Mito-protective autophagy is impaired in erythroid cells of aged mtDNA-mutator mice

Blood

Volumn 125, Issue 1, 2015, Pages 162-174

  Li Harms, XiuJie ^a   Milasta, Sandra ^a   Lynch, John ^a   Wright, Christopher ^a   Joshi, Aashish ^a   Iyengar, Rekha ^a   Neale, Geoffrey ^a   Wang, Xi ^a   Wang, Yong Dong ^a   Prolla, Tomas A ^b   Thompson, James E ^c   Opferman, Joseph T ^a   Green, Douglas R ^a   Schuetz, John ^a   Kundu, Mondira ^a  

^a ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

^b UNIVERSITY OF WISCONSIN MADISON   (United States)

^c ROSWELL PARK CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DNA POLYMERASE; MAMMALIAN TARGET OF RAPAMYCIN; MITOCHONDRIAL DNA; PROTEIN SERINE THREONINE KINASE; UNCLASSIFIED DRUG; UNCOORDINATED 51 LIKE KINASE 1; DNA DIRECTED DNA POLYMERASE; MTOR PROTEIN, MOUSE; POLG PROTEIN, MOUSE; PROTEASOME; TARGET OF RAPAMYCIN KINASE;

ANIMAL CELL; ARTICLE; AUTOPHAGY; CELL MATURATION; CONTROLLED STUDY; DISEASE COURSE; DISORDERS OF MITOCHONDRIAL FUNCTIONS; ENZYME ACTIVATION; ERYTHROID CELL; ERYTHROID PRECURSOR CELL; GENE DISRUPTION; GENE MUTATION; HEMATOPOIETIC CELL; IN VIVO STUDY; MACROCYTIC ANEMIA; MITOCHONDRIAL RESPIRATION; MITOCHONDRION; MOUSE; NONHUMAN; OXIDATIVE PHOSPHORYLATION; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RIBOSOME; SIGNAL TRANSDUCTION; AGING; ANEMIA; ANIMAL; CELL SEPARATION; CYTOLOGY; ERYTHROCYTE; FLOW CYTOMETRY; GENETICS; HETEROZYGOTE; METABOLISM; MUTATION; MYELODYSPLASTIC SYNDROME; OXYGEN CONSUMPTION; PHENOTYPE; PHOSPHORYLATION;

AGING; ANEMIA; ANIMALS; AUTOPHAGY; CELL SEPARATION; DNA, MITOCHONDRIAL; DNA-DIRECTED DNA POLYMERASE; ERYTHROCYTES; ERYTHROID CELLS; FLOW CYTOMETRY; HETEROZYGOTE; MICE; MITOCHONDRIA; MUTATION; MYELODYSPLASTIC SYNDROMES; OXYGEN CONSUMPTION; PHENOTYPE; PHOSPHORYLATION; PROTEASOME ENDOPEPTIDASE COMPLEX; RIBOSOMES; TOR SERINE-THREONINE KINASES;

EID: 84920624510     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2014-07-586396     Document Type: Article

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