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Volumn 16, Issue 2, 2014, Pages 262-267

Base modification strategies to modulate immune stimulation by an siRNA

(6) Valenzuela, Rachel Anne P a Suter, Scott R a Ball Jones, Alexi A a Ibarra Soza, José M a Zheng, Yuxuan a Beal, Peter A a

a UNIVERSITY OF CALIFORNIA (United States)

Author keywords

Immune stimulation; Nucleobase modification; SiRNA; TLR8; Toll like receptors

Indexed keywords

ADENOSINE; ALPHA INTERFERON; MESSENGER RNA; NUCLEIC ACID BASE; RIBONUCLEOTIDE; SMALL INTERFERING RNA; TOLL LIKE RECEPTOR 8; TUMOR NECROSIS FACTOR ALPHA; CYTOKINE; PHOSPHATIDYLINOSITOL 3 KINASE; PIK3CB PROTEIN, HUMAN; TLR8 PROTEIN, HUMAN; TUMOR NECROSIS FACTOR;

ARTICLE; BINDING SITE; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; CRYSTAL STRUCTURE; CYCLOADDITION; CYTOKINE PRODUCTION; CYTOKINE RELEASE; DNA MODIFICATION; FEMALE; GENE SILENCING; HELA CELL LINE; HUMAN; HUMAN CELL; HYDROGEN BOND; IMMUNOSTIMULATION; MOLECULAR DOCKING; MOLECULAR MODEL; MOLECULAR RECOGNITION; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN METHYLATION; RNA BINDING; RNA INTERFERENCE; SITE DIRECTED MUTAGENESIS; SYNTHESIS; AGONISTS; ANTAGONISTS AND INHIBITORS; CHEMICAL STRUCTURE; CHEMISTRY; DRUG EFFECTS; GENETICS; IMMUNIZATION; METABOLISM; MONONUCLEAR CELL; PROCEDURES;

ADENOSINE; BINDING SITES; CYTOKINES; GENE KNOCKDOWN TECHNIQUES; HUMANS; IMMUNIZATION; LEUKOCYTES, MONONUCLEAR; MODELS, MOLECULAR; MOLECULAR DOCKING SIMULATION; PHOSPHATIDYLINOSITOL 3-KINASES; RNA INTERFERENCE; RNA, SMALL INTERFERING; TOLL-LIKE RECEPTOR 8; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84920832411 PISSN: 14394227 EISSN: 14397633 Source Type: Journal
DOI: 10.1002/cbic.201402551 Document Type: Article

Times cited : (21)

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