메뉴 건너뛰기




Volumn 15, Issue 1, 2015, Pages 79-88

Innate responses to pollen allergens

Author keywords

Allergic inflammation; aqueous pollen extract; lipid; NADPH oxidase; reactive oxygen species

Indexed keywords

INTRINSIC FACTOR; LIPID; POLLEN ANTIGEN; POLLEN EXTRACT; PROTEIN; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; TIGHT JUNCTION PROTEIN; TOLL LIKE RECEPTOR 9; OXIDOREDUCTASE; PLANT ANTIGEN;

EID: 84920829497     PISSN: 15284050     EISSN: 14736322     Source Type: Journal    
DOI: 10.1097/ACI.0000000000000136     Document Type: Review
Times cited : (47)

References (93)
  • 1
    • 0036736796 scopus 로고    scopus 로고
    • Oxidative stress in allergic respiratory diseases
    • Bowler RP, Crapo JD. Oxidative stress in allergic respiratory diseases. J Allergy Clin Immunol 2002; 110:349-356.
    • (2002) J Allergy Clin Immunol , vol.110 , pp. 349-356
    • Bowler, R.P.1    Crapo, J.D.2
  • 2
    • 59849105047 scopus 로고    scopus 로고
    • Breath markers of oxidative stress and airway inflammation in seasonal allergic rhinitis
    • Gratziou C, Rovina N, Makris M, et al. Breath markers of oxidative stress and airway inflammation in seasonal allergic rhinitis. Int J Immunopathol Pharmacol 2008; 21:949-957.
    • (2008) Int J Immunopathol Pharmacol , vol.21 , pp. 949-957
    • Gratziou, C.1    Rovina, N.2    Makris, M.3
  • 3
    • 0343920015 scopus 로고    scopus 로고
    • Rapid loss of superoxide dismutase activity during antigen-induced asthmatic response
    • Comhair SA, Bhathena PR, Dweik RA, et al. Rapid loss of superoxide dismutase activity during antigen-induced asthmatic response. Lancet 2000; 355:624.
    • (2000) Lancet , vol.355 , pp. 624
    • Comhair, S.A.1    Bhathena, P.R.2    Dweik, R.A.3
  • 4
    • 0035723661 scopus 로고    scopus 로고
    • Assessment of oxidant stress in allergic asthma by measurement of the major urinary metabolite of F2-isoprostane, 15-F2t-IsoP (8-iso-PGF2alpha)
    • Dworski R, Roberts LJ 2nd, Murray JJ, et al. Assessment of oxidant stress in allergic asthma by measurement of the major urinary metabolite of F2-isoprostane, 15-F2t-IsoP (8-iso-PGF2alpha). Clin Exp Allergy 2001; 31: 387-390.
    • (2001) Clin Exp Allergy , vol.31 , pp. 387-390
    • Dworski, R.1    Roberts, L.J.2    Murray, J.J.3
  • 5
    • 0032539920 scopus 로고    scopus 로고
    • Glutathione levels in antigen-presenting cells modulate Th1 versus Th2 response patterns
    • Peterson JD, Herzenberg LA, Vasquez K, Waltenbaugh C. Glutathione levels in antigen-presenting cells modulate Th1 versus Th2 response patterns. Proc Natl Acad Sci USA 1998; 95:3071-3076.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 3071-3076
    • Peterson, J.D.1    Herzenberg, L.A.2    Vasquez, K.3    Waltenbaugh, C.4
  • 6
    • 33746520807 scopus 로고    scopus 로고
    • Pro-oxidative diesel exhaust particle chemicals inhibit LPS-induced dendritic cell responses involved in T-helper differentiation
    • Chan RC, Wang M, Li N, et al. Pro-oxidative diesel exhaust particle chemicals inhibit LPS-induced dendritic cell responses involved in T-helper differentiation. J Allergy Clin Immunol 2006; 118:455-465.
    • (2006) J Allergy Clin Immunol , vol.118 , pp. 455-465
    • Chan, R.C.1    Wang, M.2    Li, N.3
  • 7
    • 77951936033 scopus 로고    scopus 로고
    • Pollen-induced oxidative stress influences both innate and adaptive immune responses via altering dendritic cell functions
    • Csillag A, Boldogh I, Pazmandi K, et al. Pollen-induced oxidative stress influences both innate and adaptive immune responses via altering dendritic cell functions. J Immunol 2010; 184:2377-2385.
    • (2010) J Immunol , vol.184 , pp. 2377-2385
    • Csillag, A.1    Boldogh, I.2    Pazmandi, K.3
  • 8
    • 0042834309 scopus 로고    scopus 로고
    • Generation and function of reactive oxygen species in dendritic cells during antigen presentation
    • Matsue H, Edelbaum D, Shalhevet D, et al. Generation and function of reactive oxygen species in dendritic cells during antigen presentation. J Immunol 2003; 171:3010-3018.
    • (2003) J Immunol , vol.171 , pp. 3010-3018
    • Matsue, H.1    Edelbaum, D.2    Shalhevet, D.3
  • 9
    • 23644456321 scopus 로고    scopus 로고
    • ROS generated by pollen NADPH oxidase provide a signal that augments antigen-induced allergic airway inflammation
    • Boldogh I, Bacsi A, Choudhury BK, et al. ROS generated by pollen NADPH oxidase provide a signal that augments antigen-induced allergic airway inflammation. J Clin Invest 2005; 115:2169-2179.
    • (2005) J Clin Invest , vol.115 , pp. 2169-2179
    • Boldogh, I.1    Bacsi, A.2    Choudhury, B.K.3
  • 10
    • 25844507043 scopus 로고    scopus 로고
    • Effect of pollen-mediated oxidative stress on immediate hypersensitivity reactions and late-phase inflammation in allergic conjunctivitis
    • Bacsi A, Dharajiya N, Choudhury BK, et al. Effect of pollen-mediated oxidative stress on immediate hypersensitivity reactions and late-phase inflammation in allergic conjunctivitis. J Allergy Clin Immunol 2005; 116:836-843.
    • (2005) J Allergy Clin Immunol , vol.116 , pp. 836-843
    • Bacsi, A.1    Dharajiya, N.2    Choudhury, B.K.3
  • 11
    • 33847346503 scopus 로고    scopus 로고
    • Inhibiting pollen reduced nico-tinamide adenine dinucleotide phosphate oxidase-induced signal by intrapul-monary administration of antioxidants blocks allergic airway inflammation
    • Dharajiya N, Choudhury BK, Bacsi A, et al. Inhibiting pollen reduced nico-tinamide adenine dinucleotide phosphate oxidase-induced signal by intrapul-monary administration of antioxidants blocks allergic airway inflammation. J Allergy Clin Immunol 2007; 119:646-653.
    • (2007) J Allergy Clin Immunol , vol.119 , pp. 646-653
    • Dharajiya, N.1    Choudhury, B.K.2    Bacsi, A.3
  • 12
    • 33748751668 scopus 로고    scopus 로고
    • Lactoferrin decreases pollen antigen-induced allergic airway inflammation inamurine model ofasthma
    • Kruzel ML, Bacsi A, Choudhury B, et al. Lactoferrin decreases pollen antigen-induced allergic airway inflammation inamurine model ofasthma. Immunology 2006; 119:159-166.
    • (2006) Immunology , vol.119 , pp. 159-166
    • Kruzel, M.L.1    Bacsi, A.2    Choudhury, B.3
  • 13
    • 34250639971 scopus 로고    scopus 로고
    • Iron-mediated dismutation of superoxide anion augments antigen-induced allergic inflammation: Effect of lactoferrin
    • Chodaczek G, Saavedra-Molina A, Bacsi A, et al. Iron-mediated dismutation of superoxide anion augments antigen-induced allergic inflammation: effect of lactoferrin. Postepy Hig Med Dosw (Online) 2007; 61:268-276.
    • (2007) Postepy Hig Med Dosw (Online) , vol.61 , pp. 268-276
    • Chodaczek, G.1    Saavedra-Molina, A.2    Bacsi, A.3
  • 14
    • 0026604612 scopus 로고
    • Enhanced superoxide production by alveolar macrophages and air-space cells, airway inflammation, and alveolar macrophage density changes after segmental antigen bronch-oprovocation in allergic subjects
    • Calhoun WJ, Reed HE, Moest DR, Stevens CA. Enhanced superoxide production by alveolar macrophages and air-space cells, airway inflammation, and alveolar macrophage density changes after segmental antigen bronch-oprovocation in allergic subjects. Am Rev Respir Dis 1992; 145:317-325.
    • (1992) Am Rev Respir Dis , vol.145 , pp. 317-325
    • Calhoun, W.J.1    Reed, H.E.2    Moest, D.R.3    Stevens, C.A.4
  • 15
    • 0029018265 scopus 로고
    • Spontaneous oxygen radical production at sites of antigen challenge in allergic subjects
    • Sanders SP, Zweier JL, Harrison SJ, et al. Spontaneous oxygen radical production at sites of antigen challenge in allergic subjects. Am J Respir Crit Care Med 1995; 151:1725-1733.
    • (1995) Am J Respir Crit Care Med , vol.151 , pp. 1725-1733
    • Sanders, S.P.1    Zweier, J.L.2    Harrison, S.J.3
  • 16
    • 33745425236 scopus 로고    scopus 로고
    • The course of allergen-induced leukocyte infiltration in human and experimental asthma
    • Lommatzsch M, Julius P, Kuepper M, et al. The course of allergen-induced leukocyte infiltration in human and experimental asthma. J Allergy Clin Immunol 2006; 118:91-97.
    • (2006) J Allergy Clin Immunol , vol.118 , pp. 91-97
    • Lommatzsch, M.1    Julius, P.2    Kuepper, M.3
  • 17
    • 84883483307 scopus 로고    scopus 로고
    • Deficiency of gp91phox inhibits allergic airway inflammation
    • Sevin CM, Newcomb DC, Toki S, et al. Deficiency of gp91phox inhibits allergic airway inflammation. Am J Respir Cell Mol Biol 2013; 49:396-402.
    • (2013) Am J Respir Cell Mol Biol , vol.49 , pp. 396-402
    • Sevin, C.M.1    Newcomb, D.C.2    Toki, S.3
  • 18
    • 77954105455 scopus 로고    scopus 로고
    • Mitochondrial dysfunction increases allergic airway inflammation
    • Aguilera-Aguirre L, Bacsi A, Saavedra-Molina A, et al. Mitochondrial dysfunction increases allergic airway inflammation. J Immunol 2009; 183:5379-5387.
    • (2009) J Immunol , vol.183 , pp. 5379-5387
    • Aguilera-Aguirre, L.1    Bacsi, A.2    Saavedra-Molina, A.3
  • 19
    • 67650409701 scopus 로고    scopus 로고
    • Ragweed pollen-mediated IgE-independent release of biogenic amines from mast cells via induction of mitochondrial dysfunction
    • Chodaczek G, Bacsi A, Dharajiya N, et al. Ragweed pollen-mediated IgE-independent release of biogenic amines from mast cells via induction of mitochondrial dysfunction. Mol Immunol 2009; 46:2505-2514.
    • (2009) Mol Immunol , vol.46 , pp. 2505-2514
    • Chodaczek, G.1    Bacsi, A.2    Dharajiya, N.3
  • 20
    • 0034710817 scopus 로고    scopus 로고
    • Diphenyleneiodonium prevents reactive oxygen species generation, tyrosine phosphorylation, and histamine release in RBL-2H3 mast cells
    • Matsui T, Suzuki Y, Yamashita K, et al. Diphenyleneiodonium prevents reactive oxygen species generation, tyrosine phosphorylation, and histamine release in RBL-2H3 mast cells. Biochem Biophys Res Commun 2000; 276:742-748.
    • (2000) Biochem Biophys Res Commun , vol.276 , pp. 742-748
    • Matsui, T.1    Suzuki, Y.2    Yamashita, K.3
  • 21
    • 51549106954 scopus 로고    scopus 로고
    • Mitochondrial structural changes and dysfunction are associated with experimental allergic asthma
    • Mabalirajan U, Dinda AK, Kumar S, et al. Mitochondrial structural changes and dysfunction are associated with experimental allergic asthma. J Immunol 2008; 181:3540-3548.
    • (2008) J Immunol , vol.181 , pp. 3540-3548
    • Mabalirajan, U.1    Dinda, A.K.2    Kumar, S.3
  • 22
    • 0022095076 scopus 로고
    • Ultrastructure of the bronchial epithelium in three children with asthma
    • Konradova V, Copova C, Sukova B, Houstek J. Ultrastructure of the bronchial epithelium in three children with asthma. Pediatr Pulmonol 1985; 1:182-187.
    • (1985) Pediatr Pulmonol , vol.1 , pp. 182-187
    • Konradova, V.1    Copova, C.2    Sukova, B.3    Houstek, J.4
  • 23
    • 1042265557 scopus 로고    scopus 로고
    • Ultrastructure of goblet-cell metaplasia from Clara cell in the allergic asthmatic airway inflammation in a mouse model of asthma in vivo
    • Hayashi T, Ishii A, Nakai S, Hasegawa K. Ultrastructure of goblet-cell metaplasia from Clara cell in the allergic asthmatic airway inflammation in a mouse model of asthma in vivo. Virchows Arch 2004; 444:66-73.
    • (2004) Virchows Arch , vol.444 , pp. 66-73
    • Hayashi, T.1    Ishii, A.2    Nakai, S.3    Hasegawa, K.4
  • 24
    • 84880123038 scopus 로고    scopus 로고
    • Inhaled birch pollen extract induces airway hyperresponsiveness via oxidative stress but independently of pollen-intrinsic NADPH oxidase activity, or the TLR4-TRIF pathway
    • Shalaby KH, Allard-Coutu A, O'Sullivan MJ, et al. Inhaled birch pollen extract induces airway hyperresponsiveness via oxidative stress but independently of pollen-intrinsic NADPH oxidase activity, or the TLR4-TRIF pathway. J Immunol 2013; 191:922-933.
    • (2013) J Immunol , vol.191 , pp. 922-933
    • Shalaby, K.H.1    Allard-Coutu, A.2    O'Sullivan, M.J.3
  • 25
    • 84920754266 scopus 로고    scopus 로고
    • Airway epithelial barrier function regulates the pathogenesis of allergic asthma
    • Heijink IH, Nawijn MC, Hackett TL. Airway epithelial barrier function regulates the pathogenesis of allergic asthma. Clin Exp Allergy 2014; 44:620-630.
    • (2014) Clin Exp Allergy , vol.44 , pp. 620-630
    • Heijink, I.H.1    Nawijn, M.C.2    Hackett, T.L.3
  • 26
    • 33750592575 scopus 로고    scopus 로고
    • Epithelial damage and angiogenesis in the airways of children with asthma
    • Barbato A, Turato G, Baraldo S, et al. Epithelial damage and angiogenesis in the airways of children with asthma. Am J Respir Crit Care Med 2006; 174:975-981.
    • (2006) Am J Respir Crit Care Med , vol.174 , pp. 975-981
    • Barbato, A.1    Turato, G.2    Baraldo, S.3
  • 27
    • 80052219553 scopus 로고    scopus 로고
    • Defective epithelial barrier function in asthma
    • e541-e512
    • Xiao C, Puddicombe SM, Field S, et al. Defective epithelial barrier function in asthma. J Allergy Clin Immunol 2011; 128:549-556; e541-e512.
    • (2011) J Allergy Clin Immunol , vol.128 , pp. 549-556
    • Xiao, C.1    Puddicombe, S.M.2    Field, S.3
  • 28
    • 0032695151 scopus 로고    scopus 로고
    • Der p 1 facilitates transepithelial allergen delivery by disruption of tight junctions
    • Wan H, Winton HL, Soeller C, et al. Der p 1 facilitates transepithelial allergen delivery by disruption of tight junctions. J Clin Invest 1999; 104:123-133.
    • (1999) J Clin Invest , vol.104 , pp. 123-133
    • Wan, H.1    Winton, H.L.2    Soeller, C.3
  • 29
    • 79960015037 scopus 로고    scopus 로고
    • Pollen proteases compromise the airway epithelial barrier through degradation of transmembrane adhesion proteins and lung bioactive peptides
    • Vinhas R, Cortes L, Cardoso I, et al. Pollen proteases compromise the airway epithelial barrier through degradation of transmembrane adhesion proteins and lung bioactive peptides. Allergy 2011; 66:1088-1098.
    • (2011) Allergy , vol.66 , pp. 1088-1098
    • Vinhas, R.1    Cortes, L.2    Cardoso, I.3
  • 30
    • 35748930531 scopus 로고    scopus 로고
    • Pollen proteolytic enzymes degrade tight junctions
    • Runswick S, Mitchell T, Davies P, et al. Pollen proteolytic enzymes degrade tight junctions. Respirology 2007; 12:834-842.
    • (2007) Respirology , vol.12 , pp. 834-842
    • Runswick, S.1    Mitchell, T.2    Davies, P.3
  • 31
    • 84880146024 scopus 로고    scopus 로고
    • Barrier responses of human bronchial epithelial cells to grass pollen exposure
    • Blume C, Swindle EJ, Dennison P, et al. Barrier responses of human bronchial epithelial cells to grass pollen exposure. Eur Respir J 2013; 42:87-97.
    • (2013) Eur Respir J , vol.42 , pp. 87-97
    • Blume, C.1    Swindle, E.J.2    Dennison, P.3
  • 32
    • 34250193928 scopus 로고    scopus 로고
    • Immunomodulatory mediators from pollen enhance the migratory capacity of dendritic cells and license them for Th2 attraction
    • Mariani V, Gilles S, Jakob T, et al. Immunomodulatory mediators from pollen enhance the migratory capacity of dendritic cells and license them for Th2 attraction. J Immunol 2007; 178:7623-7631.
    • (2007) J Immunol , vol.178 , pp. 7623-7631
    • Mariani, V.1    Gilles, S.2    Jakob, T.3
  • 33
    • 74049092733 scopus 로고    scopus 로고
    • Pollen-derived low-molecular weight factors inhibit 6-sulfo LacNAc+ dendritic cells' capacity to induce T-helper type 1 responses
    • Gilles S, Jacoby D, Blume C, et al. Pollen-derived low-molecular weight factors inhibit 6-sulfo LacNAc+ dendritic cells' capacity to induce T-helper type 1 responses. Clin Exp Allergy 2010; 40:269-278.
    • (2010) Clin Exp Allergy , vol.40 , pp. 269-278
    • Gilles, S.1    Jacoby, D.2    Blume, C.3
  • 34
    • 34548687998 scopus 로고    scopus 로고
    • Immunomodulatory effects of aqueous birch pollen extracts and phytoprostanes on primary immune responses in vivo
    • Gutermuth J, Bewersdorff M, Traidl-Hoffmann C, et al. Immunomodulatory effects of aqueous birch pollen extracts and phytoprostanes on primary immune responses in vivo. J Allergy Clin Immunol 2007; 120:293-299.
    • (2007) J Allergy Clin Immunol , vol.120 , pp. 293-299
    • Gutermuth, J.1    Bewersdorff, M.2    Traidl-Hoffmann, C.3
  • 35
    • 84874565816 scopus 로고    scopus 로고
    • Pollen lipidomics: Lipid profiling exposes a notable diversity in 22 allergenic pollen and potential biomarkers of the allergic immune response
    • Bashir ME, Lui JH, Palnivelu R, et al. Pollen lipidomics: lipid profiling exposes a notable diversity in 22 allergenic pollen and potential biomarkers of the allergic immune response. PLoS One 2013; 8:e57566.
    • (2013) PLoS One , vol.8 , pp. e57566
    • Bashir, M.E.1    Lui, J.H.2    Palnivelu, R.3
  • 36
    • 14244254463 scopus 로고    scopus 로고
    • Pollen-associated phyto-prostanes inhibit dendritic cell interleukin-12 production and augment T helper type 2 cell polarization
    • Traidl-Hoffmann C, Mariani V, Hochrein H, et al. Pollen-associated phyto-prostanes inhibit dendritic cell interleukin-12 production and augment T helper type 2 cell polarization. J Exp Med 2005; 201:627-636.
    • (2005) J Exp Med , vol.201 , pp. 627-636
    • Traidl-Hoffmann, C.1    Mariani, V.2    Hochrein, H.3
  • 37
    • 67449149667 scopus 로고    scopus 로고
    • Pollen-derived E1-phytoprostanes signal via PPAR-gamma and NF-kappaB-dependent mechanisms
    • Gilles S, Mariani V, Bryce M, et al. Pollen-derived E1-phytoprostanes signal via PPAR-gamma and NF-kappaB-dependent mechanisms. J Immunol 2009; 182:6653-6658.
    • (2009) J Immunol , vol.182 , pp. 6653-6658
    • Gilles, S.1    Mariani, V.2    Bryce, M.3
  • 38
    • 84876887660 scopus 로고    scopus 로고
    • Olea europaea pollen lipids activate invariant natural killer T cells by upregulating CD1d expression on dendritic cells
    • e1395
    • Abos-Gracia B, del Moral MG, Lopez-Relano J, et al. Olea europaea pollen lipids activate invariant natural killer T cells by upregulating CD1d expression on dendritic cells. J Allergy Clin Immunol 2013; 131:1393-1399; e1395.
    • (2013) J Allergy Clin Immunol , vol.131 , pp. 1393-1399
    • Abos-Gracia, B.1    Del Moral, M.G.2    Lopez-Relano, J.3
  • 39
    • 22944439737 scopus 로고    scopus 로고
    • Human CD1-restricted T cell recognition of lipids from pollens
    • Agea E, Russano A, Bistoni O, et al. Human CD1-restricted T cell recognition of lipids from pollens. J Exp Med 2005; 202:295-308.
    • (2005) J Exp Med , vol.202 , pp. 295-308
    • Agea, E.1    Russano, A.2    Bistoni, O.3
  • 40
    • 33646153985 scopus 로고    scopus 로고
    • Recognition of pollen-derived phos-phatidyl-ethanolamine by human CD1d-restricted gamma delta T cells
    • Russano AM, Agea E, Corazzi L, et al. Recognition of pollen-derived phos-phatidyl-ethanolamine by human CD1d-restricted gamma delta T cells. J Allergy Clin Immunol 2006; 117:1178-1184.
    • (2006) J Allergy Clin Immunol , vol.117 , pp. 1178-1184
    • Russano, A.M.1    Agea, E.2    Corazzi, L.3
  • 41
    • 3042788126 scopus 로고    scopus 로고
    • Chemotaxis and activation of human peripheral blood eosinophils induced by pollen-associated lipid mediators
    • Plotz SG, Traidl-Hoffmann C, Feussner I, et al. Chemotaxis and activation of human peripheral blood eosinophils induced by pollen-associated lipid mediators. J Allergy Clin Immunol 2004; 113:1152-1160.
    • (2004) J Allergy Clin Immunol , vol.113 , pp. 1152-1160
    • Plotz, S.G.1    Traidl-Hoffmann, C.2    Feussner, I.3
  • 42
    • 0036252143 scopus 로고    scopus 로고
    • Lipid mediators from pollen act as chemoattractants and activators of polymorphonuclear granulocytes
    • Traidl-Hoffmann C, Kasche A, Jakob T, et al. Lipid mediators from pollen act as chemoattractants and activators of polymorphonuclear granulocytes. J Allergy Clin Immunol 2002; 109:831-838.
    • (2002) J Allergy Clin Immunol , vol.109 , pp. 831-838
    • Traidl-Hoffmann, C.1    Kasche, A.2    Jakob, T.3
  • 43
    • 84871973839 scopus 로고    scopus 로고
    • Asthmatic airway neutrophilia after allergen challenge is associated with the glutathione S-transferase M1 genotype
    • Hoskins A, Reiss S, Wu P, et al. Asthmatic airway neutrophilia after allergen challenge is associated with the glutathione S-transferase M1 genotype. Am J Respir Crit Care Med 2013; 187:34-41.
    • (2013) Am J Respir Crit Care Med , vol.187 , pp. 34-41
    • Hoskins, A.1    Reiss, S.2    Wu, P.3
  • 44
    • 0022636068 scopus 로고
    • Bronchoalveolar lavage of allergic asthmatic patients following allergen bronchoprovocation
    • Metzger WJ, Richerson HB, Worden K, et al. Bronchoalveolar lavage of allergic asthmatic patients following allergen bronchoprovocation. Chest 1986; 89:477-483.
    • (1986) Chest , vol.89 , pp. 477-483
    • Metzger, W.J.1    Richerson, H.B.2    Worden, K.3
  • 45
    • 84856405313 scopus 로고    scopus 로고
    • Purified Timothy grass pollen major allergen Phl, p 1 may contribute to the modulation of allergic responses through a pleiotropic induction of cytokines and chemokines from airway epithelial cells
    • Roschmann KI, van Kuijen AM, Luiten S, et al. Purified Timothy grass pollen major allergen Phl p 1 may contribute to the modulation of allergic responses through a pleiotropic induction of cytokines and chemokines from airway epithelial cells. Clin Exp Immunol 2012; 167:413-421.
    • (2012) Clin Exp Immunol , vol.167 , pp. 413-421
    • Roschmann, K.I.1    Van Kuijen, A.M.2    Luiten, S.3
  • 46
    • 68349152745 scopus 로고    scopus 로고
    • Timothy grass pollen major allergen Phl p 1 activates respiratory epithelial cells by a nonprotease mechanism
    • Roschmann K, Farhat K, Konig P, et al. Timothy grass pollen major allergen Phl p 1 activates respiratory epithelial cells by a nonprotease mechanism. Clin Exp Allergy 2009; 39:1358-1369.
    • (2009) Clin Exp Allergy , vol.39 , pp. 1358-1369
    • Roschmann, K.1    Farhat, K.2    Konig, P.3
  • 47
    • 79955775978 scopus 로고    scopus 로고
    • Timothy grass pollen extract-induced gene expression and signalling pathways in airway epithelial cells
    • Roschmann KI, Luiten S, Jonker MJ, et al. Timothy grass pollen extract-induced gene expression and signalling pathways in airway epithelial cells. Clin Exp Allergy 2011; 41:830-841.
    • (2011) Clin Exp Allergy , vol.41 , pp. 830-841
    • Roschmann, K.I.1    Luiten, S.2    Jonker, M.J.3
  • 48
    • 45449106970 scopus 로고    scopus 로고
    • Effects of Parietaria judaica pollen extract on human microvascular endothelial cells
    • Taverna S, Flugy A, Colomba P, et al. Effects of Parietaria judaica pollen extract on human microvascular endothelial cells. Biochem Biophys Res Commun 2008; 372:644-649.
    • (2008) Biochem Biophys Res Commun , vol.372 , pp. 644-649
    • Taverna, S.1    Flugy, A.2    Colomba, P.3
  • 49
    • 84920849958 scopus 로고    scopus 로고
    • Ragweed pollen extract (RWPE)-induces TLR4-dependent neutrophil recruitment that augments allergic airway
    • Hosoki K, Aguilera-Aguirre L, Boldogh I, et al. Ragweed pollen extract (RWPE)-induces TLR4-dependent neutrophil recruitment that augments allergic airway. J Allergy Clin Immunol 2014; 133:AB59.
    • (2014) J Allergy Clin Immunol , vol.133 , pp. AB59
    • Hosoki, K.1    Aguilera-Aguirre, L.2    Boldogh, I.3
  • 50
    • 32044459729 scopus 로고    scopus 로고
    • Neutrophils regulate airway responses in a model of fungal allergic airways disease
    • Park SJ, Wiekowski MT, Lira SA, Mehrad B. Neutrophils regulate airway responses in a model of fungal allergic airways disease. J Immunol 2006; 176:2538-2545.
    • (2006) J Immunol , vol.176 , pp. 2538-2545
    • Park, S.J.1    Wiekowski, M.T.2    Lira, S.A.3    Mehrad, B.4
  • 51
    • 0029947548 scopus 로고    scopus 로고
    • Aerosolized human neutrophil elastase induces airway constriction and hyperresponsiveness with protection by intravenous pretreatment with half-length secretory leukoprotease inhibitor
    • Suzuki T, Wang W, Lin JT, et al. Aerosolized human neutrophil elastase induces airway constriction and hyperresponsiveness with protection by intravenous pretreatment with half-length secretory leukoprotease inhibitor. Am J Respir Crit Care Med 1996; 153:1405-1411.
    • (1996) Am J Respir Crit Care Med , vol.153 , pp. 1405-1411
    • Suzuki, T.1    Wang, W.2    Lin, J.T.3
  • 52
    • 84871388785 scopus 로고    scopus 로고
    • Epithelial-to-mesenchymal transition in pancreatic ductal adenocarcinoma and pancreatic tumor cell lines: The role of neutrophils and neutrophil-derived elastase
    • Grosse-Steffen T, Giese T, Giese N, et al. Epithelial-to-mesenchymal transition in pancreatic ductal adenocarcinoma and pancreatic tumor cell lines: the role of neutrophils and neutrophil-derived elastase. Clin Dev Immunol 2012; 2012:720768.
    • (2012) Clin Dev Immunol , vol.2012 , pp. 720768
    • Grosse-Steffen, T.1    Giese, T.2    Giese, N.3
  • 53
  • 54
    • 13644250633 scopus 로고    scopus 로고
    • Differential effects of alpha-and beta-defensin on cytokine production by cultured human bronchial epithelial cells
    • Sakamoto N, Mukae H, Fujii T, et al. Differential effects of alpha-and beta-defensin on cytokine production by cultured human bronchial epithelial cells. Am J Physiol Lung Cell Mol Physiol 2005; 288:L508-L513.
    • (2005) Am J Physiol Lung Cell Mol Physiol , vol.288 , pp. L508-L513
    • Sakamoto, N.1    Mukae, H.2    Fujii, T.3
  • 55
    • 0034541314 scopus 로고    scopus 로고
    • Peripheral blood and airway tissue expression of transforming growth factor beta by neutrophils in asthmatic subjects and normal control subjects
    • Chu HW, Trudeau JB, Balzar S, Wenzel SE. Peripheral blood and airway tissue expression of transforming growth factor beta by neutrophils in asthmatic subjects and normal control subjects. J Allergy Clin Immunol 2000; 106:1115-1123.
    • (2000) J Allergy Clin Immunol , vol.106 , pp. 1115-1123
    • Chu, H.W.1    Trudeau, J.B.2    Balzar, S.3    Wenzel, S.E.4
  • 56
    • 0032213375 scopus 로고    scopus 로고
    • Inside the neutrophil phagosome: Oxidants, myeloperoxidase, and bacterial killing
    • Hampton MB, Kettle AJ, Winterbourn CC. Inside the neutrophil phagosome: oxidants, myeloperoxidase, and bacterial killing. Blood 1998; 92:3007-3017.
    • (1998) Blood , vol.92 , pp. 3007-3017
    • Hampton, M.B.1    Kettle, A.J.2    Winterbourn, C.C.3
  • 57
    • 82555191081 scopus 로고    scopus 로고
    • Short ragweed pollen triggers allergic inflammation through Toll-like receptor 4-dependent thymic stromal lympho-poietin/OX40 ligand/OX40 signaling pathways
    • e1312
    • Li DQ, Zhang L, Pflugfelder SC, et al. Short ragweed pollen triggers allergic inflammation through Toll-like receptor 4-dependent thymic stromal lympho-poietin/OX40 ligand/OX40 signaling pathways. J Allergy Clin Immunol 2011; 128:1318-1325; e1312.
    • (2011) J Allergy Clin Immunol , vol.128 , pp. 1318-1325
    • Li, D.Q.1    Zhang, L.2    Pflugfelder, S.C.3
  • 58
    • 77950296865 scopus 로고    scopus 로고
    • Thymic stromal lymphopoietin-induced human asthmatic airway epithelial cell proliferation through an IL-13-depen-dent pathway
    • Semlali A, Jacques E, Koussih L, et al. Thymic stromal lymphopoietin-induced human asthmatic airway epithelial cell proliferation through an IL-13-depen-dent pathway. J Allergy Clin Immunol 2010; 125:844-850.
    • (2010) J Allergy Clin Immunol , vol.125 , pp. 844-850
    • Semlali, A.1    Jacques, E.2    Koussih, L.3
  • 59
    • 25844515028 scopus 로고    scopus 로고
    • Thymic stromal lymphopoietin as a key initiator of allergic airway inflammation in mice
    • Zhou B, Comeau MR, De Smedt T, et al. Thymic stromal lymphopoietin as a key initiator of allergic airway inflammation in mice. Nat Immunol 2005; 6:1047-1053.
    • (2005) Nat Immunol , vol.6 , pp. 1047-1053
    • Zhou, B.1    Comeau, M.R.2    De Smedt, T.3
  • 60
    • 84883228759 scopus 로고    scopus 로고
    • Novel allergic asthma model demonstrates ST2-dependent dendritic cell targeting by cypress pollen
    • e687
    • Gabriele L, Schiavoni G, Mattei F, et al. Novel allergic asthma model demonstrates ST2-dependent dendritic cell targeting by cypress pollen. J Allergy Clin Immunol 2013; 132:686-695; e687.
    • (2013) J Allergy Clin Immunol , vol.132 , pp. 686-695
    • Gabriele, L.1    Schiavoni, G.2    Mattei, F.3
  • 61
    • 84856497926 scopus 로고    scopus 로고
    • The role of IL-33 and its receptor ST2 in human nasal epithelium with allergic rhinitis
    • Kamekura R, Kojima T, Takano K, et al. The role of IL-33 and its receptor ST2 in human nasal epithelium with allergic rhinitis. Clin Exp Allergy 2012; 42:218-228.
    • (2012) Clin Exp Allergy , vol.42 , pp. 218-228
    • Kamekura, R.1    Kojima, T.2    Takano, K.3
  • 62
    • 27744446058 scopus 로고    scopus 로고
    • IL-33, an interleukin-1-like cytokine that signals via the IL-1 receptor-related protein ST2 and induces T helper type 2-associated cytokines
    • Schmitz J, Owyang A, Oldham E, et al. IL-33, an interleukin-1-like cytokine that signals via the IL-1 receptor-related protein ST2 and induces T helper type 2-associated cytokines. Immunity 2005; 23:479-490.
    • (2005) Immunity , vol.23 , pp. 479-490
    • Schmitz, J.1    Owyang, A.2    Oldham, E.3
  • 63
    • 75549085516 scopus 로고    scopus 로고
    • IL-33 amplifies the polarization of alternatively activated macrophages that contribute to airway inflammation
    • Kurowska-Stolarska M, Stolarski B, Kewin P, et al. IL-33 amplifies the polarization of alternatively activated macrophages that contribute to airway inflammation. J Immunol 2009; 183:6469-6477.
    • (2009) J Immunol , vol.183 , pp. 6469-6477
    • Kurowska-Stolarska, M.1    Stolarski, B.2    Kewin, P.3
  • 64
    • 84884905739 scopus 로고    scopus 로고
    • IL-33 is more potent than IL-25 in provoking IL-13-producing nuocytes (type 2 innate lymphoid cells) and airway contraction
    • Barlow JL, Peel S, Fox J, et al. IL-33 is more potent than IL-25 in provoking IL-13-producing nuocytes (type 2 innate lymphoid cells) and airway contraction. J Allergy Clin Immunol 2013; 132:933-941.
    • (2013) J Allergy Clin Immunol , vol.132 , pp. 933-941
    • Barlow, J.L.1    Peel, S.2    Fox, J.3
  • 65
    • 77956624172 scopus 로고    scopus 로고
    • Nuclear erythroid 2 p45-related factor 2 inhibits the maturation of murine dendritic cells by ragweed extract
    • Rangasamy T, Williams MA, Bauer S, et al. Nuclear erythroid 2 p45-related factor 2 inhibits the maturation of murine dendritic cells by ragweed extract. Am J Respir Cell Mol Biol 2010; 43:276-285.
    • (2010) Am J Respir Cell Mol Biol , vol.43 , pp. 276-285
    • Rangasamy, T.1    Williams, M.A.2    Bauer, S.3
  • 66
    • 76249102285 scopus 로고    scopus 로고
    • Cupressaceae pollen grains modulate dendritic cell response and exhibit IgE-inducing adjuvant activity in vivo
    • Kamijo S, Takai T, Kuhara T, et al. Cupressaceae pollen grains modulate dendritic cell response and exhibit IgE-inducing adjuvant activity in vivo. J Immunol 2009; 183:6087-6094.
    • (2009) J Immunol , vol.183 , pp. 6087-6094
    • Kamijo, S.1    Takai, T.2    Kuhara, T.3
  • 67
    • 0033933006 scopus 로고    scopus 로고
    • Langerhans-like dendritic cells generated from cord blood progenitors internalize pollen allergens by macropinocytosis, and part of the molecules are processed and can activate autologous naive T lymphocytes
    • Noirey N, Rougier N, Andre C, et al. Langerhans-like dendritic cells generated from cord blood progenitors internalize pollen allergens by macropinocytosis, and part of the molecules are processed and can activate autologous naive T lymphocytes. J Allergy Clin Immunol 2000; 105:1194-1201.
    • (2000) J Allergy Clin Immunol , vol.105 , pp. 1194-1201
    • Noirey, N.1    Rougier, N.2    Andre, C.3
  • 68
    • 0043031387 scopus 로고    scopus 로고
    • Heinrich J: TLR4 gene variants modify endotoxin effects on asthma
    • Werner M, Topp R, Wimmer K, et al. Heinrich J: TLR4 gene variants modify endotoxin effects on asthma. J Allergy Clin Immunol 2003; 112: 323-330.
    • (2003) J Allergy Clin Immunol , vol.112 , pp. 323-330
    • Werner, M.1    Topp, R.2    Wimmer, K.3
  • 69
    • 73549100656 scopus 로고    scopus 로고
    • TLR-related pathway analysis: Novel gene-gene interactions in the development of asthma and atopy
    • Reijmerink NE, Bottema RW, Kerkhof M, et al. TLR-related pathway analysis: novel gene-gene interactions in the development of asthma and atopy. Allergy 2010; 65:199-207.
    • (2010) Allergy , vol.65 , pp. 199-207
    • Reijmerink, N.E.1    Bottema, R.W.2    Kerkhof, M.3
  • 70
    • 84881169378 scopus 로고    scopus 로고
    • Childhood allergic rhinitis, traffic-related air pollution, and variability in the GSTP1, TNF, TLR2, and TLR4 genes: Results from the TAG Study
    • e342
    • Fuertes E, Brauer M, MacIntyre E, et al. Childhood allergic rhinitis, traffic-related air pollution, and variability in the GSTP1, TNF, TLR2, and TLR4 genes: results from the TAG Study. J Allergy Clin Immunol 2013; 132:342-352; e342.
    • (2013) J Allergy Clin Immunol , vol.132 , pp. 342-352
    • Fuertes, E.1    Brauer, M.2    Macintyre, E.3
  • 71
    • 77956050465 scopus 로고    scopus 로고
    • Toll-like receptor 2 and 4 genes influence susceptibility to adverse effects of traffic-related air pollution on childhood asthma
    • Kerkhof M, Postma DS, Brunekreef B, et al. Toll-like receptor 2 and 4 genes influence susceptibility to adverse effects of traffic-related air pollution on childhood asthma. Thorax 2010; 65:690-697.
    • (2010) Thorax , vol.65 , pp. 690-697
    • Kerkhof, M.1    Postma, D.S.2    Brunekreef, B.3
  • 72
    • 78649430294 scopus 로고    scopus 로고
    • Children with atopic histories exhibit impaired lipopolysaccharide-induced Toll-like receptor-4 signalling in peripheral monocytes
    • Prefontaine D, Banville-Langelier AA, Fiset PO, et al. Children with atopic histories exhibit impaired lipopolysaccharide-induced Toll-like receptor-4 signalling in peripheral monocytes. Clin Exp Allergy 2010; 40:1648-1657.
    • (2010) Clin Exp Allergy , vol.40 , pp. 1648-1657
    • Prefontaine, D.1    Banville-Langelier, A.A.2    Fiset, P.O.3
  • 73
    • 0038448226 scopus 로고    scopus 로고
    • Bacterial lipopolysaccharide signaling through Toll-like receptor 4 suppresses asthma-like responses via nitric oxide synthase 2 activity
    • Rodriguez D, Keller AC, Faquim-Mauro EL, et al. Bacterial lipopolysaccharide signaling through Toll-like receptor 4 suppresses asthma-like responses via nitric oxide synthase 2 activity. J Immunol 2003; 171:1001-1008.
    • (2003) J Immunol , vol.171 , pp. 1001-1008
    • Rodriguez, D.1    Keller, A.C.2    Faquim-Mauro, E.L.3
  • 74
    • 77951643500 scopus 로고    scopus 로고
    • TLR4 signaling in stromal cells is critical for the initiation of allergic Th2 responses to inhaled antigen
    • Tan AM, Chen HC, Pochard P, et al. TLR4 signaling in stromal cells is critical for the initiation of allergic Th2 responses to inhaled antigen. J Immunol 2010; 184:3535-3544.
    • (2010) J Immunol , vol.184 , pp. 3535-3544
    • Tan, A.M.1    Chen, H.C.2    Pochard, P.3
  • 75
    • 0037121946 scopus 로고    scopus 로고
    • Lipopolysaccharide-enhanced, toll-like receptor 4-dependent T helper cell type 2 responses to inhaled antigen
    • Eisenbarth SC, Piggott DA, Huleatt JW, et al. Lipopolysaccharide-enhanced, toll-like receptor 4-dependent T helper cell type 2 responses to inhaled antigen. J Exp Med 2002; 196:1645-1651.
    • (2002) J Exp Med , vol.196 , pp. 1645-1651
    • Eisenbarth, S.C.1    Piggott, D.A.2    Huleatt, J.W.3
  • 76
    • 64149087970 scopus 로고    scopus 로고
    • House dust mite allergen induces asthma via Toll-like receptor 4 triggering of airway structural cells
    • Hammad H, Chieppa M, Perros F, et al. House dust mite allergen induces asthma via Toll-like receptor 4 triggering of airway structural cells. Nat Med 2009; 15:410-416.
    • (2009) Nat Med , vol.15 , pp. 410-416
    • Hammad, H.1    Chieppa, M.2    Perros, F.3
  • 77
    • 59049100417 scopus 로고    scopus 로고
    • Allergenicity resulting from functional mimicry of a Toll-like receptor complex protein
    • Trompette A, Divanovic S, Visintin A, et al. Allergenicity resulting from functional mimicry of a Toll-like receptor complex protein. Nature 2009; 457:585-588.
    • (2009) Nature , vol.457 , pp. 585-588
    • Trompette, A.1    Divanovic, S.2    Visintin, A.3
  • 78
    • 84866170168 scopus 로고    scopus 로고
    • ICOS-expressing CD4 T cells induced via TLR4 in the nasal mucosa are capable of inhibiting experimental allergic asthma
    • Shalaby KH, Jo T, Nakada E, et al. ICOS-expressing CD4 T cells induced via TLR4 in the nasal mucosa are capable of inhibiting experimental allergic asthma. J Immunol 2012; 189:2793-2804.
    • (2012) J Immunol , vol.189 , pp. 2793-2804
    • Shalaby, K.H.1    Jo, T.2    Nakada, E.3
  • 79
    • 84875000381 scopus 로고    scopus 로고
    • TLR ligands of ryegrass pollen microbial contaminants enhance Th1 and Th2 responses and decrease induction of Foxp3(hi) regulatory T cells
    • Mittag D, Varese N, Scholzen A, et al. TLR ligands of ryegrass pollen microbial contaminants enhance Th1 and Th2 responses and decrease induction of Foxp3(hi) regulatory T cells. Eur J Immunol 2013; 43:723-733.
    • (2013) Eur J Immunol , vol.43 , pp. 723-733
    • Mittag, D.1    Varese, N.2    Scholzen, A.3
  • 80
    • 84873715844 scopus 로고    scopus 로고
    • The major allergen of the Parietaria pollen contains an LPS-binding region with immuno-modulatory activity
    • Bonura A, Corinti S, Schiavi E, et al. The major allergen of the Parietaria pollen contains an LPS-binding region with immuno-modulatory activity. Allergy 2013; 68:297-303.
    • (2013) Allergy , vol.68 , pp. 297-303
    • Bonura, A.1    Corinti, S.2    Schiavi, E.3
  • 81
    • 77950878748 scopus 로고    scopus 로고
    • Functional interaction of common allergens and a C-type lectin receptor, dendritic cell-specific ICAM3-grabbing nonintegrin (DC-SIGN), on human dendritic cells
    • Hsu SC, Chen CH, Tsai SH, et al. Functional interaction of common allergens and a C-type lectin receptor, dendritic cell-specific ICAM3-grabbing nonintegrin (DC-SIGN), on human dendritic cells. J Biol Chem 2010; 285:7903-7910.
    • (2010) J Biol Chem , vol.285 , pp. 7903-7910
    • Hsu, S.C.1    Chen, C.H.2    Tsai, S.H.3
  • 82
    • 0034176816 scopus 로고    scopus 로고
    • Alveolar macrophages bind and phagocytose allergen-containing pollen starch granules via C-type lectin and integrin receptors: Implications for airway inflammatory disease
    • Currie AJ, Stewart GA, McWilliam AS. Alveolar macrophages bind and phagocytose allergen-containing pollen starch granules via C-type lectin and integrin receptors: implications for airway inflammatory disease. J Immunol 2000; 164:3878-3886.
    • (2000) J Immunol , vol.164 , pp. 3878-3886
    • Currie, A.J.1    Stewart, G.A.2    McWilliam, A.S.3
  • 83
    • 33749436870 scopus 로고    scopus 로고
    • Immunotherapy with a ragweed-toll-like receptor 9 agonist vaccine for allergic rhinitis
    • Creticos PS, Schroeder JT, Hamilton RG, et al. Immunotherapy with a ragweed-toll-like receptor 9 agonist vaccine for allergic rhinitis. N Engl J Med 2006; 355:1445-1455.
    • (2006) N Engl J Med , vol.355 , pp. 1445-1455
    • Creticos, P.S.1    Schroeder, J.T.2    Hamilton, R.G.3
  • 84
    • 3042718066 scopus 로고    scopus 로고
    • Selective immune redirection in humans with ragweed allergy by injecting Amb a 1 linked to immunostimu-latory DNA
    • Simons FE, Shikishima Y, Van Nest G, et al. Selective immune redirection in humans with ragweed allergy by injecting Amb a 1 linked to immunostimu-latory DNA. J Allergy Clin Immunol 2004; 113:1144-1151.
    • (2004) J Allergy Clin Immunol , vol.113 , pp. 1144-1151
    • Simons, F.E.1    Shikishima, Y.2    Van Nest, G.3
  • 85
    • 1142273128 scopus 로고    scopus 로고
    • Amb a 1-immunostimulatory oligodeoxynucleotide conjugate immunotherapy decreases the nasal inflammatory response
    • Tulic MK, Fiset PO, Christodoulopoulos P, et al. Amb a 1-immunostimulatory oligodeoxynucleotide conjugate immunotherapy decreases the nasal inflammatory response. J Allergy Clin Immunol 2004; 113:235-241.
    • (2004) J Allergy Clin Immunol , vol.113 , pp. 235-241
    • Tulic, M.K.1    Fiset, P.O.2    Christodoulopoulos, P.3
  • 86
    • 70149112819 scopus 로고    scopus 로고
    • Allergen-specific immunotherapy of allergy and asthma: Current and future trends
    • Spertini F, Reymond C, Leimgruber A. Allergen-specific immunotherapy of allergy and asthma: current and future trends. Expert Rev Respir Med 2009; 3:37-51.
    • (2009) Expert Rev Respir Med , vol.3 , pp. 37-51
    • Spertini, F.1    Reymond, C.2    Leimgruber, A.3
  • 87
    • 84879933837 scopus 로고    scopus 로고
    • Pollinex Quattro: An innovative four injections immunotherapy in allergic rhinitis
    • Rosewich M, Lee D, Zielen S. Pollinex Quattro: an innovative four injections immunotherapy in allergic rhinitis. Hum Vaccin Immunother 2013; 9:1523-1531.
    • (2013) Hum Vaccin Immunother , vol.9 , pp. 1523-1531
    • Rosewich, M.1    Lee, D.2    Zielen, S.3
  • 88
    • 84899977538 scopus 로고    scopus 로고
    • Phase I/II study of oral im-munotherapy with Cry j1-galactomannan conjugate for Japanese cedar pollinosis
    • Murakami D, Kubo K, Sawatsubashi M, et al. Phase I/II study of oral im-munotherapy with Cry j1-galactomannan conjugate for Japanese cedar pollinosis. Auris Nasus Larynx 2014; 41:350-358.
    • (2014) Auris Nasus Larynx , vol.41 , pp. 350-358
    • Murakami, D.1    Kubo, K.2    Sawatsubashi, M.3
  • 89
    • 6844266292 scopus 로고    scopus 로고
    • Bet v 1, the major birch pollen allergen, conjugated to crystalline bacterial cell surface proteins, expands allergen-specific T cells of the Th1/Th0 phenotype in vitro by induction of IL-12
    • Jahn-Schmid B, Siemann U, Zenker A, et al. Bet v 1, the major birch pollen allergen, conjugated to crystalline bacterial cell surface proteins, expands allergen-specific T cells of the Th1/Th0 phenotype in vitro by induction of IL-12. Int Immunol 1997; 9:1867-1874.
    • (1997) Int Immunol , vol.9 , pp. 1867-1874
    • Jahn-Schmid, B.1    Siemann, U.2    Zenker, A.3
  • 90
    • 34547137168 scopus 로고    scopus 로고
    • Allergy multivaccines created by DNA shuffling of tree pollen allergens
    • Wallner M, Stocklinger A, Thalhamer T, et al. Allergy multivaccines created by DNA shuffling of tree pollen allergens. J Allergy Clin Immunol 2007; 120:374-380.
    • (2007) J Allergy Clin Immunol , vol.120 , pp. 374-380
    • Wallner, M.1    Stocklinger, A.2    Thalhamer, T.3
  • 91
    • 84861665330 scopus 로고    scopus 로고
    • Superparamagnetic iron oxide nanoparticles conjugated to a grass pollen allergen and an optical probe
    • Herranz F, Schmidt-Weber CB, Shamji MH, et al. Superparamagnetic iron oxide nanoparticles conjugated to a grass pollen allergen and an optical probe. Contrast Media Mol Imaging 2012; 7:435-439.
    • (2012) Contrast Media Mol Imaging , vol.7 , pp. 435-439
    • Herranz, F.1    Schmidt-Weber, C.B.2    Shamji, M.H.3
  • 92
    • 84905216421 scopus 로고    scopus 로고
    • DNA aptamers against the Cry j 2 allergen of Japanese cedar pollen for biosensing applications
    • Ogihara K, Savory N, Abe K, et al. DNA aptamers against the Cry j 2 allergen of Japanese cedar pollen for biosensing applications. Biosens Bioelectron 2015; 63:159-165.
    • (2015) Biosens Bioelectron , vol.63 , pp. 159-165
    • Ogihara, K.1    Savory, N.2    Abe, K.3
  • 93
    • 84862519263 scopus 로고    scopus 로고
    • Safety and efficacy of a CXCR2 antagonist in patients with severe asthma and sputum neutrophils: A randomized, placebo-controlled clinical trial
    • Nair P, Gaga M, Zervas E, et al. Safety and efficacy of a CXCR2 antagonist in patients with severe asthma and sputum neutrophils: a randomized, placebo-controlled clinical trial. Clin Exp Allergy 2012; 42:1097-1103.
    • (2012) Clin Exp Allergy , vol.42 , pp. 1097-1103
    • Nair, P.1    Gaga, M.2    Zervas, E.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.