, et al. Genetic heterogeneity of autoimmune diabetes: age of presentation in adults is influenced by HLA DRB1 and DQB1 genotypes (UKPDS 43). UK Prospective Diabetes Study (UKPDS) Group. Diabetologia. 1999;42:608–16.
    • (1999) Diabetologia , vol.42 , pp. 608-616
    • Horton, V.1    Stratton, I.2    Bottazzo, G.F.3
  • 74
    • 0041591490 scopus 로고    scopus 로고
    • Similar genetic features and different islet cell autoantibody pattern of latent autoimmune diabetes in adults (LADA) compared with adult-onset type 1 diabetes with rapid progression
    • PID: 12547879
    • Hosszufalusi N, Vatay A, Rajczy K, et al. Similar genetic features and different islet cell autoantibody pattern of latent autoimmune diabetes in adults (LADA) compared with adult-onset type 1 diabetes with rapid progression. Diabetes Care. 2003;26:452–7.
    • (2003) Diabetes Care , vol.26 , pp. 452-457
    • Hosszufalusi, N.1    Vatay, A.2    Rajczy, K.3
  • 75
    • 0034885991 scopus 로고    scopus 로고
    • Two distinct MICA gene markers discriminate major autoimmune diabetes types
    • COI: 1:CAS:528:DC%2BD3MXlvFektbs%3D, PID: 11502807
    • Gambelunghe G, Ghaderi M, Tortoioli C, et al. Two distinct MICA gene markers discriminate major autoimmune diabetes types. J Clin Endocrinol Metab. 2001;86:3754–60.
    • (2001) J Clin Endocrinol Metab , vol.86 , pp. 3754-3760
    • Gambelunghe, G.1    Ghaderi, M.2    Tortoioli, C.3
  • 76
    • 34547285623 scopus 로고    scopus 로고
    • Genetic susceptibility to type 1 diabetes mellitus in humans
    • COI: 1:CAS:528:DC%2BD2sXotlelt7c%3D
    • Kantarova D, Buc M. Genetic susceptibility to type 1 diabetes mellitus in humans. Physiol Res Acad Sci Bohemoslovaca. 2007;56:255–66.
    • (2007) Physiol Res Acad Sci Bohemoslovaca , vol.56 , pp. 255-266
    • Kantarova, D.1    Buc, M.2
  • 77
    • 0030444451 scopus 로고    scopus 로고
    • Human type 1 diabetes and the insulin gene: principles of mapping polygenes
    • COI: 1:CAS:528:DyaK2sXht1Oi, PID: 8982458
    • Bennett ST, Todd JA. Human type 1 diabetes and the insulin gene: principles of mapping polygenes. Annu Rev Genet. 1996;30:343–70.
    • (1996) Annu Rev Genet , vol.30 , pp. 343-370
    • Bennett, S.T.1    Todd, J.A.2
  • 78
    • 48449092224 scopus 로고    scopus 로고
    • Genetic similarities between latent autoimmune diabetes in adults, type 1 diabetes, and type 2 diabetes
    • COI: 1:CAS:528:DC%2BD1cXlvVKjurs%3D, PID: 18310307
    • Cervin C, Lyssenko V, Bakhtadze E, et al. Genetic similarities between latent autoimmune diabetes in adults, type 1 diabetes, and type 2 diabetes. Diabetes. 2008;57:1433–7.
    • (2008) Diabetes , vol.57 , pp. 1433-1437
    • Cervin, C.1    Lyssenko, V.2    Bakhtadze, E.3
  • 79
    • 84856697168 scopus 로고    scopus 로고
    • The type 2 diabetes-associated variant in TCF7L2 is associated with latent autoimmune diabetes in adult Europeans and the gene effect is modified by obesity: a meta-analysis and an individual study
    • COI: 1:CAS:528:DC%2BC38Xhsl2gtrw%3D, PID: 22109281
    • Lukacs K, Hosszufalusi N, Dinya E, Bakacs M, Madacsy L, Panczel P. The type 2 diabetes-associated variant in TCF7L2 is associated with latent autoimmune diabetes in adult Europeans and the gene effect is modified by obesity: a meta-analysis and an individual study. Diabetologia. 2012;55:689–93.
    • (2012) Diabetologia , vol.55 , pp. 689-693
    • Lukacs, K.1    Hosszufalusi, N.2    Dinya, E.3    Bakacs, M.4    Madacsy, L.5    Panczel, P.6
  • 80
    • 84920906340 scopus 로고    scopus 로고
    • Szepietowska B, Moczulski D, Wawrusiewicz-Kurylonek N, Grzeszczak W, Gorska M, Szelachowska M. Transcription factor 7-like 2-gene polymorphism is related to fasting C peptide in latent autoimmune diabetes in adults (LADA). 2009; [Epub ahead of print]
    • Szepietowska B, Moczulski D, Wawrusiewicz-Kurylonek N, Grzeszczak W, Gorska M, Szelachowska M. Transcription factor 7-like 2-gene polymorphism is related to fasting C peptide in latent autoimmune diabetes in adults (LADA). Acta Diabetologica. 2009; [Epub ahead of print].
    • Acta Diabetologica.
  • 81
    • 77952703354 scopus 로고    scopus 로고
    • Association of TCF7L2 gene variants with low GAD autoantibody titre in LADA subjects (NIRAD Study 5)
    • COI: 1:CAS:528:DC%2BC3cXovFClsLg%3D
    • Zampetti S, Spoletini M, Petrone A, et al. Association of TCF7L2 gene variants with low GAD autoantibody titre in LADA subjects (NIRAD Study 5). Diabet Med J Br Diabet Assoc. 2010;27:701–4.
    • (2010) Diabet Med J Br Diabet Assoc , vol.27 , pp. 701-704
    • Zampetti, S.1    Spoletini, M.2    Petrone, A.3
  • 82
    • 55649106333 scopus 로고    scopus 로고
    • Common variants in the TCF7L2 gene help to differentiate autoimmune from non-autoimmune diabetes in young (15–34 years) but not in middle-aged (40–59 years) diabetic patients
    • COI: 1:CAS:528:DC%2BD1cXhtlCjs7%2FI, PID: 18839133
    • Bakhtadze E, Cervin C, Lindholm E, et al. Common variants in the TCF7L2 gene help to differentiate autoimmune from non-autoimmune diabetes in young (15–34 years) but not in middle-aged (40–59 years) diabetic patients. Diabetologia. 2008;51:2224–32.
    • (2008) Diabetologia , vol.51 , pp. 2224-2232
    • Bakhtadze, E.1    Cervin, C.2    Lindholm, E.3
  • 83
    • 84896491806 scopus 로고    scopus 로고
    • The many faces of diabetes: a disease with increasing heterogeneity
    • PID: 24315621
    • Tuomi T, Santoro N, Caprio S, Cai M, Weng J, Groop L. The many faces of diabetes: a disease with increasing heterogeneity. Lancet. 2014;383:1084–94.
    • (2014) Lancet , vol.383 , pp. 1084-1094
    • Tuomi, T.1    Santoro, N.2    Caprio, S.3    Cai, M.4    Weng, J.5    Groop, L.6
  • 84
    • 77953643852 scopus 로고    scopus 로고
    • Can the genetics of type 1 and type 2 diabetes shed light on the genetics of latent autoimmune diabetes in adults?
    • COI: 1:CAS:528:DC%2BC3cXmtlSgs78%3D, PID: 20007922
    • Grant SF, Hakonarson H, Schwartz S. Can the genetics of type 1 and type 2 diabetes shed light on the genetics of latent autoimmune diabetes in adults? Endocr Rev. 2010;31:183–93.
    • (2010) Endocr Rev , vol.31 , pp. 183-193
    • Grant, S.F.1    Hakonarson, H.2    Schwartz, S.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.