-
1
-
-
0035955628
-
De novo synthesis of RNA by the dengue virus RNA-dependent RNA polymerase exhibits temperature dependence at the initiation but not elongation phase
-
Ackermann, M., and Padmanabhan, R. (2001). De novo synthesis of RNA by the dengue virus RNA-dependent RNA polymerase exhibits temperature dependence at the initiation but not elongation phase. J Biol Chem 276, 39926-39937.
-
(2001)
J Biol Chem
, vol.276
, pp. 39926-39937
-
-
Ackermann, M.1
Padmanabhan, R.2
-
2
-
-
0033571463
-
Crystal structure of the RNA-dependent RNA polymerase of hepatitis C virus
-
Ago, H., Adachi, T., Yoshida, A., Yamamoto, M., Habuka, N., Yatsunami, K., and Miyano, M. (1999). Crystal structure of the RNA-dependent RNA polymerase of hepatitis C virus. Structure 7, 1417-1426.
-
(1999)
Structure
, vol.7
, pp. 1417-1426
-
-
Ago, H.1
Adachi, T.2
Yoshida, A.3
Yamamoto, M.4
Habuka, N.5
Yatsunami, K.6
Miyano, M.7
-
3
-
-
0033773926
-
The hepatitis C virus NS5B RNA-dependent RNA polymerase activity and susceptibility to inhibitors is modulated by metal cations
-
Alaoui-Lsmaili, M. H., Hamel, M., L'Heureux, L., Nicolas, O., Bilimoria, D., Labonte, P., Mounir, S., and Rando, R. F. (2000). The hepatitis C virus NS5B RNA-dependent RNA polymerase activity and susceptibility to inhibitors is modulated by metal cations. J Hum Virol 3, 306-316.
-
(2000)
J Hum Virol
, vol.3
, pp. 306-316
-
-
Alaoui-Lsmaili, M.H.1
Hamel, M.2
L'Heureux, L.3
Nicolas, O.4
Bilimoria, D.5
Labonte, P.6
Mounir, S.7
Rando, R.F.8
-
4
-
-
10644250663
-
Crystal structure of complete rhinovirus RNA polymerase suggests front loading of protein primer
-
Appleby, T. C., Luecke, H., Shim, J. H., Wu, J. Z., Cheney, I.W., Zhong, W., Vogeley, L., Hong, Z., and Yao, N. (2005). Crystal structure of complete rhinovirus RNA polymerase suggests front loading of protein primer. J Virol 79, 277-288.
-
(2005)
J Virol
, vol.79
, pp. 277-288
-
-
Appleby, T.C.1
Luecke, H.2
Shim, J.H.3
Wu, J.Z.4
Cheney, I.W.5
Zhong, W.6
Vogeley, L.7
Hong, Z.8
Yao, N.9
-
5
-
-
27144462037
-
Mutant viral polymerase in the transition of virus to error catastrophe identifies a critical site for RNA binding
-
Arias, A., Agudo, R., Ferrer-Orta, C., Perez-Luque, R., Airaksinen, A., Brocchi, E., Domingo, E., Verdaguer, N., and Escarmis, C. (2005). Mutant viral polymerase in the transition of virus to error catastrophe identifies a critical site for RNA binding. J Mol Biol 353, 1021-1032.
-
(2005)
J Mol Biol
, vol.353
, pp. 1021-1032
-
-
Arias, A.1
Agudo, R.2
Ferrer-Orta, C.3
Perez-Luque, R.4
Airaksinen, A.5
Brocchi, E.6
Domingo, E.7
Verdaguer, N.8
Escarmis, C.9
-
6
-
-
0034090927
-
Poliovirus RNA-dependent RNA polymerase (3D(pol)). Assembly of stable, elongation-competent complexes by using a symmetrical primer-template substrate (sym/sub)
-
Arnold, J. J., and Cameron, C. E. (2000). Poliovirus RNA-dependent RNA polymerase (3D(pol)). Assembly of stable, elongation-competent complexes by using a symmetrical primer-template substrate (sym/sub). J Biol Chem 275, 5329-5336.
-
(2000)
J Biol Chem
, vol.275
, pp. 5329-5336
-
-
Arnold, J.J.1
Cameron, C.E.2
-
7
-
-
2442584664
-
Poliovirus RNA-dependent RNA polymerase (3Dpol): Pre-steady-state kinetic analysis of ribonucleotide incorporation in the presence of Mg2
-
Arnold, J. J., and Cameron, C. E. (2004). Poliovirus RNA-dependent RNA polymerase (3Dpol): Pre-steady-state kinetic analysis of ribonucleotide incorporation in the presence of Mg2+. Biochemistry 43, 5126-5137.
-
(2004)
Biochemistry
, vol.43
, pp. 5126-5137
-
-
Arnold, J.J.1
Cameron, C.E.2
-
8
-
-
0033601209
-
Poliovirus RNA-dependent RNA polymerase (3D(pol)). Divalent cation modulation of primer, template, and nucleotide selection
-
Arnold, J. J., Ghosh, S. K., and Cameron, C. E. (1999). Poliovirus RNA-dependent RNA polymerase (3D(pol)). Divalent cation modulation of primer, template, and nucleotide selection. J Biol Chem 274, 37060-37069.
-
(1999)
J Biol Chem
, vol.274
, pp. 37060-37069
-
-
Arnold, J.J.1
Ghosh, S.K.2
Cameron, C.E.3
-
9
-
-
2442498536
-
Poliovirus RNA-dependent RNA polymerase (3Dpol): Pre-steady-state kinetic analysis of ribonucleotide incorporation in the presence of Mn2
-
Arnold, J. J., Gohara, D. W., and Cameron, C. E. (2004). Poliovirus RNA-dependent RNA polymerase (3Dpol): Pre-steady-state kinetic analysis of ribonucleotide incorporation in the presence of Mn2+. Biochemistry 43, 5138-5148.
-
(2004)
Biochemistry
, vol.43
, pp. 5138-5148
-
-
Arnold, J.J.1
Gohara, D.W.2
Cameron, C.E.3
-
10
-
-
0022348809
-
On the fidelity of DNA replication: Manganese mutagenesis in vitro
-
Beckman, R. A., Mildvan, A. S., and Loeb, L. A. (1985). On the fidelity of DNA replication: Manganese mutagenesis in vitro. Biochemistry 24, 5810-5817.
-
(1985)
Biochemistry
, vol.24
, pp. 5810-5817
-
-
Beckman, R.A.1
Mildvan, A.S.2
Loeb, L.A.3
-
11
-
-
23744436747
-
Crystal structures of the RNA-dependent RNA polymerase genotype 2a of hepatitis C virus reveal two conformations and suggest mechanisms of inhibition by non-nucleoside inhibitors
-
Biswal, B. K., Cherney, M.M., Wang, M., Chan, L., Yannopoulos, C. G., Bilimoria, D., Nicolas, O., Bedard, J., and James, M. N. (2005). Crystal structures of the RNA-dependent RNA polymerase genotype 2a of hepatitis C virus reveal two conformations and suggest mechanisms of inhibition by non-nucleoside inhibitors. J Biol Chem 280, 18202-18210.
-
(2005)
J Biol Chem
, vol.280
, pp. 18202-18210
-
-
Biswal, B.K.1
Cherney, M.M.2
Wang, M.3
Chan, L.4
Yannopoulos, C.G.5
Bilimoria, D.6
Nicolas, O.7
Bedard, J.8
James, M.N.9
-
12
-
-
0032005866
-
Structural and functional insights provided by crystal structures of DNA polymerases and their substrate complexes
-
Brautigam, C. A., and Steitz, T. A. (1998). Structural and functional insights provided by crystal structures of DNA polymerases and their substrate complexes. Curr Opin Struct Biol 8, 54-63.
-
(1998)
Curr Opin Struct Biol
, vol.8
, pp. 54-63
-
-
Brautigam, C.A.1
Steitz, T.A.2
-
13
-
-
0036120573
-
Structural analysis of the hepatitis C virus RNA polymerase in complex with ribonucleotides
-
Bressanelli, S., Tomei, L., Rey, F. A., and De Francesco, R. (2002). Structural analysis of the hepatitis C virus RNA polymerase in complex with ribonucleotides. J Virol 76, 3482-3492.
-
(2002)
J Virol
, vol.76
, pp. 3482-3492
-
-
Bressanelli, S.1
Tomei, L.2
Rey, F.A.3
De Francesco, R.4
-
14
-
-
0033539482
-
Crystal structure of the RNA-dependent RNA polymerase of hepatitis C virus
-
Bressanelli, S., Tomei, L., Roussel, A., Incitti, I., Vitale, R. L., Mathieu, M., De Francesco, R., and Rey, F. A. (1999). Crystal structure of the RNA-dependent RNA polymerase of hepatitis C virus. Proc Natl Acad Sci USA 96, 13034-13039.
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 13034-13039
-
-
Bressanelli, S.1
Tomei, L.2
Roussel, A.3
Incitti, I.4
Vitale, R.L.5
Mathieu, M.6
De Francesco, R.7
Rey, F.A.8
-
15
-
-
0037386414
-
A structural and primary sequence comparison of the viral RNA-dependent RNA polymerases
-
Bruenn, J. A. (2003). A structural and primary sequence comparison of the viral RNA-dependent RNA polymerases. Nucleic Acids Res 31, 1821-1829.
-
(2003)
Nucleic Acids Res
, vol.31
, pp. 1821-1829
-
-
Bruenn, J.A.1
-
16
-
-
0035826258
-
A mechanism for initiating RNA-dependent RNA polymerization
-
Butcher, S. J., Grimes, J. M., Makeyev, E. V., Bamford, D. H., and Stuart, D. I. (2001). A mechanism for initiating RNA-dependent RNA polymerization. Nature 410, 235-240.
-
(2001)
Nature
, vol.410
, pp. 235-240
-
-
Butcher, S.J.1
Grimes, J.M.2
Makeyev, E.V.3
Bamford, D.H.4
Stuart, D.I.5
-
17
-
-
11844283982
-
Incorporation fidelity of the viral RNAdependent RNA polymerase: A kinetic, thermodynamic and structural perspective
-
Castro, C., Arnold, J. J., and Cameron, C. E. (2005). Incorporation fidelity of the viral RNAdependent RNA polymerase: A kinetic, thermodynamic and structural perspective. Virus Res 107, 141-149.
-
(2005)
Virus Res
, vol.107
, pp. 141-149
-
-
Castro, C.1
Arnold, J.J.2
Cameron, C.E.3
-
18
-
-
0033752274
-
De novo synthesis of minus strand RNA by the rotavirus RNA polymerase in a cell-free system involves a novel mechanism of initiation
-
Chen, D., and Patton, J. T. (2000). De novo synthesis of minus strand RNA by the rotavirus RNA polymerase in a cell-free system involves a novel mechanism of initiation. Rna 6, 1455-1467.
-
(2000)
Rna
, vol.6
, pp. 1455-1467
-
-
Chen, D.1
Patton, J.T.2
-
19
-
-
33745832659
-
The structure of bovine viral diarrhea virus RNA-dependent RNA polymerase and its amino-terminal domain
-
Choi, K. H., Gallei, A., Becher, P., and Rossmann, M. G. (2006). The structure of bovine viral diarrhea virus RNA-dependent RNA polymerase and its amino-terminal domain. Structure 14, 1107-1113.
-
(2006)
Structure
, vol.14
, pp. 1107-1113
-
-
Choi, K.H.1
Gallei, A.2
Becher, P.3
Rossmann, M.G.4
-
20
-
-
1842481188
-
The structure of the RNA-dependent RNA polymerase from bovine viral diarrhea virus establishes the role of GTP in de novo initiation
-
Choi, K. H., Groarke, J. M., Young, D. C., Kuhn, R. J., Smith, J. L., Pevear, D. C., and Rossmann, M. G. (2004). The structure of the RNA-dependent RNA polymerase from bovine viral diarrhea virus establishes the role of GTP in de novo initiation. Proc Natl Acad Sci USA 101, 4425-4430.
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 4425-4430
-
-
Choi, K.H.1
Groarke, J.M.2
Young, D.C.3
Kuhn, R.J.4
Smith, J.L.5
Pevear, D.C.6
Rossmann, M.G.7
-
21
-
-
23944482649
-
Challenges and successes in developing new therapies for hepatitis C
-
De Francesco, R., and Migliaccio, G. (2005). Challenges and successes in developing new therapies for hepatitis C. Nature 436, 953-960.
-
(2005)
Nature
, vol.436
, pp. 953-960
-
-
De Francesco, R.1
Migliaccio, G.2
-
22
-
-
23744452229
-
Interdomain communication in hepatitis C virus polymerase abolished by small molecule inhibitors bound to a novel allosteric site
-
Di Marco, S., Volpari, C., Tomei, L., Altamura, S., Harper, S., Narjes, F., Koch, U., Rowley, M., De Francesco, R., Migliaccio, G., and Carfi, A. (2005). Interdomain communication in hepatitis C virus polymerase abolished by small molecule inhibitors bound to a novel allosteric site. J Biol Chem 280, 29765-29770.
-
(2005)
J Biol Chem
, vol.280
, pp. 29765-29770
-
-
Di Marco, S.1
Volpari, C.2
Tomei, L.3
Altamura, S.4
Harper, S.5
Narjes, F.6
Koch, U.7
Rowley, M.8
De Francesco, R.9
Migliaccio, G.10
Carfi, A.11
-
23
-
-
34547178347
-
Sequential structures provide insights into the fidelity of RNA replication
-
Ferrer-Orta, C., Arias, A., Pérez-Luque, R., Escarmís, C., Domingo, E., and Verdaguer, N. (2007). Sequential structures provide insights into the fidelity of RNA replication. Proc Natl Acad Sci U S A. 104, 9463-9468.
-
(2007)
Proc Natl Acad Sci U S a
, vol.104
, pp. 9463-9468
-
-
Ferrer-Orta, C.1
Arias, A.2
Pérez-Luque, R.3
Escarmís, C.4
Domingo, E.5
Verdaguer, N.6
-
24
-
-
33644519317
-
The structure of a protein primer-polymerase complex in the initiation of genome replication
-
Ferrer-Orta, C., Arias, A., Agudo, R., Perez-Luque, R., Escarmis, C., Domingo, E., and Verdaguer, N. (2006a). The structure of a protein primer-polymerase complex in the initiation of genome replication. Embo J 25, 880-888.
-
(2006)
Embo J
, vol.25
, pp. 880-888
-
-
Ferrer-Orta, C.1
Arias, A.2
Agudo, R.3
Perez-Luque, R.4
Escarmis, C.5
Domingo, E.6
Verdaguer, N.7
-
25
-
-
32344432085
-
A comparison of viral RNAdependent RNA polymerases
-
Ferrer-Orta, C., Arias, A., Escarmis, C., and Verdaguer, N. (2006b). A comparison of viral RNAdependent RNA polymerases. Curr Opin Struct Biol 16, 27-34.
-
(2006)
Curr Opin Struct Biol
, vol.16
, pp. 27-34
-
-
Ferrer-Orta, C.1
Arias, A.2
Escarmis, C.3
Verdaguer, N.4
-
26
-
-
8744222695
-
Structure of foot-and-mouth disease virus RNA-dependent RNA polymerase and its complex with a template-primer RNA
-
Ferrer-Orta, C., Arias, A., Perez-Luque, R., Escarmis, C., Domingo, E., and Verdaguer, N. (2004). Structure of foot-and-mouth disease virus RNA-dependent RNA polymerase and its complex with a template-primer RNA. J Biol Chem 279, 47212-47221.
-
(2004)
J Biol Chem
, vol.279
, pp. 47212-47221
-
-
Ferrer-Orta, C.1
Arias, A.2
Perez-Luque, R.3
Escarmis, C.4
Domingo, E.5
Verdaguer, N.6
-
27
-
-
33846850610
-
Structural and functional characterization of sapovirus RNA-dependent RNA polymerase
-
Fullerton, S. W., Blaschke, M., Coutard, B., Gebhardt, J., Gorbalenya, A., Canard, B., Tucker, P. A., and Rohayem, J. (2007). Structural and functional characterization of sapovirus RNA-dependent RNA polymerase. J Virol 81, 1858-1871.
-
(2007)
J Virol
, vol.81
, pp. 1858-1871
-
-
Fullerton, S.W.1
Blaschke, M.2
Coutard, B.3
Gebhardt, J.4
Gorbalenya, A.5
Canard, B.6
Tucker, P.A.7
Rohayem, J.8
-
28
-
-
2442461170
-
Poliovirus RNA-dependent RNA polymerase (3Dpol): Kinetic, thermodynamic, and structural analysis of ribonucleotide selection
-
Gohara, D. W., Arnold, J. J., and Cameron, C. E. (2004). Poliovirus RNA-dependent RNA polymerase (3Dpol): kinetic, thermodynamic, and structural analysis of ribonucleotide selection. Biochemistry 43, 5149-5158.
-
(2004)
Biochemistry
, vol.43
, pp. 5149-5158
-
-
Gohara, D.W.1
Arnold, J.J.2
Cameron, C.E.3
-
29
-
-
0034682792
-
Poliovirus RNA-dependent RNA polymerase (3Dpol): Structural, biochemical, and biological analysis of conserved structural motifs A and B
-
Gohara, D. W., Crotty, S., Arnold, J. J., Yoder, J. D., Andino, R., and Cameron, C. E. (2000). Poliovirus RNA-dependent RNA polymerase (3Dpol): Structural, biochemical, and biological analysis of conserved structural motifs A and B. J Biol Chem 275, 25523-25532.
-
(2000)
J Biol Chem
, vol.275
, pp. 25523-25532
-
-
Gohara, D.W.1
Crotty, S.2
Arnold, J.J.3
Yoder, J.D.4
Andino, R.5
Cameron, C.E.6
-
30
-
-
0020619684
-
On the enzymatic basis for mutagenesis by manganese
-
Goodman, M. F., Keener, S., Guidotti, S., and Branscomb, E. W. (1983). On the enzymatic basis for mutagenesis by manganese. J Biol Chem 258, 3469-3475.
-
(1983)
J Biol Chem
, vol.258
, pp. 3469-3475
-
-
Goodman, M.F.1
Keener, S.2
Guidotti, S.3
Branscomb, E.W.4
-
31
-
-
0036434498
-
The palm subdomain-based active site is internally permuted in viral RNA-dependent RNA polymerases of an ancient lineage
-
Gorbalenya, A. E., Pringle, F. M., Zeddam, J. L., Luke, B. T., Cameron, C. E., Kalmakoff, J., Hanzlik, T. N., Gordon, K. H., and Ward, V. K. (2002). The palm subdomain-based active site is internally permuted in viral RNA-dependent RNA polymerases of an ancient lineage. J Mol Biol 324, 47-62.
-
(2002)
J Mol Biol
, vol.324
, pp. 47-62
-
-
Gorbalenya, A.E.1
Pringle, F.M.2
Zeddam, J.L.3
Luke, B.T.4
Cameron, C.E.5
Kalmakoff, J.6
Hanzlik, T.N.7
Gordon, K.H.8
Ward, V.K.9
-
32
-
-
0031571638
-
Structure of the RNA-dependent RNA polymerase of poliovirus
-
Hansen, J. L., Long, A. M., and Schultz, S. C. (1997). Structure of the RNA-dependent RNA polymerase of poliovirus. Structure 5, 1109-1122.
-
(1997)
Structure
, vol.5
, pp. 1109-1122
-
-
Hansen, J.L.1
Long, A.M.2
Schultz, S.C.3
-
33
-
-
0032509209
-
Functional analysis of amino acid residues constituting the dNTP binding pocket of HIV-1 reverse transcriptase
-
Harris, D., Kaushik, N., Pandey, P. K., Yadav, P. N., and Pandey, V. N. (1998). Functional analysis of amino acid residues constituting the dNTP binding pocket of HIV-1 reverse transcriptase. J Biol Chem 273, 33624-33634.
-
(1998)
J Biol Chem
, vol.273
, pp. 33624-33634
-
-
Harris, D.1
Kaushik, N.2
Pandey, P.K.3
Yadav, P.N.4
Pandey, V.N.5
-
34
-
-
0035283140
-
Oligomeric structures of poliovirus polymerase are important for function
-
Hobson, S. D., Rosenblum, E. S., Richards, O. C., Richmond, K., Kirkegaard, K., and Schultz, S. C. (2001). Oligomeric structures of poliovirus polymerase are important for function. Embo J 20, 1153-1163.
-
(2001)
Embo J
, vol.20
, pp. 1153-1163
-
-
Hobson, S.D.1
Rosenblum, E.S.2
Richards, O.C.3
Richmond, K.4
Kirkegaard, K.5
Schultz, S.C.6
-
35
-
-
0022979270
-
RNA polymerase of influenza virus. Dinucleotide-primed initiation of transcription at specific positions on viral RNA
-
Honda, A., Mizumoto, K., and Ishihama, A. (1986). RNA polymerase of influenza virus. Dinucleotide-primed initiation of transcription at specific positions on viral RNA. J Biol Chem 261, 5987-5991.
-
(1986)
J Biol Chem
, vol.261
, pp. 5987-5991
-
-
Honda, A.1
Mizumoto, K.2
Ishihama, A.3
-
36
-
-
0032573488
-
Structure of a covalently trapped catalytic complex of HIV-1 reverse transcriptase: Implications for drug resistance
-
Huang, H., Chopra, R., Verdine, G. L., and Harrison, S. C. (1998). Structure of a covalently trapped catalytic complex of HIV-1 reverse transcriptase: Implications for drug resistance. Science 282, 1669-1675.
-
(1998)
Science
, vol.282
, pp. 1669-1675
-
-
Huang, H.1
Chopra, R.2
Verdine, G.L.3
Harrison, S.C.4
-
37
-
-
0030727136
-
Determinants of ribose specificity in RNA polymerization: Effects of Mn2+ and deoxynucleoside monophosphate incorporation into transcripts
-
Huang, Y., Beaudry, A., McSwiggen, J., and Sousa, R. (1997). Determinants of ribose specificity in RNA polymerization: effects of Mn2+ and deoxynucleoside monophosphate incorporation into transcripts. Biochemistry 36, 13718-13728.
-
(1997)
Biochemistry
, vol.36
, pp. 13718-13728
-
-
Huang, Y.1
Beaudry, A.2
McSwiggen, J.3
Sousa, R.4
-
38
-
-
0035450225
-
De novo initiation of viral RNA-dependent RNA synthesis
-
Kao, C. C., Singh, P., and Ecker, D. J. (2001). De novo initiation of viral RNA-dependent RNA synthesis. Virology 287, 251-260.
-
(2001)
Virology
, vol.287
, pp. 251-260
-
-
Kao, C.C.1
Singh, P.2
Ecker, D.J.3
-
39
-
-
0034468107
-
Template requirements for RNA synthesis by a recombinant hepatitis C virus RNA-dependent RNA polymerase
-
Kao, C. C., Yang, X., Kline, A., Wang, Q. M., Barket, D., and Heinz, B. A. (2000). Template requirements for RNA synthesis by a recombinant hepatitis C virus RNA-dependent RNA polymerase. J Virol 74, 11121-11128.
-
(2000)
J Virol
, vol.74
, pp. 11121-11128
-
-
Kao, C.C.1
Yang, X.2
Kline, A.3
Wang, Q.M.4
Barket, D.5
Heinz, B.A.6
-
40
-
-
33644864228
-
Functional evidence for a small and rigid active site in a high fidelity DNA polymerase: Probing T7 DNA polymerase with variably sized base pairs
-
Kim, T. W., Brieba, L. G., Ellenberger, T., and Kool, E. T. (2006). Functional evidence for a small and rigid active site in a high fidelity DNA polymerase: Probing T7 DNA polymerase with variably sized base pairs. J Biol Chem 281, 2289-2295.
-
(2006)
J Biol Chem
, vol.281
, pp. 2289-2295
-
-
Kim, T.W.1
Brieba, L.G.2
Ellenberger, T.3
Kool, E.T.4
-
41
-
-
0035997351
-
Active site tightness and substrate fit in DNA replication
-
Kool, E. T. (2002). Active site tightness and substrate fit in DNA replication. Annu Rev Biochem 71, 191-219.
-
(2002)
Annu Rev Biochem
, vol.71
, pp. 191-219
-
-
Kool, E.T.1
-
42
-
-
0025743809
-
The phylogeny of RNA-dependent RNA polymerases of positive-strand RNA viruses
-
Koonin, E. V. (1991). The phylogeny of RNA-dependent RNA polymerases of positive-strand RNA viruses. J Gen Virol 72 (Pt 9), 2197-2206.
-
(1991)
J Gen Virol
, vol.72
, pp. 2197-2206
-
-
Koonin, E.V.1
-
43
-
-
0037064077
-
Modulation of hepatitis C virus RNA-dependent RNA polymerase activity by structure-based site-directed mutagenesis
-
Labonte, P., Axelrod, V., Agarwal, A., Aulabaugh, A., Amin, A., and Mak, P. (2002). Modulation of hepatitis C virus RNA-dependent RNA polymerase activity by structure-based site-directed mutagenesis. J Biol Chem 277, 38838-38846.
-
(2002)
J Biol Chem
, vol.277
, pp. 38838-38846
-
-
Labonte, P.1
Axelrod, V.2
Agarwal, A.3
Aulabaugh, A.4
Amin, A.5
Mak, P.6
-
44
-
-
0032876683
-
Crystal structure of the RNA-dependent RNA polymerase from hepatitis C virus reveals a fully encircled active site
-
Lesburg, C. A., Cable, M. B., Ferrari, E., Hong, Z., Mannarino, A. F., and Weber, P. C. (1999). Crystal structure of the RNA-dependent RNA polymerase from hepatitis C virus reveals a fully encircled active site. Nat Struct Biol 6, 937-943.
-
(1999)
Nat Struct Biol
, vol.6
, pp. 937-943
-
-
Lesburg, C.A.1
Cable, M.B.2
Ferrari, E.3
Hong, Z.4
Mannarino, A.F.5
Weber, P.C.6
-
45
-
-
0041707714
-
Identification of a C-terminal regulatory motif in hepatitis C virus RNA-dependent RNA polymerase: Structural and biochemical analysis
-
Leveque, V. J., Johnson, R. B., Parsons, S., Ren, J., Xie, C., Zhang, F., and Wang, Q. M. (2003). Identification of a C-terminal regulatory motif in hepatitis C virus RNA-dependent RNA polymerase: Structural and biochemical analysis. J Virol 77, 9020-9028.
-
(2003)
J Virol
, vol.77
, pp. 9020-9028
-
-
Leveque, V.J.1
Johnson, R.B.2
Parsons, S.3
Ren, J.4
Xie, C.5
Zhang, F.6
Wang, Q.M.7
-
46
-
-
4143147318
-
The crystal structure of the RNA-dependent RNA polymerase from human rhinovirus: A dual function target for common cold antiviral therapy
-
Love, R. A., Maegley, K. A., Yu, X., Ferre, R. A., Lingardo, L. K., Diehl, W., Parge, H. E., Dragovich, P. S., and Fuhrman, S. A. (2004). The crystal structure of the RNA-dependent RNA polymerase from human rhinovirus: A dual function target for common cold antiviral therapy. Structure 12, 1533-1544.
-
(2004)
Structure
, vol.12
, pp. 1533-1544
-
-
Love, R.A.1
Maegley, K.A.2
Yu, X.3
Ferre, R.A.4
Lingardo, L.K.5
Diehl, W.6
Parge, H.E.7
Dragovich, P.S.8
Fuhrman, S.A.9
-
47
-
-
0037013317
-
Similar structural basis for membrane localization and protein priming by an RNA-dependent RNA polymerase
-
Lyle, J. M., Clewell, A., Richmond, K., Richards, O. C., Hope, D. A., Schultz, S. C., and Kirkegaard, K. (2002). Similar structural basis for membrane localization and protein priming by an RNA-dependent RNA polymerase. J Biol Chem 277, 16324-16331.
-
(2002)
J Biol Chem
, vol.277
, pp. 16324-16331
-
-
Lyle, J.M.1
Clewell, A.2
Richmond, K.3
Richards, O.C.4
Hope, D.A.5
Schultz, S.C.6
Kirkegaard, K.7
-
48
-
-
0034669114
-
The polymerase subunit of a dsRNA virus plays a central role in the regulation of viral RNA metabolism
-
Makeyev, E. V., and Bamford, D. H. (2000a). The polymerase subunit of a dsRNA virus plays a central role in the regulation of viral RNA metabolism. Embo J 19, 6275-6284.
-
(2000)
Embo J
, vol.19
, pp. 6275-6284
-
-
Makeyev, E.V.1
Bamford, D.H.2
-
49
-
-
0034602836
-
Replicase activity of purified recombinant protein P2 of double-stranded RNA bacteriophage phi6
-
Makeyev, E. V., and Bamford, D. H. (2000b). Replicase activity of purified recombinant protein P2 of double-stranded RNA bacteriophage phi6. Embo J 19, 124-133.
-
(2000)
Embo J
, vol.19
, pp. 124-133
-
-
Makeyev, E.V.1
Bamford, D.H.2
-
50
-
-
33947386595
-
Crystal structure of poliovirus 3CD protein: Virally encoded protease and precursor to the RNA-dependent RNA polymerase
-
Marcotte, L. L., Wass, A. B., Gohara, D. W., Pathak, H. B., Arnold, J. J., Filman, D. J., Cameron, C. E., and Hogle, J. M. (2007). Crystal structure of poliovirus 3CD protein: virally encoded protease and precursor to the RNA-dependent RNA polymerase. J Virol 81, 3583-3596.
-
(2007)
J Virol
, vol.81
, pp. 3583-3596
-
-
Marcotte, L.L.1
Wass, A.B.2
Gohara, D.W.3
Pathak, H.B.4
Arnold, J.J.5
Filman, D.J.6
Cameron, C.E.7
Hogle, J.M.8
-
51
-
-
19944407924
-
Factors required for the Uridylylation of the foot-and-mouth disease virus 3B1, 3B2, and 3B3 peptides by the RNA-dependent RNA polymerase (3Dpol) in vitro
-
Nayak, A., Goodfellow, I. G., and Belsham, G. J. (2005). Factors required for the Uridylylation of the foot-and-mouth disease virus 3B1, 3B2, and 3B3 peptides by the RNA-dependent RNA polymerase (3Dpol) in vitro. J Virol 79, 7698-7706.
-
(2005)
J Virol
, vol.79
, pp. 7698-7706
-
-
Nayak, A.1
Goodfellow, I.G.2
Belsham, G.J.3
-
52
-
-
0037059758
-
Crystal structures of active and inactive conformations of a caliciviral RNA-dependent RNA polymerase
-
Ng, K. K., Cherney, M. M., Vazquez, A. L., Machin, A., Alonso, J. M., Parra, F., and James, M. N. (2002). Crystal structures of active and inactive conformations of a caliciviral RNA-dependent RNA polymerase. J Biol Chem 277, 1381-1387.
-
(2002)
J Biol Chem
, vol.277
, pp. 1381-1387
-
-
Ng, K.K.1
Cherney, M.M.2
Vazquez, A.L.3
Machin, A.4
Alonso, J.M.5
Parra, F.6
James, M.N.7
-
53
-
-
1942501581
-
Crystal structure of norwalk virus polymerase reveals the carboxyl terminus in the active site cleft
-
Ng, K. K., Pendas-Franco, N., Rojo, J., Boga, J. A., Machin, A., Alonso, J. M., and Parra, F. (2004). Crystal structure of norwalk virus polymerase reveals the carboxyl terminus in the active site cleft. J Biol Chem 279, 16638-16645.
-
(2004)
J Biol Chem
, vol.279
, pp. 16638-16645
-
-
Ng, K.K.1
Pendas-Franco, N.2
Rojo, J.3
Boga, J.A.4
Machin, A.5
Alonso, J.M.6
Parra, F.7
-
54
-
-
0032567393
-
Analysis of RNA-dependent RNA polymerase structure and function as guided by known polymerase structures and computer predictions of secondary structure
-
O'Reilly, E. K., and Kao, C. C. (1998). Analysis of RNA-dependent RNA polymerase structure and function as guided by known polymerase structures and computer predictions of secondary structure. Virology 252, 287-303.
-
(1998)
Virology
, vol.252
, pp. 287-303
-
-
O'Reilly, E.K.1
Kao, C.C.2
-
55
-
-
0037200001
-
Structure-function relationships of the RNA-dependent RNA polymerase from poliovirus (3Dpol). A surface of the primary oligomerization domain functions in capsid precursor processing and VPg uridylylation
-
Pathak, H. B., Ghosh, S. K., Roberts, A. W., Sharma, S. D., Yoder, J. D., Arnold, J. J., Gohara, D. W., Barton, D. J., Paul, A. V., and Cameron, C. E. (2002). Structure-function relationships of the RNA-dependent RNA polymerase from poliovirus (3Dpol). A surface of the primary oligomerization domain functions in capsid precursor processing and VPg uridylylation. J Biol Chem 277, 31551-31562.
-
(2002)
J Biol Chem
, vol.277
, pp. 31551-31562
-
-
Pathak, H.B.1
Ghosh, S.K.2
Roberts, A.W.3
Sharma, S.D.4
Yoder, J.D.5
Arnold, J.J.6
Gohara, D.W.7
Barton, D.J.8
Paul, A.V.9
Cameron, C.E.10
-
56
-
-
0033766003
-
Identification of an RNA hairpin in poliovirus RNA that serves as the primary template in the in vitro uridylylation of VPg
-
Paul, A. V., Rieder, E., Kim, D. W., van Boom, J. H., and Wimmer, E. (2000). Identification of an RNA hairpin in poliovirus RNA that serves as the primary template in the in vitro uridylylation of VPg. J Virol 74, 10359-10370.
-
(2000)
J Virol
, vol.74
, pp. 10359-10370
-
-
Paul, A.V.1
Rieder, E.2
Kim, D.W.3
Van Boom, J.H.4
Wimmer, E.5
-
57
-
-
0032554886
-
Protein-primed RNA synthesis by purified poliovirus RNA polymerase
-
Paul, A. V., van Boom, J. H., Filippov, D., and Wimmer, E. (1998). Protein-primed RNA synthesis by purified poliovirus RNA polymerase. Nature 393, 280-284.
-
(1998)
Nature
, vol.393
, pp. 280-284
-
-
Paul, A.V.1
Van Boom, J.H.2
Filippov, D.3
Wimmer, E.4
-
58
-
-
0023892253
-
Enzymatic activity of poliovirus RNA polymerase synthesized in Escherichia coli from viral cDNA
-
Rothstein, M. A., Richards, O. C., Amin, C., and Ehrenfeld, E. (1988). Enzymatic activity of poliovirus RNA polymerase synthesized in Escherichia coli from viral cDNA. Virology 164, 301-308.
-
(1988)
Virology
, vol.164
, pp. 301-308
-
-
Rothstein, M.A.1
Richards, O.C.2
Amin, C.3
Ehrenfeld, E.4
-
59
-
-
1242283840
-
The structural basis for RNA specificity and Ca2+ inhibition of an RNA-dependent RNA polymerase
-
Salgado, P. S., Makeyev, E. V., Butcher, S. J., Bamford, D. H., Stuart, D. I., and Grimes, J. M. (2004). The structural basis for RNA specificity and Ca2+ inhibition of an RNA-dependent RNA polymerase. Structure 12, 307-316.
-
(2004)
Structure
, vol.12
, pp. 307-316
-
-
Salgado, P.S.1
Makeyev, E.V.2
Butcher, S.J.3
Bamford, D.H.4
Stuart, D.I.5
Grimes, J.M.6
-
60
-
-
0021288120
-
Effects of Ca2+ and Mg2+ on the switch-on of transcriptase function in reovirus in vitro
-
Sargent, M. D., and Borsa, J. (1984). Effects of Ca2+ and Mg2+ on the switch-on of transcriptase function in reovirus in vitro. Can J Biochem Cell Biol 62, 162-169.
-
(1984)
Can J Biochem Cell Biol
, vol.62
, pp. 162-169
-
-
Sargent, M.D.1
Borsa, J.2
-
61
-
-
33744984790
-
NMR structure of the viral peptide linked to the genome (VPg) of poliovirus
-
Schein, C. H., Oezguen, N., Volk, D. E., Garimella, R., Paul, A., and Braun, W. (2006). NMR structure of the viral peptide linked to the genome (VPg) of poliovirus. Peptides 27, 1676-1684.
-
(2006)
Peptides
, vol.27
, pp. 1676-1684
-
-
Schein, C.H.1
Oezguen, N.2
Volk, D.E.3
Garimella, R.4
Paul, A.5
Braun, W.6
-
62
-
-
0032518374
-
A mechanism for all polymerases
-
Steitz, T. A. (1998). A mechanism for all polymerases. Nature 391, 231-232.
-
(1998)
Nature
, vol.391
, pp. 231-232
-
-
Steitz, T.A.1
-
63
-
-
0028088152
-
The alphaviruses: Gene expression, replication, and evolution
-
Strauss, J. H., and Strauss, E. G. (1994). The alphaviruses: gene expression, replication, and evolution. Microbiol Rev 58, 491-562.
-
(1994)
Microbiol Rev
, vol.58
, pp. 491-562
-
-
Strauss, J.H.1
Strauss, E.G.2
-
64
-
-
0006962619
-
Effect of manganese ions on the incorporation of dideoxynucleotides by bacteriophage T7 DNA polymerase and Escherichia coli DNA polymerase I
-
Tabor, S., and Richardson, C. C. (1989). Effect of manganese ions on the incorporation of dideoxynucleotides by bacteriophage T7 DNA polymerase and Escherichia coli DNA polymerase I. Proc Natl Acad Sci USA 86, 4076-4080.
-
(1989)
Proc Natl Acad Sci USA
, vol.86
, pp. 4076-4080
-
-
Tabor, S.1
Richardson, C.C.2
-
65
-
-
18744392514
-
RNA synthesis in a cage - structural studies of reovirus polymerase lambda3
-
Tao, Y., Farsetta, D. L., Nibert, M. L., and Harrison, S. C. (2002). RNA synthesis in a cage - structural studies of reovirus polymerase lambda3. Cell 111, 733-745.
-
(2002)
Cell
, vol.111
, pp. 733-745
-
-
Tao, Y.1
Farsetta, D.L.2
Nibert, M.L.3
Harrison, S.C.4
-
66
-
-
33344464455
-
Nucleotide channel of RNA-dependent RNA polymerase used for intermolecular uridylylation of protein primer
-
Tellez, A. B., Crowder, S., Spagnolo, J. F., Thompson, A. A., Peersen, O. B., Brutlag, D. L., and Kirkegaard, K. (2006). Nucleotide channel of RNA-dependent RNA polymerase used for intermolecular uridylylation of protein primer. J Mol Biol 357, 665-675.
-
(2006)
J Mol Biol
, vol.357
, pp. 665-675
-
-
Tellez, A.B.1
Crowder, S.2
Spagnolo, J.F.3
Thompson, A.A.4
Peersen, O.B.5
Brutlag, D.L.6
Kirkegaard, K.7
-
67
-
-
0018800386
-
Initiation of RNA synthesis in vitro by vesicular stomatitis virus
-
Testa, D., and Banerjee, A. K. (1979). Initiation of RNA synthesis in vitro by vesicular stomatitis virus. Role of ATP. J Biol Chem 254, 2053-2058.
-
(1979)
Role of ATP. J Biol Chem
, vol.254
, pp. 2053-2058
-
-
Testa, D.1
Banerjee, A.K.2
-
68
-
-
33846833843
-
Stabilization of poliovirus polymerase by NTP binding and fingers-thumb interactions
-
Thompson, A. A., Albertini, R. A., and Peersen, O. B. (2007). Stabilization of poliovirus polymerase by NTP binding and fingers-thumb interactions. J Mol Biol 366, 1459-1474.
-
(2007)
J Mol Biol
, vol.366
, pp. 1459-1474
-
-
Thompson, A.A.1
Albertini, R.A.2
Peersen, O.B.3
-
69
-
-
4644238112
-
Structural basis for proteolysis-dependent activation of the poliovirus RNA-dependent RNA polymerase
-
Thompson, A. A., and Peersen, O. B. (2004). Structural basis for proteolysis-dependent activation of the poliovirus RNA-dependent RNA polymerase. Embo J 23, 3462-3471.
-
(2004)
Embo J
, vol.23
, pp. 3462-3471
-
-
Thompson, A.A.1
Peersen, O.B.2
-
70
-
-
0029130267
-
Differentiation between minus- And plus-strand synthesis: Polymerase activity of dsRNA bacteriophage phi 6 in an in vitro packaging and replication system
-
van Dijk, A. A., Frilander, M., and Bamford, D. H. (1995). Differentiation between minus- And plus-strand synthesis: Polymerase activity of dsRNA bacteriophage phi 6 in an in vitro packaging and replication system. Virology 211, 320-323.
-
(1995)
Virology
, vol.211
, pp. 320-323
-
-
Van Dijk, A.A.1
Frilander, M.2
Bamford, D.H.3
-
71
-
-
2442677715
-
Initiation of viral RNA-dependent RNA polymerization
-
van Dijk, A. A., Makeyev, E. V., and Bamford, D. H. (2004). Initiation of viral RNA-dependent RNA polymerization. J Gen Virol 85, 1077-1093.
-
(2004)
J Gen Virol
, vol.85
, pp. 1077-1093
-
-
Van Dijk, A.A.1
Makeyev, E.V.2
Bamford, D.H.3
-
72
-
-
0037225770
-
Two distinct mechanisms ensure transcriptional polarity in double-stranded RNA bacteriophages
-
Yang, H., Makeyev, E. V., Butcher, S. J., Gaidelyte, A., and Bamford, D. H. (2003). Two distinct mechanisms ensure transcriptional polarity in double-stranded RNA bacteriophages. J Virol 77, 1195-1203.
-
(2003)
J Virol
, vol.77
, pp. 1195-1203
-
-
Yang, H.1
Makeyev, E.V.2
Butcher, S.J.3
Gaidelyte, A.4
Bamford, D.H.5
-
73
-
-
34247610261
-
The crystal Structure of the Dengue virus RNA-dependent RNA polymerase catalytic domain at 1.85 °Aresolution
-
Yap, T. L., Xu, T., Chen, Y. L., Malet, H., Egloff, M. P., Canard, B., Vasudevan, S. G., and Lescar, J. (2007). The crystal Structure of the Dengue virus RNA-dependent RNA polymerase catalytic domain at 1.85 °Aresolution. J Virol 81, 4753-4765.
-
(2007)
J Virol
, vol.81
, pp. 4753-4765
-
-
Yap, T.L.1
Xu, T.2
Chen, Y.L.3
Malet, H.4
Egloff, M.P.5
Canard, B.6
Vasudevan, S.G.7
Lescar, J.8
-
74
-
-
0033803374
-
Template/primer requirements and single nucleotide incorporation by hepatitis C virus nonstructural protein 5B polymerase
-
Zhong, W., Ferrari, E., Lesburg, C. A., Maag, D., Ghosh, S. K., Cameron, C. E., Lau, J. Y., and Hong, Z. (2000). Template/primer requirements and single nucleotide incorporation by hepatitis C virus nonstructural protein 5B polymerase. J Virol 74, 9134-9143.
-
(2000)
J Virol
, vol.74
, pp. 9134-9143
-
-
Zhong, W.1
Ferrari, E.2
Lesburg, C.A.3
Maag, D.4
Ghosh, S.K.5
Cameron, C.E.6
Lau, J.Y.7
Hong, Z.8
|