-
3
-
-
0034682792
-
pol): Structural, biochemical, and biological analysis of conserved structural motifs A and B
-
pol): Structural, biochemical, and biological analysis of conserved structural motifs A and B, J. Biol. Chem. 275, 25523-25532.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 25523-25532
-
-
Gohara, D.W.1
Crotty, S.2
Arnold, J.J.3
Yoder, J.D.4
Andino, R.5
Cameron, C.E.6
-
4
-
-
0031571638
-
Structure of the RNA-dependent RNA polymerase of poliovirus
-
Hansen, J. L., Long, A. M., and Schultz, S. C. (1997) Structure of the RNA-dependent RNA polymerase of poliovirus, Structure 5, 1109-1122.
-
(1997)
Structure
, vol.5
, pp. 1109-1122
-
-
Hansen, J.L.1
Long, A.M.2
Schultz, S.C.3
-
5
-
-
0032573488
-
Structure of a covalently trapped catalytic complex of HIV-1 reverse transcriptase: Implications for drug resistance
-
Huang, H., Chopra, R., Verdine, G. L., and Harrison, S. C. (1998) Structure of a covalently trapped catalytic complex of HIV-1 reverse transcriptase: implications for drug resistance, Science 282, 1669-1675.
-
(1998)
Science
, vol.282
, pp. 1669-1675
-
-
Huang, H.1
Chopra, R.2
Verdine, G.L.3
Harrison, S.C.4
-
6
-
-
0033212780
-
pol) by ubiquitin-protease-mediated cleavage in Escherichia coli
-
pol) by ubiquitin-protease-mediated cleavage in Escherichia coli, Protein Expression Purif. 17, 128-138.
-
(1999)
Protein Expression Purif.
, vol.17
, pp. 128-138
-
-
Gohara, D.W.1
Ha, C.S.2
Kumar, S.3
Ghosh, B.4
Arnold, J.J.5
Wisniewski, T.J.6
Cameron, C.E.7
-
7
-
-
0034090927
-
pol): Assembly of stable, elongation-competent complexes by using a symmetrical primer-template substrate (sym/sub)
-
pol): Assembly of stable, elongation-competent complexes by using a symmetrical primer-template substrate (sym/sub), J. Biol. Chem. 275, 5329-5336.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 5329-5336
-
-
Arnold, J.J.1
Cameron, C.E.2
-
8
-
-
0026026192
-
An induced-fit kinetic mechanism for DNA replication fidelity: Direct measurement by single-turnover kinetics
-
Wong, I., Patel, S. S., and Johnson, K. A. (1991) An induced-fit kinetic mechanism for DNA replication fidelity: direct measurement by single-turnover kinetics, Biochemistry 30, 526-537
-
(1991)
Biochemistry
, vol.30
, pp. 526-537
-
-
Wong, I.1
Patel, S.S.2
Johnson, K.A.3
-
9
-
-
0026033193
-
Pre-steady-state kinetic analysis of processive DNA replication including complete characterization of an exonuclease-deficient mutant
-
Patel, S. S., Wong, I., and Johnson, K. A. (1991) Pre-steady-state kinetic analysis of processive DNA replication including complete characterization of an exonuclease-deficient mutant, Biochemistry 30, 511-525.
-
(1991)
Biochemistry
, vol.30
, pp. 511-525
-
-
Patel, S.S.1
Wong, I.2
Johnson, K.A.3
-
10
-
-
0025093185
-
Estimating the contribution of engineered surface electrostatic interactions to protein stability by using double-mutant cycles
-
Serrano, L., Horovitz, A., Avron, B., Bycroft, M., and Fersht, A. R. (1990) Estimating the contribution of engineered surface electrostatic interactions to protein stability by using double-mutant cycles, Biochemistry 29, 9343-9352.
-
(1990)
Biochemistry
, vol.29
, pp. 9343-9352
-
-
Serrano, L.1
Horovitz, A.2
Avron, B.3
Bycroft, M.4
Fersht, A.R.5
-
11
-
-
0023657031
-
Dissection of the structure and activity of the tyrosyl-tRNA synthetase by site-directed mutagenesis
-
Fersht, A. R. (1987) Dissection of the structure and activity of the tyrosyl-tRNA synthetase by site-directed mutagenesis, Biochemistry 26, 8031-8307.
-
(1987)
Biochemistry
, vol.26
, pp. 8031-8307
-
-
Fersht, A.R.1
-
12
-
-
0026681635
-
Quantitative interpretations of double mutations of enzymes
-
Mildvan, A. S., Weber, D. J., and Kuliopulos, A. (1992) Quantitative interpretations of double mutations of enzymes, Arch. Biochem. Biophys. 294, 327-340.
-
(1992)
Arch. Biochem. Biophys.
, vol.294
, pp. 327-340
-
-
Mildvan, A.S.1
Weber, D.J.2
Kuliopulos, A.3
-
13
-
-
0033571463
-
Crystal structure of the RNA-dependent RNA polymerase of hepatitis C virus
-
Ago, H., Adachi, T., Yoshida, A., Yamamoto, M., Habuka, N., Yatsunami, K., and Miyano, M. (1999) Crystal structure of the RNA-dependent RNA polymerase of hepatitis C virus, Struct. Folding Des. 7, 1417-1426.
-
(1999)
Struct. Folding Des.
, vol.7
, pp. 1417-1426
-
-
Ago, H.1
Adachi, T.2
Yoshida, A.3
Yamamoto, M.4
Habuka, N.5
Yatsunami, K.6
Miyano, M.7
-
14
-
-
0032876683
-
Crystal structure of the RNA-dependent RNA polymerase from hepatitis C virus reveals a fully encircled active site
-
Lesburg, C. A., Cable, M. B., Ferrari, E., Hong, Z., Mannarino, A. F., and Weber, P. C. (1999) Crystal structure of the RNA-dependent RNA polymerase from hepatitis C virus reveals a fully encircled active site, Nat. Struct. Biol. 6, 937-943.
-
(1999)
Nat. Struct. Biol.
, vol.6
, pp. 937-943
-
-
Lesburg, C.A.1
Cable, M.B.2
Ferrari, E.3
Hong, Z.4
Mannarino, A.F.5
Weber, P.C.6
-
15
-
-
0033539482
-
Crystal structure of the RNA-dependent RNA polymerase of hepatitis C virus
-
Bressanelli, S., Tomei, L., Roussel, A., Incitti, I., Vitale, R. L., Mathieu, M., De Francesco, R., and Rey, F. A. (1999) Crystal structure of the RNA-dependent RNA polymerase of hepatitis C virus, Proc. Natl. Acad. Sci. U.S.A. 96, 13034-13039.
-
(1999)
Proc. Natl. Acad. Sci. U.S.A.
, vol.96
, pp. 13034-13039
-
-
Bressanelli, S.1
Tomei, L.2
Roussel, A.3
Incitti, I.4
Vitale, R.L.5
Mathieu, M.6
De Francesco, R.7
Rey, F.A.8
-
16
-
-
0037059758
-
Crystal structures of active and inactive conformations of a caliciviral RNA-dependent RNA polymerase
-
Ng, K. K., Cherney, M. M., Vazquez, A. L., Machin, A., Alonso, J. M., Parra, F., and James, M. N. (2002) Crystal structures of active and inactive conformations of a caliciviral RNA-dependent RNA polymerase, J. Biol. Chem. 277, 1381-1387.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 1381-1387
-
-
Ng, K.K.1
Cherney, M.M.2
Vazquez, A.L.3
Machin, A.4
Alonso, J.M.5
Parra, F.6
James, M.N.7
-
17
-
-
0035826258
-
A mechanism for initiating RNA-dependent RNA polymerization
-
Butcher, S. J., Grimes, J. M., Makeyev, E. V., Bamford, D. H., and Stuart, D. I. (2001) A mechanism for initiating RNA-dependent RNA polymerization, Nature 410, 235-240.
-
(2001)
Nature
, vol.410
, pp. 235-240
-
-
Butcher, S.J.1
Grimes, J.M.2
Makeyev, E.V.3
Bamford, D.H.4
Stuart, D.I.5
-
18
-
-
0025743809
-
The phylogeny of RNA-dependent RNA polymerases of positive-strand RNA viruses
-
Koonin, E. V. (1991) The phylogeny of RNA-dependent RNA polymerases of positive-strand RNA viruses, J. Gen. Virol. 72, 2197-2206.
-
(1991)
J. Gen. Virol.
, vol.72
, pp. 2197-2206
-
-
Koonin, E.V.1
-
19
-
-
0037388383
-
Processive DNA synthesis observed in a polymerase crystal suggests a mechanism for the prevention of frameshift mutations
-
Johnson, S. J., Taylor, J. S., and Beese L. S. (2003) Processive DNA synthesis observed in a polymerase crystal suggests a mechanism for the prevention of frameshift mutations, Proc. Natl. Acad. Sci. U.S.A. 100, 3895-3900.
-
(2003)
Proc. Natl. Acad. Sci. U.S.A.
, vol.100
, pp. 3895-3900
-
-
Johnson, S.J.1
Taylor, J.S.2
Beese, L.S.3
-
20
-
-
0037112082
-
Structural basis for the transition from initiation to elongation transcription in T7 RNA polymerase
-
Yin, Y. W., and Steitz, T. A. (2002) Structural basis for the transition from initiation to elongation transcription in T7 RNA polymerase, Science 298, 1387-1395.
-
(2002)
Science
, vol.298
, pp. 1387-1395
-
-
Yin, Y.W.1
Steitz, T.A.2
-
21
-
-
0033579380
-
Structure of a transcribing T7 RNA polymerase initiation complex
-
Cheetham, G. M., and Steitz, T. A. (1999) Structure of a transcribing T7 RNA polymerase initiation complex, Science 286, 2305-2309.
-
(1999)
Science
, vol.286
, pp. 2305-2309
-
-
Cheetham, G.M.1
Steitz, T.A.2
-
22
-
-
0032518398
-
Crystal structure of a bacteriophage T7 DNA replication complex at 2.2 A resolution
-
Doublie, S., Tabor, S., Long, A. M., Richardson, C. C., and Ellenberger, T. (1998) Crystal structure of a bacteriophage T7 DNA replication complex at 2. 2 A resolution, Nature 391, 251-258.
-
(1998)
Nature
, vol.391
, pp. 251-258
-
-
Doublie, S.1
Tabor, S.2
Long, A.M.3
Richardson, C.C.4
Ellenberger, T.5
-
23
-
-
0027231782
-
Structure of DNA polymerase I Klenow fragment bound to duplex DNA
-
Beese, L. S., Derbyshire, V., and Steitz, T. A. (1993) Structure of DNA polymerase I Klenow fragment bound to duplex DNA, Science 260, 352-355.
-
(1993)
Science
, vol.260
, pp. 352-355
-
-
Beese, L.S.1
Derbyshire, V.2
Steitz, T.A.3
-
24
-
-
0032535528
-
Crystal structures of open and closed forms of binary and ternary complexes of the large fragment of Thermus aquaticus DNA polymerase I: Structural basis for nucleotide incorporation
-
Li, Y., Korolev, S., and Waksman, G. (1998) Crystal structures of open and closed forms of binary and ternary complexes of the large fragment of Thermus aquaticus DNA polymerase I: Structural basis for nucleotide incorporation, EMBO J. 17, 7514-7525.
-
(1998)
EMBO J.
, vol.17
, pp. 7514-7525
-
-
Li, Y.1
Korolev, S.2
Waksman, G.3
-
25
-
-
0029817866
-
Crystal structures of human DNA polymerase beta complexed with DNA: Implications for catalytic mechanism, processivity, and fidelity
-
Pelletier, H., Sawaya, M. R., Wolfle, W., Wilson, S. H., and Kraut J. (1996) Crystal structures of human DNA polymerase beta complexed with DNA: implications for catalytic mechanism, processivity, and fidelity, Biochemistry 35, 12742-12761.
-
(1996)
Biochemistry
, vol.35
, pp. 12742-12761
-
-
Pelletier, H.1
Sawaya, M.R.2
Wolfle, W.3
Wilson, S.H.4
Kraut, J.5
-
26
-
-
0028049441
-
Structures of ternary complexes of rat DNA polymerase beta, a DNA template-primer, and ddCTP
-
Pelletier, H., Sawaya, M. R., Kumar, A., Wilson, S. H., and Kraut, J. (1994) Structures of ternary complexes of rat DNA polymerase beta, a DNA template-primer, and ddCTP, Science 264, 1891-18903.
-
(1994)
Science
, vol.264
, pp. 1891-18903
-
-
Pelletier, H.1
Sawaya, M.R.2
Kumar, A.3
Wilson, S.H.4
Kraut, J.5
-
27
-
-
0035826622
-
Insight into the catalytic mechanism of DNA polymerase beta: Structures of intermediate complexes
-
Arndt, J. W., Gong, W., Zhong, X., Showalter, A. K., Liu, J., Dunlap, C. A., Lin, Z., Paxson, C., Tsai, M.-D., and Chan, M. K. (2001) Insight into the catalytic mechanism of DNA polymerase beta: structures of intermediate complexes, Biochemistry 40, 5368-5375.
-
(2001)
Biochemistry
, vol.40
, pp. 5368-5375
-
-
Arndt, J.W.1
Gong, W.2
Zhong, X.3
Showalter, A.K.4
Liu, J.5
Dunlap, C.A.6
Lin, Z.7
Paxson, C.8
Tsai, M.-D.9
Chan, M.K.10
-
28
-
-
0030854581
-
Mechanism of ribose 2′-group discrimination by an RNA polymerase
-
Huang, Y., Eckstein, F., Padilla, R., and Sousa R. (1997) Mechanism of ribose 2′-group discrimination by an RNA polymerase, Biochemistry 36, 8231-8242.
-
(1997)
Biochemistry
, vol.36
, pp. 8231-8242
-
-
Huang, Y.1
Eckstein, F.2
Padilla, R.3
Sousa, R.4
-
29
-
-
0037183526
-
A reexamination of the nucleotide incorporation fidelity of DNA polymerases
-
Showalter, A. K., and Tsai, M.-D. (2002) A reexamination of the nucleotide incorporation fidelity of DNA polymerases, Biochemistry 41, 10571-10576.
-
(2002)
Biochemistry
, vol.41
, pp. 10571-10576
-
-
Showalter, A.K.1
Tsai, M.-D.2
-
30
-
-
0031587827
-
Crystal structure of a pol alpha family replication DNA polymerase from bacteriophage RB69
-
Wang, J., Sattar, A. K., Wang, C. C., Karam, J. D., Konigsberg, W. H., and Steitz, T. A. (1997) Crystal structure of a pol alpha family replication DNA polymerase from bacteriophage RB69, Cell 89, 1087-1099.
-
(1997)
Cell
, vol.89
, pp. 1087-1099
-
-
Wang, J.1
Sattar, A.K.2
Wang, C.C.3
Karam, J.D.4
Konigsberg, W.H.5
Steitz, T.A.6
-
31
-
-
0032584219
-
A single side chain prevents Escherichia coli DNA polymerase I (Klenow fragment) from incorporating ribonucleotides
-
Astatke, M., Ng, K., Grindley, N. D., and Joyce, C. M. (1998) A single side chain prevents Escherichia coli DNA polymerase I (Klenow fragment) from incorporating ribonucleotides, Proc. Natl. Acad. Sci. U.S.A. 95, 3402-3407.
-
(1998)
Proc. Natl. Acad. Sci. U.S.A.
, vol.95
, pp. 3402-3407
-
-
Astatke, M.1
Ng, K.2
Grindley, N.D.3
Joyce, C.M.4
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